British Veterinary Association Research Articles

Assessing the impact of genomic selection against hip dysplasia in the Labrador Retriever dog.

Many purebred dogs exhibit a higher prevalence of inherited diseases compared with non-purebred dogs. One of the most popular breeds in the UK is the Labrador Retriever, which has a high prevalence of hip dysplasia resulting in high costs for surgical operations and impaired animal welfare. Considering the many complications of highly managed populations, mainly due to breeder's conventions and the resulting population structure, is of great importance for the proper development of a strategy against the disease. In this study, we have compared the utilities and performances of both genomic and phenotypic selection against hip dysplasia in a simulated population with the characteristics of the British Veterinary Association and Kennel Club (BVA/KC) hip dysplasia scheme. The results confirm the potential benefits of genomic selection by showing a moderate increase of 1.15-fold (assuming a realistic accuracy of r2 = 0.5) in response to selection due to the higher accuracy (between 0.96- and 1.32-fold, considering 0.35 ≤ r2 ≤ 0.7) and more than a threefold increase when all the offspring in each litter are tested (between 3.25- and 4.55-fold, again considering 0.35 ≤ r2 ≤ 0.7).

British Veterinary Association

British Veterinary Association

British Veterinary Association

British Veterinary Association

Opportunities for international collaboration in dog breeding from the sharing of pedigree and health data

Pooling of pedigree and phenotype data from different countries may improve the accuracy of derived indicators of both genetic diversity and genetic merit of traits of interest. This study demonstrates significant migration of individuals of four pedigree dog breeds between Sweden and the United Kingdom. Correlations of estimates of genetic merit (estimated breeding values, EBVs) for the Fédération Cynologique Internationale and the British Veterinary Association and Kennel Club evaluations of hip dysplasia (HD) were strong and favourable, indicating that both scoring schemes capture substantially the same genetic trait. Therefore pooled use of phenotypic data on hip dysplasia would be expected to improve the accuracy of EBV for HD in both countries due to increased sample data.

British Veterinary Association

British Veterinary Association

British Veterinary Association

British Veterinary Association

British Veterinary Association

Veterinary RecordVolume 172, Issue 14 p. 369-369 Gazette British Veterinary Association First published: 06 April 2013 https://doi.org/10.1136/vr.f2068Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat No abstract is available for this article. Volume172, Issue14April 2013Pages 369-369 RelatedInformation

British Veterinary Association

British Veterinary Association

Should anthelmintics be restricted to POM-V classification?

The British Veterinary Association recently released a statement requesting that all anthelmintics become prescription only medicines. Nicola Ackerman, a veterinary nurse who has worked in large animal practice, and an SQP, discusses what this means.

British Veterinary Association

Veterinary RecordVolume 172, Issue 7 p. 188-188 Gazette British Veterinary Association First published: 16 February 2013 https://doi.org/10.1136/vr.f999Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat No abstract is available for this article. Volume172, Issue7February 2013Pages 188-188 RelatedInformation

British Small Animal Veterinary Association ‘The Company’ Annual General Meeting

Journal of Small Animal PracticeVolume 54, Issue 1 p. 46-56 BSAVA BUSINESS British Small Animal Veterinary Association ‘The Company’ Annual General Meeting First published: 26 December 2012 https://doi.org/10.1111/jsap.12005.xRead the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat Volume54, Issue1January 2013Pages 46-56 RelatedInformation

British Veterinary Association annual general meeting, 2012

The 2012 annual general meeting of the British Veterinary Association was held at the Merseyside Maritime Museum, Liverpool, on September 29, at the end of the Association's annual congress

British Veterinary Association

British Veterinary Association

British Veterinary Association

Veterinary RecordVolume 171, Issue 6 p. 158-158 Gazette British Veterinary Association First published: 11 August 2012 https://doi.org/10.1136/vr.e5361Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full...

British Veterinary Association

British Veterinary Association

British Veterinary Association

Veterinary RecordVolume 171, Issue 4 p. 103-103 Gazette British Veterinary Association First published: 28 July 2012 https://doi.org/10.1136/vr.e5062Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full...

British Veterinary Association

British Veterinary Association

British Veterinary Association

Veterinary RecordVolume 171, Issue 2 p. 49-49 Gazette British Veterinary Association First published: 14 July 2012 https://doi.org/10.1136/vr.e4830Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full...

British Veterinary Association

British Veterinary Association

Heritability and phenotypic variation of canine hip dysplasia radiographic traits in a cohort of Australian German shepherd dogs.

Canine Hip Dysplasia (CHD) is a common, painful and debilitating orthopaedic disorder of dogs with a partly genetic, multifactorial aetiology. Worldwide, potential breeding dogs are evaluated for CHD using radiographically based screening schemes such as the nine ordinally-scored British Veterinary Association Hip Traits (BVAHTs). The effectiveness of selective breeding based on screening results requires that a significant proportion of the phenotypic variation is caused by the presence of favourable alleles segregating in the population. This proportion, heritability, was measured in a cohort of 13,124 Australian German Shepherd Dogs born between 1976 and 2005, displaying phenotypic variation for BVAHTs, using ordinal, linear and binary mixed models fitted by a Restricted Maximum Likelihood method. Heritability estimates for the nine BVAHTs ranged from 0.14–0.24 (ordinal models), 0.14–0.25 (linear models) and 0.12–0.40 (binary models). Heritability for the summed BVAHT phenotype was 0.30±0.02. The presence of heritable variation demonstrates that selection based on BVAHTs has the potential to improve BVAHT scores in the population. Assuming a genetic correlation between BVAHT scores and CHD-related pain and dysfunction, the welfare of Australian German Shepherds can be improved by continuing to consider BVAHT scores in the selection of breeding dogs, but that as heritability values are only moderate in magnitude the accuracy, and effectiveness, of selection could be improved by the use of Estimated Breeding Values in preference to solely phenotype based selection of breeding animals.