An evolutionary transition in individuality (ETI) occurs when a previously independent organism becomes a lower level unit within a higher hierarchical level (for example, cells in an organism, ants in a colony). Using archaeological and... Read More
Biological Systems Research Articles
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Human societal development: is it an evolutionary transition in individuality?
- Philosophical Transactions of the Royal Society B: Biological Sciences
- VOL. 378
on Jan 23, 2023
- Biological Systems
- ETI
- Lower Level Unit
- Lower Level Units
- Transition In Individuality
- Higher Hierarchical Level
- More +
The Integration of Data from Different Long-Read Sequencing Platforms Enhances Proteoform Characterization in Arabidopsis
- Plants
- VOL. 12
on Jan 22, 2023
- Identification Of Proteoforms
- Proteoform Characterization
- Long-Read Sequencing
- Integration Of Data
- Protein Databases
- Sequencing Data
- More +
The increasing availability of massive omics data requires improving the quality of reference databases and their annotations. The combination of full-length isoform sequencing (Iso-Seq) with short-read transcriptomics and proteomics has been success... Read More
Impact of the Substitution Pattern at the Basic Center and Geometry of the Amine Fragment on 5-HT6 and D3R Affinity in the 1H-pyrrolo[3,2-c]quinoline Series
- Molecules
- VOL. 28
on Jan 21, 2023
- Biological Systems
- D3R Antagonist
- Basic Nitrogen Atom
- Quinoline Series
- Basic Center
- Proposed Modifications
- More +
Salt bridge (SB, double-charge-assisted hydrogen bonds) formation is one of the strongest molecular non-covalent interactions in biological systems, including ligand–receptor complexes. In the case of G-protein-coupled receptors, such an interaction ... Read More
Modularity in Nervous Systems—a Key to Efficient Adaptivity for Deep Reinforcement Learning
- Cognitive Computation
on Jan 20, 2023
- Biological Systems
- Biological Motor Control
- Biological Control Systems
- Nervous Systems
- DRL
- Good Answers
- More +
AbstractModularity as observed in biological systems has proven valuable for guiding classical motor theories towards good answers about action selection and execution. New challenges arise when we turn to learning: Trying to scale current computatio... Read More
SBML2HYB: a Python interface for SBML compatible hybrid modelling
- Bioinformatics
on Jan 20, 2023
- Biological Systems
- SBML
- SBML Format
- Hybrid Models
- Python Interface
- ML
- More +
Here we present sbml2hyb, an easy-to-use standalone Python tool that facilitates the conversion of existing mechanistic models of biological systems in Systems Biology Markup Language (SBML) into hybrid semiparametric models that combine mechanistic ... Read More
Labile Iron Pool of Isolated Escherichia coli Cytosol Likely Includes Fe-ATP and Fe-Citrate but not Fe-Glutathione or Aqueous Fe
- Journal of the American Chemical Society
on Jan 20, 2023
- Biological Systems
- Levels Of Iron Supplementation
- Aqueous Iron
- Excess Ligands
- ISCs
- Lysed Cells
- More +
The existence of labile iron pools (LFePs) in biological systems has been recognized for decades, but their chemical composition remains uncertain. Here, the LFeP in cytosol from Escherichia coli was investigated. Mössbauer spectra of whole vs lysed ... Read More
Stretchable Electrochemical Sensor Based on a Gold Nanowire and Carbon Nanotube Network for Real-Time Tracking Cell-Released H2S
- Analytical Chemistry
on Jan 20, 2023
- Biological Systems
- Stretched State
- H2S Oxidation
- Gold Nanowire
- Low Detection Limit
- Wide Linear Range
- More +
Hydrogen sulfide (H2S), as the third gas transporter in biological systems, plays a key role in the regulation of biological cells. Real-time detection of local H2S concentration in vivo is an important and challenging task. Herein, we explored a nov... Read More
Biological Calorimetry: Old Friend, New Insights
- Biophysica
- VOL. 3
on Jan 20, 2023
- Biological Systems
- Cooperative Phenomena
- Biological Insight
- Experimental Technique
- Protein Interactions
- Molecular Level
- More +
Calorimetry is an old experimental technique (first instrument developed in S. XVIII), but it is broadly used and still provides key information for understanding biological processes at the molecular level, particularly, cooperative phenomena in pro... Read More
Self-Assembly of Cyclodextrin-Coated Nanoparticles:Fabrication of Functional Nanostructures for Sensing and Delivery
- Molecules
- VOL. 28
on Jan 20, 2023
- Biological Systems
- Specific Host Guest Interaction
- Self-Assembly Of Nanoparticles
- Functional Nanomaterials
- Host Guest
- Bottom-up Approach
- More +
In recent years, the bottom-up approach has emerged as a powerful tool in the fabrication of functional nanomaterials through the self-assembly of nanoscale building blocks. The cues embedded at the molecular level provide a handle to control and dir... Read More
Bio-inspired building blocks for all-organic metamaterials from visible to near-infrared
- Nanophotonics
- VOL. 0
on Jan 20, 2023
- Biological Systems
- Subwavelength Confinement Of Light
- Natural Photosynthetic Systems
- Library Of Materials
- Light Matter Interactions
- Well-defined Nanostructures
- More +
Abstract Light-harvesting complexes in natural photosynthetic systems, such as those in purple bacteria, consist of photo-reactive chromophores embedded in densely packed “antenna” systems organized in well-defined nanostructures. In t... Read More
