Streptomycin and dihydrostreptomycin, with or without paraaminosalicylic acid (PAS), have revolutionized the treatment of tuberculosis, particularly in the field of otolaryngology. Sufficient favorable experience with these antibiotics has been accumulated in patients suffering from laryngeal or bronchial tuberculosis. Similar, if slightly less successful, results have been achieved in tuberculosis of the middle ear and pharynx. There remain some areas within our specialty where tuberculosis appears so infrequently that it becomes nearly impossible for a single observer to render a conclusive opinion regarding the therapeutic results obtained. It is the purpose of this paper to contribute to the scant literature existing on tuberculosis involving the maxillary sinus or the lip and tongue. At the same time the effects of streptomycin therapy, with or without PAS, in these lesions are recorded. A. TUBERCULOSIS OF THE MAXILLARY SINUS Purulent paranasal sinusitis of nonspecific origin occurs fairly frequently in the presence of pulmonary tuberculosis.