We applied the maximum likelihood method produced by Kijko and Sellevoll (Bull Seismol Soc Am 79:645–654, 1989; Bull Seismol Soc Am 82:120–134, 1992) to study the spatial distributions of seismicity and earthquake hazard parameters for the different regions in western Anatolia (WA). Since the historical earthquake data are very important for examining regional earthquake hazard parameters, a procedure that allows the use of either historical or instrumental data, or even a combination of the two has been applied in this study. By using this method, we estimated the earthquake hazard parameters, which include the maximum regional magnitude \( \hat{M}_{\max } , \) the activity rate of seismic events and the well-known \( \hat{b} \) value, which is the slope of the frequency-magnitude Gutenberg-Richter relationship. The whole examined area is divided into 15 different seismic regions based on their tectonic and seismotectonic regimes. The probabilities, return periods of earthquakes with a magnitude M ≥ m and the relative earthquake hazard level (defined as the index K) are also evaluated for each seismic region. Each of the computed earthquake hazard parameters is mapped on the different seismic regions to represent regional variation of these parameters. Furthermore, the investigated regions are classified into different seismic hazard level groups considering the K index. According to these maps and the classification of seismic hazard, the most seismically active regions in WA are 1, 8, 10 and 12 related to the Aliaga Fault and the Buyuk Menderes Graben, Aegean Arc and Aegean Islands.