Buchowski Ksiazaczak Λh Model Research Articles

Experimental measurement and thermodynamic models for solid–liquid equilibrium of 3-amino-1-adamantanol in different pure solvents and in (H2O + ethanol) binary solvent mixtures

In this paper, we focused on solubility and solution thermodynamics of 3-amino-1-adamantanol. By gravimetric method, the solubility of 3-amino-1-adamantanol was measured in H2O, ethanol, methanol, n-propanol, n-butanol, tetrahydrofuran and (H2O+ethanol) binary solvent mixtures from 278.15K to 328.15K under atmosphere pressure. The solubility data of all solvent were fitted using modified Apelblat model and Buchowski–Ksiazaczak λh model. The solubility data of (H2O+ethanol) binary solvent mixtures were fitted using the two of the combined nearly ideal binary solvent/Redlich–Kister (CNIBS/R–K) model and Jouyban–Acree model. Computational results showed that the Apelblat equation provides a superior correlation in the pure solvent systems or the mixed solvent systems with a given initial composition. In addition, the thermodynamic properties of the solution process, including the Gibbs energy, enthalpy, and entropy were calculated by the van't Hoff analysis.

Thermodynamic models for determination of the solubility of omeprazole in pure and mixture organic solvents from T = (278.15 to 333.15) K

Data on corresponding (solid+liquid) equilibrium of omeprazole in different solvents are essential for a preliminary study of industrial applications. In this paper, the (solid+liquid) equilibrium of omeprazole in water, methanol, ethanol, 1-butanol, acetonitrile, acetone, ethyl acetate, tetrahydrofuran pure solvents and (tetrahydrofuran+ethyl acetate) mixture solvents were explored within the temperatures from 278.15K to 333.15K under atmosphere pressure. For the temperature range investigated, the solubility of omeprazole in the solvents increased with increasing temperature. From (278.15 to 333.15)K, the solubility of omeprazole in tetrahydrofuran is superior to other selected pure solvents. The modified Apelblat model, the Buchowski–Ksiazaczak λh model, and the ideal model were adopted to describe and predict the change tendency of solubility. Computational results showed that the modified Apelblat model has advantages than the other two models. Numerical values of the solubility were fitted using a modified Apelblat equation, a variant of the combined nearly ideal binary solvent/Redich–Kister (CNIBS/R–K) model and Jouyban–Acree model in (tetrahydrofuran+ethyl acetate) binary solvent mixture. Computational results showed that the CNIBS/R–K model is superior to the other equations. In addition, the calculated thermodynamic parameters indicate that in each solvent studied the dissolution of omeprazole is endothermic, non-spontaneous and is an entropy-driven process.

Solubility and Solution Thermodynamics of Gibberellin A4 in Different Organic Solvents from 278.15 K to 333.15 K

Data on corresponding solid–liquid equilibrium of Gibberellin A4 (GA4) in different solvents is essential for a preliminary study of industrial applications. In this paper, the solid–liquid equilibrium of GA4 in water, methanol, ethanol, isopropanol, 1-butanol, acetonitrile, acetone, and ethyl acetate was explored in the temperatures (from 278.15 K to 333.15 K) under atmosphere pressure. For the temperature range investigated, the solubility of GA4 in the solvents increased with increasing temperature. From 278.15 K to 333.15 K, the solubility of GA4 in isopropanol is superior to other selected solvents. The modified Apelblat model, the Buchowski–Ksiazaczak λh model, and the ideal model were adopted to describe and predict the change tendency of solubility. Computational results showed that the modified Apelblat model has advantages than the other two models. In addition, the calculated thermodynamic parameters indicated that in each studied solvent the dissolution of GA4 is endothermic, nonspontaneous, a...

Thermodynamic models for determination of the solubility of dl-malic acid in methanol plus (acetonitrile, N,N-dimethylformamide, isopropyl alcohol) binary solvent mixtures

The solubility of dl-malic acid in binary solvent mixtures consisting of (methanol+acetonitrile); (methanol+N,N-dimethylformamide); and (methanol+isopropyl alcohol) was measured at temperatures ranging from (278.15 to 328.15)K by gravimetric method. Values of the solubility were fitted using modified Apelblat equation and Buchowski–Ksiazaczak λh model. Computational results showed that the modified Apelblat equation was superior to the other equation. In addition, the thermodynamic properties of the solution process, including the Gibbs free energy, enthalpy, and entropy were calculated by the van’t Hoff analysis. This study provides valuable data for the dl-malic acid purification by the preferential crystallization procedure.

