Blood Pressure In Hypertensive Adults Research Articles

Dietary adherence and associated factors among hypertensive patients in governmental hospitals of Guji zone, Oromia, Ethiopia

BackgroundThe Dietary Approaches to Stop Hypertension (DASH) diet has been shown to reduce blood pressure in hypertensive adults, but there is limited information available on dietary adherence and related factors among hypertensive patients in the study area. Hence, the current study aimed to assess dietary adherence and associated factors among hypertensive patients aged greater than or equal to 18 years old in governmental hospitals of Guji zone, Oromia region, Ethiopia.MethodsA facility-based cross-sectional study was conducted between June 5, 2023, and August 30, 2023. For this study, patients with a systolic blood pressure of 140 mmHg or higher and/or a diastolic blood pressure of 90 mmHg or higher on two separate occasions were classified as hypertensive. Thus, the study involved 399 hypertensive patients who were selected using systematic random sampling methods. The level of knowledge regarding hypertension was measured through the use of hypertension knowledge-level scale (HK-LS) questionnaires, while the reliability and validity of the questionnaire were assessed using the Cronbach’s alpha test (α ≥ 0.70).The association between factors was analyzed using adjusted odds ratio (AOR) and a 95% confidence interval. Variables with p-values below 0.05 were considered statistically significant.ResultsAmong the respondents, only 28.30% (CI: 23.9, 33) of participants were found to be adherent to the recommended diet. Factors like participation in nutritional education, level of knowledge, respondents’ ages, and length of time since hypertension diagnosis showed a strong association with adherence to recommended dietary guidelines.ConclusionsThe research findings indicated that the level of compliance with the prescribed diet was generally subpar among individuals with hypertension in comparison to the Dietary Approaches to Stop Hypertension (DASH) diet recommendations. So, it is essential to offer hypertensive patients an education focused on health and nutrition in order to enhance their adherence to dietary guidelines and promote a healthier dietary routine. The results of this research will also be valuable in increasing awareness among policymakers and the general public about the dietary adherence and its associated factors, thus aiding in the development and execution of suitable interventions.

Randomized Trial of Nitrate-Replete Beetroot Juice on Blood Pressure in Hypertensive Adults with ADPKD

Randomized Trial of Nitrate-Replete Beetroot Juice on Blood Pressure in Hypertensive Adults with ADPKD

Oral hygiene and periodontal treatment interventions for reducing blood pressure in hypertensive adults from low and middle-income countries: a systematic review

Oral hygiene and periodontal treatment interventions for reducing blood pressure in hypertensive adults from low and middle-income countries: a systematic review

Efficacy of beetroot juice on reducing blood pressure in hypertensive adults with autosomal dominant polycystic kidney disease (BEET-PKD): study protocol for a double-blind, randomised, placebo-controlled trial

BackgroundIn autosomal dominant polycystic kidney disease (ADPKD) impaired nitric oxide (NO) synthesis, in part, contributes to early-onset hypertension. Beetroot juice (BRJ) reduces blood pressure (BP) by increasing NO-mediated vasodilation. The aim of this double-blind, randomised, placebo-controlled study is to test the hypothesis that BRJ reduces systolic and diastolic clinic BP in hypertensive adults with ADPKD.MethodsParticipants with ADPKD and treated hypertension (n = 60) will be randomly allocated (1:1) to receive a daily dose of either nitrate-replete (400 mg nitrate/day) or nitrate-deplete BRJ for 4 weeks. The co-primary outcomes are change in mean systolic and diastolic clinic BP before and after 4 weeks of treatment with daily BRJ. Secondary outcomes are changes in daily home BP, urinary albumin to creatinine ratio, serum and salivary nitrate/nitrite levels and serum asymmetric dimethylarginine levels before and after 4 weeks of BRJ.DiscussionThe effect of BRJ in ADPKD has not been previously tested. BRJ is an accessible, natural dietary supplement that, if effective, will provide a novel adjunctive approach for treating hypertension in ADPKD.Trial registrationClinicalTrials.gov NCT05401409. Retrospectively registered on 27th May 2022.

