Transitional Flow Research Articles

Centrifugal through-flow rotor-stator cavity boundary layer transition based on the effect of roughness

In this study, we report a set of compressible Reynolds-averaged Navier–Stokes simulation results of rotor-stator cavity flows under a range of conditions such as surface roughness, Reynolds number, and through-flow coefficient. The main objective is to determine the effect of rotor roughness on the characteristics of the fluid and thermal boundary layers. The boundary layer inside the disk cavity is found to be Batchelor-type within the present parameter range. Increases in Reynolds number, through-flow coefficient, and surface roughness all enhance the flow circulation inside the disk cavity. The thickness of the Ekman layer on the rotor is almost twice that of the stator Bodewadt layer. Rotor roughness significantly affects the turbulent characteristics of the flow when the rotor-stator cavity is rotationally dominated, but the effect is small when the cavity is through-flow dominated. Increasing rotor roughness accelerates the separation of the stator boundary layer, particularly at weak through-flow. On heat transfer, large rotor roughness induces an overall temperature rise in the cavity and reduces the thermal boundary layer thickness. The effects are more pronounced at low Reynolds numbers and small through-flow coefficient. The present results can facilitate the design of high-efficiency rotor-stator cavities.

Investigation on transition characteristics of hydrofoil boundary layer based on algebraic local-correlation-based transition modeling model

Hydrofoil shapes are used for the marine turbine blades to capture kinetic energy from water currents effectively. Predicting transitions is a critical concern when studying the hydrofoil boundary layer. This paper analyzed the transitional behavior of the boundary layer in the National Advisory Committee of Aeronautics (NACA) hydrofoil, NACA0009, with a blunt trailing edge using the Algebraic Local-Correlation-based Transition Modeling (Algebraic LCTM) model. First, through sensitivity analysis, the effects of the maximum y+ (the dimensionless distance y to the wall), grid expansion ratio, number of normal and streamlined grids, and timescale on transition prediction were studied. The results indicate that finer y+ value and appropriate grid expansion ratios can improve the accuracy of transition prediction, while the influence of timescale on the prediction results is relatively small within the range of Courant number theory values. Second, further analysis was conducted on the transition prediction performance under different Reynolds numbers. It was found that the model predictions were consistent with experimental values at low Reynolds numbers, but the predicted transition position was advanced at high Reynolds numbers, mainly because of the significant disparity in eddy viscosity coefficients within the free flow field. In the study of leading-edge roughness bands' impact on boundary layer transition for hydrofoil, the introduction of roughness significantly expedited the transition process. The Algebraic LCTM model outperformed the gamma (γ) transition model, reducing prediction errors by 5–40% for boundary layer parameters and maintaining errors between 0.005 and 4% for wake vortex shedding frequency, as opposed to the γ model's 0–23%. The results of this study provide a theoretical basis for hydrofoil design.

Local-Variable-Based Transition Model for Hypersonic Flows Considering Wall Mass Injection

Pyrolysis gas injection during the ablation process will affect the hypersonic boundary-layer transition. This paper proposes a three-equation γ-Reθ-fb transition model that considers wall mass injection. First, the boundary conditions of wall mass injection are established and verified. Second, based on analysis of the compressible boundary-layer solutions under wall mass injection, new transition correlations are developed. This allows an injection factor transport equation to be constructed using strictly local variables, and this equation is coupled with the γ-Reθ transition model. Additionally, to model the wall mass injection effects in the fully turbulent zone, the wall boundary conditions for the specific turbulence dissipation rate are amended. The results of numerical simulations show that the transition onset locations and the changes in the heat transfer rate are reasonably consistent with experimental data.

