Break Barriers Research Articles

Identifying ecological and evolutionary research targets and risks in climate change studies to break barriers to broad inference

Understanding the responses of plants, microbes, and their interactions to long-term climate change is essential to identifying the traits, genes, and functions of organisms that maintain ecosystem stability and function of the biosphere. However, many studies investigating organismal responses to climate change are limited in their scope along several key ecological, evolutionary, and environmental axes, creating barriers to broader inference. Broad inference, or the ability to apply and validate findings across these axes, is a vital component of achieving climate preparedness in the future. Breaking barriers to broad inference requires accurate cross-ecosystem interpretability and the identification of reliable frameworks for how these responses will manifest. Current approaches have generated a valuable, yet sometimes contradictory or context dependent, understanding of responses to climate change factors from the organismal- to ecosystem-level. In this synthesis, we use plants, soil microbial communities, and their interactions as examples to identify five major barriers to broad inference and resultant target research areas. We also explain risks associated with disregarding these barriers to broad inference and potential approaches to overcoming them. Developing and funding experimental frameworks that integrate basic ecological and evolutionary principles and are designed to capture broad inference across levels of organization is necessary to further our understanding of climate change on large scales.

한국 무속에서 읽어낸 그로토프스키의 세속적 신성

This study explores the convergence of Jergy Grotowski's ‘Secular sacrum in the theatre’ and Korean Muism(Korean Shamanism)’s shamanic rituals in the context of secular spirituality. Grotowski advocates for the theatrical stage as a sacred space, breaking barriers for genuine inner exploration, with the ‘holy actor’ crucial for manifesting secular spirituality. Drawing parallels, Muism’s shamans(mudang) embody the ‘holy actor’ through acts like ‘self-sacrifice’ and ‘emptying oneself’, seen in rituals such as the initiation ceremony(Naerim Gut). The shaman, bridging the divine and human realms, seeks to heal through spiritual power in a sacred space. Embedded in Korean culture, Gut rituals serve as a pillar of secular spirituality, transforming the worldly into the sacred. The shaman(mudang), a key practitioner, orchestrates these spiritual rituals, playing a central role in communal life.

IPSOS trial: A “game changer” redefining first-line immunotherapy in platinum-ineligible NSCLC

First-line therapy for advanced non-small cell lung cancer (NSCLC) involves immunotherapy with or without platinum-based chemotherapy; however, not all patients are fit enough. In the IPSOS trial, atezolizumab monotherapy demonstrated a clinical benefit in platinum-ineligible patients with advanced NSCLC, redefining first-line immunotherapy, and breaking barriers for unfit population in NSCLC.

Barriers to Recruitment of Women to South African Mining Boards

Mining as a historically male-dominated industry in South Africa has legacy issues stemming from colonisation and apartheid, which contributed to gender (and racial) disparities. To address these disparities, corrective measures in the post-apartheid legislation and government policies have aimed to promote equal participation of women in the mining industry at all levels, including key leadership positions such as board memberships. However, despite two decades of enforced legislation, the representation of women in boardrooms remains below 22%. To better understand this issue, qualitative research was conducted through interviews with 28 directors in the South African mining industry. These interviews delved into the recruitment process and the criteria used for selecting directors within the industry. Nkomo and Ngambi’s meso-level framework guided the identification and classification of barriers reported in the literature on obstacles impeding women’s appointment to boards at individual/psychological, organisational/structural, and social/societal levels. Thematic analysis showed the prevalence of organisational and structural prejudices and barriers in the recruitment process and criteria. The male-dominated nomination committees drive recruitment by selecting acquaintances from their own networks whom they overpower in decision-making. This network reinforces the old boys’ club and glass ceilings, contributing to the lower confidence of women. This research recommends organisational structural policy-level changes to accelerate female board recruitment by imposing at least 40% female board representation. A balanced gender role combination of chief executive officer and chairman positions on each board is likely to break barriers associated with the male-dominated boardroom culture and practices.

