On the demands of real-time and effective transmission of a huge number of data in the construction of digital blasting vibration measurement information management system, lifting wavelet algorithm was introduced for blasting vibration signal compression. Interpolation wavelet, lifting db and traditional db wavelets were used for decomposition-threshold processing-reconstruction. Compression algorithm for the short-term and non-stationary blasting vibration signal was proposed, by analyzing the compression quality. Research results lay a favorable data processing basis for the construction of digital blasting vibration measurement platform and large network blasting vibration monitoring system.