Channel Blockage Research Articles

Particle spacing and stability of initially staggered deformable particle trains migrating in a channel

Abstract We investigated the inertial migration of deformable particles in a two-dimensional channel flow. This study analyzes the effects of the channel Reynolds number ($Re$), channel blockage ratio ($k$), particle number ($N_p$) and reduced bending modulus ($E_b$) on the formation of staggered particle trains. The results show that the stable normalized distance $d_{p_{eq}} / H$ between two staggered particles is influenced by $Re$, $k$ and $E_b$, where $H$ is the channel width. As $k$ increases or $E_b$ decreases, $d_{p_{eq}} / H$ decreases. The value of $d_{p_{eq}} / H$ initially increases and then decreases with the increase of $Re$; when $E_b$ is large and $k$ is small, $d_{p_{eq}} / H$ continuously increases with increasing $Re$. With the increase of $N_p$, the closely arranged staggered particle trains evolve into five distinct migration Regimes. We explain the conditions for the formation of each Regime and explore the mechanisms of their interconversion. The findings of this study contribute to a better understanding of the self-organization process of deformable particles in channel flow.

Analysis of hypothetical channel flow blockage of a tubular fuel assembly in a 10 MWth nuclear research reactor

Abstract Heat removal from the core of nuclear reactors is a crucial safety requirement that needs much analysis and attention. Coolant channel flow blockage is one of the unintentional cases that may influence the required heat removal rate. As a result, unsustainable over heating of the fuel cladding could occur resulting eventually in affecting the fuel integrity. This paper deals with simulating the effect of total channel flow blockage in a single fuel assembly on its steady state thermal hydraulic parameters. Thermal hydraulic calculations are carried out for the much less studied IRT-4M ducted fuel assembly type in a 10 MWth WWR-S tank in pool research reactor. The simulated IRT-4M fuel assembly comprises six rounded rectangular fuel elements in which seven channels are used for cooling. A mathematical model is developed in which all steady state thermal hydraulic parameters and their distributions could be predicted for the blocked and unblocked flow channel cases. Calculations were performed for two separate hypothetical flow channel blockage cases in the innermost channel and the middle channel of the IRT-4M fuel assembly. The results showed that the maximum clad temperatures for the two-flow blockage cases are nearly 127.4 °C, and 132.2 °C, respectively. The temperature increases resulting from a single channel blockage are not high enough to cause fuel damage, although some local coolant boiling might occur. Model validation and results support the model outcomes and its applications in the safety of the research reactor during abnormal operation.

Extended release of ciprofloxacin from commercial silicone-hydrogel and conventional hydrogel contact lenses containing vitamin E diffusion barriers.

Vitamin E could be used as a coating with commercial silicone hydrogel lenses to extend the release of various ophthalmic drugs. This concept could provide a promising approach to improve overall ocular therapeutic outcomes for topical ocular drugs. This study aimed to develop a contact lens-based ocular drug delivery system using vitamin E as a diffusion barrier to extend the release duration of ciprofloxacin. Five commercial lenses were soaked for 24 hours in various concentrations of vitamin E dissolved in ethanol (0.0125 to 0.2 g/mL). The lenses were loaded with ciprofloxacin for 24 hours in 3 mL of 3 mg/mL of ciprofloxacin/acetic acid solution. The drug release was evaluated in 3 mL of phosphate-buffered saline solution. At t = 0.5, 1, 2, 4, 6, 8, 12, 16, and 24 hours, the amount of ciprofloxacin released was measured using a UV-VIS spectrophotometer at 270 nm. There was a decrease in ciprofloxacin loading with increasing amounts of vitamin E loaded into the silicone hydrogel lenses. For each lens type, there was an optimal amount of vitamin E loaded that extended the release duration of the drug from 1 hour (without vitamin E) to as long as 16 hours. In contrast, vitamin E loaded into hydrogel lenses had no effect on the amounts of drugs loaded or the release duration. Vitamin E can be used as a diffusion barrier with commercially available silicone hydrogel lenses to provide sustained release of ciprofloxacin. The results suggest that vitamin E may form blockages in channels within a silicone hydrogel lens material, thereby forcing a longer path for drugs to diffuse into and out of the lens material. There is an optimal amount of vitamin E that needs to be loaded to extend the release duration, and this is lens material dependent.