Virtual Reality for Supporting Knowledge Sharing: An Exercise of Technology Assessment

Knowledge sharing is an important process in knowledge management to foster collaboration. For itseffective management, it is often suggested to use the support of adequate technologies. Virtual reality (VR) is a promising technology whose application in business increasingly attracts attention in activities, such as business meetings or training, where participants need to share knowledge in a complex context with communicational, social, and management implications. Due to the immersive capabilities, VR may provide new ways of sharing knowledge. However, due to the novelty of this technology, research is needed to evaluate its potential and drawbacks. This study aims to contribute to further understanding of whether and how the introduction of VR in organizations can favour knowledge sharing and collaboration between employees and to evaluate its potential, challenges, and prospects. It is based on a qualitative exercise of technology assessment based on two approaches: technology monitoring and collection of expert opinions using interviews with experts in organisations specialised in VR. Our analysis shows that VR has the potential to break barriers of time and space that may hinder effective human interactions. It can simplify the sharing of notions, data, and, more generally, knowledge, and allow people to connect and communicate as active protagonists. However, adopting VR may require organisational changes and has some limitations. In addition,appropriate knowledge-sharing models for VR applications still need to be developed. Consequently, our paper argues that although much is possible today with VR, further developments are still needed for this technology to reach complete maturity.

Curative handcrafted textiles: Healing generations

While natural disasters in the past, along with the recent COVID-19 pandemic, have disrupted livelihoods, they have also activated the structuring of handicraft as an age-old remedial practice with curative properties. Further, the need for communicating textile processes, in support of slow fashion, has allowed educational institutions to contextualize this teaching with the help of pedagogical models that define the role of both craft education and craft-based research. As an educator at Pearl Academy, India, what I can observe in the modern world today is that there is always a cross-cultural contact between the ‘local’ and the ‘global’ and that, the much-discussed ‘global village’ is no longer a fantasy but a fact, despite numerous paradoxes. This article aims at giving an insight into my perspectives and experiences that shed light on the plight of handicraft in the most hand-skilled country in the world. It also lends a bird’s-eye point of view on the need to break barriers between modern and traditional, between urban and rural, etc., and look at the many avatars of handicraft and techniques being repurposed for modern applications such as luxury fashion, interior design and jewellery. This can result in the creation of works that are not only aesthetically pleasing but are also functional, sustainable and culturally sensitive and can help designers and artists navigate complex ethical issues that resonate with diverse communities. The article takes into consideration handcrafted textile samples developed by three postgraduate fashion design students at Pearl Academy, India, who have developed textile samples as part of their project called ‘Hybrid Textiles’. The samples create an epilogue to the context of this study through an ‘end of life’ narrative and craft practices in India.

Fish gelatin films incorporated with cinnamaldehyde and its sulfobutyl ether-β-cyclodextrin inclusion complex and their application in fish preservation.

For food preservation, the packaging film needs to have higher antibacterial activity in initial phase and keep longer activity. In this study, cinnamaldehyde (CA) and its sulfobutyl ether-β-cyclodextrin inclusion complex (CA/S) were used to fabricate fish gelatin antibacterial composite films. The addition enhanced the elongation at break and light barrier property of the films. Film forming solution incorporated with CA and CA/S presented the most excellent inhibition ratio against Pseudomonas aeruginosa, which was 98.43±1.11% in initial period and still 82.97±4.55% at 72h. Further, the packaging solution of gelatin combined CA and CA/S effectively inhibited the growth of microorganisms during preservation of grass carp slices. Especially, the total volatile salt-based nitrogen (TVB-N) did not exceed 10mg/100g at the end of storage, indicating that the active coating could obviously extend the shelf life of fish muscle. This work provided a promising food packaging system with antimicrobial and environmentally friendly.

