Comprehensive studies of the radiotoxicological risk at a new uranium enrichment processing facility using laser isotopic separation were motivated by the formation of industrial uranium oxide aerosols identified at UO2+Umetal and U3O8. Taking the new ICRP recommendations into account, this study was aimed at determining for each of those uranium oxides the physicochemical and biokinetics parameters which are required in order to calculate committed dose per unit of intake (DPUI). Activity median aerodynamic diameter was measured between 5.2 and 10 µm with the presence of fine particles under 1µm reaching, in some cases, up to 20%, concentration at the workstation varied from 1.8 to 125 Bq.m-3 and biological half-times were calculated from in vitro and in vivo experiments, leading to a main biological half-time of 77 days for UO2+Umetal particles and 187 days for U3O8 particles. DPUI values using these experimental results were assessed between 1.7x10-6 and 2.9 x 10-6 Sv.Bq-1 for UO2+Umetal and between 1.8x10-6 and 3.2x1-6 Sv.Bq-1 for U3O8.