Research on the Blocking Mechanism of Stagnant Water and the Prediction of Scaling Trend in Fractured Reservoirs in Keshen Gas Field

In this paper, well Keshen 221 was taken as the research object. The stagnant water–rock static experiment showed that, after 8 weeks of the residual water–rock static reaction, the pore size of the inner profile of the rock slice increased from 5 μm to 90 μm, and calcium carbonate crystals were deposited in the hole. Combined with the microscopic visualization model, it is observed that the reservoir blockage mostly occurs at the pore throat diameter, and the small fracture (30 μm) is blocked first, then the large fracture (50 μm). So, it is inferred that the blockage of the reservoir flow channel is caused by the migration of the crystals precipitated by the interaction between the stagnant water and the reservoir rock. On this basis, the TOUGHREACT reservoir model was further constructed to simulate the scaling of the stagnant water in the reservoir matrix and used to compare the scaling of the fractures with 7% and 30% porosity and the retained water at 0.658 m and 768 m. The pre-results of reservoir scaling show that the scaling is more serious when the fractures occur in the far well zone than when the fractures occur in the well entry zone. At the same location, the deposition of large fractures is six times that of small fractures, and the scaling is more severe in large fractures.

Research on AUV Multi-Node Networking Communication Based on Underwater Electric Field CSMA/CA Channel

To address the issues of high attenuation, weak reception signal, and channel blockage in the current electric field communication of underwater robots, research on autonomous underwater vehicle (AUV) multi-node networking communication based on underwater electric field Carrier Sense Multiple Access with Collision Avoidance (CSMA/CA) channel was conducted. This article, first through simulation, finds that the Optimized Link State Routing (OLSR) protocol has a smaller routing packet delay time and higher reliability compared to the Ad Hoc On-Demand Distance Vector (AODV) protocol on underwater electric field CSMA/CA channels. Then, a 2FSK underwater electric field communication system was established, and dynamic communication experiments were carried out between two AUV nodes. The experimental results showed that within a range of 0 to 3.5 m, this system can achieve underwater dynamic electric field communication with a bit error rate of 0 to 0.628%. Finally, to avoid channel blockage during underwater AUV multi-node communication, this article proposes a dynamic backoff method for AUV multi-node communication based on CSMA/CA. This system can achieve dynamic multi-node communication of underwater electric fields with an error rate ranging from 0 to 0.96%. The research results have engineering application prospects for underwater cluster operations.

Wood jam characteristics influence but do not fully explain wood jam morphologic functions

In-stream wood jams alter their surrounding channel morphology, thus setting riverscape morphology and ecosystem function. While wood jams clearly scour pools, retain sediment, and influence bank erosion, there is a lack of observational evidence of how wood jam characteristics themselves control morphologic effects. Here, I analyzed field observations of hundreds of wood jams to test the hypothesis that wood jam characteristics can predict local morphologic effects such as sediment retention, bar forcing, and pool scour. I found mixed support for this hypothesis: While jam characteristics such as porosity, channel blockage ratio, thalweg occupation, and having rootwads and multiple trunks significantly predicted morphologic effect occurrence and magnitude, they only explained a small portion of the variance in those morphologic effects. While wood jam characteristics are relevant in controlling their overall morphologic functions, those functions are both inherently variable and likely affected by numerous other factors, such as reach-scale topography, the sediment transport capacity to supply ratio, and interactions with surrounding wood and vegetation. Wood function restoration may be more effective if it targets reach-scale objectives across dynamic wood jam assemblages, instead of individual jams.

Cardiac dysfunction associated with lacosamide in a premature infant with Hypoxic Ischemic Encephalopathy: A case report.

Lacosamide [Vimpat® Harris FRC Corporation. © 2022 UCB, Inc. Smyrna, GA 30080] is an antiseizure medication which acts through blockage of voltage-gated neuronal sodium channels. Its recent implementation in the neonatal population has been extrapolated from adult and pediatric data suggesting a favorable safety profile. (1) Of note, preterm infants have unique developmental characteristics that may predispose them to increased risk of adverse reactions. We present a case of a preterm neonate who developed left ventricular (LV) dysfunction coinciding with the initiation of lacosamide.

