Islamic boarding school institution is one of the oldest institutions in Indonesia, but its development is slower when it’s compared to other institutions. Researcher realizes that it is important to analyze the influence of organizational development, leadership and communication toward employee motivation, and its implication toward the teachers’ commitment at Islamic boarding school in Cilacap. To test the model and hypotheses, researcher uses the analysis of Structural Equation Model (SEM). Furthermore, to estimate the model, the author uses the program Analysis of Moment Structures (AMOS). Based on the research from Islamic boarding school teachers in Cilacap regency, it could be concluded that (1) organizational development, leadership, and communication give positive and significant impact on work motivation, either partially or simultaneously, (2) organizational development, leadership, communication, and work motivation give positive and significant impact on the commitment of Islamic boarding school teachers, either partially or simultaneously. Results of this study recommends that the commitment of Islamic boarding school teachers can be improved by motivating teachers in internal dimensions, especially those associated with the indicator in the form of an appreciation of their competences or scholarships.