Body Distortion Research Articles

Efficacy and Ultrastructural Impact of Metarhizium anisopliae and Metarhizium robertsii on Myllocerus subfasciatus.

The ash weevil, Myllocerus subfasciatus, is a significant insect pest that infests brinjal. Both the adults and grubs feed on the leaves and roots, respectively, leading to considerable yield loss. The subterranean habits of the larvae limit the effectiveness of insecticide applications, necessitating the implementation of integrated pest management programs that utilize entomopathogenic fungi. This investigation aimed to identify potential Metarhizium species against ash weevil larvae through scanning electron microscopy (SEM) and histopathology. The ash weevils were mass-cultured on brinjal plants under insect-proof conditions. Eleven Metarhizium sourced from the departmental repository were subjected to pathogenicity tests on second-instar ash weevil larvae, revealing that a concentration of 1 × 106 conidia/mL was optimal for SEM and histological studies. Among the 11 Metarhizium strains examined, the TNAU ENTMA TDM 8 strain produced spores measuring 5.8 µm in length and 2.4 µm in width in both potato dextrose agar (PDA) medium and larvae. SEM analysis indicated that the mycelial adherence and penetration of Metarhizium were most pronounced in the larvae 5 days post inoculation (DPI). Histopathological investigations demonstrated that the TNAU ENTMA TDM 8 strain caused degradation of fat bodies and hemocytes at 3 DPI, and complete body distortion at 7 DPI, while the untreated control exhibited no such effects. The M. robertsii strain TNAU ENTMR GYU 1 displayed slower infectivity compared to the M. anisopliae strains. The TNAU ENTMA TDM 8 strain was determined to be the most effective against M. subfasciatus larvae and can be utilized for managing ash weevil populations.

The Neural Correlates of Body Image Processing in Anorexia Nervosa and Bulimia Nervosa: An Activation Likelihood Estimation Meta-Analysis of fMRI Studies.

Body image concerns are key prognostic and pathogenic factors of anorexia nervosa (AN) and bulimia nervosa (BN). This study aimed to investigate the neural mechanisms underlying body image perception across its two domains of estimation and satisfaction in anorexia and bulimia patients and healthy controls (HC). Systematic searches were conducted across eight databases, including PubMed; Cochrane Library; Ovid; Google Scholar; Sage Journals; Scopus; PsycInfo; and ScienceDirect, from database inception until the 23rd of April 2023. The sample pertained to 14 functional magnetic resonance imaging (fMRI) studies and 556 participants, with tasks primarily including image and silhouette-based body estimation and satisfaction paradigms. ALE meta-analysis was conducted to investigate significant clusters of activation foci across the different studies. Shared activations were observed between HC, AN, and BN patients in cortical regions related to object manipulation and recognition, visuospatial awareness, and memory and negative affect regulation. Differential activation in interoceptive and higher-order cognitive or affective control regions likely hold the key to pathological body distortion. This study outlined commonalities and differences in the correlates driving healthy body mapping and eating disorder pathology. Our findings provide pertinent implications for future research, current clinical interventions, and therapeutic outcomes.

Cotard’s: a controlled single case study of putative perceptual, cognitive and psychological risk factors

ABSTRACT This case study explores the psychological and neuropsychological traits of a 55-year-old woman, D.R., who has Cotard’s, believing her torso has dissolved and food bypasses her legs. Her delusion emerged amid major depressive disorder with psychotic features, following prodromal symptoms like body distortion and somatosensory abnormalities. A neuropsychological assessment during remission revealed low-level visual perceptual deficits in an otherwise intact cognitive profile. Subtle distortions in bodily signals and specific attribution styles were identified as vulnerability factors, suggesting that the delusion may emerge when already strained information processing systems are further challenged. This relates to models of delusion formation.

Negative Body Image and Limited Nutrition Knowledge among Collegiate Dancers Signals Need for Screening and Support.

