Brand Research Articles

Tuning Element Distribution, Structure and Properties Using the SPSS Method

The term "structural elements" refers to the roof, slab, beams, columns, girders, and other structural components and connections, both inside and outside of the exterior walls, window frames, and doors, as well as all other components that make up the building's framework. Structural components may include load-bearing brick or cement walls, dust walls, or made from wood partitions that are both outside and inside; " Stone, brick, or concrete vaults; cast-iron, stone, or concrete columns; Beams, trusses, and girders made of wood, iron, or metal" so forth. Structural layout is critical in civil engineering as it allows to test whether or not the shape is secure. Structural layout presents all important records about foundations, floors, partitions, beams, roof types and fine of substances. Structural methods are divided into two main groups, static and dynamic. Things that change will be discussed in the next section. Fixed structures often have fixed parts in relation to each other. The entire structure, like the main truss of the International Space Station, can move with respect to the ground. Fundamental analysis represents The starting place of chemical knowledge. It has furnished important facts about substances and their composition for the reason that the start of the development of chemical concepts and technology in wellknown. Based on natural compounds which include physical fluids, chemical compounds, ingesting water, minerals, soil or waste, elemental analysis can screen critical facts that may be used to tell scientists approximately the health, protection and health of a person or the environment. Drinking water fine and our chemistry. The 4 elements of fire, earth, air and water are the inspiration of life. The warmness of the sun, the earth beneath our toes, the air we breathe and the water we drink are essential to our existence. They exist in a harmonious balance, and this balance is important for us and the planet to live on. SPSS statistics is a multivariate analytics, business intelligence, and criminal investigation data management, advanced analytics, developed by IBM for a statistical software package. A long time, spa inc. Was created by, IBM purchased it in 2009. The brand name for the most recent versions is IBM SPSS statistics. Interstitial Complex, Multiple Configurations, Reversible Reactions, Large Lattice Relaxation, Recombination Enhanced Reactions, Temperature Dependent o~m~j and Large Stokes Shift. The Cronbach's Alpha Reliability result. The overall Cronbach's Alpha value for the model is .744 which indicates 74% reliability. From the literature review, the above 50% Cronbach's Alpha value model can be considered for analysis. The Cronbach's Alpha Reliability result. The overall Cronbach's Alpha value for the model is .744 which indicates 74% reliability. From the literature review, the above 50% Cronbach's Alpha value model can be considered for analysis.Interstitial Complex, Multiple Configurations, Reversible Reactions, Large Lattice Relaxation and Recombination Enhanced Reactions.

Name order effects on cobrand perceptions: the impacts of product similarity and language structure

PurposeThe Islamic world spans many different languages with different language structures. This paper aims to explore one way in which language structure affects consumer response to the marketing of cobrands.Design/methodology/approachTwo between subject experiments were conducted using samples of participants from Saudi Arabia and the USA. The first manipulated partner brand category similarity and brand name order, along with the structure of the language used to communicate with the market. The data for this study includes Arabic speakers in Saudi Arabia as well as English speakers in the USA. The second study explores how targeting a population fluent in multiple languages of varied structure nullifies the findings from the first study and uses Latino participants in the USA.FindingsThis study finds that when brands come from similar product categories, name order did not affect cobrand evaluations, but it did when the brands come from dissimilar product categories. Here, evaluations of the cobrand are enhanced when the invited brand is in the position that adjectives occupy in the participant’s language. The authors also find that being proficient in two languages, each with a different default order for adjectives and nouns, quashes the effect of name order otherwise seen when brands from dissimilar product categories engage in cobranding.Originality/valueBy examining the impact of language structure on the effects of cobrand evaluation and conducting studies among participants with differing dominant languages, this research can rule out simple primacy or recency effects.

