Branch Of Medicine Research Articles

Analysis of induced dynamic biceps EMG signal complexity using Markov transition networks.

Surface electromyography (sEMG) is a non-invasive technique to characterize muscle electrical activity. The analysis of sEMG signals under muscle fatigue play a crucial part in the branch of neurorehabilitation, sports medicine, biomechanics, and monitoring neuromuscular pathologies. In this work, a method to transform sEMG signals to complex networks under muscle fatigue conditions using Markov transition field (MTF) is proposed. The importance of normalization to a constant Maximum voluntary contraction (MVC) is also considered. For this, dynamic signals are recorded using two different experimental protocols one under constant load and another referenced to 50% MVC from Biceps brachii of 50 and 45 healthy subjects respectively. MTF is generated and network graph is constructed from preprocesses signals. Features such as average self-transition probability, average clustering coefficient and modularity are extracted. All the extracted features showed statistical significance for the recorded signals. It is found that during the transition from non-fatigue to fatigue, average clustering coefficient decreases while average self-transition probability and modularity increases. The results indicate higher degree of signal complexity during non-fatigue condition. Thus, the MTF approach may be used to indicate the complexity of sEMG signals. Although both datasets showed same trend in results, sEMG signals under 50% MVC exhibited higher separability for the features. The inter individual variations of the MTF features is found to be more for the signals recorded using constant load. The proposed study can be adopted to study the complex nature of muscles under various neuromuscular conditions.

Регенеративная медицина на экваторе женского здоровья и качества жизни: роль микрофрагментированной стромально-васкулярной фракции адипозной ткани в современной регенеративной медицине

Regenerative medicine remains the most rapidly growing and innovative branch of modern medicine. The key substrate of tissue regeneration is the stem cell, which has various differentiation pathways and is the source for various tissue morphotypes. In this regard, the medical community has asked a legitimate question about the potential of using stem cells for the treatment of various nosologies, including gynaecological ones. One of the most interesting, progressive and convenient methods of regenerative medicine is the use of microfragmented stromal-vascular fraction of autologous adipose tissue. On this basis, it is necessary to understand the molecular-biological features of this substance and evaluate its potential within the framework of correction of various gynaecological diseases.

A Discipline Like No Other: Marginalized Autonomy and Institutional Anchors in French Public Psychiatry (1945–2016)

Abstract Research on psychiatry in the United States has shown how, since the 1980s, the discipline has sought to increase its prestige and preserve its jurisdiction by embracing biomedical models of treatment and arguing it is a medical specialty like any other. While this strategy is consistent with what the literature on professions would expect, this paper analyzes an alternative case: French public psychiatry, which has remained in a position of marginalized autonomy, combining low status and economic precarity with state recognition of its specificity. Drawing on Bourdieu’s theory of fields, I analyze how the persistence of specialized psychiatric hospitals in France—most of which have closed in the United States—has shaped the conflict between psychiatrists favoring autonomy and actors in university hospitals and the Ministry of Health seeking to reduce it. These specialized hospitals have functioned as institutional anchors that contribute to maintaining the discipline’s autonomous position in the medical field in three ways: by socializing psychiatrists into viewing themselves as a distinctive branch of medicine, linking psychiatry to powerful actors in the state interested in maintaining the discipline’s distinctive role in social control, and concentrating a population of chronically ill persons not amenable to traditional medical interventions. This analysis expands on the literature on professionals and field theory by emphasizing the role of institutions in structuring the reorganization of jurisdictions and relationships between fields.