Numerical Simulation of Secondary Hydrate Formation Characteristics and Effectiveness of Prevention Methods

The exploitation of natural gas hydrates by the pressure reduction method is affected by the decomposition heat absorption effect, and the range of the formation temperature reduction area is expanding. At the same time, the temperature reduction phenomenon is more significant around the production wells under the influence of gas throttling and expansion effects, and hydrate formation will occur under certain temperature and pressure conditions, leading to blockage of effective seepage channels in the reservoir in the region and elevation of seepage resistance, which may affect the output of hydrate decomposition gas. A numerical simulation model is constructed for the purpose of studying the secondary hydrate generation pattern around the well, analyzing the impact of secondary hydrates around wells on the production capacity, and assessing the effectiveness of prevention methods to inform the actual production of hydrates. The results demonstrate that secondary hydrate is typically formed in the near-well area of the upper part of the production well, and the secondary hydrate around the upper part of the production well is the first to be formed, exhibiting the highest saturation peak and the latest decomposition. The formation of the secondary hydrate can be predicted based on the observed change in temperature and pressure, and the rate of secondary hydrate formation is markedly rapid, whereas the decomposition rate, approximately 0.285 mole/d, is relatively slow. Additionally, the impact of secondary hydrates on cumulative gas production is insignificant, and the effect of secondary hydrates on capacity can be ignored. Hot water injection, wellbore heating, and reservoir reconstruction can effectively eliminate secondary hydrates around the well. Reservoir reconstruction represents a superior approach to the elimination of secondary hydrates, which can effectively enhance production capacity while preventing the generation of secondary hydrates.

Research on the Characteristics of Seepage Failure in the Surrounding Rock (Coal) of the Goafs

During mining, the brittle fracture structure of coal makes it highly susceptible to disturbance, leading to changes in the permeability of the coal seam from non-conductive to water-conductive, which poses a significant threat to the stability and safety of coal pillars in goafs. Therefore, understanding the damage mechanisms of coal during water–rock interactions is crucial for ensuring mine safety. In this paper, based on laboratory seepage tests, the impact of hydrodynamic forces on the microstructure of fissured coal and its subsequent effect on permeability is examined. The study found that increasing confining pressure causes the “closure” of coal fissures, leading to a reduction in permeability. Additionally, during the initial stage of seepage, fine particles within the coal samples are mobilized due to seepage damage, leading to channel blockages and further reductions in permeability. However, as seepage continues, the hydraulic channels eventually open fully, resulting in a sharp increase in permeability. Furthermore, using a two-dimensional fracture seepage model, the study investigated how the scale of fractures in the water-conducting channels influences seepage behavior. A critical fracture width method was proposed to predict permeability surges, offering a new approach for analyzing the stability of coal pillars in mining areas.

Flow features induced by a rod-shaped microswimmer and its swimming efficiency: A two-dimensional numerical study

Abstract The swimming performance of rod-shaped microswimmers in a channel was numerically investigated using the two-dimensional lattice Boltzmann method (LBM). We considered variable-length squirmer rods, assembled from circular squirmer models with self-propulsion mechanisms, and analyzed the effects of the Reynolds number (Re), aspect ratio (ε), squirmer-type factor (β) and blockage ratio (κ) on swimming efficiency (η) and power expenditure (P). The results show no significant difference in power expenditure between pushers (microswimmers propelled from the tail) and pullers (microswimmers propelled from the head) at the low Reynolds numbers adopted in this study. However, the swimming efficiency of pushers surpasses that of pullers. Moreover, as the degree of channel blockage increases (i.e., κ increases), the squirmer rod consumes more energy while swimming, and its swimming efficiency also increases, which is clearly reflected when ε ≤ 3. Notably, squirmer rods with a larger aspect ratio ε and a β value approaching 0 can achieve high swimming efficiency with lower power expenditure. The advantages of self-propelled microswimmers are manifested when ε > 4 and β = ±1, where the squirmer rod consumes less energy than a passive rod driven by an external field. These findings underscore the potential for designing more efficient microswimmers by carefully considering the interactions between the microswimmer geometry, propulsion mechanism and fluid dynamic environment.