Time to ‘Wine’: A Content Analysis Investigating How Social Media Influencers Refer to Alcohol Use in Instagram’s Feed Posts and Stories

ABSTRACT This exploratory content analysis examines how well-known social media influencers (SMIs) refer to alcohol in their Instagram stories and feed messages. Guided by the attention, retention, and motivation processes of social cognitive theory, we explore the occurrence and frequency of alcohol depictions, product centrality (background vs. foreground), the type of use (implicit vs. explicit), and behavioral incentives (positive vs. negative outcomes). Stories and feed messages from 120 SMIs were coded over a four-week period. Four conclusions were drawn. (1) The majority of SMIs share alcohol in their feed messages, and even more do so in stories. (2) SMIs depict a larger number of alcohol references in stories than in feed posts. This, however, reflects a general trend whereby SMIs use ephemeral messages more often to share any type of content. (3) SMIs showcase alcohol use in an attention-grabbing way, independent of the message type under consideration. They emphasize the positive outcomes related to alcohol use and foreground the beverages in half of their alcohol depictions. (4) Some alcohol depictions from SMIs contain a clear brand name or logo, potentially indicating that these references are commercially driven. However, these depictions oftentimes do not explicitly reveal a partnership with the alcohol industry. Based on the findings, practical guidelines for media literacy interventions and future research are formulated.

A STUDY OF DRUG UTILIZATION PATTERN OF ANALGESICS IN POST-OPERATIVE PATIENTS IN A TERTIARY CARE HOSPITAL

Objectives: The objective of the study was to evaluate the utilization pattern of analgesic use in post-operative wards of different surgical specialties. Methods: The study was observational and retrospective conducted, for 4 months from November 2022 to February 2023 in Tezpur Medical College, Assam and data were collected from 80 patients’ case sheets regarding analgesics prescribed during post-operative days, their route of administration, mono/combined therapy. Results: Non-steroidal anti-inflammatory medications (NSAIDs) as diclofenac (55.5%) and paracetamol (32.5%) were commonly prescribed for relief, both in monotherapy and combination therapy. Tramadol, an opioid was also used for severe pain relief and then shifted to NSAIDs. All patients were prescribed injectable analgesics on the day of surgery and the 1st post-operative day. Combination of aceclofenac + paracetamol (7.70%) was the most prescribed oral analgesic followed by tramadol + paracetamol (3.50%), mostly prescribed as brand names. Conclusion: Diclofenac was the most used NSAID in post-operative pain both in mono and combined therapy and the prescribing pattern was not rational related to more use of brand names.

Investigating the employment motivation, job satisfaction, and dissatisfaction of international high school teachers in China: the impact of the COVID-19 pandemic.

International education has become increasingly challenging to manage in an unpredictable world beset by pandemics, regional disputes, and evolving market practices. The last few decades have seen a huge demand for international education in China, and numerous acclaimed international brand names set up operations in China's K12 schooling sector. However, the COVID-19 pandemic exerted a noticeably negative impact on international high schools and their staff in China, and exacerbated a difficult period of management for these institutions. Interestingly, but perhaps unsurprisingly, the actual operation of these educational workplaces remains under investigated in academic studies. This paper therefore attempts to examine international high schools in China by focusing on their teachers and their associated employment motivation, job satisfaction, and dissatisfaction which has been perceptibly influenced by the impact of the COVID-19 pandemic. Through a qualitative, case-study approach which adopted semi-structured interviews, an acclaimed British high school, now closed, was investigated. The study found that international high school teachers were driven by diverse work motives such as the school's reputation, values, salary, environment, and chances for career development. Their job satisfaction was also multi-faceted, and their dissatisfaction in certain areas concerning. That is, they derived an early satisfaction from a range of facets, such as the students, class sizes, initial workloads, autonomy and collegiality. However, these early feelings were replaced by a sense of dissatisfaction and noticeable unhappiness resulting from leadership changes and subsequent management practices, increased workload, unmet employment package expectations and obligations, as well as limited professional development opportunities. This study highlights the importance of recruiting well, generating the right starting and longer-term conditions, retaining key staff and managing astutely. The work will be of interest to policy makers, investors, leaders, managers and staff alike. It will also extend educational research in the areas of teacher motivation, satisfaction and dissatisfaction, and in particular in China in international K12 settings.