Three-dimensional nonlinear vortex-induced vibrations of risers under internal gas-liquid and external shear flows

A novel three-dimensional (3D) dynamic model is proposed to explore the nonlinear vortex-induced vibration (VIV) characteristics of top-tension risers under the combined action of internal gas-liquid two-phase flow and external shear flow. The van der Pol equation is used to evaluate the interaction between the riser and the external shear flow. The nonlinear governing equations are established through Hamilton's principle, and they are discretized by the Galerkin method and solved via the Runge-Kutta method. The VIV responses calculated by the proposed nonlinear dynamic model are compared with the previously experimental and computational fluid dynamics (CFD) results, demonstrating the effectiveness and accuracy of the present theoretical method. The influences of the internal flow effect, the tension and the shear parameter of the external flow on the VIV responses of the riser are analyzed. The results show that when the internal flow effect is not considered, the transition of the external flow from uniform flow to shear flow leads to an increase in excited modes and a decrease in resonance responses of the riser in the cross-flow (CF) direction. Furthermore, with the increase of the external shear flow velocity, resonances at different positions of the riser are not synchronized, which is different from that of the riser in uniform flow. In the case of the riser conveying gas-liquid two-phase flow and being subjected to external uniform or shear flow, the increase in the velocity of the liquid phase leads to an increase in the maximum response amplitudes of the riser in the in-line (IL) and axial directions. When the internal flow changes from single-phase to gas-liquid two-phase, the maximum VIV responses of the riser in the IL and axial directions tend to decrease regardless of whether the riser is in uniform flow or shear flow.

Interaction of second-mode instability and distributed roughness elements in the hypersonic boundary layer over a sharp cone

The ablation of the thermal protection system (TPS) on the aircraft surface generates distributed roughness elements (DRE), which is expected to affect the hypersonic boundary-layer instability seriously. This work presents the experimental investigation of hypersonic boundary-layer instability waves on a 7° half-angle sharp cone with DRE allocated downstream of synchronization point at 0° angle of attack using surface flush-mounted pressure sensors, focused laser differential interferometer (FLDI), infrared thermography and schlieren technique. The experimental results showed that when the DRE (lower than the local boundary-layer height) was located downstream of the synchronization point, the Mack second mode still dominate the boundary-layer instability, and the transition onset was not significantly affected by DRE at various Reynolds numbers. Based on further analysis in the region downstream of roughness, the DRE didn't influence the nonlinear interaction among instability waves materially, although it promoted the growth of instability waves compared with the smooth case. However, the nonlinear interactions were decaying adjacent to the DRE, as the Mack second-mode instability waves cannot penetrate into the separation bubble because of the flow separation induced by the DRE. The FLDI measurement along the wall-normal direction revealed the second-mode instability waves were suppressed close to the wall by the complex roughness surface at the DRE region, and also confirmed the existence of second-mode instability waves at these streamwise locations. The evolution of instability waves followed the linear stability theory (LST), despite the existence of complex wall surfaces. This work enriches the understanding of the effect of DRE on hypersonic boundary-layer transition and demonstrates the spatial characteristics of instability waves above the complex surface.

Mixed material point method formulation, stabilization, and validation for a unified analysis of free-surface and seepage flow

This paper presents a novel stabilized mixed material point method (MPM) designed for the unified modeling of free-surface and seepage flow. The unified formulation integrates the Navier-Stokes equation with the Darcy-Brinkman-Forchheimer equation, effectively capturing flows in both non-porous and porous domains. In contrast to the conventional Eulerian computational fluid dynamics (CFD) solver, which solves the velocity and pressure fields as unknown variables, the proposed method employs a monolithic displacement-pressure formulation adopted from the mixed-form updated-Lagrangian finite element method (FEM). To satisfy the discrete inf-sup stability condition, a stabilization strategy based on the variational multiscale method (VMS) is derived and integrated into the proposed formulation. Another distinctive feature is the implementation of blurred interfaces, which facilitate a seamless and stable transition of flows between free and porous domains, as well as across two distinct porous media. The efficacy of the proposed formulation is verified and validated through several benchmark cases in 1D, 2D, and 3D scenarios. Conducted numerical examples demonstrate enhanced accuracy and stability compared to analytical, experimental, and other numerical solutions.

