Ca D3 Research Articles

ISPOL'ZOVANIE PREPARATOV KAL'TsIYa I VITAMINA D V KOMPLEKSE S ADEKVATNYM OSTEOSINTEZOM PRI PSEVDOARTROZAKh KOSTEY GOLENI

Expediency of the application of adequate osteosynthesis in combination with Ca + vitamin D intake for the treatment of pseudarthrosis (PA) complicated by regional immobilization osteoporosis was proved by the results of comparative study (treatment group - 23, control group - 33 subjects). Reliable decrease in time of consolidation by 15.3% was noted in treatment group as compared to controls. That decrease resulted from the transition of “lazy bone ” state typical for regional immobilization to a more active state of bone remodeling. Activization of remodeling process on with intake of Ca D3 Nycomed was proved by sigificant increase in the activity level of alkaline phosphatase and its isoenzyme acid phosphatase. Predominance of osteogenesis process over resorption in the early postoperative period was demonstrated by significant (p=0.004) increase in phosphatase index in the treatment group within first three months after operation as compared to the control group.

Ca 4Mg 4Fe 3H 22, a new quaternary transition metal hydride containing octahedral [FeH 6] 4− complex anions

Ca 4Mg 4Fe 3H 22 and its deuteride were synthesized by reaction of binary CaMg with iron wire at 500–530 °C and 100–155 bar hydrogen (deuterium) pressure. The cubic structure was established from X-ray single-crystal and neutron powder diffraction: space group P43 m, a=6.7151(6)Å (hydride) and 6.7016(4) Å (deuteride) at 295 K. It contains three types of deuterium atoms: two surrounding iron octahedrally with bond distances [Fe–4D1] = 1.583(3) A ̊ and [Fe–2D2] =1.562(5) A ̊ , and one situated in a tetrahedral hole formed by one magnesium and three calcium atoms with bond distances [Mg–D3] =1.808(7) A ̊ and [Ca–D3] = 2.388(9) A ̊ .