(380) The Effect of Contemporary Oncologic Agents on Fertility Outcomes: A Review of the Literature

Abstract Introduction There is a growing number of referrals to urologists for oncofertility inquiries and concerns. Contemporary oncologic agents and their effect on fertility outcomes remain poorly understood. No study to date has evaluated the most common chemotherapeutic, immunologic, and targeted therapies seen by urologists and assessed their respective impacts on fertility. Objective We evaluated the effect of common contemporary chemotherapy, immunotherapy, and targeted therapy regimens on fertility outcomes. Methods We performed a single institutional review of all oncologic drugs taken by patients in the hematology/oncology clinic over the past five years (April, 2018- April, 2023). Agents were defined as contemporary if approval was received by the Food and Drug Administration 2006 or later. A review of the literature was conducted using PubMed to evaluate the effects on fertility for each drug. The MESH terms included agents [common name] OR [brand name] AND [sperm] OR [fertility] OR [infertility] OR [pregnancy] OR [birth] OR [reproductive] OR [reproduction] OR [ovarian] OR [testicular]. Search results for each agent were classified as “fertility impacted” or “fertility not impacted”. Studies were excluded if the primary aim or. secondary aim included fertility outcomes as a direct impact of chemotherapy, immunotherapy, or target therapy. Results We identified 75 patients who were treated with 28 unique contemporary oncologic agents. At least half of these agents demonstrated fertility inquiries in multiple patients referred. Agents with consultation >5 occasions included brentuximab (9), pembroluzimab (8), blinotumomab (8), pazopanib (6), and nivolumab (6). A total of 2,629 studies resulted from our search of which 56 studies met inclusion criteria determined by two independently blinded reviewers. Impact on fertility was defined as impaired spermatogenesis, reduced total sperm count/function, hypogonadism, impaired folliculogenesis or decreased ovarian reserve/function. Eight studies were conducted on animal models. Thirty-two studies reported an impact on fertility. Agents mostly commonly demonstrating fertility concerns included Melphalan (14), Ipilimumab (4), Pembrolizumab (3), Olaparib (2), and Trametinib (2). The most common drug classes affecting fertility outcomes included alkylating agents and immune checkpoint inhibitors. The majority of agents had only one study assessing fertility outcomes. At least a third of agents had literature to both support and oppose their impact on fertility. Conclusions Contemporary oncologic agents demonstrate significant variability in their impact on fertility. There is limited consensus on fertility outcomes amongst common oncologic agents referred to urologists for fertility workup. Evidence supporting negative fertility impacts is more commonly demonstrated among alkylating agents and immune checkpoint inhibitors. However, the available literature regarding the fertility impact of contemporary oncologic agents is limited and varied, reinforcing the need for provider familiarity and future research. Disclosure No.

Effectiveness of point-of-use (POU) filter system for removal of contaminants from water

Groundwater supplies most of the drinking water in the small settlements in the Danubian plain region of Bulgaria. The region is mostly agricultural, leading to chemical pollution, mostly with nitrogen, of the shallow groundwater. Direct health concerns, linked to nitrates contamination of water, determine the increased popularity of drinking water point-of-use (POU) filtration pitchers. The objective of this study was to evaluate the effectiveness of a commercial pitcher filtration system in removing select pollutants, such as metal ions, namely, copper and iron, nitrate nitrogen, and suspended solids (algal culture of Monoraphidium contortum) from augmented tap water. In addition, we have studied the effects on electrical conductivity and pH of water. The POU system of choice was a widely used brand name in Bulgaria, providing cartridges that fit most of the European pitcher filter brands. We have evaluated the performance of the filters at three different exploitation intervals – pre-washed new filter (0%), 50%, and 100% of the exploitation capacity set according to manufacturers’ claims of recommended volume of water, as well as at different contact times between the water and the filter media. The results indicate that the efficiency of the filters diminishes with aging and increases with increasing contact time – multiple filtrations.The efficiency in terms of electrical conductivity and amount of iron decreases proportionally with filter age, and in terms of phosphates, the maximum effect is observed in filters at 50% capacity. Water filtration reduced water conductivity by 12% in a single filtration and stabilized the pH values towards the neutral range. The effect on pH values is inversely proportional to the buffering capacity of the water. The filters removed 85–98% of copper ions and 20% of iron ions. Nitrate removal efficiency averages 40% and doubling the contact time increases the efficiency to 70%. The efficiency of removing suspended solids is on average 17%, mainly due to the small size of the particles.Overall, the POU systems are an effective way to purify water at home. The filter cartridges effectively reduce contaminants, such as metals and nitrates, which are particularly problematic in areas supplied by groundwater sources.