ADHERENCE TO TREATMENT IN HYPERTENSIVE ADULTS: RELATIONSHIP WITH SOCIAL SUPPORT, ANXIETY AND DEPRESSION

Objective: This study examined the relationship between Social Support (SS) Anxiety (A) Depressión (D) with adherence to treatment (AT) in hypertensive adults. Design and method: There were 1582 hypertensive adults, males (n = 404) and females (n = 1178), age mean = 72 years, (SD = 12, 57). The Morisky–Green test evaluated compliant and non-compliant, DUKE test evaluated affective social support (ASS) and confidential social support (CSS), Zung Anxiety scale: Minimum anxiety (MiA), Moderate anxiety MoA) and Severe anxiety (SeA) and Zung Depression scale: Non depression (NoD) Minimum Depression (MiD) and Moderate- Severe Depression (MosD), all applied in one day doctor's visit. Results: The means and standard deviations for Systolic Blood Pressure of hypertensive adults was: 158,91 ± 29,82; for Diastolic Blood Pressure of hypertensive adults was 74,43 ± 12,79. Hypertensive adults compliant 20,3% and hypertensive adults non-compliant 79,7%. Good ASS support was 4.1%; bad ASS was 95.9%. Good CSS was 3.4% and 96.6% for bad CSS. MiA 35.6%; MoA 30% and SeA 34.4%. NoD 29.3%; MiD 63.7% and MosD 7%. The Rho Spearman correlation showed a significant correlation between AT and ASS (Rho Spearman: r = ,120**/ p = ,000); AT and CSS (Rho Spearman: r = ,113**/ p = ,000); AT and A (Rho Spearman: r = ,141**/ p = ,000); AT and D (Rho Spearman: r = ,132**/ p = ,000). Conclusions: The results provide evidence of a relationship between AT and ASS, CSS, A, D in hypertensive adults, indicating that social support and mood are important variables that must be evaluated when measuring adherence to treatment and seeking strategies to improve them.

JS-NG-6: FRESH START: A LIFESTYLE INTERVENTION APPROACH IN REVERSING HYPERTENSION

Objective: Approximately 1.13 billion people worldwide are hypertensives, and they are mostly living in low- and middle-income countries. In the Philippines, one in five Filipinos are hypertensive and less than 20% of these hypertensives have controlled blood pressure of less than 140mmHg/90mmHg. Lifestyle intervention approaches in the primary level of prevention are not common. This study determined the effect of an eight-week, pure lifestyle intervention approach with the use of proper nutrition, physical activity, stress management, among others, in the blood pressure of hypertensive adults living in a rural community setting. Design and method: There were two phases of the study. The first phase was a needs assessment survey among 58 respondents to determine knowledge, attitude, preventive practices regarding hypertension and risks of high blood pressure. The second phase was an intervention program among those who qualified through purposive sampling with the following criteria: 1. Diagnosed as Stage 1 Hypertension according to the 2017 guideline, 2. willing to participate. A module entitled Fresh Start was created and was used as a guide in conducting the lifestyle intervention which lasted for eight weeks. Results: We utilized descriptive and repeated measures (week 1, 4 and 8, respectively) to analyse the result; 72% have good knowledge, good attitude (mean-3.47) and good hypertensive practices practice (3.44). Via Friedman test, there was a significant difference in systolic pressure across the given three periods of time, p < 0.001. Post hoc analysis with Wilcoxon signed-rank tests showed a significance level, p < 0.025. There is a significant difference from week 1 to week 4 (Z = -2.085, p = 0.005) and a significant difference from week 4 to week 8 (Z = -2.549, p = 0.001). Further, there was a statistically significant difference in diastolic pressure across the given three periods of time, p = 0.002. Post hoc analysis with Wilcoxon signed-rank tests resulted in a significance level set at p < 0.025. There is no significant difference from week 1 to week 4 (Z = -2.018, p = 0.044) but there is a significant difference from week 4 to week 8 (Z = -2.521, p = 0.012). Conclusion: This study revealed that lifestyle intervention approach to decrease blood pressure in a community setting is possible. As incidence of high blood pressure increase, especially among the poor socio-economic status spectrum, there is a need of new preventive measures that will address such needs.

