Brachytherapy In Europe Research Articles

226 Patterns of Care for Brachytherapy in Europe (PCBE)

226 Patterns of Care for Brachytherapy in Europe (PCBE)

1 Patterns of care for brachytherapy in Europe (PCBE)

1 Patterns of care for brachytherapy in Europe (PCBE)

3 oral + poster Patterns of care for brachytherapy in Europe (PCBE): results in Spain

3 oral + poster Patterns of care for brachytherapy in Europe (PCBE): results in Spain

Radioactive stents: problems and potential solutions

The implantation of radioactive stents was the first procedure of a coronary brachytherapy in Europe examined in multicenter clinical trials. After more than 400 patients with radioactive stents were analyzed, it became clear that overall restenosis rates were not reduced. A new phenomenon called the "edge effect" or "candy-wrapper" effect was discovered, which later was also described for catheter-based brachytherapy. Currently, the implantation of radioactive stents for the prevention of restenosis cannot be recommended. Although technical improvements of radioactive stents are theoretically possible, novel drug coated stents may overcome any future research of stent-based radiotherapy. Drug eluting stents induce antiproliferative effects beyond the stent margins. Edge effects were not observed in preliminary trials. However, long-term results need to be awaited.