Study on the Influence of Different Slot Sizes on the Flow Field of Transonic Compressor Rotors

Blade slotting technology is an effective measure to improve the flow structure on the suction surface of a blade and enhance the performance of turbomachinery. To investigate the impact of various slot sizes on the flow field of a single-stage transonic compressor rotor, seven kinds of slot schemes were designed and calculated by numerical simulations. The results show that the above slotting schemes significantly enhance the stability margin of the compressor. In particular, the slotting scheme H9W3 increases the surge margin by 60.9% and slightly reduces peak efficiency by 0.3%, with an almost identical maximum pressure ratio. Slotting promotes high-energy fluid to generate jets from the slot located at the exit of the suction side, effectively controlling blade surface flow separation and reducing channel blockage. Square slots are more effective than elongated slots for controlling separation when using differently shaped slots with equal areas. Increasing slot area gradually decreases outlet total pressure at a constant aspect ratio. A slight increase in the overall blade load causes a backward shift in the front portion load.

Mixing Enhancement Mechanism of Liquid Jet in Supersonic Crossflow with Gas Throttling

Numerical and experimental studies were conducted to uncover the physical aspects of a liquid jet injected into a supersonic crossflow with gas throttling systematically. The results were obtained with the inflow conditions of a Mach number of 2.0, a total temperature of 300 K, and a total pressure of 0.55 MPa. The results show that fuel–air mixing is considerably enhanced due to shock-induced flow distortion by adding gas throttling. The strength of downstream backpressure determines the distance of forward movement of the throttling shock wave train and the flowfield structure in the channel. When the mass flux of gas throttling is high, the influence of throttling gas spreads across the expansion section, resulting in significant flow separation in front of the liquid jet. It is found that the spray flashback phenomenon is similar to the flame flashback phenomenon that occurs in the supersonic combustion process under the action of a precombustion shock train. The wall counterrotating vortex pair and induced cavity streamwise vortices are enhanced with the increase of the flux of gas throttling. The relatively high-pressure environment generated by gas throttling promotes the atomization of droplets. As a result, the mixing enhancement mechanism of a liquid jet in a supersonic crossflow with gas throttling is mainly due to the combined effects of 1) the shock waves separating the side wall boundary layer and modifying the local flow state of air in the combustor, which lead to a dramatic increase in fuel–air mixing, and 2) the streamwise vorticity values as well as the residence time resulting from channel blockage elevating.

Influence mechanism of initial mechanical damage on concrete permeability and tunnel lining leakage

The stress state is not effectively considered in existing studies when researching the permeability evolution of concrete with initial mechanical damages, causing ambiguity in the influence mechanism of initial mechanical damage on tunnel lining leakage. This deficiency can lead to significant uncertainty in predicting the probability and evaluating the consequences of tunnel leakage diseases, further affecting the formulation of relevant prevention strategies. Therefore, mechanical damage is induced to concrete specimens by subjecting them to certain stress levels, and triaxial compression seepage tests are subsequently conducted to study the influence of initial mechanical damage on permeability evolution and macrocracks. Furthermore, the relationship between microcrack characteristics and concrete permeability is studied, ultimately revealing the influence mechanism of initial mechanical damage on tunnel lining leakage. Research results indicate that the concrete permeability decreases first, becomes stable, and then continuously increases during testing, and is positively related to changes in horizontal deformation ratio. When the damage-inducing stress reaches 80% of the uniaxial compressive strength (UCS), the impact of initial mechanical damage on concrete permeability increases significantly. The increase in initial mechanical damage can lead to a significant rise in permeability, even when the crack volume is in a compacted state. Additionally, cracks on the surface of the specimen become clearly visible when the test terminates, once the damage-inducing stress reaches 85% UCS. Two factors contribute to the gradual increase in concrete permeability with the rise in initial damage-inducing stress. Firstly, microcracks inside the concrete gradually widen and propagate. Secondly, the microcracks resulting from the initial damage progressively enlarge due to water pressure during the triaxial compression seepage test. Influenced by the blockage of seepage channels, concrete permeability can occasionally decrease during testing. The accidental load induces the gradual propagation of microcracks inside the mechanically damaged concrete. Then, the rebound deformation of concrete after the removal of the accidental load causes the closed microcracks to reopen significantly, leading to an increase in permeability and subsequent tunnel lining water leakage.