Female journalists who have reached the top: perceptions on communication, leadership, and gender bias in the Portuguese press

PurposeThe purpose of this study is to understand challenges and constraints in reaching top leadership positions for women in the Portuguese press. Specifically, it aims at characterizing their communication and leadership styles, and at identifying main gender biases in newsrooms routines from their point of view.Design/methodology/approachA qualitative method was employed by conducting in-depth interviews with four women who have held higher management positions in Portuguese leading newspapers. Participants were asked to characterize their communication and leadership style, but also newsrooms environment, trying to understand how gender asymmetries persist and manifest. Results were analyzed using thematic analysis.FindingsWhile considering that Portuguese newsrooms are no longer environments marked by a sexist/macho environment, through increasing female participation, women still represent a minority in leadership. Leadership traits linked to male styles, including assertiveness and courage, were revealed, though mixed with a more participative/relational leadership. Also, female leaders regret when emotional ties with teams are not developed and recognized some degree of privilege towards other women through family support or not having children.Research limitations/implicationsThere is a limited number of interviews, although they represent the few top women leaders in Portuguese journalism.Practical implicationsPolicymaking recommendations derived from conclusions include participative leadership, implementing quotas, and monitoring tools of gender biases and special training.Social implicationsMedia literacy policies and open debates on main media outlets concerning female leadership and communication styles may contributes toward the acknowledgement of lingering gender biases in the industry.Originality/valueThis study contributes to a fuller insight into the identification of leadership and personal traits among women who managed to disrupt stigmas and break barriers. Their voices are seldom heard in studies focusing leadership, so results enable ascertaining whether there is a female way of leading in journalism and comprehending the sense of privilege these women perceive.

Tattoos & 6-Inch Heels: A Visual Exploration of the Meaning of Clothing for Adults With Mobility Disabilities

Abstract Date Presented 04/22/2023 A PhotoVoice study exploring the meaning of clothing for disabled adults yielded four themes: adaptations–innovations, trade-offs, being excluded, and breaking barriers. Adaptive clothing was seen as a barrier, raising concerns for OT intervention. Primary Author and Speaker: Chris Simmons Additional Authors and Speakers: Celine Saba Rezvani, Sheryl Ryan Contributing Authors: Ramon Ronquillo, Khanh Phan

The Cyperus esculentus starch‐based bioactive films: characterisation, UV‐shielding and antioxidant capacity

SummaryThis study aimed to develop a novel antioxidant film for food packaging based on Cyperus esculentus starch and thymol. The mechanical, physicochemical and antioxidant properties of composite films were investigated. The C. esculentus starch showed good film‐forming properties. Incorporating of thymol improved the elongation at break and ultraviolet barrier property of the films, meanwhile decreased the moisture content of the films. Scanning electron microscopy showed good compatibility between starch matrix and thymol. The formation of hydrogen bonds between starch and thymol was confirmed by Fourier transform infrared spectroscopy and X‐ray diffraction. The composite films (3% thymol) exhibited higher antioxidant with DPPH scavenging capacity values of 73.22 ± 2.05% compared with control films. This study provided a potential unconventional starch for the preparation of bioactive films.

Spatial-temporal evolution pattern and optimization path of family education policy: An LDA thematic model approach

Family education policy plays a crucial role in modernizing family education. By examining the temporal and spatial evolution of this policy, its inherent logic, constructs, and optimal pathways can be better understood. The study analyzed local family education policy documents, extracting six major themes using the Latent Dirichlet Allocation (LDA) model, and presented them according to the calculated mean theme probability. The themes include parental ability, school security, institutional environment, government support, social coordination, and high-quality development. Parental ability and government support were found to be particularly prominent, suggesting that many local policies focus on enhancing parents' skills for delivering family education and bolstering the government's role in public affairs. This combines the dual responsibilities of being an educational entity and accountable subject in the joint development of family education. Understanding the characteristics and variations in temporal and spatial distribution can enrich family education policy design, fostering the high-quality development of family education initiatives. Based on the findings, the study proposes three optimization paths for policy design: promotion and empowerment (building a multi-cooperative system), regional interconnection (understanding the current state of local policies and leveraging their strengths), and breaking barriers (simultaneously promoting the inclusiveness of family education and brand development). This study emphasizes the needs of customizing family education policy based on the temporal and spatial features and local requirements for maximum outputs.