Introduction: The collegiate environment may exacerbate body image issues and eating disorders (EDs) among dancers. This study seeks to evaluate the complex relationships between body image perceptions, risk of EDs, and nutrition knowledge among collegiate dancers. Methods: A convenience sample of collegiate dancers was recruited via announcements, flyers, and email to complete the Body Image Assessment Scale-Body Dimensions (BIAS-BD), anthropometrics, and an electronic survey evaluating ED risk (Eating Attitudes Test; EAT-26), nutrition knowledge, and dietary habits. Body distortion (perceived vs actual size) and dissatisfaction (perceived vs ideal size) were measured. Data analysis included descriptive statistics and t-tests for group and gender-specific data. Results: Thirty-eight collegiate dancers (82% female, 79% with a healthy BMI) participated in the body image assessment. Females (n = 31) exhibited body distortion (P = .006) with a mean BMI = 22.05, mean perceived BMI = 23.27, and a mean ideal BMI = 21.78. Body dissatisfaction was identified but not statistically significant. Males' perceptions of females' ideal BMI = 25.16 were significantly higher than the females' own perceptions (BMI = 21.78, P = .033). No significant body distortion or dissatisfaction was observed among males (n = 7). Female perceptions of the ideal male BMI = 23.96 aligned closely with males' self-views. On the EAT-26, females (n = 28) average score was 11.82, indicating higher risk than males (n = 4), whose average score was 7.75. High ED risk was identified in 18.75% of participants (EAT-26 scores ≥ 20). Nutrition knowledge was limited, with <50% correct responses. The majority sought dietary advice from peers (65.7%) or friends (57.1%), with 37.1% following restrictive diets (eg, vegan, pescatarian, lactose-free). Conclusion: Collegiate female dancers demonstrated body distortion and ED risk despite maintaining a healthy BMI. The limited nutrition knowledge, reliance on non-expert nutrition advice, and tendency towards restrictive eating patterns observed with increased ED risk is worrisome. Thereby necessitating educational interventions focused on nutrition and body image to maintain the dancers' health.

ENGLISH

Introduction and objectives: Eating disorders are a growing problem in our society, especially among young people. The aim of this study is to know which are the individual and social factors that support and perpetuate the danger of suffering from eating disorders, and their possible consequences on the sports and academic performance of individuals. Material and method: The sample consisted of 395 athletes between 12 and 16 years of age (M = 14.07; SD = 1.35), of whom 142 (35.9%) were female and 253 (64.1%) male. A questionnaire was administered to collect information on sociodemographic data, body image, use of social networks, social relationships, sports practice, risk of eating disorders, and academic and sports performance. In the analysis, firstly, cross-tabulations were carried out to observe the body distortion of the respondents according to body mass index; secondly, a linear regression was performed to analyze the factors influencing the risk of eating disorders. In addition, correlations were performed to find out the relationship between risk of manifesting eating disorders and academic and sports performance. Results: The main result shows that there is a high risk of eating disorders among young athletes, due to a high distortion of body image, which becomes the main determinant factor. In addition, relationships with family and friends have a significant influence on this danger. On the other hand, behaviors related to eating disorders cause academic and sports performance to decrease. Conclusión: Due to these data, it is necessary to generate and promote prevention and early detection guidelines during adolescence.

To Explore the Relationship Between Childhood Trauma and Body Dysmorphic Symptoms in Young Adulthood

Abstract: This study is intended to investigate the connection between the child trauma and body dysmorphic disorders as experienced by the youth in 18-25-year-old age-group. Although the research yielded r=0.271 pval &lt; 0.001 for the relationship between childhood trauma and body distortion symptoms, the findings also indicate a non-significant p value of 0.551 which shows the two variables do not have a causal link among this sample. It appears that the cildhood trauma does not have a direct effect on the geness of body dysmorphic symptoms among teenagers. Research into the complex interaction between the developmental period of childhood and the emergence of body dysmorphic symptoms is still necessary, and additionally, one should consider the factors that could affect this engagement positively. Moreover, the range of interventions that addresses body dysmorphic symptoms should move beyond the usual settings to get at the core of the real factors to successfully help the affected individuals.

Proposal for a Cognitive Reconstruction Program for Female College Students Experiencing Body Dissatisfaction

The aim of this study was to develop and implement a program based on Cognitive Behavior Therapy (CBT) for female college students experiencing body dissatisfaction. To systematize the program development process, we adopted the service design method. First, we conducted In-Depth Interviews (IDIs) to identify the difficulties faced by six female college students who experience body dissatisfaction, and to determine what kind of help they needed. Second, content analysis of the findings revealed that female college students were experiencing emotional-behavior problems which derived from the discrepancy between their ideal body image and the reality. Third, a prototype of a cognitive reconstruction program was developed to help transform their perceived ‘body distortion’ to a rational cognitive concept and thus reduce maladaptive consequences of ‘body dissatisfaction’. The overall program consisted of three therapeutic components and seven steps. Fourth, to assess the effectiveness of the program, survey and IDIs were conducted. The results revealed that it is appropriate to use a cognitive model to solve problems caused by body dissatisfaction, and that understanding and reconstructing one's own cognitive processes can be effective in reducing body dissatisfaction. However, based on feedback from participants, a number of revisions were proposed, such as including sufficient induction regarding the behavioral change.