MedBench: A Large-Scale Chinese Benchmark for Evaluating Medical Large Language Models

The emergence of various medical large language models (LLMs) in the medical domain has highlighted the need for unified evaluation standards, as manual evaluation of LLMs proves to be time-consuming and labor-intensive. To address this issue, we introduce MedBench, a comprehensive benchmark for the Chinese medical domain, comprising 40,041 questions sourced from authentic examination exercises and medical reports of diverse branches of medicine. In particular, this benchmark is composed of four key components: the Chinese Medical Licensing Examination, the Resident Standardization Training Examination, the Doctor In-Charge Qualification Examination, and real-world clinic cases encompassing examinations, diagnoses, and treatments. MedBench replicates the educational progression and clinical practice experiences of doctors in Mainland China, thereby establish- ing itself as a credible benchmark for assessing the mastery of knowledge and reasoning abilities in medical language learning models. We perform extensive experiments and conduct an in-depth analysis from diverse perspectives, which culminate in the following findings: (1) Chinese medical LLMs underperform on this benchmark, highlighting the need for significant advances in clinical knowledge and diagnostic precision. (2) Several general-domain LLMs surprisingly possess considerable medical knowledge. These findings elucidate both the capabilities and limitations of LLMs within the context of MedBench, with the ultimate goal of aiding the medical research community.

Phytotherapeutic Approaches in Canine Pediatrics.

Phytotherapy is a clinical modality that incorporates botanical remedies as part of the therapeutic approach. It is a very ancient branch of medicine that is currently undergoing a renaissance, evident in the numerous preparations available on the market. The majority of these formulations are for preventive and curative use in adult animals. Experimental experiences in the pediatric age group are particularly scarce within the existing literature. Since these products are readily accessible, dog owners often turn to them due to their ease of availability, a preference for self-medication, and the perception that herbs are safer, gentler, and less expensive than conventional medications, often leading them to bypass seeking the advice of experienced professionals. The purpose of this review is to illustrate, on the basis of the currently available bibliography, phytotherapeutic approaches in canine pediatrics, paying particular attention to the adverse effects resulting from the use of certain plants, even when used in conjunction with some synthetic drugs. Consequently, it becomes evident that further clinical and more relevant studies, specifically focusing on puppies, are needed to increase knowledge about the effects of herbal remedies.

Pulsed Field Ablation and Neurocardiology: Inert to Efferents or Delayed Destruction?

The therapeutic use of irreversible electroporation in clinical cardiac laboratories, termed pulsed field ablation (PFA), is gaining pre-regulatory approval momentum among rhythm specialists for the mitigation of arrhythmogenic substrate without increased procedural risk. Though electroporation has been utilized in other branches of science and medicine for decades, apprehension regarding all the possible off-target complications of PFA have yet to be thoroughly identified and investigated. This brief review will summarize the preclinical and adult clinical data published to date on PFA's effects on the autonomic system that interplays closely with the cardiovascular system, termed the neurocardiovascular system. These data are contrasted with the findings of efferent destruction secondary to thermal cardiac ablation modalities, namely radiofrequency energy and liquid nitrogen-based cryoablation. In vitro neurocardiology findings, in vivo neurocardiology findings, and clinical neurocardiology findings to date nearly unanimously support the preservation of a critical mass of perineural structures and extracellular matrices to allow for long-term nervous regeneration in both cardiac and non-cardiac settings. Limited histopathologic data exist for neurocardiovascular outcomes post-PFA. Neuron damage is not only theoretically possible, but has been observed with irreversible electroporation, however regeneration is almost always concomitantly described.

Plant-derived nanovesicles offer a promising avenue for anti-aging interventions.

Over the past few years, the study of plant-derived nanovesicles (PDNVs) has emerged as a hot topic of discussion and research in the scientific community. This remarkable interest stems from their potential role in facilitating intercellular communication and their unique ability to deliver biologically active components, including proteins, lipids, and miRNAs, to recipient cells. This fascinating ability to act as a molecular courier has opened up an entirely new dimension in our understanding of plant biology. The field of research focusing on the potential applications of PDNVs is still in its nascent stages. However, it has already started gaining traction due to the growing interest in its possible use in various branches of biotechnology and medicine. Their unique properties and versatile applications offer promising future research and development prospects in these fields. Despite the significant progress in our understanding, many unanswered questions and mysteries surround the mechanisms by which PDNVs function and their potential applications. There is a dire need for further extensive research to elucidate these mechanisms and explore the full potential of these fascinating vesicles. As the technology at our disposal advances and our understanding of PDNVs deepens, it is beyond doubt that PDNVs will continue to be a subject of intense research in anti-aging therapeutics. This comprehensive review is designed to delve into the fascinating and multifaceted world of PDNV-based research, particularly focusing on how these nanovesicles can be applied to anti-aging therapeutics.