Experimental measurement and thermodynamic models for solid–liquid equilibrium of hyodeoxycholic acid in different organic solvents

Data on corresponding solid–liquid equilibrium of hyodeoxycholic acid (HDCA) in different solvents is essential for a preliminary study of industrial applications. In this paper, the solid–liquid equilibrium of HDCA in methanol, ethanol, isopropyl alcohol, butan-1-ol, ethyl acetate, acetone, acetonitrile, and acetic acid was explored at temperatures ranging from 278.15 to 333.15K under atmosphere pressure. For the temperature range investigated, the solubility of HDCA in the solvents increased with increasing temperature. The modified Apelblat model, the Buchowski–Ksiazaczak λh model, and ideal model were adopted to describe and predict the change tendency of solubility. Besides, the calculated thermodynamic parameters indicated that in each studied solvent the dissolution process of HDCA is endothermic. Based on the analysis above, ethanol is considered to be the best solvent in crystallization process of HDCA.

Thermodynamic Models for Determination of the Solubility of Sulfanilic Acid in Different Solvents at Temperatures from (278.15 to 328.15) K

Data on corresponding solid–liquid equilibria of sulfanilic acid in different organic solvents are essential for industrial design and further theoretical studies. In this study, the solubilities of sulfanilic acid were measured in methanol, ethanol, 2-propanol, acetone, acetonitrile, formic acid, and acetic acid with the temperature range of (278.15 to 328.15) K by the analytical stirred-flask method under atmospheric pressure. For the temperature range investigated, the solubility of sulfanilic acid in the solvents increased with increasing temperature. The thermodynamic models, such as the van’t Hoff model, the modified Apelblat model, and the Buchowski–Ksiazaczak λh model were investigated to describe the experimental data. It was found that the modified Apelblat model was the most suitable for predicting the solubility behavior of sulfanilic acid with increasing temperature. The calculated thermodynamic parameters indicated that in each studied solvent the dissolution process of sulfanilic acid is endothermic.

Thermodynamic Models for Determination of the Solubility of Dibenzothiophene in Different Solvents at Temperatures from (278.15 to 328.15) K

Data on corresponding solid–liquid equilibrium of dibenzothiophene (DBT) in different solvents are essential for a preliminary study of industrial applications. In this study, the solubility behavior of DBT in different solvents, such as methanol, ethanol, isopropyl alcohol, butan-1-ol, formic acid, and acetonitrile at temperatures ranging from (278.15 to 328.15) K was investigated. An analytical stirred-flask method was employed to measure the dissolubility of DBT. For the temperature range investigated, the solubility of dibenzothiophene in the solvents increased with increasing temperature. The thermodynamic models, such as the Van ‘t Hoff model, the modified Apelblat model and the Buchowski–Ksiazaczak λh model were investigated to describe the experimental data. It was found that the modified Apelblat model was the most suitable for predicting the solubility behavior of DBT with a temperature increment. The calculated thermodynamic parameters indicated that in each studied solvent the dissolution process of DBT is endothermic.

Solubility of 1-(3-Bromopropoxy)-4-Chlorobenzene in Aqueous Ethanol Mixtures From (273.15 to 303.15) K

1-(3-Bromopropoxy)-4-chlorobenzene is an important intermediate for the manufacture of omoconazole nitrate. The solubilities of 1-(3-bromopropoxy)-4-chlorobenzene in aqueous ethanol solutions were measured within the temperature range of (273.15–303.15) K using a laser monitoring system. For the temperature range investigated, the solubilities of 1-(3-bromopropoxy)-4-chlorobenzene in the aqueous ethanol mixtures increase with increasing temperature. The solubility data were regressed by the Buchowski–Ksiazaczak λh and the modified Apelblat models. The modified Apelblat equation and the Buchowski–Ksiazaczak λh equation provided accurate mathematical representations of the experimental results. The calculated solubilities showed good agreement with the experimental data. The root-mean-square deviations of the modified Apelblat model were lower than those of the Buchowski–Ksiazaczak λh model. This study provided valuable data for the purification of 1-(3-bromopropoxy)-4-chlorobenzene by crystallization.