Correlation effect between the capillary flow and evaporation rate of water in a 2-D photothermal membrane

To shed light on the correlation effect between the capillary flow and phase transition of water in photothermal evaporation, the non-equilibrium molecular dynamics (NEMD) simulations were employed to investigate the evaporation of water in Multilayered graphene oxide membranes. It was initially found that water molecules need to overcome strong energy barriers to migrate upward by layers before evaporation, with the energy barrier increasing with the reduction in nanogap, hydroxyl content, or increase in layer spacing of graphene sheets. The strong energy barrier accordingly results in dramatic sensible heat conversion and high evaporation temperature. It was shown that the enhanced temperature and hydrophilicity both weaken the hydrogen bond strength of water molecules confined in 2-dimensional channels, contributing to the reduced evaporation enthalpy. The preferential pathways in graphene channels or the weakened hydrogen bonds in hydroxyl-functionalized graphene of water molecules were found to be important influences on capillary flow energy consumption, leading to differences in evaporation energy supply. In combination with these effects, the evaporation rate could be increased by up to 2 folds and an interfacial enthalpy of evaporation below 1500 kJ kg−1 could be achieved by properly tuning the configuration and chemical properties of the graphene membrane. Our findings lay a theoretical foundation for providing a strategy to improve the interfacial evaporation performance in desalination.

Flow Structure and Periodic Processes in a Disc-Shaped Vortex Chamber of a Hydrodynamic Cavitator

Introduction. The essence of the acoustic – cavitation processes is that the liquid is passed through sound with a pressure at the wave surface of more than 3 bar that causes local breaks of the liquid in the vacuum phase of the wave and the collapse in the manometric phase. The opposite walls of each cavern in the collapse approach at a speed exceeding two speed of sound, due to which a high energy density is achieved at the meeting point, and what is especially valuable is the mutual transitions of energies from one form to another, unattainable under normal conditions, and, moreover, as inside cavitation area and near it. The novelty of the work is confirmed by the results of a periodic information and patent analysis, and by four patents received for inventions on the topic under consideration.Aim of the Study. The study is aimed at improving the acoustic-cavitation qualities of a disk-shaped vortex chamber used as a liquid whistle.Materials and Methods. In the study, there were used numerical modeling of flows in the FlowVision program, experimental determination of flow rates using a pitot tube, film method, removal of frequency response using SpectraPLUS 5.0, and visualization of flows and processes on optically transparent devices by the method of color indicators in stroboscopic lighting high-speed video shooting.Results. The mechanism of sound generation and noise in the flow transiting through the device has been found. The corrective effect of pump pulsations f = 300 Hz on the sound generation mechanism was revealed. The disc-shaped character of the device, which encloses the input flow in cross section from three directions, contributes to creating a more expressive acoustic signal, forming two conjugate torus vortices along the shell that ensures uniformity of the circumferential flow, attenuation of longitudinal high-frequency oscillations f = 200 kHz, and the creation of periodic zones of increased pressure along the shell. The concentrated tangential entrance to the device determines the central asymmetry of the flows in it and a number of processes that create acoustic noise.Discussion and Conclusion. The frequency of the useful acoustic signal in the vortex chamber is proportional to the speed of the transit flow, and the amplitude is proportional to the dimensions of the device. Along with the useful signal created by the interaction of the peripheral and input parts of the transit flow, noise of similar frequencies is created in the device. Other sources of noise generation are due to the presence of a concentrated tangential input. The formation of two conjugate torus vortices along the shell can be used as a means of controlling the process of interaction between parts of the transit flow. The disc-shaped vortex chamber combines the functions of sound generation and the ability to create a centrifugal field, which expands its technological capabilities.

Numerical appraisal of the role of heat transfer regimes on transient response of carbon dioxide based supercritical natural circulation loop during power upsurge

Appearance of steep property gradients with change in temperature is a fascinating feature of any supercritical fluid, which can instigate intricate dynamics in supercritical natural circulation loops by modulating the effective forces. While most of the relevant literature focuses on stability evaluation, anticipation regarding the transient response of the system during power transition is of utmost significance, especially in high-power applications. Present study aims at furnishing insight on the same by developing a one-dimensional numerical model of a rectangular loop with supercritical CO2 as the working medium, and characterizing the temporal trends over a wide range of heating power. Two different profiles of power upsurge have been tested for different regimes of heat transfer, unearthing intriguing characteristics. The combination of initial and final regimes during any transformation is found to be the most crucial factor. Single-step rise in power, in general, is the most vulnerable one, specifically during large-scale change of the order of 1000 W, and better be employed only at low-power regime. Even single-step change ∼ 25 W can inflict instability and flow transition within the transition regime. Power transformation following linear ramp profile with transition periods of 5, 10 and 20 s is identified to be the most suitable one across all the regimes. It can successfully mitigate instability even in the later parts of the transition regime, albeit at the expense of greater time requirement to attain the final stable state and possibly a greater period of transformation. Change through multiple small steps (about 250 W for large change in low power regime and 15 W within transition regime) can also be a feasible option for avoiding the growth of unstable oscillations at higher powers.

