Introduction. The investigation contains a scientific development of some concepts and categories from the interstate regulation of the procedures for the introduction of digital technologies in Industry 4.0 for their use by economic entities of the EAEU and BRICS jurisdictions in their foreign economic activities. The definition of legal risks that may arise during the implementation and application of digital technologies of Industry 4.0 formulated at the conceptual level.Materials and methods. The work used traditional general scientific research methods, such as the dialectical method of cognition, analysis, synthesis, induction, deduction, as well as private scientific legal methods, including formal legal, the method of legal interpretation. The authors implement a systematic approach to the study of the problem by using several methods of scientific research in combination. Research results. As a result of the analysis, the authors substantiate the scientific and methodological principle of inter-jurisdictional risk management of changes in legislation, as well as their neutralization and avoidance in the implementation of foreign economic activity by economic entities of the EAEU and BRICS jurisdictions. This approach of inter-jurisdictional management of legal risks proposed to be enshrined in the provisions of the international convention, to which the countries participating in integration associations will be able to join, ensuring the entry into force of the relevant regulatory provisions in their jurisdictions.Discussion and conclusion. Based on the results of the study, a complex of information and communication technologies for continuous tracking of the movement of individual goods, as well as vehicles that transport goods under foreign trade transactions between the jurisdictions of the EAEU and BRICS associations, has been formed in five categories. This set of digital technologies applied on basis of a new scientific and methodological approach to inter-jurisdictional risk management of collisions with legal provisions, as well as the neutralization and avoidance of these risks in the implementation of foreign economic activities by economic entities of the jurisdictions of these associations.The new approach provides for the coordination of the regulatory documents adopted by the member states of the integration associations in the mechanism of the inter-jurisdictional polysubject blockchain. The documents relate to the introduction and application of digital technologies of foreign economic activity, to the level of a single (identical) regulatory document for all participants by simultaneously registering it on the server of each of the foreign economic departments of the EAEU and BRICS as subjects of a distributed register.