Benzoate Derivatives Toxicity to Musca domestica Results in Severe Muscle Relaxation and Body Distortion.

The house fly, Musca domestica (Linnaeus) (Diptera: Muscidae), is a significant threat to human and animal health and is also resistant to a variety of insecticides. Plant-derived benzoates are known to have insecticidal activities against various insects. In this study, the larvicidal, pupicidal, and adulticidal activities of benzoate derivatives (benzyl alcohol BA, benzyl benzoate BB, and methyl benzoate MB) were assessed and investigated for their effects on larval structure and acetylcholinesterase activity. Six concentrations (2.5 to 100mg/mL) of benzoate derivatives were applied to larvae and pupae through the residual film method and topical application, respectively. Meanwhile, concentrations from 0.625 to 50mg/L air were applied to adult flies through a fumigation assay. BA and MB achieved promising results against larvae with LC50 values of 10.90 and 11.53mg/mL, respectively. Moreover, BA killed 100% of the larvae at a concentration of 25mg/mL, and MB achieved the same effect at a concentration of 50mg/mL. Regarding the pupicidal activity, MB showed a percentage inhibition rate (PIR) of 100% at a concentration of 100mg/mL, while the same effect was achieved by BA at a concentration of 50mg/mL. Meanwhile, BB did not show any effect on the larvae or pupae at any of the tested concentrations. Moreover, the scanning microscopy observations on the treated larvae by BA and MB estimated flaccid and deformity in the larva body with a shrunken cuticle. Additionally, both BA and MB suppress nerve signal transmission by inhibiting acetylcholinesterase. In conclusion, the results of this study indicate that BA and MB may be useful in control housefly populations. These substances cause severe muscular relaxation and deformities in insects.

Síndrome de Alicia en el País de las Maravillas secundario a infección por SARS-CoV-2

The Alice in Wonderland syndrome is defined by the presence of visual perception disorders with several etiologies, being the most frequent the infections in pediatrics. It is a rare clinical condition, but it is important to recognize it because of the generally self-limited nature. We present a 11 years old child who presented visual body distortions, micropsia and macropsia 48 after SARS-CoV-2 infection. Other organic causes were discarded, maintaining an expectant treatment because of its benign evolution. To point this syndrome associated with SARS-CoV-2 infection, has not yet published right now.

Non-back-drivable clutch based self-locking mechanism of prosthetic joint to improve manipulation stability.

During activities of daily living (ADLs), the wrist is mainly engaged in positioning and directing the hand. Researches have demonstrated that restoring wrist mobility can significantly enhance the manipulation ability, reduce body distortion caused by motion compensation, and improve the quality of life for amputees. However, most daily activities, particularly the delicate ones, place high demands on the ability of wrist to maintain a certain rotation angle, also known as non-back-drivable ability, which poses a challenge to the design of prosthetic wrists. To address this issue, various solutions have been proposed, including motor holding brakes, high reduction ratio reducers, and worm gears. However, the motor holding brake only functions after a power outage and cannot continuously prevent torque from the load end. The latter two solutions may alter the transmission ratio, resulting in reduced movement speed and transmission efficiency. Therefore, how to design a miniaturized non-back-drivable mechanism without changing the transmission ratio so that the forearm rotational freedom can be locked at any position for any duration is a problem to be solved in the research of prosthetic wrist designs. This paper presents a line-contact based non-back-drivable clutch (NBDC) that does not cause changes in the transmission ratio, ensuring the motion performance of the prosthetic limb. At the same time, it does not introduce additional friction in the forward transmission process, guaranteeing the overall efficiency. Most importantly, it only allows the torque transmitting from the motor to the load, prevents the load reversely from driving back even in a power failure condition, significantly improving the stability, safety, and comfort. Detailed kinematic and static analyses of the working process has been conducted, and transient dynamics simulation has been performed to verify its effectiveness. Through experiments, it is demonstrated that the self-locking torque of the output end could reach approximately 600Nmm, and the unlocking torque of the input end is about 80Nmm, which can be effectively integrated in prosthetic wrist rotation joints, contributing to the performance, safety and energy saving of prosthetic joint systems.

