Abstract Background Digital health (DH) presents vast opportunities, but also dynamic shift in viewpoints, which is reflected in academic works. Since DH concerns patient data, a major issue is complying with the bioethical principles, and ensuring patients’ privacy and security. The aim of this research is to explore avenues, in which ethics and privacy are reflected in DH, especially in terms of research, legislation, artificial intelligence (AI) and blockchain applications in medicine and public health. Methods Literature search for full text publications in PubMed, Scopus and ScienceDirect focused on ethics and privacy in DH in the period 2019-2023 found 325 articles in English authored by academicians. Six thematic categories were identified: ethics (fundamental principles; ethics in using novel DH tools); privacy (in use of apps/wearables; as a challenge/barrier to DH interventions/technologies); ethics/privacy in: DH research (data gathering, use, sharing); policy and legislation (for DH applications); AI and blockchains (in medicine and public health). Results Articles were from 32 countries: USA-24.3%; UK-13.5%; Germany-7.7%; Canada-7.4%; Australia-6.7%; Netherlands, Italy, Switzerland-4.7% each; China, India-3.0% each and 20.3% from 22 other countries; 86.5% in medical/DH journals. Only 10.2% were published in 2019; 17.8% - 2020; 19.4% - 2021; 27.1% - 2022 and 25.5% - 2023. Privacy was discussed in 26.5%; ethics-23.7%; research-19.4%; AI-15.1%; policy and legislation-9.5% and blockchains-5.5% of the articles. The publication activity of all six categories increased after the unfold of the pandemic in 2020. In 2023 publications for ethics (13%), privacy (5.8%) and research (6.3%) decreased; for legislation (12.9%), AI (14.3%) and blockchains in healthcare (16.8%) increased. Conclusions The pandemic and its aftermath present a change in academic interest. Traditional ethical fundaments in DH slightly lose position in favor of top notch technologies and apt legislation. Key messages • The pandemic and modern technologies enforced new digital health applications. Further research will reveal the needs of AI and blockchain applications respecting privacy and the ethical principles. • Besides existing legislation and regulations, in order to catch up with the dynamic developments in DH, the legal base needs to become more flexible. Technologies change, privacy importance does not.