BMJ Case Reports Research Articles

DIAGNOSING ACUTE COMPARTMENT SYNDROME

Compartment syndrome has been defined as “a condition in which increased pressure within a limited space compromises the circulation and function of the tissues within that space”.1 It is most commonly seen after injuries to the leg2-5 and forearm6-8 but may also occur in the arm,9 thigh,10 foot,11-13 buttock,14 hand15 and abdomen.16 It typically follows traumatic injury, but may also occur after ischaemic reperfusion injuries,17 burns,18 prolonged limb compression after drug overdose19 or poor positioning during surgery.20-24 Furthermore, subclinical compartment syndromes may explain the occurrence of a variety of postoperative disabilities which have been identified after the treatment of fractures of long bones using intramedullary nails.25 Approximately 40% of all acute compartment syndromes occur after fractures of the tibial shaft26 with an incidence in the range of 1% to 10%.26-30 A further 23% of compartment syndromes are caused by soft-tissue injuries with no fracture and fractures of the forearm account for 18%.26 Acute compartment syndrome is seen more commonly in younger patients, under 35 years of age31 and therefore leads to loss of function and long-term productivity in patients who would otherwise contribute to the country’s workforce for up to 40 years.

Reactivation of tuberculosis after total hip replacement

Reactivation of tuberculosis after total hip replacement

Side Effects of Metronidazole

Back to table of contents Previous article Next article ArticleNo AccessSide Effects of MetronidazoleA. JAMES GIANNINIA. JAMES GIANNINISearch for more papers by this authorPublished Online:1 Apr 2006https://doi.org/10.1176/ajp.134.3.329-dAboutSectionsPDF/EPUB ToolsAdd to favoritesDownload CitationsTrack Citations ShareShare onFacebookTwitterLinked InEmail "Side Effects of Metronidazole." American Journal of Psychiatry, 134(3), pp. 329-d–330 Access content To read the fulltext, please use one of the options below to sign in or purchase access. Personal login Institutional Login Sign in via OpenAthens Purchase Save for later Item saved, go to cart PPV Articles - American Journal of Psychiatry $35.00 Add to cart PPV Articles - American Journal of Psychiatry Checkout Please login/register if you wish to pair your device and check access availability. Not a subscriber? Subscribe Now / Learn More PsychiatryOnline subscription options offer access to the DSM-5 library, books, journals, CME, and patient resources. This all-in-one virtual library provides psychiatrists and mental health professionals with key resources for diagnosis, treatment, research, and professional development. Need more help? PsychiatryOnline Customer Service may be reached by emailing [email protected] or by calling 800-368-5777 (in the U.S.) or 703-907-7322 (outside the U.S.). FiguresReferencesCited byDetailsCited byMetronidazole-associated Neurologic Events: A Nested Case-control Study18 April 2020 | Clinical Infectious Diseases, Vol. 72, No. 12Metronidazole-induced reversible cerebellar dysfunction1 February 2021 | BMJ Case Reports, Vol. 14, No. 2Annals of Neurology, Vol. 76, No. 4Mental Health Clinician, Vol. 3, No. 5Metronidazole-Induced Central Nervous System ToxicityClinical Neuropharmacology, Vol. 34, No. 6Psiquiatría Biológica, Vol. 17, No. 2Psychosomatics, Vol. 34, No. 3British Journal of Psychiatry, Vol. 154, No. 4American Journal of Obstetrics and Gynecology, Vol. 145, No. 5Metronidazole and Alcohol–Potential for Combinative Abuse25 September 2008 | Journal of Toxicology: Clinical Toxicology, Vol. 20, No. 5The Lancet, Vol. 310, No. 8052 Volume 134Issue 3 March 1977Pages 329-d-330 Metrics PDF download History Published online 1 April 2006 Published in print 1 March 1977

Cardiac output in athletes.

Cardiac output in athletes.

Respiratory bronchioles as the pathway for collateral ventilation.

Respiratory bronchioles as the pathway for collateral ventilation.

Effect of mean circulatory filling pressure and other peripheral circulatory factors on cardiac output.

I P ONE studies curves which depict the relationship of cardiac output to mean right atria1 pressure (one of the forms of Starling’s curves), it is obvious that, within the normal range of function of the heart, cardiac output can change tremendously while the right atria1 pressure changes only slightly. This fact led to the early belief that it is not the function of the heart itself which controls cardiac output but instead that cardiac output is controlled by the various factors in the peripheral circulatory system which regulate the return of blood to the heart. Though it is not entirely true that cardiac output is independent of the function of the heart (I), nevertheless, it is hoped to emphasize in the present paper the special importance of the peripheral circulatory factors which affect venous return. In order to do this, a mathematical circuit analysis of the closed circuit circulatory system has been made. This circuit analysis has been specifically simplified so that the factors derived would be amenable to experimental test. Two of the factors which have proved to be of importance, as shown both by this circuit analysis and by experimental data, are a) ‘capacitance’ and b) ‘mean circulatory filling pressure.’ As used in these studies the term capacitance means dV/dP or, in other words, the change in volume of a particular part of the circulatory system with each unit change in pressure. This term has been used in the present paper because there is at present no term in common usage in hydrodynamics which means dV/dP. This is different from the term ‘distensibility’ which is commonly used to mean dV/dP + V. The term mean circulatory filling pressure (MCFP) has been defined previously (2), and it means ,__-