Effect of oral l-arginine supplementation on post-exercise blood pressure in hypertensive adults: A systematic review with meta-analysis of randomized double-blind, placebo-controlled studies

We studied the effects of oral L-arginine on post-exercise blood pressure (BP). Throughout October 2020 and February 2021, the electronic databases Medline, Web of Science, CINAHL, Embase, Cochrane, Bireme, Open Gray, MedRxiv, Clinical Trials and Scopus were considered. The terms enforced to search randomized, double-blind and placebo-controlled clinical trials were, “Arginine” AND “Post-exercise”. Three studies were involved in the meta-analysis, the original results of the three studies demonstrated a trend related to L-arginine intervention. The 95% CI ranged from −7.94 to −2.14 with a combined effect size of −5.04 for systolic BP and −4.96 to −0.97 with a combined effect size of −2.96 for diastolic BP. Our meta-analysis revealed a combined effect size of 3.40 ( P = 0.0007) for systolic BP and 2.91 ( P = 0.004) for diastolic BP supportive of L-arginine intervention. Our review delivers evidence that oral L-arginine supplementation has the potential to reduce post-exercise systolic and diastolic BP in hypertensive patients. Nous avons évalué les effets de la L-arginine orale sur la tension artérielle après l’exercice. Tout au long d’octobre 2020 et février 2021, les bases de données électroniques Medline, Web of Science, CINAHL, Embase, Cochrane, Bireme, Open Gray, MedRxiv, Clinical Trials et Scopus ont été étudiées. Les termes utilisés pour rechercher des essais cliniques randomisés, en double aveugle et contrôlés par placebo étaient «Arginine» ET «Post-exercice». Trois études ont été impliquées dans la méta-analyse, les résultats originaux des trois études ont démontré une tendance liée à l’intervention avec la L-arginine. L’IC à 95 % variait de −7,94 à −2,14 avec une taille d’effet combiné de −5,04 pour la PA systolique et de −4,96 à −0,97 avec une taille d’effet combiné de −2, 96 pour la PA diastolique. Notre méta-analyse a révélé une taille d’effet combiné de 3,40 ( p = 0,0007) pour la tension artérielle systolique et de 2,91 ( p = 0,004) pour la tension artérielle diastolique en faveur d’une intervention avec la L-arginine. Notre revue fournit des preuves que la supplémentation orale en L-arginine a le potentiel de réduire la tension artérielle systolique et diastolique post-exercice chez les patients hypertendus.