Veterinary Pathology Diseases and Disorders in Domestic and Wild Animals

Veterinary pathology plays a crucial role in understanding and managing diseases and disorders in both domestic and wild animals. This field encompasses the study of various pathologies, from infectious diseases like the Spanish Goat Encephalitis Virus, which causes severe neurological symptoms and high mortality in goats, to toxicological conditions such as oleander poisoning in horses, characterized by renal and cardiac lesions. It also includes the investigation of neoplastic conditions, as seen in canine apocrine gland adenocarcinoma of the anal sac and various tumors in African pygmy hedgehogs. The integration of clinical and histopathological findings is essential for accurate diagnosis, treatment, and management of these diverse conditions, highlighting the importance of veterinary pathology in animal health and welfare. Veterinary pathology, a vital branch of veterinary medicine, is instrumental in diagnosing, understanding, and managing a wide array of diseases and disorders in both domestic and wild animals. It encompasses the study of various pathologies, including infectious diseases, toxicological conditions, and neoplastic diseases. For instance, research into the Spanish Goat Encephalitis Virus sheds light on its neurological impact and high mortality rates in goats, while studies on oleander poisoning in horses focus on its renal and cardiac implications. Additionally, the field addresses neoplastic conditions such as canine apocrine gland adenocarcinoma of the anal sac and various tumors in African pygmy hedgehogs. This discipline is not only pivotal in diagnosing and treating these conditions but also plays a significant role in advancing our understanding of animal health and welfare, emphasizing the need for continuous research and collaboration between veterinary clinicians and pathologists.

Training interprofessional teams in geriatric emergency medicine: A modified team-based learning approach

BackgroundOlder adults deserve special healthcare provision in every branch of medicine. Turkey currently does not have geriatric emergency medicine (GEM) subspecialty training. Thus, interprofessional training for healthcare professionals involved in GEM services is required. Team-based learning (TBL) seems suitable to implement such training. We aimed to develop and implement a training program for healthcare professionals engaged with GEM services, and evaluate the program considering teacher and learner satisfaction and knowledge retention. MethodsThis was a design-based study in which a one-day GEM training program was developed based on the literature and expert opinions. The program was applied to 54 physicians, 98 nurses, 70 health officers, and 102 paramedics using a modified version of TBL. Teams included at least one representative from each profession. TBL was modified by adding a 1-h lecture and eliminating peer evaluation. Feedback forms, individual and group tests of TBL, and a retention test conducted six months later were used for program evaluation. ResultsThe mean group test score was higher than that of individual tests in all professions. Physicians’ individual test scores were higher than those of other professions, but this difference disappeared in the group test. The retention test mean score was higher than the individual test mean score but lower than that of the group test. Teacher and learner satisfaction was high. ConclusionWe implemented a training program using a modified TBL approach to teach GEM to relevant healthcare professionals; it yielded promising results regarding knowledge gain and retention, as well as teacher and learner satisfaction. The instruction design and method used in this study can be applied to multidisciplinary team training.

Prior-Guided Attribution of Deep Neural Networks for Obstetrics and Gynecology.

Obstetrics and gynecology (OB/GYN) are areas of medicine that specialize in the care of women during pregnancy and childbirth and in the diagnosis of diseases of the female reproductive system. Ultrasound scanning has become ubiquitous in these branches of medicine, as breast or fetal ultrasound images can lead the sonographer and guide him through his diagnosis. However, ultrasound scan images require a lot of resources to annotate and are often unavailable for training purposes because of confidentiality reasons, which explains why deep learning methods are still not as commonly used to solve OB/GYN tasks as in other computer vision tasks. In order to tackle this lack of data for training deep neural networks in this context, we propose Prior-Guided Attribution (PGA), a novel method that takes advantage of prior spatial information during training by guiding part of its attribution towards these salient areas. Furthermore, we introduce a novel prior allocation strategy method to take into account several spatial priors at the same time while providing the model enough degrees of liberty to learn relevant features by itself. The proposed method only uses the additional information during training, without needing it during inference. After validating the different elements of the method as well as its genericity on a facial analysis problem, we demonstrate that the proposed PGA method constantly outperforms existing baselines on two ultrasound imaging OB/GYN tasks: breast cancer detection and scan plane detection with segmentation prior maps.

