Excessive levels of hypochlorite (ClO-) negatively affect environmental and biological systems. Thus, it is essential to develop sensors that can identify ClO- in various systems such as the environment and living organisms. In this study, we report ... Read More
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A colorimetric/ratiometric chemosensor based on an aggregation-induced emission strategy for tracing hypochlorite in vitro and in vivo
- Ecotoxicology and Environmental Safety
- VOL. 257
on Jun 1, 2023
- Biological Systems
- Environmental Systems
- Ratiometric Fluorescent Chemosensor
- Fluorescence Color Change
- 1H NMR Titration
- Real Water Samples
- More +
Joint representation: Modeling a phenomenon with multiple biological systems
- Studies in History and Philosophy of Science
- VOL. 99
on Jun 1, 2023
- Biological Systems
- Multiple Model Systems
- Multiple Biological Systems
- Diverse Mechanisms
- Multiple Systems
- Joint Representation
- More +
Biologists often study particular biological systems as models of a phenomenon of interest even if they already know that the phenomenon is produced by diverse mechanisms and hence none of those systems alone can sufficiently represent it. To underst... Read More
Tim4, a macrophage receptor for apoptotic cells, binds polystyrene microplastics via aromatic-aromatic interactions
- Science of The Total Environment
- VOL. 875
on Jun 1, 2023
- Biological Systems
- PS Microparticles
- Cell Immunoglobulin Mucin
- PS
- PS Microplastics
- Aromatic-aromatic Interactions
- More +
Understanding the interface between microplastics and biological systems will provide new insights into the impacts of microplastics on living organisms. When microplastics enter the body, they are engulfed preferentially by phagocytes such as macrop... Read More
Mining reactive triplet carbonyls in biological systems
- Journal of Photochemistry and Photobiology B: Biology
- VOL. 243
on Jun 1, 2023
- Biological Systems
- Triplet Carbonyls
- Enhancement Of Light Emission
- Photoproduct Analysis
- Short-lived Radicals
- Resonance Energy Transfer
- More +
Aliphatic triplet carbonyls can be treated as short-lived radicals, since both species share similar reactions such as hydrogen atom abstraction, cyclization, addition, and isomerization. Importantly, enzyme-generated triplet carbonyls excite triplet... Read More
The effect of an internet-based intervention for depression on cortisol and alpha-amylase
- Psychoneuroendocrinology
- VOL. 152
on Jun 1, 2023
- Hair Cortisol Concentrations
- Change In Depression Severity
- Biological Stress Systems
- Interventions For Major Depressive Disorder
- Salivary Cortisol
- MDD
- More +
Psychotherapeutic interventions for major depressive disorder (MDD) have been suggested to be associated with a normalization of biological stress system (i.e., the hypothalamic-pituitary-adrenal axis and the autonomic nervous system) dysregulation. ... Read More
Biomimetic liposomes hybrid with erythrocyte membrane modulate dendritic cells to ameliorate systemic lupus erythematosus
- Materials Today Bio
- VOL. 20
on Jun 1, 2023
- Biological Systems
- DCs
- SLE
- Damaged Erythrocytes
- Hybrid Vesicles
- MPA
- More +
Dendritic cells (DCs)-based immunotherapy has shown immense promise in systemic lupus erythematosus (SLE) treatment. However, existing carrier strategies such as polymers, liposomes, and polypeptides, are difficult to achieve active targeting to DCs ... Read More
Genetically encoded fluorescent sensors for metals in biology
- Current Opinion in Chemical Biology
- VOL. 74
on Jun 1, 2023
- Biological Systems
- Fluorescent Sensors For Metal Ions
- Metal Ions In Biological Systems
- Understanding Mechanisms Of Toxicity
- Single Fluorescent Protein
- Metal Ions
- More +
Metal ions intersect a wide range of biological processes. Some metal ions are essential and hence absolutely required for the growth and health of an organism, others are toxic and there is great interest in understanding mechanisms of toxicity. Gen... Read More
Tritium: Its relevance, sources and impacts on non-human biota
- Science of The Total Environment
- VOL. 876
on Jun 1, 2023
- Biological Systems
- NHB
- Different Levels Of Biological Organisation
- Organismal Level Responses
- AOPs
- Levels Of Biological Organisation
- More +
Tritium (3H) is a radioactive isotope of hydrogen that is abundantly released from nuclear industries. It is extremely mobile in the environment and in all biological systems, representing an increasing concern for the health of both humans and non-h... Read More
Designing a turn-on ultrasensitive fluorescent probe based on ICT-FRET for detection and bioimaging of Hypochlorous acid
- Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy
- VOL. 294
on Jun 1, 2023
- Biological Systems
- FRET
- TD-DFT
- ICT
- Hypochlorous Acid
- Detection Of Hypochlorous Acid
- More +
Hypochlorous acid (HClO) plays an essential role in biological systems. The characteristics of potent oxidization and short lifetime make it challenging to detect specifically from other reactive oxygen species (ROS) at cellular levels. Therefore, it... Read More
A viscosity-sensitivity probe for cross-platform multimodal imaging from mitochondria to animal
- Talanta
- VOL. 258
on Jun 1, 2023
- High Viscosity Environment
- Abnormal Viscosity
- Multifunctional Imaging
- Imaging In Animals
- Change In Mitochondria
- Enhancements Of Absorption
- More +