Coupled Wall Boiling and Population Balance Model for High Void Fraction Flows Under Sub-Cooled Nucleate Boiling Regime: Model Development and Validation

Abstract The subcooled flow boiling of water in a vertical annulus channel is studied numerically at low-pressure conditions. The two-fluid model is developed with flow-regime dependent interfacial transfers for mass, momentum, and energy using the algebraic interfacial area density (AIAD) framework. A discrete population balance model is used to mechanistically determine the vapor bubble diameter in the flow channel by considering the bubble aggregation and breakup effects. Energy balance at the heated wall for the subcooled nucleate boiling is handled using a suitable wall boiling model. A coupling is achieved between the discrete population balance and the wall boiling model for the nucleation and the growth rate of the vapor bubbles along the heated wall. The developed model simulates the reference experimental cases of flow boiling in a vertical channel for various flow and thermal conditions. At low wall heat flux, the wall boiling generates vapor bubbles near the heated wall and within the bubbly flow regime. With an increase in the wall heat flux, the aggregation and evaporation cause the formation of larger bubbles, which progress toward the flow channel core region, a phase that is representative of the transitional flow regime. The model's capability to predict such flow regime transition is validated with the experimental results. The bubble aggregation is found to be dominant compared to the breakup, and thus, proper choice of the aggregation factor is important for the accurate prediction of vapor parameters for the subcooled flow boiling at low-pressure conditions.

Tailored directional porosity in ceramic matrix composites (CMCs) for hypersonic applications

AbstractIn the field of hypersonic systems and their missions, the occurring flows impose extreme mechanical and thermal loads on the materials used. At the German Aerospace Center (DLR), extensive research is conducted in this area, ranging from design and specification to the development of suitable materials concluding with the proof of concept under realistic conditions in wind tunnels. In recent years, ceramic matrix composites (CMCs) have been investigated for specific aspects of hypersonics. These materials exhibit consistent mechanical behavior over a wide temperature range (up to 1600 °C), coupled with high damage tolerance and thermal shock resistance, distinguishing them from metals and superalloys. Particularly, special porous C/C–SiC ceramics (carbon-fiber-reinforced carbon with silicon carbide) enable innovative material applications for components in transpiration cooling, fuel injection, or boundary-layer transition control. The work presented focuses on the next generation of porous C/C–SiC ceramics currently in development. By deliberately modifying the textile preform, the resulting microstructure and pore morphology are influenced, allowing for control over both the total volume and the orientation of the pores. Relevant parameters influencing porosity have been determined based on the results, and an initial characterization has been conducted. It has been demonstrated that there is a preferred direction of porosity within the sample thickness (Z-axis), and in terms of hypersonic-relevant properties, an absorption coefficient of 0.58 for an acoustic wave at 500 kHz (static pressure of 15 kPa), as well as a length-specific flow resistance of 3.4 MPa s/m2 and an overall porosity of 12.25% were determined. Building upon these promising initial findings, the goal is to further expand the understanding of the parameters influencing porosity and to generate a tailored material for different application scenarios by correlating them with hypersonic properties.

Determinants of cerebral blood flow and arterial transit time in healthy older adults.

Cerebral blood flow (CBF) and arterial transit time (ATT), markers of brain vascular health, worsen with age. The primary aim of this cross-sectional study was to identify modifiable determinants of CBF and ATT in healthy older adults (n = 78, aged 60-81 years). Associations between cardiorespiratory fitness and CBF or ATT were of particular interest because the impact of cardiorespiratory fitness is not clear within existing literature. Secondly, this study assessed whether CBF or ATT relate to cognitive function in older adults. Multiple post-labelling delay pseudo-continuous arterial spin labelling estimated resting CBF and ATT in grey matter. Results from multiple linear regressions found higher BMI was associated with lower global CBF (β = -0.35, P = 0.008) and a longer global ATT (β = 0.30, P = 0.017), global ATT lengthened with increasing age (β = 0.43, P = 0.004), and higher cardiorespiratory fitness was associated with longer ATT in parietal (β = 0.44, P = 0.004) and occipital (β = 0.45, P = 0.003) regions. Global or regional CBF or ATT were not associated with processing speed, working memory, or attention. In conclusion, preventing excessive weight gain may help attenuate age-related declines in brain vascular health. ATT may be more sensitive to age-related decline than CBF, and therefore useful for early detection and management of cerebrovascular impairment. Finally, cardiorespiratory fitness appears to have little effect on CBF but may induce longer ATT in specific regions.