ASSESSMENT OF LOCATION AND COURSE OF INFERIOR ALVEOLAR CANAL USING CONE BEAM COMPUTED TOMOGRAPHY

Background and Rationale:Forensic radiology is an evolving integral branch of forensic medicine. The most challenging tasks for forensic dentists and anthropologists has been identification and determination of sex of unknown human skeletal remains. Morphological and morphometric analysis of course and relationship with adjacent structures of mandibular canal can be useful in determining gender. CBCT being very useful in forensic contexts offering several advantages for postmortem forensic imaging including good resolution for skeletal imaging, relatively low cost, portability, and simplicity. Aim and objectives:To determine the sexual dimorphism of mandibular canal using cone beam computed tomography (CBCT) images. Materials and Methods:Course of mandibular canal classified into types based on considerable distance between the mandibular canal and the root apexes of premolars and molars, A) Catenary, B) Progressive descending, C) Straight. Location of mandibular canal was evaluated in 4 different points. Comparison of length and width of mandibular canal, prevalence of anterior loop, bifid mandibular canal, accessory mental and mandibular canal among genders. Comparison of continuous variables such as distance, length and width of canal with gender and side was done using unpaired t-test. Comparison of categorical variables with gender and side was performed using Chi-square test. The level of significant was 5%. Results:The prevalence of type of canal was highest in straight canals 53.9% followed by progressive descending and catenary canals 23.7% and 22.4% respectively. Measuring the length of canal showed statically significant result as mean length of IAC was 68.36 ± 5.24, 64.10 ± 3.18 in males and females respectively. Width and distance to adjacent structures had no significant result but dimensions were slightly lesser in females. Prevalence of anterior loop was found to be 57.9%.The most frequently observed type of bifid canal was retromolar42.9% followed by forward 28.6%, dental 19%and buccolingual 9.5%. There was no significant difference of assessing prevalence of anterior loop, accessory mental and mandibular foramen in relation to gender and side. Conclusion:Sex determination becomes one of the first priorities in the process of identification by a forensic investigator in the case of mishaps, chemical and nuclear bomb explosions, natural disasters, crime investigations, and ethnic studies.Advanced cross-sectional imaging modalities especially CBCT is a suitable tool for observing anatomic characteristics of mandibular canal in forensic odontology. In the current study we found significant result on type of course and length of canal for gender determination.

Cardiac blood vessels and irreversible electroporation: findings from pulsed field ablation.

The clinical use of irreversible electroporation in invasive cardiac laboratories, termed pulsed field ablation (PFA), is gaining early enthusiasm among electrophysiologists for the management of both atrial and ventricular arrhythmogenic substrates. Though electroporation is regularly employed in other branches of science and medicine, concerns regarding the acute and permanent vascular effects of PFA remain. This comprehensive review aims to summarize the preclinical and adult clinical data published to date on PFA's effects on pulmonary veins and coronary arteries. These data will be contrasted with the incidences of iatrogenic pulmonary vein stenosis and coronary artery injury secondary to thermal cardiac ablation modalities, namely radiofrequency energy, laser energy, and liquid nitrogen-based cryoablation.

