We investigate the detailed response of gas to the formation of transient and long-lived dynamical structures induced in the early stages of a disk-disk collision, and identify observational signatures of radial gas inflow through a detailed examination of the collision simulation of an equal mass bulge dominated galaxy. Our analysis and discussion mainly focuses around the evolution of the diffuse and dense gas in the early stages of the collision, when the two disks are interacting but have not yet merged. Stars respond to the tidal interaction by forming both transient arms and long lived m = 2 bars, but the gas response is more transient, flowing directly toward the central regions within about 10 years after the initial collision. The rate of inflow declines when more than half of the total gas supply reaches the inner few kpc, where the gas forms a dense nuclear ring inside the stellar bar. The average gas inflow rate to the central 1.8 kpc is ∼ 7M⊙ yr −1 with a peak rate of 17M⊙ yr . Gas with high volume density is found in the inner parts of the post-collision disks at size scales close to the spatial resolution of the simulations, and this may be a direct result of shocks traced by the discontinuity in the gas velocity field. The evolution of gas in a bulgeless progenitor galaxy is also discussed, and a possible link to the “chain galaxy” population observed at high redshifts is inferred. The evolution of the structural parameters such as asymmetry and concentration of both stars and gas are studied in detail. Further, a new structure parameter (the compactness parameter K) that traces the evolution of the size scale of the gas relative to the stellar disk is introduced, and this may be a useful tracer to determine the merger chronology of colliding systems. Non-circular gas kinematics driven by the perturbation of the non-axisymmetric structure can produce distinct emission Department of Astronomy, University of Massachusetts, Amherst, MA 01002 Harvard-Smithsonian Center for Astrophysics, 60 Garden Street, Cambridge, MA 02138 Department of Astronomy, Case Western Reserve University, Cleveland, OH 44106 Research Corporation Cottrell Scholar and NSF CAREER Fellow