Bailando++: 3D Dance GPT With Choreographic Memory.

Our proposed music-to-dance framework, Bailando++, addresses the challenges of driving 3D characters to dance in a way that follows the constraints of choreography norms and maintains temporal coherency with different music genres. Bailando++ consists of two components: a choreographic memory that learns to summarize meaningful dancing units from 3D pose sequences, and an actor-critic Generative Pre-trained Transformer (GPT) that composes these units into a fluent dance coherent to the music. In particular, to synchronize the diverse motion tempos and music beats, we introduce an actor-critic-based reinforcement learning scheme to the GPT with a novel beat-align reward function. Additionally, we consider learning human dance poses in the rotation domain to avoid body distortions incompatible with human morphology, and introduce a musical contextual encoding to allow the motion GPT to grasp longer-term patterns of music. Our experiments on the standard benchmark show that Bailando++ achieves state-of-the-art performance both qualitatively and quantitatively, with the added benefit of the unsupervised discovery of human-interpretable dancing-style poses in the choreographic memory. Code and video demo are available at https://github.com/lisiyao21/Bailando/.

Virtual embodiment in fibromyalgia

Chronic pain alters the experience of owning a body and leads to disturbances in bodily perception. We tested whether women with fibromyalgia (FM) are receptive to bodily illusions of owning a visible and progressively invisible body in immersive virtual reality (VR), and what modulates this experience. Twenty patients participated in two experimental sessions; each session included two conditions in a counterbalanced order. We found that patients with FM could indeed experience virtual embodiment. Sentiment analysis revealed significantly more positive reactions to the progressively invisible body, yet twice as many patients declared they preferred the illusion of a visible virtual body. A linear mixed model revealed that the strength of embodiment was positively associated with body perception disturbances and negatively associated with FM symptoms intensity. No effect of pain during the VR experience nor interoception awareness on embodiment was found. The results indicated that patients with FM are receptive to virtual bodily illusions and that the impact of the embodiment depends on affective reactions, the level of cognitive body distortions, and the intensity of symptoms. Importantly, there is a large variation among patients which should be considered in future VR-based interventions.

Social and Individual Factors Associated with Eating Disorders in Young Athletes: Effects on Concentration and Fatigue.

Eating disorders are a growing societal problem, especially among young people. This study aims to determine the individual and social factors that support and perpetuate the risk of eating disorders (ED) and their possible consequences on an individual's athletic and academic performances. The sample consisted of 395 athletes between 12 and 16 years of age (M = 14.07; SD = 1.35), of whom 142 (35.9%) were female, and 253 (64.1%) were male. A questionnaire was administered to collect information on sociodemographic data, body image, use of social networks, social relationships, sports practice, risk of developing ED, and academic and sports performance. In the resulting analysis, an initial cross-tabulation was carried out to observe the body distortion of the respondents as a function of BMI, followed by a linear regression to analyze the factors influencing the risk of suffering from ED. In addition, correlations were made to determine the relationship between the risk of manifesting ED and academic and sports performance. The main results show that 77.7% of the young athletes present a risk of ED (M = 13.3; DT = 3.33) due to a high body image distortion, which becomes the determining factor. In addition, relationships with family and friends have a significant influence on this. On the other hand, behaviors related with eating disorders affect concentration (r = -0.122; p = 0.01) and fatigue (r = -0.376; p < 0.01). For all these reasons, generating and promoting prevention and early detection guidelines during adolescence is necessary.

Body weight distortions in an auditory-driven body illusion in subclinical and clinical eating disorders

Previous studies suggest a stronger influence of visual signals on body image in individuals with eating disorders (EDs) than healthy controls; however, the influence of other exteroceptive sensory signals remains unclear. Here we used an illusion relying on auditory (exteroceptive) signals to manipulate body size/weight perceptions and investigated whether the mechanisms integrating sensory signals into body image are altered in subclinical and clinical EDs. Participants’ footstep sounds were altered to seem produced by lighter or heavier bodies. Across two experiments, we tested healthy women assigned to three groups based on self-reported Symptomatology of EDs (SED), and women with Anorexia Nervosa (AN), and used self-report, body-visualization, and behavioural (gait) measures. As with visual bodily illusions, we predicted stronger influence of auditory signals, leading to an enhanced body-weight illusion, in people with High-SED and AN. Unexpectedly, High-SED and AN participants displayed a gait typical of heavier bodies and a widest/heaviest visualized body in the ‘light’ footsteps condition. In contrast, Low-SED participants showed these patterns in the ‘heavy’ footsteps condition. Self-reports did not show group differences. The results of this pilot study suggest disturbances in the sensory integration mechanisms, rather than purely visually-driven body distortions, in subclinical/clinical EDs, opening opportunities for the development of novel diagnostic/therapeutic tools.

