Body Resistance Research Articles

Study on the Impact of Tail Wing Profiles on the Resistance Characteristics of Amphibious Vehicles

The resistance performance of amphibious vehicles can be improved by installing underwater tail hydrofoils. The research on the impact of different hydrofoil profiles on the resistance characteristics of amphibious vehicles can provide a reference for the vehicle’s design. For an amphibious vehicle model, five shapes of symmetrical hydrofoils, NACA0012, NACA0015, NACA0016, and asymmetric hydrofoils NACA23012, NACA66-209, were selected as the underwater tail wing of the vehicle body, respectively. Based on the RANS method and overset grid technology, the resistance performance of the vehicle body was numerically calculated, and the resistance variation in the amphibious vehicle equipped with different tail hydrofoils at 0.43 < Fr∇ < 1.3 speed was obtained. The basic shape of amphibious vehicle tail wings can be determined by comparing the effects of symmetrical hydrofoils and asymmetric hydrofoils on body resistance. The results show that the asymmetric hydrofoils have a better resistance reduction effect on amphibious vehicles than the symmetrical ones. Among them, an amphibious vehicle installing the asymmetric hydrofoil NACA66-209 as an underwater tail wing can reduce resistance by 44.3%. Chord length is an important factor affecting the resistance reduction performance of tail wings. When Fr∇ = 1.3, the asymmetric hydrofoil optimized based on chord length has a 21.2% higher resistance reduction effect on amphibious vehicles.

Effect of Crystallinity on the Field Emission Characteristics of Carbon Nanotube Grown on W-Co Bimetallic Catalyst.

Carbon nanotube (CNT) is an excellent field emission material. However, uniformity and stability are the key issues hampering its device application. In this work, a bimetallic W-Co alloy was adopted as the catalyst of CNT in chemical vapor deposition process. The high melting point and stable crystal structure of W-Co helps to increase the grown CNT diameter uniformity and homogeneous crystal structure. High-crystallinity CNTs were grown on the W-Co bimetallic catalyst. Its field emission characteristics demonstrated a low turn-on field, high current density, stable current stability, and uniform emission distribution. The Fowler-Nordheim (FN) and Seppen-Katamuki (SK) analyses revealed that the CNT grown on the W-Co catalyst has a relatively low work function and high field enhancement factor. The high crystallinity and homogeneous crystal structure of CNT also reduce the body resistance and increase the emission current stability and maximum current. The result provides a way to synthesis a high-quality CNT field emitter, which will accelerate the development of cold cathode vacuum electronic device application.

Amrita: The ancient herb with modern healing potential and safety features

Tinospora cordifolia Willd commonly known, as “Amrita” or “Guduchi”, is a large deciduous, extensively spreading climbing shrub with several coiling branches, a dioecious medicinal herb. It is designated as Rasayana in Ayurveda as it enhances general body resistance and promotes longevity, an anti-stress, adaptogen, and a potential plant for providing resistance against infections. The plant is well known as Indian bitter and is generally prescribed for fever, diabetes, dyspepsia, jaundice, urinary problems, skin diseases, gastrointestinal diseases including dyspepsia, flatulence, gastritis, jaundice, chronic diarrhea and dysentery, splenomegaly, and hemorrhoids. The herb has been reported to be significant for the management of cardiovascular diseases (CVDs), and the treatment of leprosy, helminthiasis, and rheumatoid arthritis. Some of the most significant formulations in which Guduchi is prime ingredient are Guduchyadi churn, Guduchi taila, Dashmoolarishtha, Sanjivani vati, Punchnimba churana, Guduchi ghrita, Amritaguggulu, Amritashtaka churna, Kantakari avaleha, Chyavanaprasha, Guduchi sattva, Brihat guduchi taila, Stanyashodhana kashaya churana. The most dominant constituents in guduchi include terpenoids, alkaloids, tannins, cardiac glycosides, flavonoids, saponins, lignans, steroids, C6-C3 derivatives and polysaccharides along with other components. There are no adverse effects of any kind reported so far as prescribed under reasonable dose application. It has promising potential as a tonic in infants and stimulates immunity in children besides facilitating growth. Due to the presence of immense medicinal properties, this plant has been over-exploited by pharmaceutical companies and folk people for traditional remedies. This in turn has led to the acute scarcity of this plant. Therefore, it is of prime importance and urgent need for its conservation.

