In real-time data-intensive applications, achieving real-time data acquisition from sensors and simultaneous storage with the necessary performance is challenging, especially if "no-data-lost" requirements are present. Ad hoc solutions are generally expensive and suffer from a lack of modularity and scalability. In this work, we present a hardware/software platform built using commercial off-the-shelf elements, designed to acquire and store digitized signals captured from imaging spectrometers capable of supporting real-time data acquisition with stringent throughput requirements (sustained rates in the boundaries of 100 MBytes/s) and simultaneous information storage in a lossless fashion. The correct combination of commercial hardware components with a properly configured and optimized multithreaded software application has satisfied the requirements in determinism and capacity for processing and storing large amounts of information in real time, keeping the economic cost of the system low. This real-time data acquisition and storage system has been tested in different conditions and scenarios, being able to successfully capture 100,000 1 Mpx-sized images generated at a nominal speed of 23.5 MHz (input throughput of 94 Mbytes/s, 4 bytes acquired per pixel) and store the corresponding data (300 GBytes of data, 3 bytes stored per pixel) concurrently without any single byte of information lost or altered. The results indicate that, in terms of throughput and storage capacity, the proposed system delivers similar performance to data acquisition systems based on specialized hardware, but at a lower cost, and provides more flexibility and adaptation to changing requirements.