The Opinions and Working Experiences of Doctors from Different Branches of Medicine Working in Turkey Concerning Speech and Language Pathologists

Objective: This study aimed to examine the thoughts, knowledge, collaborative processes, and experiences of doctors in different branches of medicine, as these comprise the occupational groups in which speech-language pathologists/therapists (SLPs) work in interdisciplinary and multidisciplinary capacities. 
 Material and Method: A Google survey was created focusing on the opinions about and working experiences of doctors in different branches of medicine working in Turkey with SLPs. The questionnaire consisted of 18 questions and four parts. 
 Results: The study was conducted with 116 doctors, 28.4% of whom were neurologists, 28.4% were otorhinolaryngologists, 21.6% were pediatricians, and 21.6% were other specialists. Only 25.9% (n=30) have worked with an SLP before. Speech sound disorders, fluent speech disorders, and developmental language disorders were the most frequently chosen SLP study areas among all the specialties in which doctors in all branches of medicine work. The lowest number of doctors chose swallowing disorders, followed by cognitive communication disorders and X-linked language disorders, as the field of work of SLPs. 
 Conclusion: It was found that the number of SLPs working in doctors' institutions, the level of cooperation between doctors and SLPs, and doctors' knowledge about the working areas of SLPs were low. It has been observed that physicians' awareness, especially in swallowing and cognitive communication disorders, is lacking. A strong partnership between physicians and SLPs is vital for appropriate service delivery to patients. For this reason, the number of SLPs working in institutions should be increased, as should the level of knowledge among doctors in different branches of medicine concerning SLPs’ services.

The role of general surgery consultations on patient diagnosis and treatment in the Tertiary Medical Center

Background: The field of general surgery is an important one in medicine. It includes the systems and organs connected to practically every bodily part. Because of this, general surgery is frequently requested for consultation and has a significant role in emergency service applications. The study’s objective is to evaluate general surgery consultations based on their specific attributes. Methods: A retrospective analysis was performed on 814 patients who were consulted at our hospital’s general surgery clinic between January and June 2021. The departments requesting consultation, the reasons for the consultation, the examinations requested before and after the consultation, and the decisions made after the consultation were evaluated. Results: The department that required the most consultation from the general surgery branch was the emergency department with 91.5% the most common reason for consultation is nonspecific abdominal pain with 18.1% has been seen. General surgery consultation in patients presenting with abdominal specific complaints, previously ultrasonography and computed tomography were requested in 88.6% of patients. Conclusion: The fact that physicians request unnecessary consultations and resort to advanced imaging examinations with the reservation of malpractice leads to an increase in both cost and intensity for the health system. Requesting a consultation in conditions where it is more necessary will relieve the intensity of the health system.

Breakthroughs in Oral and Maxillofacial Surgery

In the field of oral and maxillofacial surgery, continuous advances have ushered in a new era of innovation, profoundly influencing this branch of medicine [...]

Opportunities and Challenges in Catheter-Based Irreversible Electroporation for Ventricular Tachycardia.

The use of catheter-based irreversible electroporation in clinical cardiac laboratories, termed pulsed-field ablation (PFA), is gaining international momentum among cardiac electrophysiology proceduralists for the non-thermal management of both atrial and ventricular tachyrhythmogenic substrates. One area of potential application for PFA is in the mitigation of ventricular tachycardia (VT) risk in the setting of ischemia-mediated myocardial fibrosis, as evidenced by recently published clinical case reports. The efficacy of tissue electroporation has been documented in other branches of science and medicine; however, ventricular PFA's potential advantages and pitfalls are less understood. This comprehensive review will briefly summarize the pathophysiological mechanisms underlying VT and then summarize the pre-clinical and adult clinical data published to date on PFA's effectiveness in treating monomorphic VT. These data will be contrasted with the effectiveness ascribed to thermal cardiac ablation modalities to treat VT, namely radiofrequency energy and liquid nitrogen-based cryoablation.

Chinese experts' consensus on the application of intensive care big data.

The development of intensive care medicine is inseparable from the diversified monitoring data. Intensive care medicine has been closely integrated with data since its birth. Critical care research requires an integrative approach that embraces the complexity of critical illness and the computational technology and algorithms that can make it possible. Considering the need of standardization of application of big data in intensive care, Intensive Care Medicine Branch of China Health Information and Health Care Big Data Society, Standard Committee has convened expert group, secretary group and the external audit expert group to formulate Chinese Experts' Consensus on the Application of Intensive Care Big Data (2022). This consensus makes 29 recommendations on the following five parts: Concept of intensive care big data, Important scientific issues, Standards and principles of database, Methodology in solving big data problems, Clinical application and safety consideration of intensive care big data. The consensus group believes this consensus is the starting step of application big data in the field of intensive care. More explorations and big data based retrospective research should be carried out in order to enhance safety and reliability of big data based models of critical care field.