On the Possibility of Using the Topical form of the Recombinant Interferon alpha-2b Drug in the Prevention of Acute Respiratory Viral Infections in Organized Groups

Relevance. Respiratory infections are an urgent problem for organized groups, including military ones, since the transmission of pathogens by airborne droplets and household contact routes, physical and psychological stress on adaptive mechanisms contribute to the development of the epidemic process. There is no doubt that vaccination makes a significant contribution to the prevention of respiratory infections, but the contingent remains vulnerable to other pathogens against which there are no vaccines. Therefore, the search for new methods of non-specific prevention is necessary in maintaining the health of persons permanently residing in collectives. Aim. Evaluation of the possibility of using the topical form of the recombinant interferon α-2b drug for the prevention of acute respiratory viral infections in organized groups. Materials and methods. The work was carried out according to the methodology of a multicenter (3 Centers) double-blind controlled trial involving 3,235 people aged 18 to 22 years, who were divided into three groups: 1 gy. - received a recombinant interferon α-2b (Grippferon) drug 3 drops in each nasal passage 2 times a day in for two weeks; 2 g. - saline solution intranasally according to the same scheme; 3 g. - the volunteers did not receive anything. The frequency of respiratory infections was studied. Results and discussion. Medical monitoring of the study participants, which was carried out for 2 months, showed that in the groups from the Center 1, the incidence of acute respiratory diseases for 2 months in the main group (gr. 1) was 2.3 times lower than in the control (gr. 2) and the comparison group (gr. 3). In the Center 2 The data corresponded to the dynamics of Center 1: the incidence values were 2.4-2.5 times lower in Group 1. In Center 3, the values were 2.0-2.1, respectively. The epidemic effect of intranasal administration of the topical form of the drug recombinant interferon α-2b is due to its effect on the factors of mucosal immunity, which contributes to non-specific protection and increased body resistance against respiratory infections. Conclusions. The presented advantages of the recombinant interferon α-2b drug make it possible to draw attention to the clinical feasibility of its use for preventive purposes in organized groups, including military ones, from the position of high epidemiological effectiveness, both pre-exposure and post-exposure prevention of acute respiratory viral infections.

Pathogenesis of ferroptosis on chronic kidney disease and traditional Chinese medicine intervention: a review

Chronic kidney disease(CKD) is an insidious disease that has become a significant global public health issue due to its high incidence rate, low awareness, low diagnostic rate, poor prognosis, and high medical costs. Recent studies have shown that CKD development is associated with varying degrees of ferroptosis features. Traditional Chinese medicine(TCM) can regulate iron metabolism, lipid peroxidation, antioxidant systems to inhibit ferroptosis and delay the progression of CKD. Consequently, the intervention mechanism of ferroptosis has become one of the focuses of CKD research. TCM has thousands of years of traditional experience and wisdom. It focuses on the overall regulation of human body functions and can stimulate the body's disease resistance and recovery capabilities, which has certain advantages in treating CKD. However, there is currently a lack of comprehensive articles on the application of TCM in intervening ferroptosis to treat CKD and the pathogenesis of ferroptosis in CKD. Therefore, this article summarizes the latest research progress both domestically and internationally, briefly introduces the main mechanisms of ferroptosis, and systematically reviews the relationship between ferroptosis and CKD. The article integrates TCM theories related to ferroptosis in CKD, including "deficiency" "stasis" "phlegm turbidity" and "toxins" and summarizes the research status of active ingredients and herbal formulas in intervening ferroptosis to treat CKD. By considering ferroptosis from a new perspective, this article aims to provide new targets and directions for the application of TCM in treating CKD.