Tri-functional carbon membrane for one-step uptake of low-concentration hydrogen to high purity

The uptake of hydrogen (H2) from natural gas pipelines (CH4) through membrane separation technology is an efficient avenue of obtaining H2 resources. Carbon membranes have the potential to be an attractive option for energy-efficient gas separations in the next generation of membranes due to their precise molecular discrimination ability and easy scalability. Here, we report a carbon membrane composed of a mesoporous substrate, seed layer and sieving layer, achieving a one-step uptake with 55.3 × 10-9 mol·m−2·s−1 Pa−1 permeance and a separation factor for H2/CH4 of 359.1 by feeding hydrogen (20 vol%). As revealed by the kinetic diffusion experiment, H2 is transported in mesoporous substrate via Knudsen flow, differing from the transition flow taken by CH4, thus H2 diffusion rates exceed CH4 by an order of magnitude, which substantially increased H2 purity from 20 vol% to higher purity as gas mixtures passed through the substrate. Then, the H2 passed through the seed layer and sieving layer, resulting in a final H2 purity of ∼ 99 vol%, a sharp increase from the initial low concentration. This carbon membrane integrates three functions of capture, pre-separation and purification into one material and provides a new solution for the uptake of H2 from CH4.

Aerodynamics of a three-dimensionally deformed rigid wing

A flexible wing with a large aspect ratio emerges in many modern engineering applications (e.g. solar planes and super large wind turbine blades) and its interaction with incident flow differs markedly from conventional fluid–structure interactions (FSI), exhibiting frequently a large three-dimensional (3D) deformation. Yet, there is little information on how such deformation may change wing aerodynamics. This work investigates the aerodynamic performance of deformed and cantilever-supported NACA0012 rigid wings with an aspect ratio of 9, using ANSYS Fluent with the SST-κ-ω turbulence model at a chord-length-based Reynolds number Rec of 1.5 × 105. Numerical simulation is validated experimentally. The wing tip bending displacement is up to 4.14c, and the maximum twisted angle is up to 7°. The angle α of attack varies from 0° to 20° at mid span of the wing. It has been found that the torsional deformation can significantly advance the local flow separation, reattachment, bubble length, and transition from laminar to turbulence, resulting in a drop in the critical angle αcr of attack, at which the separation bubble size reaches the maximum. Accordingly, the lift and drag coefficients increase, as well as the bending and pitching-up moments, though the stall is advanced due to a change in local α. The tip vortex is also enhanced, inducing strong downwash postponing the separation bubble on the wing and resulting in redistributed force near the wing tip that increases markedly the local bending moment but decrease the local pitching-up moment. On the other hand, the bending deformation tends to produce an effect opposite to the torsion on the flow structure and causing little change in the lift coefficient, though reducing the induced drag and moments appreciably. With both deformations in place, the torsion overwhelms the bending in general in terms of its impact upon aerodynamics and flow structures, the latter acting to cancel at least partially the effect of the former.

Regenerative Orr mechanism yielding large non-modal perturbation energy growth in a viscosity stratified plane shear flow

Transiently growing non-modal perturbations can play a crucial role in the transition of plane shear flows in modally stable regimes. In terms of the extent of transient amplification, three-dimensional perturbations are typically more prominent due to the lift-up effect. In contrast, two-dimensional (2D) spanwise-independent perturbations are often considered less important as they typically undergo modest levels of transient growth and are short-lived. The Orr mechanism is key to the amplification of energy for 2D perturbations. In this work, we discuss 2D non-modal perturbations of three-layer viscosity stratified flows with the mean shear rates of the outer layers being equal. Strikingly, a novel regenerative Orr mechanism is found that allows for significant amount of energy amplification despite the 2D nature of the perturbations. Moreover, these perturbations survive for considerably long times. The perturbation structure shows symmetry about the middle layer and evolves such that the Orr mechanism can repeatedly occur in a regenerative manner resulting in the perturbation energy evolving in a markedly non-monotonic fashion. When these same perturbations are introduced in a uniform plane shear flow, the corresponding non-modal transient amplifications are shown to be much smaller.

