Miniature swine are sensitive and responsive animals for the study of burn shock resuscitation. In this model the sodium loads requisite for resuscitation of burned swine can exert roughly the same effect although with slower restoration of cardiac output when administered in volumes of 50–75% less than those commonly employed clinically. Sodium excretion is more dependent upon the sodium load than upon the concentration of the saline solution. Plasma had no demonstrable resuscitative effect over and above that provided by its volume and sodium content.