COMBINED HIGH-INTENSITY INTERVAL TRAINING FOR PEOPLE WITH DISORDERS OF GUT BRAIN INTERACTION: A CASE REPORT

AIMS The efficacy of high intensity exercise for improving symptoms of chronic idiopathic constipation, a highly prevalent disorder of gut brain interaction (DGBI), remains uncertain. The aim of this case report was to investigate the feasibility, safety, and efficacy of 8-weeks of combined high-intensity interval training (C-HIIT) for a person (female, 23 years old) with chronic constipation. METHODS The participant enrolled in the C-HIIT for DGBI controlled trial that aims to recruit 32 participants with DGBI. Following comprehensive assessments of gastrointestinal symptoms, neuromuscular fitness, cardiorespiratory fitness and mental health, the participant completed an 8-week intervention consisting of thrice weekly 26-minute C-HIIT sessions. These consisted of a 3-minute aerobic warm-up (treadmill; 50-60% peak heart rate [HRpeak]) followed by 4-minutes of high-intensity aerobic exercise at ≥85% HRpeak. After 1-minute rest, eight whole body resistance exercises were performed. These involved continuous repetitions with good technique for 1-minute at an ≥8/10 (very hard) rating of perceived exertion; 1-minute rest separated each exercise. Adverse events were recorded throughout the intervention. RESULTS The participant adhered to the intervention, attending 100% of sessions and reaching the prescribed intensity for 100% of aerobic and 80% of resistance exercises. Efficacy of the exercise training was indicated by a reduction in the severity of gastrointestinal symptoms measured via the irritable bowel syndrome-symptom severity scale (from 111 to 100) and the structured assessment of gastroIntestinal symptoms (39 to 12). There were some improvements in neuromuscular fitness (handgrip strength: 27 to 29.5 kg, 30-second sit to stands: 12 to 10 repetitions) and cardiorespiratory fitness (VO2max: 36.7 to 38.2 mL/kg/min). No changes were observed in mental health (Hospital Anxiety and Depression scale), and one non-serious adverse event (nausea post-eating), which was deemed not related to the intervention. CONCLUSION The C-HIIT intervention in a person with DGBI was feasible, efficacious and safe.

Pemanfaatan Teh dan Rempah-rempah Khas Indonesia dalam Pemeliharaan Kesehatan Warga di Sumba Timur Menghadapi Pandemi Covid-19

The coronavirus (SARS-CoV-2) has infected nearly 4 million people worldwide. This virus was first identified in Wuhan, China, in December 2019. Every day positive cases of Covid-19 are increasing in the world. Experts are still trying to find a vaccine to prevent this virus, one of which is by increasing the body's resistance (immunity). The use of family medicinal plants (TOGA) or tea, a drink that we usually drink every day is believed to increase one's body immunity. The content of natural chemicals in tea such as EGCG and curcumin found in the rhizomes have antioxidant activity and is clinically proven to increase a person's immunity.

Sargassum sp. extract improve hematological profile of tilapia fish (Oreochromis niloticus)

Background Strategies to increase body resistance and prevent disease in aquaculture include using vaccines, antibiotics, and probiotics. Today, the use of antibiotics with natural ingredients is becoming a trend. Sargassum sp is a natural ingredient that contains high antioxidants and antibiotics. Methods This research was conducted from March to May 2022 at the Biotechnology Laboratory, Faculty of Fisheries and Marine, Universitas Riau, in two stages: 1) the sensitivity of extracts of Sargassum sp. and 2) the application of Sargassum sp. extract orally in tilapia (O. niloticus). The parameters measured were clear zone, minimum inhibitory concentration, LD50 test of leaf extract of Sargassum sp. in tilapia (O. niloticus), hemoglobin levels, hematocrit, total leukocytes, total erythrocytes, leukocyte differentiation, and survival rate. Data on hematology parameters were tabulated and analyzed using a One-Way ANOVA followed by a Student Newman Keuls (SNK) test when deemed necessary. Results The results showed that the extract of Sargassum sp. inhibited the growth of Aeromonas hydrophila bacteria with a clear zone of 6.5-15.0 mm, which is classified as resistant. At doses of 2000, 2500, and 3000 ppm, it did not cause death in fish for 96 hours (LD50). Hematological parameters can be a sign of the health status of fish. Tilapia given Sargassum sp. in different doses gave an effect between treatments after 30 days of rearing and post-test against A. hydrophila bacteria (p<0.05). The results showed that the hematology of fish fed with Sargassum sp. extract was in the normal or healthy range. Healthy tilapia had erythrocyte counts ranging from 1.34-2.11×106 cells/mm3, hematocrit 26.17-33.19%, hemoglobin 6.26-11.2 g/dL and total leukocytes 1.01-1.50×104 cells/mm3 and total erythrocytes 5.88-9.13×104 cells/ mm3. Conclusions A dose of 3000 ppm provided the highest health improvement against A. hydrophila bacterial infection.