Investigation on the Water Depth of Choked Flow due to Bottom Blockages in Circular Open Channels

Investigation on the Water Depth of Choked Flow due to Bottom Blockages in Circular Open Channels

Effect of ash-bridge deposition in asymmetric diesel particulate filter channels on the pressure drop and particulate matter trapping characteristics

A diesel particulate filter (DPF) is commonly used to trap particulate matter (PM). The collapse and sintering of carbon and ash deposits during exhaust gas flow and DPF regeneration frequently result in the formation of ash bridges, which are buildups of ash and PM that clog the filter channels. To investigate the impact of an ash bridge formed by accumulated ash on the pressure drop and PM trapping characteristics of asymmetric DPFs, an asymmetric DPF channel with an ash bridge was constructed. The analysis employed computational fluid dynamics to examine how the ash bridge affects the pressure drop and PM trapping characteristics in an asymmetric DPF. This study reveals that the asymmetric DPF design effectively enhances the ash-holding capacity, thereby mitigating the risk of channel blockage. The presence of ash bridges in DPF channels has a more substantial impact on the pressure drop through radial congestion than through axial congestion. The application of asymmetric thin-wall DPFs can counteract the increase in exhaust backpressure caused by ash bridges. An ash bridge located in the middle of a DPF channel intensifies the uneven deposition of PM. However, implementing an asymmetric DPF structure enhances the uniformity of PM deposition.

Neuronal Membrane-Derived Nanodiscs for Broad-Spectrum Neurotoxin Detoxification.

Neurotoxins pose significant challenges in defense and healthcare due to their disruptive effects on nervous tissues. Their extreme potency and enormous structural diversity have hindered the development of effective antidotes. Motivated by the properties of cell membrane-derived nanodiscs, such as their ultrasmall size, disc shape, and inherent cell membrane functions, here, we develop neuronal membrane-derived nanodiscs (denoted "Neuron-NDs") as a countermeasure nanomedicine for broad-spectrum neurotoxin detoxification. We fabricate Neuron-NDs using the plasma membrane of human SH-SY5Y neurons and demonstrate their effectiveness in detoxifying tetrodotoxin (TTX) and botulinum toxin (BoNT), two model toxins with distinct mechanisms of action. Cell-based assays confirm the ability of Neuron-NDs to inhibit TTX-induced ion channel blockage and BoNT-mediated inhibition of synaptic vesicle recycling. In mouse models of TTX and BoNT intoxication, treatment with Neuron-NDs effectively improves survival rates in both therapeutic and preventative settings. Importantly, high-dose administration of Neuron-NDs shows no observable acute toxicity in mice, indicating its safety profile. Overall, our study highlights the facile fabrication of Neuron-NDs and their broad-spectrum detoxification capabilities, offering promising solutions for neurotoxin-related challenges in biodefense and therapeutic applications.

Experimental investigation of the Eckert-Weise effect (aerodynamic cooling) of pair side-by-side circular cylinders in a compressible cross-flow