Subcritical transitional flow in two-dimensional plane Poiseuille flow

Recently, subcritical transition to turbulence in the quasi-two-dimensional (quasi-2-D) shear flow with strong linear friction (Camobreco et al., J. Fluid Mech., vol. 963, 2023, R2) has been demonstrated by the 2-D mechanism at $Re = 71\,211$ , and the nonlinear Tollmien–Schlichting (TS) waves related to the edge state were approached independently of initial optimal disturbances. For 2-D plane Poiseuille flow, transition to the fully developed turbulence requires that the Reynolds number is several times larger than the critical Reynolds number $Re_c$ (Markeviciute & Kerswell, J. Fluid Mech., vol. 917, 2021, A57). In this paper, we observed the subcritical transitional flow in 2-D plane Poiseuille flow driven by the nonlinear TS waves by both linear and nonlinear optimal disturbances ( $Re < Re_c$ ) with different quantitative edge states. The nonlinear optimal disturbances could trigger the sustained subcritical transitional flow for $Re \geqslant 2400$ . The initial energy for nonlinear optimal disturbance is more efficient than the linear optimal disturbance in reaching the subcritical transitional flow for $2400 \leqslant Re \leqslant 5000$ . Moreover, the initial energy of linear optimal disturbance is larger than the energy of its edge state. The nonlinear TS waves along the edge state are formed by the nonlinear optimal disturbances to trigger transitional flow, which agrees well with the main conclusions of Camobreco et al. (J. Fluid Mech., vol. 963, 2023, R2), while the required $Re$ of 2-D plane Poiseuille flow is much smaller.

Investigation into the Computational Analysis of High–Speed Microjet Hydrogen–Air Diffusion Flames

High-speed microjet hydrogen–air diffusion flames are investigated computationally. The focus is on the prediction of the so-called bottleneck phenomenon. The latter has been previously observed as a specific feature of the present flame class and has not yet been investigated computationally. In the configuration under consideration, the nozzle diameter is 0.5 mm and six cases with mean nozzle injection velocities (U) between 306 m/s and 561 m/s are considered. The flow in the nozzle lance is analyzed separately to obtain detailed inlet boundary conditions for the flame calculations. It is confirmed by calculation that the phenomenon is mainly determined by the transition to turbulence in the initial parts of the free jet. The transitional turbulence proves to be the biggest challenge in predicting this class of flames, as the generally available turbulence and turbulent combustion models reach the limits of their validity in transitional flows. In a Reynolds-Averaged Numerical Simulation framework, the Shear Stress Transport model is found to perform better than alternative two-equation models and is used as the turbulence model. By neglecting the interactions between the turbulence and chemistry (no-model approach), it is possible to predict the morphology of the bottleneck flame and its dependence on U qualitatively. However, the position of the bottleneck is overpredicted for U < 561 m/s. The experimental flames in the considered U range are all attached to the nozzle. This is also predicted by the no-model approach. The Eddy Dissipation Concept (EDC) used as the turbulence combustion model predicts, however, lifted flames (with increasing lift-off height as U decreases). With the EDC, no bottleneck morphology is observed for U = 561 m/s. For lower U, the EDC results for the bottleneck position are generally closer to the measurements. It is demonstrated that accuracy in predicting the bottleneck position can be improved by ad hoc modifications of the turbulent viscosity.

Measurement of blood-brain barrier water exchange rate using diffusion-prepared and multi-echo arterial spin labelling: Comparison of quantitative values and age dependence.