Wave resistance of slender body in unsteady motion under an ice sheet

The paper is devoted to the theoretical study of the rectilinear unsteady movement of a slender body in a liquid near the free surface and an ice sheet. Water is an ideal incompressible liquid, and the motion of the liquid is potential. The ice cover is modeled by a floating viscoelastic plate. The viscoelastic properties of ice are described using the Kelvin–Voigt model. A slender body of a given shape in the liquid flow is modeled by the flow of the source-sink system. Various modes of body movement are considered: acceleration, deceleration, movement at a given speed. The effect of the ice sheet, acceleration and deceleration of the body on its wave resistance is analyzed. It is obtained that unsteady modes of motion (acceleration and deceleration) significantly affect the wave resistance of a slender body. Motion with low initial acceleration makes it possible to reduce amplitude of the first-time hump of wave resistance. During body deceleration to a full stop, the curve of wave resistance has an oscillations. Reduction of deceleration coefficient results in decrease of oscillation amplitude of wave resistance curve. The presence of the ice cover smoothes the hump of wave resistance during acceleration and reduces the number of oscillations and their amplitude during deceleration.

Antioxidant and anti-aging activities of Longan crude and purified polysaccharide (LP-A) in nematode Caenorhabditis elegans

Oxidative damage is an important cause of aging. The antioxidant and anti-aging activities of Longan polysaccharides, especially purified Longan polysaccharides, have not been thoroughly investigated. Therefore, this study aimed to investigate the antioxidant and anti-aging activities and mechanisms of crude polysaccharides and purified polysaccharides from Longan. A purified acidic Longan polysaccharide LP-A was separated from Longan crude polysaccharide LP. Subsequently, its structural characterization, anti-aging activity and mechanism were studied. The results showed that LP-A was an acidic heteropolysaccharide with an average molecular weight (Mw) of 4.606 × 104 Da which was composed of nine monosaccharides. The scavenging rate of ABTS free radical in vitro reached 99 %. In the nematode life experiment, 0.3 mg/mL LP group and LP-A group could prolong the average lifespan of nematodes by 9.31 % and 25.80 %, respectively. Under oxidative stress stimulation, LP-A group could prolong the survival time of nematodes by 69.57 %. In terms of mechanism, Longan polysaccharide can regulate insulin / insulin-like growth factor (IIS) signaling pathway, increase the activity of antioxidant enzymes, reduce lipid peroxidation, enhance the body's resistance to stress damage, and effectively prolong the lifespan of nematodes. In conclusion, LP-A has better anti-aging activity than crude polysaccharide LP, which has great potential for developing as an anti-aging drug.

Experience of using immunomodulatory therapy in the complex treatment of mild community-acquired pneumonia and its long-term results

A decrease of nonspecific body resistance, an imbalance of local and systemic immunity and a free-radical oxidation abnormality substantially contribute to the pathogenesis of community-acquired pneumonia (CAP).Purpose: To study the efficiency of including immunomodulators into the comprehensive treatment of nonsevere community-acquired pneumonia and assess the long-term effects of the treatment conducted.Patients (n = 55) with non-severe CAP (41 (31-48) years old, with CRB-65 score of 0.15 (0-1)) are included in the study. Group 1 (control) received only standard CAP therapy; the other two groups received immunomodulators concurrently with the standard therapy: bacterial lysate (BL) for group 2 and azoximer bromide (AzB) for group 3. TNFα and IL-6 concentration was determined on the day of visit, on day 13 and day 60 of follow-up. During 2 years, the incidence of low respiratory tract infections (LRTI) was studied in the same patients with CAP in past (n = 55). All patients (n = 55) had clinical signs of non-severe community-acquired pneumonia. The overall duration of all symptoms was lower in immunomodulators groups as compared to the control group: 12 (11-13) days in BL group (p < 0.001) and 12 (11-12) days in AzB group (p < 0.001) with no statistically significant difference between intervention groups (p = 0.36). During treatment, TNFα and IL-6 concentration decreased on day 13 and day 60 in all patients; in patients who received immunomodulators, TNFα and IL-6 were reliably lower as compared to the control. Changes of TNFα and IL-6 concentration in the groups on day 60 of the study as compared to the baseline showed a decrease in BL group by 85 (-89 – -82) % and 86 (-90 – -85) % (p < 0.001; p = 0.001 and control); in AzB group by 82 (-86 – -80) % and 86 (-88 – -84) % (p = 0.002; p = 0.007 and control). Intensity of IL-6 concentration decrease on day 60 in BL and AzB groups did not differ (p = 0.72). Gender- and age-adjusted odds ratio for the development of low respiratory tract diseases (during 2 years after CAP) in AzB group was 0.15 (0.02-0.93) (p = 0.04) suggesting its protective effect. Inclusion of immunomodulators in basic treatment of non-severe community-acquired pneumonia reduces duration of symptoms and is associated with improvement of the proinflammatory cytokine profile. In 2 years of follow-up, long-term effects of the immunomodulatory therapy showed statistically significant lower incidence of low respiratory tract infections in AzB group only.

