The aim of the research is to analyze the impact of the Russian-Ukrainian war (political conflict) and global political problems on the socio-economic development of the state. The Russian-Ukrainian war leads to an economic crisis, a drop in incomes and welfare, and an increase in unemployment. In addition, environmental problems caused by war crimes lead to an increase in the number of diseases and slow down socio-economic development. The study was conducted in Ukraine from the start of a full-scale Russian invasion (February 2022) to April 2023. The following scientific approaches were used: political, conflict, and typological. As well as general scientific methods: analysis and synthesis, systematic method, induction and deduction, generalization. The results emphasize that one of the reasons for the Russian-Ukrainian war is the different political and socio-economic interests that lead to the war. This study's findings underscore the global ramifications of a full-scale conflict within Ukraine's borders. Moreover, it highlights the substantial impact of political conflicts and global political challenges as destabilizing factors, casting a detrimental influence on the socio-economic progress of the nation. The scientific novelty of the study consists in a comprehensive and systematic analysis of the impact of the Russian-Ukrainian war on the socio-economic development of Ukraine.