Новый взгляд на проблему заимствований: языковая фрустрация vs маркетинговые стратегии

The article reveals linguocognitive mechanisms as well as social reasons for active functioning of new borrowings in the modern public discourse and in commercial enterprises naming. The material for the analysis is a sample of the most frequent lexis in the micro synchrony that are not yet part of the host language lexicon, and comprises over one hundred and fifty lexical units, selected from the national corpus of the Russian language, public internet discourse, the author's collection of brand names (and names of businesses), radio and television programs. As a result of a comprehensive analysis, two main isomorphic types of borrowing functioning are identified. They are supposed to be motivated by multi-level linguistic, social, and pragmatic factors. Hence, the evidence of linguomental transformations of meaning is linked to the condition of linguistic frustration. This justifies considering it as a state of linguistic personality (at both the first and second levels, according to Yu.N. Karaulov), wherein the constraints of linguistic norms are lifted, and foreign-language word usage is motivated in specific speech act. A tendency of duplicate (native and foreign) naming in explicitly nominative and implicitly subjective-pragmatic functions has been established. It is suggested that the synergy of these functions conveys the speaker's subjective intentions and can be regarded as a marketing strategy of self-positioning in the act of foreign-language use in the nomination process, or as a commercial move, emphasizing the value of the product / service (i.e., commercialization of the nominative unit). Thus, the discourse becomes either status-oriented or conative. The linguistic phenomena under consideration introduce changes into the national concept sphere, as they contain features of a different language world view.

Analysis of drug list used in E Hospital in 2021

Objective: General analysis and analysis according to ABC/VEN of drugs list (DL) used at Hospital E (HE) from January 1, 2021 to December 31, 2021 by retrospective analysis. Research subjects and methods: Descriptive and retrospective study of all DL used at Hospital E from January 1 to December 31, 2021, drug use report of Hospital E in 2021 and related documents regarding DL of Hospital E from January 1 to December 31, 2021. Exploiting data at the Faculty of Pharmacy Hospital E, combined with exploiting the DL management software of the Faculty of Pharmacy, Hospital E in 2021. Results: The structure of DL HE in 2021 includes 566 drugs divided into 28 groups of pharmacological effects (PE), foreign drugs dominate over domestic drugs, single-component drugs account for a larger proportion, parenteral drugs, infusion predominates. According to ABC analysis: Group A accounted for 77.38% of value with 112 drugs divided into 19 groups of physical exercise. Group B accounted for 15.03% of value with 113 drugs divided into 22 groups PE. Group C accounted for 7.59% of value. According to VEN analysis: the vital drugs (V) have 105/566 drugs, accounting for 18.55% of the items. Essential drugs (E) have 401/566 drugs, accounting for 70.85% of items. Non-essential drugs (N) have 60/566 drugs, accounting for 10.60% of the items. According to the ABC/VEN matrix: The most important group (I): including AV, AE, AN, BV, CV: 35.87% items, 80.55% value. The important group (II): including BE, BN, CE: 58.65% items, 18.55% value. The less important group (III): CN: 5.48% items and 0.90% value. Key words: Drugs List (DL); Hospital E (HE); ABC/VEN matrix; Original brand name medicine (OBNM).

Biosimilars Would Reduce Health Care Costs But Are Yet Poorly Known - Patient Survey Study Among Biological Medicine Users.

From the beginning of the year 2024, gradually implemented amendment to the Medicines Act will enable interchange of biological medicines in pharmacies in Finland. The legislative change aims to reduce health care costs. Opinions of the biological medicine users regarding substitution in pharmacies and knowledge about biological medicines were determined by a patient survey in community pharmacies and via patient organizations in Finland. In total, 199 users of biological medicines responded to the survey. The respondents did not always know which product they were using, an originator or a biosimilar. This was more prominent among patients with biosimilars determined according to brand names. The more recently the biological medicine had been prescribed, the more likely a biosimilar was in use. Only about 40% of the respondents would enable pharmacies to substitute their biological medicine to a lower cost product. The most common obstacle to the idea of interchange in pharmacies was that the respondents wanted to keep the product the doctor had prescribed for them. In general, biosimilar users were more accepting towards possible interchange than originator users. Although the most recent treatments appear to be initiated with biosimilars, interchange in pharmacies could enable an efficient way to lower health care costs. However, guidance and awareness regarding biosimilars and biological medicines in general would improve patients' willingness towards the change, but also help pharmacists and prescribing doctors in their meaningful role.

A Taxonomy for Noninvasive Modes Provided by Portable Ventilators.

