Groundwater is vital to the well-being of over 20 million people in the nearly 2000-mile-long, arid U.S.–Mexico border region, supporting agricultural, industrial, domestic, and environmental needs. However, persistent droughts over the past two decades, coupled with increasing water demand and population growth, have significantly strained water resources, threatening the region’s water security. These challenges highlight the importance of comprehensive transboundary aquifer assessments, such as those conducted through the Transboundary Aquifer Assessment Program (TAAP), a collaborative effort between the U.S. and Mexico to evaluate shared aquifers. The TAAP focuses on four aquifers: the Santa Cruz and the San Pedro in Arizona and Sonora and the Mesilla and the Hueco Bolson in Texas, New Mexico, and Chihuahua. With the need for additional aquifer studies in this arid region, it is important to determine and prioritize which aquifers would benefit most from transboundary assessment. This study aims to prioritize aquifers in the Arizona–Sonora region based on multiple criteria. The results from this study reveal regional disparities in the need for transboundary aquifer studies, with some aquifers highlighted due to their groundwater use for economic activities, while others stand out for their population density and the transboundary nature of the hydrogeologic units. By leveraging publicly available data, this research established a priority ranking for these aquifers to support decision-making processes in identifying and addressing the most critical aquifers for binational assessment, while providing a framework that can be replicated across other shared aquifers between the U.S. and Mexico and elsewhere.
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