Determinants of Postgraduate Medical Education Regarding Speciality and Place among North Indian Graduates: A Cross Sectional Study

Background: Medical undergraduates are a vital source of the country’s physicians. Their preference for medicalspecialties helps allocate the workforce among various medical specialties. The options for medical careerspecialties have increased, parallel to expanding knowledge in different fields. Given the vast opportunities tochoose from, the factors influencing the choices of medical interns in our country need to be better understood.Objectives: This study was conducted to know what factors influence the interns to choose the place to pursuepostgraduation.Methods: This cross-sectional study was conducted from July 2022 to August 2022 at GMC Patiala. Out of the 203interns of the MBBS batch 2017 batch, 199 were interviewed using an online google form.Results: Out of the 199 participants, 73.8% of students wanted to pursue postgraduation in India. General Medicine(77.4%) was the most preferred branch. Almost half (47.7%) of students chose the specialty during their internship.Most participants (82%) with a family income of fewer than ten lakhs preferred to pursue Postgraduation in India.Conclusions: Participants favored clinical medicine branches, with General Medicine being the most popular.Family income, rather than marks, influenced the decision to pursue postgraduate studies abroad or in India. Themain reason for studying abroad was better education and a higher standard of living. At the same time, somestudents preferred to stay close to home and study in India for postgraduate studies for the sake of family andfamiliar surroundings.

Determinants of Postgraduate Medical Education Regarding Speciality and Place among North Indian Graduates: A Cross Sectional Study

Background: Medical undergraduates are a vital source of the country’s physicians. Their preference for medicalspecialties helps allocate the workforce among various medical specialties. The options for medical careerspecialties have increased, parallel to expanding knowledge in different fields. Given the vast opportunities tochoose from, the factors influencing the choices of medical interns in our country need to be better understood.Objectives: This study was conducted to know what factors influence the interns to choose the place to pursuepostgraduation.Methods: This cross-sectional study was conducted from July 2022 to August 2022 at GMC Patiala. Out of the 203interns of the MBBS batch 2017 batch, 199 were interviewed using an online google form.Results: Out of the 199 participants, 73.8% of students wanted to pursue postgraduation in India. General Medicine(77.4%) was the most preferred branch. Almost half (47.7%) of students chose the specialty during their internship.Most participants (82%) with a family income of fewer than ten lakhs preferred to pursue Postgraduation in India.Conclusions: Participants favored clinical medicine branches, with General Medicine being the most popular.Family income, rather than marks, influenced the decision to pursue postgraduate studies abroad or in India. Themain reason for studying abroad was better education and a higher standard of living. At the same time, somestudents preferred to stay close to home and study in India for postgraduate studies for the sake of family andfamiliar surroundings.

Современные тренды эстетической гинекологии

Aim. To conduct a systematic analysis of the data available in modern literature on modern methods used in aesthetic gynecology. Key points. In the world of modern medicine and cosmetology, new methods and technologies are constantly appearing, aimed at improving the quality of life and well-being of patients. A new branch of medicine – aesthetic gynecology – is gaining great popularity. This review examines its current areas: plastic surgery and thread lifting, injection methods (use of fillers and PRP, carbon dioxide, autologous fat), laser and radio wave technologies, and the use of high-intensity focused ultrasound (HUFU). Conclusion. Modern methods of aesthetic gynecology, based on the latest scientific achievements, make it possible to solve many medical problems associated with disorders of the urogenital tract. As this field evolves, one of the most important issues is the development of standardized procedures for safe practice. Long-term studies are required to establish the results of these methods and confirm the effectiveness of new approaches in the field of aesthetic gynecology. Key words: fillers, laser technologies, thread lifting, HUFU.