Hand size estimates of fibromyalgia patients are associated with clinical and experimental pain.

IntroductionSimply inspecting one’s own body can reduce clinical pain and magnification of body parts can increase analgesia. Thus, body perceptions seem to play an important role for analgesia. Conversely, pain may also affect bodily perceptions. Therefore, we evaluated the effects of clinical and/or experimental pain on perceived hand size in fibromyalgia patients (FM) and healthy controls (HC).MethodsTo investigate the effects of chronic and/or acute pain on size perception we compared hand size estimates of 35 HC and 32 FM patients at baseline and during tonic mechanical pain stimuli applied to one ear lobe. Mechanical stimuli were adjusted for each individual pain sensitivity to achieve a rating of 4 ± 1 VAS (0–10) units. Photographs of each subject’s hands were digitally manipulated to produce a monotonic series of 5 images larger and 6 smaller than actual size which were then presented to the participants in ascending and descending order (total number of images: 12).ResultsFM and HC participants’ clinical pain ratings at baseline were 3.3 (3.1) and .3 (.8) VAS units, respectively. At baseline, FM participants selected significantly smaller hand images than HC as representative of their actual size (p < .02). During application of tonic experimental pain, the image size chosen to represent their actual hand size decreased significantly in FM participants and HC (p < .001) but this decrease was not different between groups (p > .05). Hand size estimates of FM participants correlated negatively with their clinical pain ratings (p < .04).ConclusionThe decreased hand size perception of FM patients and HC was associated with their clinical and/or experimental pain, supporting the hypothesis that pain can result in visual body distortions.

Softer than soft: Diving into squishy granular matter

Softer than soft, squishy granular matter is composed of grains capable of significantly changing their shape (typically a deformation larger than 10%) without tearing or breaking. Because of the difficulty to test these materials experimentally and numerically, such a family of discrete systems remains largely ignored in the granular matter physics field despite being commonly found in nature and industry. Either from a numerical, experimental, or analytical point of view, the study of highly deformable granular matter involves several challenges covering, for instance: (i) the need to include a large diversity of grain rheology, (ii) the need to consider large material deformations, and (iii) analysis of the effects of large body distortion on the global scale. In this article, we propose a thorough definition of these squishy granular systems and we summarize the upcoming challenges in their study.

Body dissatisfaction among undergraduate medical students in the city of Juiz de Fora, Minas Gerais, Brazil.

ABSTRACTObjective To assess the level of body dissatisfaction among undergraduate medical students in the city of Juiz de Fora, Minas Gerais, Brazil.Methods A cross-sectional study with 232 volunteers of both sexes at a private college. The Body Shape Questionnaire was used, which is a tool based on the sum of values that allow classifying body dissatisfaction according to the following scores: less than 111, if absence of body dissatisfaction; between 111 and 138, if mild body dissatisfaction; between 139 and 167, if moderate body dissatisfaction, and from 168, if severe body dissatisfaction. In addition, the self-reported body mass index and an assertion were used to assess the degree and perception (insight) of body dissatisfaction. For the statistical analysis, descriptive comparison, and binary logistic regression tests were performed.Results The mean result of the Body Shape Questionnaire among women was 96.0±34.1 and among men, 76.7±24.7, with 26.3% of students with some level of dissatisfaction with self-image. Most participants (76.3%) wished to have a body mass index lower than the real one. Women (odds ratio of 5.7), overweight individuals (odds ratio of 6.1), and individuals with insight into their condition (odds ratio of 89.7) were more likely to be dissatisfied with the body image measured by the Body Shape Questionnaire.Conclusion The search for a thin body among undergraduate medical students is a reality. In addition to overweight individuals, the female population has a significant level of body distortion, being recognized as the highest rate of body dissatisfaction in the sample surveyed.

