In the agricultural sector, where factors like the type of agriculture, management techniques, and access to funding are critical, disadvantaged people face significant barriers to employment. This study investigated the effects of these factors, especially with regard to sustainability and social farming, on the employment of disadvantaged persons in the Czech Republic. We sent questionnaires to 2036 agricultural businesses within the Czech Republic, and the data we received were sorted and analyzed. There was a favorable relationship between farm size and employment chances. Disadvantaged people were more likely to be hired by large farms, especially those larger than 250 hectares. Furthermore, mixed-production farms were more capable of employing disadvantaged persons, unlike conventional farms, which reached their maximum employment levels at one, three, or six workers. Organic farming had a more even distribution, while biodynamic farming showed limited capacity to employ disadvantaged persons. Farms involved in fundraising had fewer farms but employed more disadvantaged persons (number of employees peaked at two, four, and six), while farms that did not engage in fundraising hired more disadvantaged individuals (peaked at one and three employees). The motivations for employing disadvantaged persons were primarily social concerns, as well as labor shortages and economic and innovative factors. These findings show the importance of agricultural enterprises using these factors to improve the social and economic well-being of disadvantaged persons.