WORK-BASED ISOMETRIC EXERCISES EFFECT ON BLOOD PRESSURE: THE EEFIT STUDY

Objective: To evaluate the effect of two workplace isometric exercise interventions on blood pressure in hypertensive adults. Design and method: A randomized controlled multicenter clinical trial conducted in hypertensive (>130 mmHg systolic blood pressure (SBP)) 35 to 65 years old in work places in Colombia. Participants were assigned to either of two interventions: isometric handgrip dynamometer training at 30% of maximum strength (HGD) or wall squat (WS), or to a control group following standard recommendations. The interventions were performed at the participant’s workplace and consisted of 4 sets of 2 minutes of sustained isometric contraction with 2 minutes’ rest between sets, 3 times per week for 12 weeks. SBP and diastolic blood pressure (DBP) were measured using an automatic device (Omron) with a standardized protocol before and after the 12-week intervention. Results: Pre and post measurements were completed by 105 hypertensive participants: mean age of 45 years (SD 9.5), 63.8% of which were men. In the HGD group (n = 38) there were significant decreases in SBP [Pre: 141 mmHg (SD 7.8), Post: 127 mmHg (SD 9.1) (p < 0.001)], and in DBP [Pre: 87 mmHg (SD 5.8), Post: 82 mmHg (SD 9.5) (p < 0.001)]. There were also significant decreases in the WS-group (n = 35) in SBP [Pre: 139 mmHg (SD 7.5), Post: 126 mmHg (SD 12.4) (p < 0.001)], and in DBP [Pre: 86 mmHg (SD 5.2), Post 82 mmHg (SD 8.1) (p < 0.001)]. In the control group (n = 32), there were no significant changes in either in SBP [Pre: 140 mmHg (SD 8.4), Post: 137 mmHg (SD 12.9)], or DBP [Pre: 86 mmHg (SD 5.0), Post: 85 mmHg (SD 8.0) (p = 0.71)]. Conclusions: Both workplace isometric training interventions resulted in significant and clinically relevant reductions in blood pressure in subjects with high blood pressure. The combination of effectiveness, modest time commitment (42 minutes per week) and ease with which the interventions can be implemented in the workplace setting makes them both attractive and practical options with minimal barriers for participation. Furthermore, WS can be performed without any equipment.

Effects of Differences in Exercise Programs With Regular Resistance Training on Resting Blood Pressure in Hypertensive Adults: A Systematic Review and Meta-Analysis.

Igarashi, Y. Effects of differences in exercise programs with regular resistance training on resting blood pressure in hypertensive adults: A systematic review and meta-analysis. J Strength Cond Res 37(1): 253-263, 2023-This systematic review and meta-analysis aimed to evaluate changes in resting blood pressure (RBP) with differences in regular resistance training (RT) programs. Inclusion criteria were randomized controlled trials involving hypertensive adults and interventions involving only RT of both the upper and lower limbs for ≥7 weeks. The weighted mean difference (WMD) was defined as the mean difference between the exercise and control groups, weighted by the inverse of the squared standard error for each study, and all WMDs in RBP were pooled as overall effects. A simple meta-regression analysis was performed to evaluate the relationship between RT variables (percentage 1 repetition maximum [1RM], number of repetitions, number of sets, and weekly frequency) and changes in RBP. Seventeen studies (646 subjects) were analyzed. The pooled WMDs in the resting systolic blood pressure (RSBP) and resting diastolic blood pressure (RDBP) decreased significantly but contained significant heterogeneity {RSBP, -4.7 mm Hg (95% confidence interval [CI], -6.7 to -2.8; I2 = 46.6%); RDBP, -3.5 mm Hg (95% CI, -4.9 to -2.1; I2 = 39.1%)}. Meta-regression analysis revealed that an increase in % 1RM was significantly associated with a decrease in the RSBP (γ = -0.25x 0 + 10.85, where γ represents the mean difference in RSBP, and x 0 represents % 1RM [%]), and heterogeneity was alleviated ( I2 = 0.0%). For reducing RSBP, regular RT with moderate or heavy loads may be more beneficial than regular RT with light loads.

Effects of Isometric Biceps Exercise on Blood Pressure in Adults with Hypertension