Viscosity in biological systems is a critical factor for various physiological process, including signal transduction and metabolisms of substance and energy. Abnormal viscosity has been proven as a key feature of many diseases, thereby real-time mon... Read More
Heavy metals and metalloid in aquatic invertebrates: A review of single/mixed forms, combination with other pollutants, and environmental factors
- Marine Pollution Bulletin
- VOL. 191
on Jun 1, 2023
- Higher Organisms
- HMs
- Aquatic Invertebrates
- Factors In Biological Systems
- HM Mixtures
- Environmental Factors
- More +
Heavy metals (HMs) and metalloid occur naturally and are found throughout the Earth's crust but they are discharged into aquatic environments at high concentrations by human activities, increasing heavy metal pollution. HMs can bioaccumulate in highe... Read More
The interaction mechanism of plasma iron transport protein transferrin with nanoparticles
- International Journal of Biological Macromolecules
- VOL. 240
on Jun 1, 2023
- Formation Of Protein Corona
- Delivery Systems For Cancer Therapy
- Development Of Bioconjugates
- Formation Of Corona
- NP Physicochemical Properties
- NPs
- More +
In the biological systems, exposure to nanoparticles (NPs) can cause complicated interactions with proteins, the formation of protein corona and structural changes to proteins. These changes depend not only on NP physicochemical properties, but also ... Read More
BioSentinel: Long-Term Saccharomyces cerevisiae Preservation for a Deep Space Biosensor Mission
- Astrobiology
- VOL. 23
on Jun 1, 2023
- LEO
- Deep Space
- Deep Space Radiation
- Deep Space Environment
- Yeast's Robustness
- Trehalose Solution
- More +
The biological risks of the deep space environment must be elucidated to enable a new era of human exploration and scientific discovery beyond low earth orbit (LEO). There is a paucity of deep space biological missions that will inform us of the dele... Read More
Development of europium(III) complex functionalized silica nanoprobe for luminescence detection of tetracycline
- Methods
- VOL. 214
on Jun 1, 2023
- Detection Of TC In Milk
- Surface Of Silica Nanoparticles
- TC In Milk
- TC
- Pork Mince
- Real World Samples
- More +
Increasing awareness of the health and environment impacts of the antibiotics misuse or overuse, such as tetracycline (TC) in treatment or prevention of infections and diseases, has driven the development of robust methods for their detection in biol... Read More
Computational fluid dynamics (CFD) modeling applied to biological wastewater treatment systems: An overview of strategies for the kinetics integration
- Chemical Engineering Journal
- VOL. 466
on Jun 1, 2023
- Biological Systems
- CFD
- Biological Treatment Systems
- Computational Fluid Dynamics Modeling
- Strategies For Integration
- Fluid Dynamics Modeling
- More +
Isolation, culture, and use of primary murine myoblasts in small-molecule screens
- STAR Protocols
- VOL. 4
on Jun 1, 2023
- SMS
- Primary Myoblasts
- Transformed Cell Lines
- Culture Of Primary Myoblasts
- Primary Skeletal Myoblasts
- Culture Of Myoblasts
- More +
Small-molecule screens (SMS) are often performed using transformed cell lines that have limited physiological relevance to the biological system being investigated, resulting in poor translational outcomes. To circumvent this limitation, we present a... Read More
Current challenges and future implications of exploiting the omics data into nutrigenetics and nutrigenomics for personalized diagnosis and nutrition-based care
- Nutrition
- VOL. 110
on Jun 1, 2023
- Omics Data
- Inborn Errors Of Metabolism
- Nutrigenomics Research
- Health Care Sector
- Omics Technologies
- Regulation Of Genes
- More +
Nutrigenetics and nutrigenomics, combined with the omics technologies, are a demanding and an increasingly important field in personalizing nutrition-based care to understand an individual's response to nutrition-guided therapy. Omics is defined as t... Read More
Network pharmacology, a promising approach to reveal the pharmacology mechanism of Chinese medicine formula
- Journal of Ethnopharmacology
- VOL. 309
on Jun 1, 2023
- Network Pharmacology
- Chinese Medicine
- Chinese Herb
- Traditional Chinese Medicine
- CNKI
- Method Of Network Pharmacology
- More +
Network pharmacology is a new discipline based on systems biology theory, biological system network analysis, and multi-target drug molecule design specific signal node selection. The mechanism of action of TCM formula has the characteristics of mult... Read More
Physiological and pharmacological overview of the gonadotropin releasing hormone
- Biochemical Pharmacology
- VOL. 212
on Jun 1, 2023
- Use Of GnRH
- ART
- GnRH
- Non-peptide Agonists
- Distinct Isoforms
- Human Endometrium
- More +
Gonadotropin-Releasing Hormone (GnRH) is a decapeptide responsible for the control of the reproductive functions. It shows C- and N-terminal aminoacid modifications and two other distinct isoforms have been so far identified. The biological effects o... Read More
ПОВТОРНОЕ КРАНИОСПИНАЛЬНОЕ ОБЛУЧЕНИЕ У ПАЦИЕНТОВ ДЕТСКОГО ВОЗРАСТА С РЕЦИДИВОМ МЕДУЛЛОБЛАСТОМЫ: ОПЫТ ПРИМЕНЕНИЯ ПРОТОННОЙ ТЕРАПИИ В КЛИНИКЕ МИБС
- Pediatria. Journal named after G.N. Speransky
- VOL. 102
on Jun 1, 2023
- CSR
- MB
- Left Cerebellar Peduncle
- Single-center Retrospective Cohort Study
- Recurrent MB
- 3rd Week
- More +
Repeated craniospinal irradiation (CSR) is one of the options in the treatment of multifocal recurrences of medulloblastomas (MB), however, it is prescribed to a limited extent due to its toxicity. The use of proton therapy can reduce the toxicity of... Read More