MORPHOLOGICAL CHANGES IN THE HIPPOCAMPUS OF THE RAT BRAIN IN ISCHEMIA AND IN CONDITIONS OF COMBINED PRECONDITIONING

BACKGROUND: Preconditioning is an effective method of increasing the body's resistance to hypoxia/ischemia.
 AIM: The aim is to evaluate morphological changes in the most hypoxia-sensitive fields of the hippocampus CA1 and CA3 in cerebral ischemia in rats and under conditions of combined preconditioning.
 MATERIALS AND METHODS. Cerebral ischemia was simulated in rats under anesthesia (8% chloral hydrate solution 400 mg/kg) by bilateral ligation of the common carotid arteries. The combined preconditioning method (CPreC) included the alternate use of two preconditional factors – pharmacological (amtisol at a dose of 25 mg /kg) and hypoxic (hypobaric hypoxia, 410 mmHg, exposure time 60 min). Morphometric assessment of brain damage was performed a day after modeling ischemia in the CA1 and CA3 fields of the hippocampus.
 RESULTS. KPreK has a positive effect on the morphometric parameters of the brain during its ischemia, increasing the survival of neurons in the early and late periods of ischemia modeling, preventing the formation of necrotically and apoptotically altered neurons, hyperactivation of microglial cells and contributing to the preservation of endotheliocytes. 
 CONCLUSION. KPreK (amtisol + hypobaric hypoxia) has a neuroprotective effect in cerebral ischemia.

The feasibility of using soybean raw materials

The most important determinant of public health is a balanced, nutritious diet that ensures normal human growth and development, life expectancy, increases the body's resistance to adverse environmental conditions, and leads to progress and improvement of the quality of life. The article presents the reasonable reasons for the expediency of using soybean raw materials, which led to the emergence of mass consumption products available to all groups of the population, which can be used regularly in everyday, dietary, therapeutic or preventive nutrition with a high degree of digestibility and assimilation of food, in accordance with the recommendations, while maintaining an adequate level of energy intake per day. Given the difficulties our country is experiencing due to martial law, there is a problem of expanding and, in some regions, providing a sufficient range of domestic food products that include energy components: proteins, fats and carbohydrates. There is a decrease in the production of domestic meat raw materials due to the problems faced by farms in today's difficult conditions. The article investigates the chemical composition and energy value of soybeans and soy products. The comparative characterization of soybeans and soybean products is also carried out. The proposal to enrich the range of food products with soybean processing products is also substantiated. With the further prospect of developing technologies for adding and enriching soybean processing products to raw materials of animal origin. The feasibility of these technologies is based on the chemical composition of soybeans. After all, soybeans and soy products are protein components, the value of which is primarily represented by polyunsaturated fatty acids, isoflavonoids, phospholipids, enzymes, carbohydrates, dietary fiber, minerals, as well as vitamins E, B, PP and other physiologically valuable nutrients. It is clear that in order to maximize the extraction of native nutrients, it is important to use special methods and economical modes of technological processing of raw materials. The article also describes the main types of soybean seed processing products with high nutritional and biological value available on the Ukrainian market.

Comparative analysis of the effectiveness of probiotic enterococcus strains in gastroenteritis in piglets

According to a number of authors, a sharp change in the type of feeding and the effects of stress factors in piglets after weaning lead to disorders not only of metabolism, but also of membrane digestion, which further contributes to a decrease in body resistance and the occurrence of various diseases of the digestive organs.In the course of our study, it was found that the use of probiotic strains Enterococcus faecium L-3 and Enterococcus faecium 1-35 for the treatment of gastroenteritis in piglets during weaning had a similar effect on restoring intestinal enzymatic activity. In piglets that were not treated with probiotics (control 1), enzymatic activity in the digestive tract was only partially normalized during the study. We also evaluated some parameters of the ongoing metabolic processes in the body of weaning piglets by studying the biochemical blood parameters of the experimental groups after prescribing the probiotic strain Enterococcus faecium L-3 (experiment 1) and Enterococcus faecium 1-35 (experiment 2) comparing them with those of the control group of animals.