We investigated the acute effects of isometric biceps exercise on resting and ambulatory blood pressure in hypertensive adults. A total of 12 medicated hypertensive adults (aged 47±7 years; body mass index 27.2±2.7 kg/m2; resting blood pressure 123±12/74±6 mmHg) performed an isometric biceps exercise session (bilateral biceps exercise; 4×1 min at 30% of 1-RM, 2 min recovery) and a control session (without exercise) in a randomized order separated by a 7 to 10-day period. Resting blood pressure, heart rate, and heart rate variability indexes (SDNN, RMSSD, LF, HF, and LF/HF) were measured pre- and up to 30 min post-sessions. Next, ambulatory blood pressure was monitored during 22-hour post-sessions (awake and asleep periods). No significant changes were observed for resting blood pressure, heart rate, or heart rate variability indexes up to 30 min post-sessions (p>0.05). Furthermore, no significant differences were observed in average ambulatory blood pressure values in 22-hour (126±11/71±6 mmHg vs. 126±15/71±9 mmHg), awake (127±10/74±6 mmHg vs. 130±14/75±10 mmHg), and asleep (123±15/68±6 mmHg vs. 120±17/66±9 mmHg) periods between the control and isometric sessions, respectively (p>0.05). In conclusion, an isometric biceps exercise session does not elicit an acute antihypertensive effect in adults with hypertension, which suggests that its prescription to improve the acute BP control is limited.

Effect of probiotic foods and supplements on blood pressure: a systematic review of meta-analyses studies of controlled trials.

Recent evidences suggested that hypertension was associated with changes in gut microbiota composition. As intervention with probiotics might be considered as one of the approaches for modulating gut microbiota, the objective of the present study was to systematically review the meta-analyses of controlled trials (CTs) to elucidate the effects of probiotics on blood pressure. We searched PubMed, Web of Science, and Cochrane Library databases until November 2019 to explore all the meta-analyses conducted on the CTs assessing the efficacy of probiotics in the management of blood pressure (BP). Meta-analyses performed on in vitro, animal or observational studies were excluded from the study. References of the included studies were also screened to obtain further eligible publications. From the 111 records which were identified during the literature search, 5 meta-analyses met the selection criteria. Total sample size was 2703 subjects (1009 subjects with type 2 diabetes mellitus (T2DM)), aged 12-75 years from both sexes. Results of meta-analyses have been shown a moderate effect of probiotics on BP in hypertensive adults with/without T2DM; from 3.10 to 5.04 mmHg for systolic blood pressure (SBP) and from 0.39 to 3.84 mmHg for diastolic blood pressure (DBP) after 3-24 weeks consumption. These effects were greater in adults with BP ≥ 130/85, by dairy products, by Asian fermented products with multiple species and higher dose of probiotics (≥ 1011 colony forming units (CFU)). It seems probiotic foods and supplements which were contained high dose multiple species of probiotic bacteria could be more effective in BP control.

Effectiveness of physical activity in the prevention and treatment of hypertension: A mini review

Physical activity (PA) is associated with a clear decrease in blood pressure (BP) and cardiovascular mortality in both men and women. The aim of this review was to evaluate the effectiveness of PA as an adjunct therapy in support of the prevention and pharmacological treatment of hypertension. Studies that reported on the correlation of PA and exercise on BP control among hypertensive patients from 1994 to 2019 were evaluated. PubMed electronic database was utilized. The MeSH system was used to extract relevant research studies from PubMed using the following keywords: “Exercise,” “training,” “hypertension,” “blood pressure,” “systematic review,” and “meta-analysis,” All selected articles were published in English. Sedentariness negatively affects cardiometabolic health, body composition, and BP among hypertensive patients, whereas PA significantly improves cardiometabolic parameters and body composition and leads to an overall improvement in cardiac parasympathetic system by increasing vagal tone, causing a reduction in resting heart rate, and systolic BP in hypertensive adults. Exercise should be tailored according to patient's clinical and functional status to avoid imposing variable internal training load on the patients. Moderate intensity aerobic, isometric and dynamic resistance exercise training alone, or a combination was equally effective in lowering BP among hypertensive adults.

Isometric Exercise with Large Muscle Mass Improves Redox Balance and Blood Pressure in Hypertensive Adults.