The rear surface of a thermally insulated circular cylinder placed in a subsonic high-velocity cross-flow is significantly cooled, this phenomenon is known as aerodynamic cooling or the Eckert–Weise effect. This effect is associated with the redistribution of the stagnation temperature (energy separation) in the unsteady vortex wake. Experiments show that the effect is maximal at Mach numbers of the free-stream flow of 0.5–0.7, resulting in negative values of the temperature recovery factor (the temperature of the cylinder rear surface becomes lower than the static temperature of the free-stream flow). In this case, the cooling of the rear surface can reach tens of degrees. This effect can be utilized as the basis for a novel energy separation device, as it enables heat transfer between flows with the same stagnation temperatures. As shown in a numerical study (Aleksyuk, 2021), the effect is highly sensitive to the flow interference behind side-by-side cylinders, this is especially important for its practical application. In this study, the aerodynamic cooling of a pair identical circular cylinders in side-by-side arrangement, is experimentally investigated within the Mach and Reynolds number ranges of M = 0.34–0.58 and ReD = 1.6∙105–3.1∙105. The cylinder spacing considered in this study (P/D = 1.1; 1.5; 2.0; 3.0; and 4.0, where P is the center-to-center cylinder spacing and D is the diameter) covered the key regimes of vortex interference, that is, single, bistable, and coupled vortex streets. Also, investigations were conducted for a single circular cylinder with the same diameter within the Mach and Reynolds number ranges of M = 0.34–0.68 and ReD = 1.6∙105–3.4∙105. The channel blockage ratio was found to be 8% for a single cylinder and 16% for a pair of cylinders. Consequently, this study focuses on confined flow or flow past a confined cylinder with a uniform profile of oncoming flow velocity. It is shown that the Eckert-Weise effect for the pair of cylinders can either increase or decrease depending on the interference regimes and is sensitive to the blockage ratio value.

Evaluation of the effect of hydrogen evolution reaction on the performance of all-vanadium redox flow batteries

The exceptional advantages of vanadium redox flow batteries (VRFBs) have garnered significant attention, establishing them as the preferred choice for large-scale and long-term energy storage solutions. However, side reactions such as hydrogen evolution reaction (HER) lead to suboptimal performance of VRFB parameters, resulting in an overall decrease in VRFB performance. Therefore, it is imperative to investigate the mechanism by which HER affects VRFB performance and identify effective methods to mitigate its impact. In light of this, critical parameters such as charge-discharge curve, internal resistance, pressure-drop, pump power consumption, efficiency, and capacity retention rate are selected to evaluate the impact of HER on VRFB performance. Experimental results demonstrate that HER causes an increases in voltage during charging and a decrease during discharging stages leading to voltage loss; additionally, bubble generation significantly increases pressure drop and pump power consumption; furthermore, blockage of flow channels and electrodes due to bubbles leads to an increase in ohmic resistance. Finally, HER has a substantial impact on efficiency and capacity with an average energy efficiency of 2.92 %. After 60 cycles, the capacity retention rate decreased by nearly 7.69 %.

A Scalable and Robust Water Management Strategy for PEMFCs: Operando Electrothermal Mapping and Neutron Imaging Study.

Effective water management is crucial for the optimal operation of low-temperature polymer electrolyte membrane fuel cells (PEMFCs). Excessive liquid water production can cause flooding in the gas diffusion electrodes and flow channels, limiting mass transfer and reducing PEMFC performance. To tackle this issue, a nature-inspired chemical engineering (NICE) approach has been adopted that takes cues from the integument structure of desert-dwelling lizards for passive water transport. By incorporating engraved, capillary microchannels into conventional flow fields, PEMFC performance improves significantly, including a 15% increase in maximum power density for a 25 cm2 cell and 13% for a 100 cm2 cell. Electro-thermal maps of the lizard-inspired flow field demonstrate a more uniform spatial distribution of current density and temperature than the conventional design. Neutron radiography provides evidence that capillary microchannels in the lizard-inspired flow field facilitate the efficient transport and removal of generated liquid water, thereby preventing blockages in the reactant channels. These findings present a universally applicable and highly efficient water management strategy for PEMFCs, with the potential for widespread practical implementation for other electrochemical devices.

Low-temperature sintering of SiC ceramics using a mixture of preceramic precursor and metal nanoparticles

Polymer infiltration and pyrolysis (PIP) has a limitation in increasing the relative density of SiC ceramics above 90 %. This is due to the blockage of open pore channels. In this study, a new process that incorporates Ni and graphite nanoparticles into SiC preceramic precursor is examined. Ni nanoparticles react with the SiC precursor to form low melting point nickel silicide phases which infiltrate into pores of the bulk without a blockage problem. In later infiltration cycles, graphite nanoparticles are added to convert the nickel silicide to nickel carbide and silicon carbide, which may prevent the deterioration of mechanical strength at high temperature. The relative density of SiC ceramics in this study increases to 92 % and above, which is higher than that of SiC ceramics prepared by the traditional PIP. The results of this study show a pathway to process high density SiC ceramics at relatively low sintering temperatures.