The study has depicted the analysed interpretation of importance of biomedical signal processing in medical aspects. Secondary data collection method and thematic data analysis process have been used in this study on the basis of peer reviewed journals that make the study more reliable for the readers. Basic concept of biomedical signal processing has been discussed over here with the diagnosis capability and extraction signal information of biomedical signal processing system to detect the physiological disorders. Challenges and opportunities of biomedical signal processing have been focused in this study to evaluate the impact of it in medical ground. Various applications of biomedical signals have been highlighted in this study including ECG, EEG, fEEG and many more devices. Advance technological implication in biomedical signal processing has been considered in this study highlighting the mechanical composition of ECG machine. Some recommendations of modification of biomedical signal processing system has been considered in this study such as increasing of controlling capability of diverse noise signals that can reduce power line interference. Keyword : Biomedical Signal Processing, ECG Machine, Physiological Disorders.