ABSTRACT Body disposal methods complicate homicide investigations, obscuring links between both demographic factors and crime scene behaviors. This study is a comprehensive empirical assessment of offender and victim demographics, alongside crime scene behaviors, in relation to body disposal methods in homicides. This was done through the examination of 326 homicide cases involving 403 offenders and 334 victims through regression analyses. Key findings revealed significant associations between body disposal methods and factors such as victim gender, substance use by victims and offenders, and offenders’ prior sexual offense records. Additionally, the cause of death, location, and cleaning or destruction of evidence were predictive of disposal methods taking place. Notably, the presence of sexual elements appeared to influence only a small number of factors, being victim gender and crime scene cleaning. These results suggest enhanced investigative training on recognizing crime scene and victim characteristics may aid in refining investigative approaches and hypotheses. The findings also suggest that distinguishing between sexual and non-sexual homicides may not be crucial, allowing for more streamlined investigations and better resource allocation. This research advocates for interdisciplinary collaboration to improve investigative accuracy, highlighting the pivotal role of understanding the interconnectedness of behaviors in understanding body disposal.