PENYULUHAN PERAN ASI EKSKLUSIF TERHADAP TUMBUH KEMBANG ANAK DITENGAH WANITA PEKERJA PEDAGANG PASAR TRADISIONAL

Exclusive breastfeeding is giving breast milk to babies from 0-6 months of age exclusively without additional food or drink. Exclusive breastfeeding provides many benefits for both baby and mother. Some of the benefits of exclusive breastfeeding for babies are increasing the baby's body resistance or antibodies against disease attacks and helping the baby's brain and physical development. For the Deli Serdang Regency area, the percentage of babies who receive exclusive breast milk is only 47.26%. From these data it can be seen that there is still a lack of exclusive breastfeeding for babies. The low level of exclusive breastfeeding will have an impact on the quality and vitality of the next generation. One of the factors that hinders exclusive breastfeeding is working mothers, especially in the informal sector such as traditional market traders. This PKM activity using the counseling method aims to provide information to breastfeeding mothers about the role of exclusive breastfeeding in the growth and development of babies among women who work as traders at the Deli Tua traditional market. The process of implementing this community service activity is carried out by providing information and education to respondents regarding the role of exclusive breastfeeding in the growth and development of babies and tips on how to meet the needs of exclusive breastfeeding for children among women who work as traditional market traders. Then the respondents distributed pre-test and post-test questionnaires to the participants and the results obtained were 76.9% of the 13 respondents had increased knowledge regarding the role of exclusive breastfeeding in the growth and development of babies and tips on how to meet the needs of exclusive breastfeeding for children among working women. as a traditional market trader.

Indicators of the general resistance of breeding bulls depending on age, origin and breed

Humoral factors such as bactericidal and lysozyme activity are the most significant for the body's resistance. The purpose of the research was to study the nonspecific resistance of sires depending on age, place of adaptation before entering the Russian Federation, origin and breed. The work was carried out at JSC “Head Reproduction Center” (JSC “GCV”) on animals aged from 2 to 9 years in the amount of 34 heads. Such indicators as the percentage of lysis, the amount of lysozyme (mcg) in 1 ml of blood serum, specific units of activity (u.a.) calculated per 1 mg of protein and the bactericidal activity of blood serum as a percentage were studied. Lysozyme (LASK) and bactericidal activity (BASK) were studied using a Multiskan FC microbiological analyzer (Finland). Thus, it has been established that the general resistance of sires depends on age and has significant differences between animals of different age groups. At the age of 2-3 years there is no reliability. Significant differences between bulls according to the parameters we studied begin from 5 years of age at P <0.05 in the concentration of total protein and lysozyme and specific units. A. squirrel. Age range had no effect on BAS. More noticeable significant differences were recorded in animals (of contrasting age periods) in terms of general resistance and had significant differences at the level of P≤0.01 in the percentage of lysis, in the amount of lysozyme in the blood serum (P≤0.001), and specific units of activity (P≤0.001). It was found that sires coming from different regions of Europe (the Netherlands and Germany + Luxembourg) in the same age range do not have significant differences among themselves in the overall resistance of the parameters we studied (BASK and LASK) under the conditions of their operation in the Moscow region RF.

THE EFFECT OF LOCAL ANESTHESIA ON HEALING TIME PERINEUM WOUNDS ON NIFAS' MOTHER AT PMB NUNUNG TANGERANG

Background: WHO in 2020, stated that maternal deaths during pregnancy, childbirth and postpartum were 295,000 worldwide. Africa, Sub-Saharan and South Asia account for about 86%. Meanwhile, the maternal mortality rate in Indonesia in 2020 is 230 per 100,000 live births. One of the causes of maternal death is bleeding and infection. Suturing perineal tears with anesthesia is one of the maternal care programs, which aims to reduce the pain experienced by mothers during the suturing process of birth canal wounds. Giving anesthesia can also cause damage to the immune system which results in a decrease in body resistance so that there will be a lengthening of wound healing 2-3 days than without anesthesia. Research Objective: Knowing the administration of local anesthesia on the healing duration of perineal wounds in puerperal mothers. Research Method: Quasi-experiment with post-test group design. The samples in this study were all postpartum mothers who experienced perineal injuries at PMB Nunung in November-December 2023 as many as 40 people. The sampling technique uses the total sampling technique. Results of the study: The frequency distribution of long healing of perineal wounds in the majority intervention group was slow and in the majority control group was fast. The effect of local anesthesia on the healing time of perineal wounds in puerperal mothers (p. value 0.000). Conclusion and Suggestion: The effect of local anesthesia on the healing time of perineal wounds in puerperal mothers. It is expected that midwives provide counseling to postpartum mothers to properly care for perineal wounds and eat nutritious foods to accelerate the healing of perineal wounds.