The aim of this study was to investigate the hemodynamic, oxidative stress (OS), and nitric oxide (NO) responses to a submaximal isometric exercise session (IES) involving large muscle mass. Fourteen hypertensive (HTG: age = 35.9 ± 8.1 yr, height = 1.73 ± 0.10 m, total body mass = 78.0 ± 15.8 kg) and 10 normotensive (NTG: age = 41.1 ± 9.4 yr, height = 1.71 ± 0.12 m, total body mass = 82.3 ± 22.4 kg) participants performed two experimental sessions in the leg press and bench press: (i) control session and (ii) 8 sets × 1 min contraction at 30% maximal voluntary isometric contraction with 2-min rest interval. Blood pressure (BP) was measured at rest and during 60 min postexercise. Blood samples were collected at rest, immediately after the session, and 60 min postexercise. NO was obtained through the Griess reaction method. OS parameters were analyzed using commercial kits. A repeated-measures ANOVA with Bonferroni post hoc test was used to analyze all dependent variables. A significant decrease in systolic BP was observed only for HTG at 45 and 60 min postexercise (baseline vs 45 min: P = 0.03, Δ% = 4.44%; vs 60 min: P = 0.018, Δ% = 5.58%). NO increased immediately postexercise only for HTG (P = 0.008, Δ% = 16.44%). Regarding OS parameters, thiobarbituric acid reactive substances presented a significant reduction 60 min after the IES for NTG and HTG; catalase increased in both groups. The data showed that only 8 min of IES with a large muscle mass elicits an elevated pro-oxidant activity leading to a greater NO bioavailability, increases antioxidant reaction, and consequently reduces BP in hypertensive patients.

Effectiveness of dietary inorganic nitrate for lowering blood pressure in hypertensive adults: a systematic review.

The objective of this review was to evaluate the effectiveness of inorganic nitrate on blood pressure in hypertensive adults. Hypertension is associated with increased risk of morbidity and mortality in adults. Inorganic nitrate could be beneficial for lowering blood pressure and reducing cardiovascular disease risks. Evidence related to the treatment of hypertension through sources of inorganic nitrate has been presented. The review considered studies on adults aged 18 years and over, with blood pressure greater than 120/80 mmHg, undergoing interventions focusing on the effects of inorganic nitrate on blood pressure. Studies that included inorganic nitrate intake via dietary modification, in the form of a dietary supplement, and/or by the consumption of beetroot juice were considered. The comparator was no intervention of inorganic nitrate; different dosage, frequency, duration of inorganic nitrate; and other interventions that are administered to reduce and manage blood pressure. The primary outcomes were systolic and diastolic blood pressure effects. Experimental, quasi-experimental, analytical observational and pilot study designs were considered for inclusion. Databases were searched for published and unpublished studies, available in English, from January 2013 to January 2018. Critical appraisal was conducted using standardized instruments from the Joanna Briggs Institute (JBI) and the methodological quality of included studies was considered to be moderate. Data were extracted using the JBI data extraction instrument. Data were presented in a narrative form due to the heterogeneity of included studies. Twelve papers were included in the systematic review with a total of 321 participants. Ten were randomized controlled trials and two were quasi-experimental studies. All participants had baseline blood pressures greater than 120/80 mmHg. Some studies included participants with comorbidities such as diabetes or heart failure with preserved ejection fraction. Inorganic nitrate was administered multiple ways throughout the studies including the following: beetroot juice, beetroot gel, nitric oxide lozenge, high nitrate diet, and raw and cooked beet juice. Doses and treatment intervals varied. Some studies included exercise as part of the intervention protocol.Meta-analysis was not conducted due to heterogeneity that existed within the studies. Blood pressure was measured in multiple settings by manual, digital or ambulatory means. The noted outcome patterns were as follows: no change in systolic blood pressure and diastolic blood pressure, decrease in systolic blood pressure and diastolic blood pressure, or decrease in systolic blood pressure with no change in diastolic blood pressure. Possible reasons for the diverse findings include the following: age, comorbidities, use of antihypertensives by participants; source and dose of nitrate; and intervention and follow-up time frames. There is insufficient evidence to support or refute the use of inorganic nitrate for any effect on blood pressure at this time. Therefore, there is no concrete base for the development of practice guidelines until stronger evidence becomes available. The gaps in the literature along with the study limitations identified necessitate the need for more research on inorganic nitrate and how it relates to blood pressure.

