An extensive survey of Egyptian mammal burrows from Mersa Matruh on the Western Desert, through the Eastern Desert and Sinai Peninsula, and as far south as Asyut Province, has revealed an obviously rare, undescribed species of Ornithodoros tick from widely scattered localities in this area. Adults of the new species are readily distinguished by relatively small size, large cheeks, irregularly and narrowly ridged integument which gives them a wrinkled appearance, short and sparse body hairs, absence of dorsal humps on tarsi, and presence of a small but distinct subapical dorsal protuberance on tarsi II, III, and IV. These distinctive characters readily separate it from 0. tholozani tholozani (Laboulbene and Megnin), apparently its closest relative.