The high moisture content of municipal solid waste yields a lower energy content of solid fuel that affects the thermal conversion efficiency. Biodrying is an alternative drying method using bio-heat generated by microbial metabolism to reduce the moisture content of municipal solid waste. This research was conducted in three pilot-scale biodrying reactors, two under greenhouse conditions compared with one conventional non-greenhouse condition. Two bunkers with greenhouse cladding were connected with aerators, and airflow rates were set at 0.4 and 0.6 m3/(kgwaste·day), respectively. Meanwhile, a passive aeration method was applied to the non-greenhouse bunker. This study aims to investigate the effect of the greenhouse condition on the biodrying process and assess the performance of the drying process through different operating conditions. The result shows that the greenhouse mainly affects the air temperature rise in the reactor. The aeration rate is positively correlated with weight reduction (r = 0.93). At 0.6 m3/(kgwaste·day) airflow rate, the treatment can reach a moisture content less than 30% on average within ten days, while at 0.4 m3/(kgwaste·day) airflow rate, it takes 15 days to reduce the moisture content to less than 30%. Biodrying under the greenhouse condition with active aeration potentially achieves desirable moisture content reduction and heating value increase more efficiently than the common biodrying. However, the airflow rate is a crucial factor in determining the suitable drying time in biodrying under the greenhouse condition.