Association between healthy lifestyles and post-COVID-19 syndrome among college students.

Post-COVID-19 syndrome still occurs in some populations. A healthy lifestyle is widely recognized as a first-line treatment to increase the body's antiviral resistance and tissue repair, but it is unclear whether a healthy lifestyle can promote or alleviate the symptoms of post-COVID-19 syndrome. A stratified random sampling method was used to select 498 participants from three universities in Fujian as the target of the questionnaire survey. The survey focused on students' healthy lifestyles and the symptoms of fatigue, anxiety, dyspnea, and depression that are common in post-COVID-19 syndrome. Two months after developing COVID-19, some students continued to experience fatigue, anxiety, dyspnea, and depression, with fatigue being the most prominent symptom. The results of the study showed that there was a significant negative correlation (P < 0.01) between a healthy lifestyle and fatigue, anxiety, dyspnea, and depression among university students. Furthermore, when analyzing the different subdimensions of healthy lifestyles among university students, it was found that all dimensions showed varying degrees of negative correlation with fatigue, anxiety, dyspnea, and depression, except for health-related behaviors and interpersonal behaviors, which showed no relationship with fatigue (P < 0.01). By improving healthy lifestyles, long-term COVID-19 symptoms can be reduced and improved and contribute positively to patient recovery, providing a viable rehabilitation option for long-term COVID-19 patients.

Gambaran Faktor-Faktor Pemberian Vitamin A Pada Balita Di Puskesmas Kecamatan Muara Satu Kota Lhokseumawe Tahun 2020

Vitamin A has biological activity as retinol that can increase the body's resistance to infectious diseases so that it can reduce morbidity and mortality due to vitamin A deficiency, and has an important role for eye health. Vitamin A deficiency (VAD) is the main cause of blindness in children, Aceh Province ranks the fourth lowest in giving vitamin A, it is estimated 30 million toddlers in Indonesia aged 12-59 months, half of whom suffer from VAD. The role of mothers in giving vitamin A is very important, several factors influence the giving of vitamin A to children, that is the level of mother's education, mother's knowledge, mother's visit to Posyandu, mother's job, and the distance from the mother's house to the Posyandu. The purposes of this research are to know the description of mother's education level, mother's knowledge, mother's visit to Posyandu, mother's job, and distance from mother's house to Posyandu in Muara Satu Subdistrict Health Center, Lhokseumawe City. This research method uses a descriptive approach with cross sectional design and sampling using consecutive sampling technique, for data collection is using primary and secondary data. The results of the research on the description of the factors of giving vitamin A at the Muara Satu Subdistrict Health Center, Lhokseumawe City, find that the mother's education level is low 78.1%, mother's knowledge is less 66.8%, mother's visit to Posyandu is high 53.1%, mother does not have a job 88.4%, and the distance from the mother's house to the Posyandu is near 65.6%. The conclusions of this study are the level of mother's education is low, the mother's knowledge is less, the mother's visit to Posyandu is high, the mother's does not have a job, and the distance between the mother's house to Posyandu is near, these variables are a description of the factors of giving vitamin A at Muara Satu Subdistrict Health Center, Lhokseumawe City.

Specialized product for sports nutrition

The article sets out data on the development of a specialized product for sports nutrition “Fruit-milk bar” with directed preventive properties. A scientific justification of the choice of raw materials with an increased content of the full-fledged protein of animal and plant origin, polyunsaturated fatty acids, easily digestible carbohydrates, organic acids, water-and-fat vitamins, macro-and microelements, bioflavonoids, collagen. The purpose of this study was the scientific substantiation and development of a new specialized product for sports nutrition based on local raw materials with increased food and biological value. The work used generally accepted analytical, physicochemical and technological research methods. The choice of raw materials and the composition of the product aimed at resolving issues to increase the body's resistance to increased physical and neuro-emotional stresses are justified. The recipe is given the product preparation technology, data on the physicochemical and organoleptic indicators of the product, as well as safety indicators, are given.