Neuromorphic bioelectronic medicine for nervous system interfaces: from neural computational primitives to medical applications
- Progress in Biomedical Engineering
on Jan 20, 2023
- Neural Signals
- Specific Nerve Fibers
- Neural Processing Systems
- Neuromorphic Circuits
- Microelectronic Technology
- Nervous System
- More +
Abstract Bioelectronic medicine treats chronic diseases by sensing, processing, and modulating the electronic signals produced in the nervous system of the human body, labeled 'neural signals'. While electronic circuits have been used ... Read More
The Influence of 3-D Model Biological Systems in Understanding Cellular Diversity
- International Multidisciplinary Research Journal
- VOL. 4
on Jan 20, 2023
- 3D Cell Models
- Cellular Diversity
- Tukey Multiple Comparison Test
- Instructional Models
- Academic Performance
- Product Moment Of Correlation
- More +
This study focused on the influence of instructional 3D Model Biological Systems (MBS) in understanding cell diversity. It determined the academic performance of the students according to content knowledge, quality of the artwork, and communication s... Read More
Formation mechanism of thermally controlled pH gradients
- Communications Physics
- VOL. 6
on Jan 19, 2023
- Biological Systems
- pH Gradients
- Separation Of Timescales
- Thermal Convection
- Electrostatic Forces
- Amplitude Changes
- More +
Spatial proton gradients create energy in biological systems and are likely a driving force for prebiotic systems. Due to the fast diffusion of protons, they are however difficult to create as steady state, unless driven by other non-equilibria such ... Read More
Comparison of Dissolved Organic Matter Composition and Microbial Distribution between Distributed-Inflow Biological Reactor and Two-Stage Anoxic/Aerobic for Piggery Wastewater Treatment
- Water
- VOL. 15
on Jan 19, 2023
- Piggery Wastewater
- Microbial Metabolites
- Terms Of Chemical Oxygen Demand
- DOM Components
- Large-scale Pig Farms
- Humic-like Substances
- More +
Piggery wastewater contains high amounts of feces, carbon, nitrogen, phosphorus, and other contaminants, introducing serious pollution into water, soil, and the atmosphere. Biological treatment technology is widely used in large-scale pig farms becau... Read More
Nanoceria: an innovative strategy for cancer treatment
- Cellular and Molecular Life Sciences
- VOL. 80
on Jan 19, 2023
- Biological Systems
- Challenges In Clinical Translation
- ROS
- Oxygen Tension Gradient
- Dual-catalytic Activities
- Pro-oxidative Effects
- More +
Nanoceria or cerium oxide nanoparticles characterised by the co-existing of Ce3+ and Ce4+ that allows self-regenerative, redox-responsive dual-catalytic activities, have attracted interest as an innovative approach to treating cancer. Depending on su... Read More
Two Color Imaging of Different Hypoxia Levels in Cancer Cells
- Journal of the American Chemical Society
on Jan 19, 2023
- Biological Systems
- Different Levels Of Hypoxia
- Severe Hypoxia
- Resorufin-based Probe
- Antibody-based Imaging
- Levels Of Hypoxia
- More +
Hypoxia (low oxygen levels) occurs in a range of biological contexts, including plants, bacterial biofilms, and solid tumors; it elicits responses from these biological systems that impact their survival. For example, conditions of low oxygen make tr... Read More
Role of Dietary Methyl Sulfonyl Methane in Poultry
- Animals
- VOL. 13
on Jan 19, 2023
- Biological Systems
- MSM
- Anti-inflammatory Properties
- Anti-oxidant Properties
- Oxidative Stress-induced Damage
- Chicken Diets
- More +
Oxidative stress is defined as an imbalance between pro-oxidants and anti-oxidants within biological systems, leading to tissue damage and compromising the health of afflicted animals. The incorporation of dietary anti-oxidants into chicken diets has... Read More
Flow-induced buckling of elastic microfilaments with non-uniform bending stiffness
- Frontiers in Soft Matter
- VOL. 2
on Jan 19, 2023
- Biological Systems
- Linear Stability Analysis
- Rigidity Profiles
- Stokesian Fluids
- Non-uniform Bending
- Slender-body Theory
- More +
Buckling plays a critical role in the transport and dynamics of elastic microfilaments in Stokesian fluids. However, previous work has only considered filaments with homogeneous structural properties. Filament backbone stiffness can be non-uniform in... Read More
Quantum tunneling time delay investigation of $${{\varvec{K}}}^{+}$$ ion in human telomeric G-quadruplex systems
- JBIC Journal of Biological Inorganic Chemistry
on Jan 19, 2023
- Charge Accumulation Rate
- Entropic Time
- Time Delay
- Picoampere Range
- Potential Energy Barrier
- Human Telomere
- More +
Guanine-rich quadruplex DNA (G-quadruplex) is of interest both in cell biology and nanotechnology. Its biological functions necessitate a G-quadruplex to be stabilized against escape of the monovalent metal cations. The potassium ion ([Formula: see t... Read More
Peristaltic pumping of MHD flow through a porous channel: biomedical engineering application
- Waves in Random and Complex Media
- VOL. ahead-of-print
on Jan 19, 2023
- Casson Fluid Parameter
- Porous Channel
- Biomedical Engineering Application
- Male Reproductive Tract
- Slip Boundary Conditions
- Pumping Of Flow
- More +
The study of peristaltic motion for non-Newtonian fluid has become a scorching topic of immense curiosity for analysts due to its tremendous contribution to the biological liquid transportation systems such as transportation of bile juice in a bile d... Read More