Determinants of Blood Pressure Control and Prevalence of Hypertension in Adults in 2017: A Population-Based Study in West Jakarta

Background:The high prevalence of hypertension in developing countries underlines the need for accurate data on the prevalence of adult hypertension, as well as patient characteristics and determinants of blood pressure control. As this information is currently not available, our aim was to collect such data from a population of patients in the Tegal Alur Administrative Village, West Jakarta Indonesia.Objective:We conducted a case-control study (n = 152) to identify determinants of hypertension and a cross-sectional study (n = 3842) to determine hypertension prevalence and investigate determinants of blood pressure control in hypertensive adults (≥18 years old).Methods:The cross-sectional design involved the diagnosis of hypertension via home visits (active detection) and routine clinical examinations at the Tegal Alur II Community Health Center (passive detection). In the case-control design, the groups were sex-matched.Results:In 2017, the prevalence of hypertension in adults in Tegal Alur was 16.8% (n = 646), and the rate of uncontrolled hypertension was 89% (n = 572). A multivariate analysis showed that the adjusted prevalence ratio for comorbidities was 2.1 (95% confidence interval [CI]: 1.48–3.12;p= 0.005). A body mass index indicative of being overweight (≥23 kg/m2) had an odds ratio of 2.25 (95% CI: 1.14–4.44;p= 0.016).Conclusion:Comorbidities were the strongest predictor of uncontrolled blood pressure in hypertensive adults of Tegal Alur. Being overweight (BMI ≥23 kg/m2) was significantly associated with hypertension.

Association between subjective sleep duration on workdays or non-workdays and uncontrolled blood pressure in Southern China

ObjectivesTo examine the association between sleep duration on workdays or non-workdays and unsatisfactory blood pressure (BP) control in Southern China. MethodsWe analyzed 4370 hypertensive patients, including their self-reported sleep duration on workdays or non-workdays and their BP. Unsatisfactory BP control was defined as systolic BP of ≥140 mm Hg or diastolic BP of ≥90 mm Hg. Multivariate logistic regression analyses were performed to evaluate the association between sleep duration and unsatisfactory BP control. ResultsOverall, the multivariable-adjusted odds ratios of unsatisfactory BP control risk were 1.59 (95% confidence interval, 1.14–2.22) for 9–10 hours of sleep on workdays and 1.47 (95% confidence interval, 1.07–2.03) for ≥10 hours of sleep on non-workdays compared with a sleep duration of 5–9 hours. No association between a short sleep duration and unsatisfactory BP control was noted. The association between a longer sleep duration (≥10 hours) and unsatisfactory BP control was more pronounced among women aged 65–70 years, with a body mass index ≥ 24 kg/m2. ConclusionPeople with hypertension who slept 9–10 hours on workdays and ≥10 hours on non-workdays were more likely to have unsatisfactory BP control compared with those with a sleep duration of 5–9 hours; these associations tended to vary by age, sex, and body mass index. These findings indicate that a longer sleep duration might be a way to predict uncontrolled BP in hypertensive adults.

Effect of structured physical activity on blood pressure among hypertensive adults attending the general out-patient clinic and medical out-patient clinic of Aminu Kano Teaching Hospital, Kano, Nigeria

Introduction: hypertension is a major public health problem because of its rising prevalence worldwide. Globally, prevalence of hypertension in adults was around 22% in 2014. In Africa, a systematic review in 2014 reported a prevalence of 19.7% in 1990, 27.4% in 2000 and 30.8% in 2010. Similarly, in northern Nigeria, the prevalence of hypertension was 32.3% and 39.1% in Maiduguri and Kano respectively. This high prevalence of hypertension prompts primary prevention with lifestyle modification such as increased physical activity. This study aims to determine the effect of structured physical activity on blood pressure of hypertensive adults attending GOPC and MOPC at Aminu Kano Teaching Hospital (AKTH), Kano.