Break barriers in soil data stewardship by rewarding data generators

Break barriers in soil data stewardship by rewarding data generators

Impact of ethnobiology-based instruction and peer tutoring on the achievement of senior secondary school biology students in Ogun state southwest Nigeria

This study investigated the impact of Ethnobiology-Based instruction Peer Tutoring on Achievement of Senior Secondary School Biology Students in Ogun State. The study employed Explanatory sequential mixed-methods approach. The quantitative approach was quasi experimental pretest-posttest non-equivalent group design. Three research questions and one hypothesis was formulated to guide the study. The population of the study comprised of all Biology students in public Senior Secondary Schools in Abeokuta zone. Purposive sampling technique was used to select six Public Schools from two zones (Abeokuta South and Abeokuta North). Biology students in six intact classes of SSS III took part in the study. The sample size of 313 biology students with 101 students in the experimental group 1 (48 male and 53 female), 117 students in the experimental group 2 (57 male and 60 female) and 95 students in control group (38 male and 57 female) which were taught the same biology content for a period of four weeks. The experimental groups received instructions through the use of Ethnobiology-Based Instruction and Peer Tutoring while the control group was taught using lecture method. The data gathering instruments were Biology Achievement Test (BAT) and Students Semi-structured Interview Guide (SSIG). The reliability coefficient of the BAT was established using test- retest and yielded 0.87. Descriptive statistics in form of mean, standard deviation and histogram plot were used to answer the research question while the hypothesis was tested using ANCOVA at 0.05 level of significance. The inferential analysis of hypothesis one has a significant difference on Students’ academic achievement in Biology (F (2,309) = 386.85; p < 0.05), this indicated that the hypothesis is hereby rejected since a significant difference is obtained. The results from the study revealed that the treatments positively improved the academic achievements of students and the students taught using ethnobiology-based instruction had higher test result and outperformed those in Peer Tutoring and lecture method group, but the students in Peer tutoring group also performed better than those in lecture method group. This implies that Ethnobiology-Based instruction is more effective in enhancing Students’ performance in biology and it helps to break barriers to meaningful learning of biology. Based on the findings of this study, it was recommended that Biology teachers should relate learning to students’ cultural views and encourage peer tutoring.

Self-Management and Glycemic Targets in Adult Haitian Immigrants With Type 2 Diabetes: Research Protocol.

Type 2 diabetes (T2D) is a chronic condition affecting more than 34.2 million U.S. adults, and people of African descent have a disproportionate burden. Haitian immigrants' unique cultural and biological factors put them at elevated risk for T2D-related complications. Despite prior research highlighting the success of multimethod approaches to T2D self-management behaviors on glycemic targets, a dearth of studies have used these methods to improve diabetes self-management in this marginalized population. This article describes a repeated-measures design protocol of a going study about self-management behaviors among adult Haitian immigrants with T2D and characterizing their barriers to T2D self-management. We will enroll 100 Haitian immigrants aged 18-64 years who have lived with T2D for at least 1 year. Using multiple recruitment methods and Research Electronic Data Capture, subjective and objective data on T2D self-management practices, glucose variability via continuous glucose monitor, and a comprehensive view of physical activity via actigraphy are collected. Data analysis will follow a two-part approach mirroring the two primary study objectives. Findings from the study will guide the development and testing of a culturally tailored diabetes self-management education program that will contribute essential information about best practices for this population and break barriers that may impede research on unique individuals and subsequent effective self-management.

Challenges of Deep Learning in Medical Image Analysis—Improving Explainability and Trust

Deep learning has revolutionized the detection of diseases and is helping the healthcare sector break barriers in terms of accuracy and robustness to achieve efficient and robust computer-aided diagnostic systems. The application of deep learning techniques empowers automated AI-based utilities requiring minimal human supervision to perform any task related to medical diagnosis of fractures, tumors, and internal hemorrhage; preoperative planning; intra-operative guidance, etc. However, deep learning faces some major threats to the flourishing healthcare domain. This paper traverses the major challenges that the deep learning community of researchers and engineers faces, particularly in medical image diagnosis, like the unavailability of balanced annotated medical image data, adversarial attacks faced by deep neural networks and architectures due to noisy medical image data, a lack of trustability among users and patients, and ethical and privacy issues related to medical data. This study explores the possibilities of AI autonomy in healthcare by overcoming the concerns about trust that society has in autonomous intelligent systems.

