Wheat germ agglutinin crystallizes in two monoclinic space groups, P2 1 and C2, under identical crystallization conditions. Unit cell dimensions are a = 73.8 A ̊ , b = 51.2 A ̊ , c = 90.8 A ̊ , γ = 90 ° for P2 1; a = 51.31 A ̊ , b = 73.35 A ̊ , c = 91.45 A ̊ , β = 97.75 ° for C2, both with eight subunit molecules in the unit cell. The C2 crystals were chosen as suitable for investigating the three-dimensional structure to high resolution, because of their smaller asymmetric unit (containing the dimer), and also because they display better diffraction patterns.