Effectiveness of dietary inorganic nitrate in lowering blood pressure in hypertensive adults: a systematic review protocol.

The question of this review is: what is the effect of dietary inorganic nitrate on blood pressure in adults with blood pressure >120/80mmHg?

Effect of lysine supplementation on hypertensive men and women in selected peri-urban community in Ghana

BackgroundLysine is one of the essential amino acids and in cereal based diets it is known to be the most limiting and therefore determines the quality of dietary protein in such diets. This study investigated the effect of lysine supplementation on blood pressure of hypertensive adults in selected peri-urban community in Accra, Ghana.MethodsThe study was a randomized double-blind controlled study made up of adults men and women assigned to a lysine supplemented group and a placebo-supplemented (control) group. The subjects aged between 18 – 45 years and totaling 180.ResultsTotal of 50 (28%) of the participating were hypertensive defined as Systolic Blood Pressure (SBP) ≥140 mmHg. The mean SBP of lysine-supplemented group significantly dropped from 146.11 ± 11.92 to 128.95 ± 10.44 mmHg (p = 0.02). That of women also dropped from 144.12 ± 10.41 to 132.28 ± 10.69 mmHg, (p = 0.06 while the control group had there SBP remained fairly constant after 112 days of intervention with changes in men from 145.79 ± 12.56 to 142.79 ± 11.07 mmHg (p = 0.32) and women in the control had very little drop from 145.15 ± 14.79 to 145.00 ± 17.93 mmHg (p = 0.96).ConclusionLysine supplementation resulted in normalization/reduction of blood pressure of hypertensive subjects who have suboptimal lysine intake.

Concord grape juice, cognitive function, and driving performance: a 12-wk, placebo-controlled, randomized crossover trial in mothers of preteen children

AbstractBackground: Daily consumption of Concord grape juice (CGJ) over 3–4 mo has been shown to improve memory function in adults with mild cognitive impairment and reduce blood pressure in hypertensive adults. These benefits likely result from the high concentration of polyphenols in CGJ. Increased stress can impair cognitive function and elevate blood pressure. Thus, we examined the potential beneficial effect of CGJ in individuals with somewhat stressful and demanding lifestyles.Objective: We sought to examine the effects of the daily consumption of CGJ for 12 wk on cognitive function, driving performance, and blood pressure in healthy, middle-aged working mothers.Design: Twenty-five healthy mothers (aged 40–50 y) of preteen children who were employed for ≥30 h/wk consumed 12 ounces (355 mL) of either CGJ (containing 777 mg total polyphenols) or an energy-, taste-, and appearance-matched placebo daily for 12 wk according to a randomized crossover design with a 4-wk washout. Verbal and spatial memory, executive function, attention, blood pressure, and mood were assessed at baseline and at 6 and 12 wk. Immediately after the cognitive battery, a subsample of 17 women completed a driving performance assessment at the University of Leeds Driving Simulator. The 25-min driving task required participants to match the speed and direction of a lead vehicle.Results: Significant improvements in immediate spatial memory and driving performance were observed after CGJ relative to placebo. There was evidence of an enduring effect of CGJ such that participants who received CGJ in arm 1 maintained better performance in the placebo arm.Conclusions: Cognitive benefits associated with the long-term consumption of flavonoid-rich grape juice are not exclusive to adults with mild cognitive impairment. Moreover, these cognitive benefits are apparent in complex everyday tasks such as driving. Effects may persist beyond the cessation of flavonoid consumption, and future studies should carefully consider the length of washout within crossover designs. This trial was registered at clinicaltrials.gov as NCT01411631.