The purpose of this article is to identify (by brand name) and then classify the modes available on contemporary portable ventilators used for noninvasive ventilation in the United States. We propose a formal taxonomy that identifies the modes by their control variable, breath sequence, and targeting scheme, therefore describing what the mode does. Use of this taxonomy should be helpful in finding modes with comparable functionality that cater to the specific goal of mechanical ventilation and effective ventilatory strategies for each disease state.

Studi Kelayakan Bisnis Pada Brand Baju Muslim Sabhira_co

Fashion Sabhira is a business that grew from a reseller business to a distributor with a unique history. Sabhira was established on August 28, 2016 first operating as a reseller and distributor who takes goods from others. When the shop in Andir became very popular, Sabhira decided to open her own shop on Jln. Bengawan, Bandung. started to build its own brand with the name "Sabhira". The research method that we do is using a qualitative method by interviewing the company Sabhira_coShabira is a Brand Fashion business that is in demand by the Muslim community. The high demand in the market makes the opportunities of Sabhira's business very promising, both among women and men. The establishment of this Sabhira business will have a special impact on the economic structure of the community in the Sabhira business establishment environment, this can be seen from the increase in employee income. Where the average worker's income will increase with the salary he receives plus the bonuses given if the number of consumers who buy is more than the usual amount over time. Shabira is a Fashion Brand business that is in demand by the Muslim community. The high demand in the market makes the opportunities of Sabhira's business very promising, both among women and men. In the preparation of this business feasibility study report using 6 aspects.

Automating the Identification of Safety Events Involving Machine Learning-Enabled Medical Devices.

With growing use of machine learning (ML)-enabled medical devices by clinicians and consumers safety events involving these systems are emerging. Current analysis of safety events heavily relies on retrospective review by experts, which is time consuming and cost ineffective. This study develops automated text classifiers and evaluates their potential to identify rare ML safety events from the US FDA's MAUDE. Four stratified classifiers were evaluated using a real-world data distribution with different feature sets: report text; text and device brand name; text and generic device type; and all information combined. We found that stratified classifiers using the generic type of devices were the most effective technique when tested on both stratified (F1-score=85%) and external datasets (precision=100%). All true positives on the external dataset were consistently identified by the three stratified classifiers, indicating the ensemble results from them can be used directly to monitor ML events reported to MAUDE.

P835 Acceptability, feasibility, and adherence of an emulsifier-free diet in healthy volunteers

Abstract Background Emulsifiers are associated with intestinal inflammation and therefore excluded in new dietary strategies in inflammatory bowel diseases (IBD). We aimed to investigate the feasibility, acceptability, and adherence of an emulsifier-free diet (EFD) in healthy volunteers as part of the FOod Additives on the Mucosal barrier (FOAM) study. Methods We recruited 60 healthy volunteers to a 7-week interventional trial. After 1 baseline week of their habitual diet, participants followed an EFD for 6 weeks. Participants were instructed on how to follow an EFD yet were not advised on ultra-processed food (UPF) reduction. Every 2 weeks after starting the EFD (week 2, 4, and 6), subjects were asked about their experience on a 12-item questionnaire, including 5-point Likert scales, open-ended and multiple answer-type questions. Food logs were kept in the smartphone application 'Fatsecret', including photographs to capture brand names. Manual calculation of all days with plausible energy intakes (800-4200 kcals per day for men and 600-3500 kcals for women) for at least 79.5% of the time was performed to exclude incomplete reporting. Emulsifier intake was measured as number of servings of emulsifier-containing foods. Adherence rate was calculated as a percentage of mistake-free days. Results Of the 60 healthy volunteers, 2 were excluded due to NSAID use. Median (IQR) age was 25.5 years (23.0-33.0), median BMI was 22.7 kg/m2 (21.2-25.6) and 19.0% were male. Median percentage of plausible food logs was 100% (98.0-100%), and 1 subject was excluded due to inadequate dietary reporting. During the EFD, emulsifier intake significantly decreased (baseline vs week 1; p=2.3x10-9, vs week 6; p=5.3x10-9, Figure 1A), as well as UPF consumption according to the NOVA classification (baseline vs week 1; p=5.6x10-7, vs week 6; p=1.6x10-7, Friedman test with post-hoc paired Wilcoxon, Figure 1B). The adherence rate to the EFD was very high (median 88.1%, IQR 76.2-95.2%). Median number of mistakes during the EFD was 6 (2-14), for a median number of 3 selected food items (1-5). Most mistakes were made in the categories of dairy-like products, meat products, and bakery goods. The top 3 reported challenges included restricted food choices, checking food labels, and longer shopping times (Table 1). At week 6, For 70.7% the EFD was tasty to very tasty and for 72.4% it was acceptable to very acceptable. Hot meals and snacks were the most challenging meal types. Conclusion In this 7-week interventional trial in 60 healthy volunteers, adhering to an EFD was feasible and acceptable. While following the EFD, an inadvertent and stable decrease in UPF intake was noted. These finding represent important considerations when designing future dietary trials in IBD.