Water exchange rate (Kw) across the blood-brain barrier (BBB) is an important physiological parameter that may provide new insight into ageing and neurodegenerative disease. Recently, two non-invasive arterial spin labelling (ASL) MRI methods have been developed to measure Kw, but results from the different methods have not been directly compared. Furthermore, the association of Kw with age for each method has not been investigated in a single cohort. Thirty participants (70% female, 63.8 ± 10.4years) were scanned at 3T with Diffusion-Prepared ASL (DP-ASL) and Multi-Echo ASL (ME-ASL) using previously implemented acquisition and analysis protocols. Grey matter Kw, cerebral blood flow (CBF) and arterial transit time (ATT) were extracted. CBF values were consistent; approximately 50 ml/min/100 g for both methods, and a strong positive correlation in CBF from both methods across participants (r = 0.82, p < 0.001). ATT was significantly different between methods (on average 147.7ms lower when measured with DP-ASL compared to ME-ASL) but was positively correlated across participants (r = 0.39, p < 0.05). Significantly different Kw values of 106.6±19.7min-1 and 306.8±71.7min-1 were measured using DP-ASL and ME-ASL, respectively, and DP-ASL Kw and ME-ASL Kw were negatively correlated across participants (r = -0.46, p < 0.01). Kw measured using ME-ASL had a significant linear relationship with age (p < 0.05). In conclusion, DP-ASL and ME-ASL provided estimates of Kw with significantly different quantitative values and inconsistent dependence with age. We propose future standardisation of modelling and fitting methods for DP-ASL and ME-ASL, to evaluate the effect on Kw quantification. Also, sensitivity and bias analyses should be performed for both approaches, to assess the effect of varying acquisition and fitting parameters. Lastly, comparison with independent measures of BBB water transport, and with physiological and clinical biomarkers known to be associated with changes in BBB permeability, are essential to validate the ASL methods, and to demonstrate their clinical utility.

Analysis of Paradigms in Organizational Theory and Their Implications on Organizational Communication

This study aims to analyze the paradigm in organizational theory and its implications for organizational communication. Descriptive is the method used in this research. The method used is helpful in describing various organizational theories and their implications for organizational communicatioan. In addition, a qualitative approach is used to assist descriptive methods in describing various theories. The results obtained indicate that different perspectives on the organization affect the role of communication in the organization. Classical flow theory views that communication has a function as a supervisor from management to employees. While the transitional flow, communication within the organization is a communication that involves executives and employees. As well as the critical flow, communication within the organization can not be separated from the culture in the organization.

Perioperative anesthetic management of patients with hypoplastic left heart syndrome undergoing the comprehensive stage II surgery-A review of 148 cases.

Patients with hypoplastic left heart syndrome undergo the comprehensive stage 2 procedure as the second stage in the hybrid approach toward Fontan circulation. The complexity of comprehensive stage 2 procedure is considered a potential limitation, and limited information is available on its anesthetic management. This study aims to address this gap. A single-center retrospective cohort study analyzed 148 HLHS patients who underwent comprehensive stage 2 procedure, divided into Group A (stable condition, n = 116) and Group B (requiring preoperative intravenous inotropic therapy, n = 32). Demographic data, intraoperative hemodynamics, anesthetic management, and postoperative outcomes were collected. Etomidate (40%) was the most common induction agent, followed by esketamine (24%), midazolam (16%), and propofol (13%). Inhaled induction was rarely necessary (2%), occurring only in Group A patients. No statistical differences were found between groups for induction drug choice. Post-cardiopulmonary bypass management included moderate hypoventilation, inhaled nitric oxide (100%), and hemodynamic support with milrinone (97%) and norepinephrine (77%). Group B patients more frequently required additional levosimendan (20%) and epinephrine (18%). Extracorporeal membrane oxygenation was necessary in 8 patients (5%) with no between-group differences. Switching from fentanyl to remifentanil reduced postoperative ventilation time overall. However, Group B experienced significantly longer ventilation (6.3 vs. 3.5 h) and ICU stay (22 vs. 14 days). In-hospital mortality was 5% overall (Group A: 4%, Group B: 9%). Long-term survival analysis revealed a significant advantage for Group A. The use of short-acting opioids and adjusted ventilation modes enables optimal pulmonary blood flow and rapid transition to spontaneous breathing. Differentiated hemodynamic support with milrinone, norepinephrine, supplemented by levosimendan and epinephrine in high-risk patients, can mitigate the effects on the preoperatively volume-loaded right ventricle. However, differences in long-term survival probability were observed between groups. Local ethics committee, Medical Faculty, Justus-Liebig-University-Giessen (Trial Code Number: 216/14).