Intervention based on mindfulness and body image in patients undergoing bariatric surgery

After treatments for loss of large amounts of weight, the dissatisfaction with body image and the lack of recognition of the body itself is recurrent. These factors are elements of study due to the difficulties encountered in maintaining the results, in the long term, also in the surgical treatment of obesity. The lack of identity with the new form and dissatisfaction with body image have been pointed out as maintaining factors of poor eating habits and emotional eating that leads to weight recurrence. In this sense, the interest was raised as to whether: Would small mindfulness interventions have the ability to improve body image and favor the recognition of body distortions, in order to prevent weight recurrence in patients undergoing bariatric surgeries? This article aims to investigate the applicability of small mindfulness meditative strategies in the prevention of weight recurrence in bariatric patients. The method presented is a case report through 12 weekly meetings with a female client, 48 years of age, preoperative BMI of 42 Kg/m2 and postoperative BMI of 21.67 Kg/m2. The themes of the meetings were: psychoeducation about bariatric surgery, family approach, evaluation and psychoeducation about cognitive patterns, assessment of body image and body identity through photo composition. The other meetings were distributed among the small practices of mindfulness: breathing, movement, eating with mindfulness and body scanning. The practices demonstrated efficacy in reducing the discrepancy between the internal subjective perception of the body (interoception) and body image (exteroception). There was a positive experience of the body outside the aesthetic requirements, achievement of greater identity with body shape, exit from the perfectionist pattern and evaluation improvement of body shape and size. The small mindfulness-like meditative strategies have been shown to be effective in cognitive behavioral therapy for the prevention of weight recurrence in bariatric patients.

ELoriCorps Immersive Body Rating Scale and eLoriCorps Mobile Versions: Validation to Assess Body Image Disturbances from Allocentric and Egocentric Perspectives in a Nonclinical Sample of Adolescents.

A growing number of studies have used virtual reality (VR) for the assessment and treatment of body image disturbances (BIDs). This study, conducted in a community sample of adolescents, documents the convergent and discriminant validity between (a) the traditional paper-based Figure Rating Scale (paper-based FRS), (b) the VR-based Body Rating Scale (eLoriCorps-IBRS 1.1), and (c) the mobile app-based Body Rating Scale (eLoriCorps-IBRS 1.1-Mobile). A total of 93 adolescents (14 to 18 years old) participated in the study. Body dissatisfaction and body distortion were assessed through the paper-based FRS, the eLoriCorps-IBRS 1.1 and the eLoriCorps-IBRS 1.1-Mobile. Eating disorder symptoms, body image avoidance, and social physique anxiety were also measured. Correlation analyses were performed. Overall, the results showed a good and statistically significant convergence between allocentric perspectives as measured by the paper-based FRS, the eLoriCorps-IBRS 1.1 and the eLoriCorps-IBRS 1.1-Mobile. As expected, the egocentric perspective measured in VR produced different results from the allocentric perspective, and from cognitive–attitudinal–affective dimensions of BIDs, with the exception of body distortion. These differences support the discriminant validity of the egocentric perspective of eLoriCorps-IBRS 1.1 and are consistent with emerging evidence, highlighting a difference between experiencing the body from an egocentric (i.e., the body as a subject) and allocentric (i.e., the body as an object) perspective. The egocentric perspective could reflect a perceptual–sensory–affective construction of BIDs, whereas allocentric measures seem to be more related to a cognitive–affective–attitudinal construction of BIDs. Moreover, the results support the validity of the eLoriCorps-IBRS 1.1-Mobile with promising perspectives of implementation among young populations.

Green tea extract mediated biogenic synthesis of gold nanoparticles with potent anti-proliferative effect against PC-3 human prostate cancer cells

This study examines the biological synthesis of gold nanoparticles using Camellia sinensis L. (green tea) and their cytotoxicity against human PC-3 prostate cancer cells. The green tea extract-mediated biogenic synthesis of gold nanoparticles (GT-AuNPs) via green tea extract synthesis was validated using UV–vis spectroscopy, SEM, EDS, TEM, DLS, and XRD techniques. Additionally, the tetrazolium assay was utilized to investigate the anti-proliferative effect of GT-AuNPs generated by biosynthesis. The findings suggest that the biosynthesized GT-AuNPs reduced PC-3 cell proliferation with an IC50 of 19.71 g/mL during 24 h. These findings imply that GT-AuNPs exert their anti-proliferative action on the PC-3 cell line by inhibiting growth, decreasing DNA synthesis, and triggering apoptosis. After treatment, morphological examination of PC-3 cells exhibited surface detachment, cell shrinkage, and cell body distortion, indicating that GT-AuNPs had a cytotoxic effect on PC-3 cells.