Place branding: Religion in shaping the three-dimensional essence of a city brand through stakeholder engagement.

This study explores the role of religion in engaging stakeholders in branding a place on social media and unmasks what implications this has for (re)constructing the three-dimensional meanings of a place brand. Using the content analysis method to examine the case of Saudi Arabia, it probes how the key stakeholder groups of the government and the residents structure and interact with the narratives of the cities-Jeddah and Riyadh-on Twitter, Facebook, and Instagram. The results show the Islamic religion serves as a powerful tool for motivating the residents to engage in the government-led city branding initiatives at the individual level. However, the strategy of dwelling on religion to mobilize resident engagement at the individual level towards the social level with the aim of growing resources in support of social development should be reassessed within a dynamic social system. Theoretically, the proposed framework of religion city branding expands the scope of stakeholder engagement in place branding research through the integration with the driver of religion, especially unveiling how religious factors shape the personality traits of a place brand. It contributes to the practical sense that religious elements might be deployed by the key stakeholder groups of the government and residents in city branding initiatives, which potentially contributes to their relationship and the engagement of residents in co-creating a place brand with the government. This Saudi-focused study, therefore, possesses significance for place branding practices in Middle Eastern countries and beyond.

Comparison of Ingredients and Allergens in Brand and Store Name Moisturizers.

Comparison of Ingredients and Allergens in Brand and Store Name Moisturizers.

Development of Pharmaceutical Equivalent Montelukast Sodium Immediate-Release, Film-Coated Tablets

Montelukast tablets are sold under the brand name Singulair and are used to control and prevent asthma symptoms. In this study, 10 mg film-coated montelukast tablets were developed as a generic drug in order to evaluate the pharmaceutical equivalent of the innovator’s products. The primary formulation ingredients used in all developed formulations (F1-F5) were the same as those described in the Singulair tablet package insert, except for formulations F3, F4, and F5, to which solubilizing enhancers were added to increase montelukast solubility. The core tablets were produced using the wet granulation method before being coated with HPMC polymer. FT-IR and DSC were used to determine drug and excipient compatibility. The micromeritic properties of the granules were assessed. The physicochemical properties of generated montelukast tablets and Singulair tablets were also investigated. The dissolution profiles of the tested drug and the innovator were assessed in a variety of pH mediums (pH 1.2, 4.5, 6.8, and water). The similarity (f2) and difference (f1) factors were computed. The accelerated and long-term stability of the tested drug in hot and humid climate zones was evaluated. The analytical method validation used in this study was ICH-acceptable for 8 parameters including specificity, range, linearity, accuracy, precision, limit of detection, limit of quantitation, and robustness. F1-F5 granules had similar properties, such as a pale-yellow color and excellent flow properties. There were no chemical interactions between montelukast and the excipients according to FT-IR and DSC analyses. The physical properties of all developed montelukast film-coated tablets were similar (average weight 212-218 mg; thickness 3.02-3.07 mm; assay 101-102% LA; disintegration time 3-4 min), except that the disintegration time of F3 was 8.10 min and that of F5 was 5.90 min, which was caused by the addition of poloxamer 188 to the formulation. In all mediums, only the F1 formula produced acceptable comparison dissolution profiles to Singulair. After 6 months of storage under accelerated and long-term conditions, the results showed the F1 formulation remained physically and chemically stable.