“Winning the Hearts and Minds”: The Intellectual Cold War and the Rockefeller and Ford Foundations’ Exchange Programs in Eastern Europe

At the end of World War II, American private foundations hoped to restore the pre-war relations with the research institutes, universities, and individual scholars in Europe. The Iron Curtain that divided the continent prevented a further expansion of their programs. Planned for the betterment of humankind, to improve health and education, advance scientific research, and facilitate worldwide scientific cooperation, the foundations’ exchange programs aimed at breaking barriers, overcoming differences, and leading to international understanding. However, in the new geopolitical circumstances, they served other purposes. By providing access to knowledge and different perspectives on ideas and values, the exchange programs contributed to the formation of the elite intellectual networks that undermined and finally brought Communism down. This article provides an insight into the reasons for the two foundations’ early involvement in Eastern Europe and their distinct methods and compares these to the public diplomacy efforts. It also discusses the radically different reception of activities undertaken by public and private organizations that strengthened the plea for the “hearts and minds” of the people behind the Iron Curtain.

High strength, controlled release of curcumin-loaded ZIF-8/chitosan/zein film with excellence gas barrier and antibacterial activity for litchi preservation

Polysaccharide films containing protein additives have good application prospects in agriculture and food field. However, interfacial incompatibility between hydrophobic proteins and hydrophilic polymers remains a major technical challenge. In this work, the interfacial compatibility between hydrophobic zein and hydrophilic chitosan (CS) is improved by the chemical crosslinking between zinc ions of curcumin-loaded zeolitic imidazolate framework-8 (Cur-ZIF-8) with CS and zein. With the improvement of interface compatibility, the results show that the elongation at break and O2 barrier property of synthesized Cur-ZIF-8/CS/Zein are 9.2 and 1.5 times higher than CS/Zein, respectively. And the Cur-ZIF-8/CS/Zein exhibits superior antibacterial and antioxidant properties as well. Importantly, Cur-ZIF-8/CS/Zein can also be used as an intelligent-responsive release platform for curcumin. As a result, Cur-ZIF-8/CS/Zein can keep the freshness and appearance of litchi at least 8 days longer than that of CS/Zein. Therefore, this study provides a novel method to improve the interfacial compatibility between hydrophobic proteins and hydrophilic polymers, and is expected to expand the application of protein/polymer composites in agriculture and food field.

Abstract B088: The Alabama Hereditary Cancer Cohort – New strategies for African American recruitment

