The growth and productivity of drought-prone varieties are strongly influenced by the chlorophyll pigment content and the development of plants’ foliage. The current climate changing, characterized by long no-rain periods followed by short intense rainfalls, is forcing plants to adopt different strategies to cope with drought. The purpose of the current study is to estimate the effect of growing conditions on the indicators of the total leaf area, leaf surface index (LSI) of sowing, the concentration of chlorophylls (Chl) in the leaves and the yield of winter wheat, depending on the value of their moisture supply. There have been established that the leaf surface index change and the preservation of chlorophyll pigment in foliage during the vegetation period is closely related to plants’ drought resistance, soil moisture reserve and a genotype. Under conditions of insufficient moisture supply, the maximum values of the leaf surface index in the heading phase were formed by the varieties ‘Krasa Dona’ (5.99 r.u) and ‘Etyud’ (2.49 r.u.). The highest content of chlorophyll pigment, both in the heading phase and in the flowering phase, was identified in the varieties ‘Krasa Dona’ (3.7; 3.0 mg/100 g of raw material), ‘Etyud’ (3.4; 3.2 mg/100 g of raw material) and ‘Volny Don’ (3.2; 3.0 mg/100 g of raw material), respectively. Acording to the value of productivity, the reliably standard variety ‘Don 107’ has exceeded the varieties ‘Etyud’, ‘Krasa Dona’, ‘Asket’, ‘Volny Don’.