Study of Digital Marketing in Tourism and Hospitality Industry: A Literature Search Using the Keyword Co-Occurrence Mapping Network

Digital marketing is essential to the travel and hospitality industries. These days, it's a helpful tool for creating digital brand names and attracting and retaining clients. It has been demonstrated that using digital technology to implement marketing strategies, such as influencer marketing, social media marketing, and search engine optimization, benefits businesses. Through the process of monitoring customer behavior and assessing their preferences, digital marketing allows businesses to offer personalized and engaging content that encourages online referrals. Digital technology must be included into a number of sectors, including operations, services, communications, revenue management, distribution, and marketing, for the industry to be stimulated and reinvigorated. Hotel businesses need to reevaluate their current economic models and embrace digital marketing as an essential tool if they are to expand. The aim of the current research is to search the keywords in the database dimensions and creating co-occurrence mapping using VOSviewer software. Finally, the importance of digital marketing in tourism and hospitality industry is researched using research database and presented using term co-occurrence mappings.

Retrospective Analysis of Polyethylene Oxide and Polypropylene Oxide Block Copolymers Production and Industrial Applications (Review)

Introduction. Nowadays block copolymers of PEO and PPO (poloxamers, pluronics, proxanols) are among the most popular polymers in the pharmaceutical and biotechnological industries. They can be applied as effective nonionic surfactants, biological membrane stabilizers, elements of targeted delivery systems, solubilizers, as well as excipients in the technology of traditional dosage forms – gelling agents, lubricants, etc. For the past fifty years, the world's largest manufacturer of poloxamers has been the German chemical concern BASF. However, today in the Russian Federation there is a risk of defects, which defines the relevance of import substitution of this excipient.Text. The purpose of this review is to highlight the experience of production and implementation of PEO and PPO block copolymers into novel Russian scientists’ developments, comparing them with the experience of foreign research groups, which is necessary to assess the potential for import substitution. PEO and PPO block copolymers have been known in the Soviet Union since the late 60s as far as they are mentioned in textbooks of 1964 and 1973. Domestic block copolymers of PEO and PPO have been used in the oil refining industry, as well as in some branches of light industry and in the decontamination of radioactive waste. The unique domestic synthesis of PEO and PPO block copolymers was established in 1978 on the basis of the "Orgsintez" factory. Soviet poloxamers were produced under the brand name "proxanol" in a wide range of ratios of EO and PO units and molecular weights. It should be noted that today in the Russian Federation, industrial batches of the solubilizer Emuxol 268, which is close in its properties to the well-known poloxamer 188, are still produced, and block copolymers with other ratios of EO and PO units are synthesized to order.Conclusion. According to the retrospective analysis, the modern Russian industry has enough experience and resources to establish the synthesis of PEO and PPO block copolymers necessary to produce drugs and to develop innovative delivery systems and drugs. Based on the materials of the systematic review, the most complete register of known brands of PEO and PPO block copolymers synthesized over the past 50 years in our country and in the world was compiled for the first time, with a detailed description of their physicochemical properties.

Development of the lyrics-based deep learning algorithm for identifying alcohol-related words (LYDIA).

Music is an integral part of our lives and is often played in public places like restaurants. People exposed to music that contained alcohol-related lyrics in a bar scenario consumed significantly more alcohol than those exposed to music with less alcohol-related lyrics. Existing methods to quantify alcohol exposure in song lyrics have used manual annotation that is burdensome and time intensive. In this paper, we aim to build a deep learning algorithm (LYDIA) that can automatically detect and identify alcohol exposure and its context in song lyrics. We identified 673 potentially alcohol-related words including brand names, urban slang, and beverage names. We collected all the lyrics from the Billboard's top-100 songs from 1959 to 2020 (N = 6110). We developed an annotation tool to annotate both the alcohol-relation of the word (alcohol, non-alcohol, or unsure) and the context (positive, negative, or neutral) of the word in the song lyrics. LYDIA achieved an accuracy of 86.6% in identifying the alcohol-relation of the word, and 72.9% in identifying its context. LYDIA can distinguish with an accuracy of 97.24% between the words that have positive and negative relation to alcohol; and with an accuracy of 98.37% between the positive and negative context. LYDIA can automatically identify alcohol exposure and its context in song lyrics, which will allow for the swift analysis of future lyrics and can be used to help raise awareness about the amount of alcohol in music. Highlights Developed a deep learning algorithm (LYDIA) to identify alcohol words in songs. LYDIA achieved an accuracy of 86.6% in identifying alcohol-relation of the words. LYDIA's accuracy in identifying positive, negative, or neutral context was 72.9%. LYDIA can automatically provide evidence of alcohol in millions of songs. This can raise awareness of harms of listening to songs with alcohol words.