Abstract Our group has established the Alabama Hereditary Cancer Cohort and primarily investigates breast cancer genetics in African American, an underrepresented group in biomedical research. Alabama has double the national percentage of African Americans and is the location of the infamous and unethical Tuskegee Syphilis Study. Therefore, strategic protocols were developed to break research participation barriers, effectively recruiting African American hereditary breast cancer cases and families. Our initial recruitment strategies involved both hospital-based and community-based recruitment; the latter involved our recruitment bus, the Gene Machine, and focused on African American engagement. Since our initial publication, our community-based recruitment protocol has been modified. Many of the modifications were due to the pandemic, limiting in-person community engagement. In-person education seminars and enrollment sessions transitioned to virtual meetings, using various video-conferencing platforms. Regarding virtual enrollments, upon agreement to proceed with the virtual consent process, study participants are mailed an enrollment kit containing study consent forms, saliva collection kits, return mailing materials, and instructions. Once received, an enrollment appointment is made, and the consent process follows the procedure for in-person study enrollment, concluding with the saliva sample collection. Once collected, the sample is packaged with the consent forms and returned to our laboratory in the postage-paid mailer. Community-based recruitment has also been enhanced by partnering with the Alabama Department of Public Health to identify study participants through the Alabama Statewide Cancer Registry, similar to the very successful Carolina Breast Cancer Study. Furthermore, Research Champions have been added to the protocol, defined as primary healthcare providers and specialists who aid in recruitment by identifying individuals who fit the study criteria. The concept of Research Champions was developed after recognizing that the requirements to execute hospital-based recruitment are arduous on partnering hospitals. Thus, the sole function of a Research Champion is identifying prospective study participants, relieving the burden on physicians and hospital staff. Lastly, our Gene Machine Facebook page and newly designed website, tailored towards laypeople/study participants, facilitate additional engagement through ads, videos, and photos. Ultimately, these processes reduce the travel burden, aid in social distancing, and expand our reach, enhancing recruitment and enrollment efforts and breaking barriers to African American research. Citation Format: Nancy Merner, Elizabeth Stallworth, Erica Reasor, Katia Khoury, Lily Gutnik, Meagan Farmer, Brandon Johnson. The Alabama Hereditary Cancer Cohort – New strategies for African American recruitment [abstract]. In: Proceedings of the 15th AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved; 2022 Sep 16-19; Philadelphia, PA. Philadelphia (PA): AACR; Cancer Epidemiol Biomarkers Prev 2022;31(1 Suppl):Abstract nr B088.

Building confidence in STEM students through breaking (unseen) barriers

Abstract. Science, technology, engineering, and math (STEM) subjects have historically struggled to be inclusive and accessible to students from diverse backgrounds. The field of geoscience, in particular, has also had challenges in diversity with respect to staff and student recruitment. The consequence of non-inclusive practices still propagates today, with certain demographics not engaging in STEM activities. As a result, there needs to be conscious efforts to adopt equity, diversity, and inclusive (EDI) initiatives for subjects such as geoscience to grow. In this article, we outline the steps we have taken to break down known (and unknown) barriers to education in the teaching of a science outreach course to a diverse student body. Our outreach course, Think Like A Scientist, has been running in a number of English prisons since 2019. Although the programme is tailored to the restrictive prison environment, the application of its core principles to education are fundamental EDI practices that could be beneficial to a wide audience. In this paper, we outline our reasoning for specific pedagogical choices in the classroom when working with students that have low confidence in STEM education, and we highlight the need for engagement that is not only relatable, accessible, and inclusive but also offers encouragement.

Effect of different starch contents on physical, morphological, mechanical, barrier, and biodegradation properties of tapioca starch and poly(butylene adipate‐co‐terephthalate) blend film

AbstractStudy on degradation behaviors of biodegradable poly(butylene adipate‐co‐terephthalate) (PBAT) blended with different compositions of thermoplastic starch (TPS) under soil burial and natural weathering environments is vital in order to predict the product service‐life and planning for in situ biodegradation after product disposal. In this article, different compositions of TPS (0%, 20%, 40%, 50%, and 60%) were compounded with PBAT using single screw extruder. The samples were characterized for their tensile properties, fractured surface morphology, water barrier and surface hydrophorbicity properties in order to investigate the effect of starch fractions in PBAT blends. The degradation behavior under natural weathering and soil burial conditions was also determined during the 9 months duration by observing the change of physical appearance, weight loss, surface morphology, chemical structural, and tensile properties. The findings showed that the addition of TPS (20%, 40%, 50%, and 60%) had led to a reduction in tensile strength (41.47%, 60.53%, 63.43%, and 68.53%), and reduction in elongation at break (42.92%, 92.1%, 92.23%, and 93.22%, respectively) and water barrier properties. The findings also showed that there were distinct degradation behavior under both conditions. Upon exposure to natural weathering, photodegradation and Norrish type I & II occurred whereas under the soil burial condition, hydrolytic, and enzymatic degradation take places. Sample with the highest starch contents underwent the highest weight loss and reduction in tensile properties under both environments. The findings in this study are useful in order to investigate the feasibility of PBAT/Tapioca starch blends for biodegradable plastic film for various industrial applications especially in packaging and agricultural mulch.