Binary Systems Research Articles

Experimental study and correlation of critical parameters for three binary mixtures containing R290 and hydrofluoroolefins

The mixtures of R290 (propane) and R1234yf (2,3,3,3-tetrafluoroprop-1-ene), R1243zf (3,3,3-trifluoropropene), or R1234ze(E) (trans-1,3,3,3-tetrafluoropropene) could be potential alternatives for high global warming potential (GWP) refrigerants hydrofluorocarbons (HFCs) and hydrochlorofluorocarbons (HCFCs). Obtaining the critical parameters of mixtures is crucial for establishing thermodynamic models, evaluating the highest operating temperature of refrigerants, determining the phase envelope, and confirming the starting point of the Widom line. However, few studies have been made on their critical properties. In this work, the critical properties of three binary systems containing R290 + R1234yf / R1243zf / R1234ze(E) are obtained experimentally with a metal-bellows volume apparatus. The critical state is judged by direct visual observation of critical opalescence and the recurrence of the vapor-liquid phase interface. The extended total uncertainties for the mole fraction, critical pressure, critical temperature, and critical density were below 0.004, 21 kPa, 50 mK, and 0.6 % (k=2, 0.95 confidence coefficient), respectively. Experimentally obtained critical data are correlated by the Modified Wilson method and the Redlich-Kister method. The critical parameters of the R290 + R1234yf, R290 + R1243zf, and R290 + R1234ze(E) mixtures are predicted using the Correlated Modified Wilson (CMW) method, He et al.’s method, and the Modified Extended Chueh-Prausnitz (MECP) method. The correlated curve and predicted outcomes are employed for comparison with this work's experimental results. Meanwhile, the critical parameters data obtained experimentally are contrasted with the value of REFPROP 10.0 and other open literature. The fitting and prediction curves somewhat agree with the experimental results.

SHS of copper Chevrel phase compounds

Chevrel phase (CP) compounds are a highly multifunctional class of materials but are underused due to the high energy processing required for their synthesis. Self-propagation high-temperature synthesis (SHS) is a low energy and quick alternative for synthesizing this material system. In this investigation, copper-based CPs were synthesized via SHS using either elemental or binary precursor powders. The elemental precursors produced non-stoichiometric Cu2.76Mo6S8, and consisted mainly of grown MoS2 platelets. The binary precursor, on the other hand, produced stoichiometric Cu2Mo6S8. The influences of mixing and precursor concentration are discussed as well as the reaction mechanisms operating for the elemental system and the binary system, separately. The investigation into this synthesis process aims to provide a better understanding of the Chevrel SHS mechanism to accurately control the product.

BRAF-V600E mutations in plasma and peripheral blood mononuclear cells correlate with prognosis of pediatric Langerhans cell histiocytosis treated with first-line therapy.

The clinical relevance of BRAF-V600E alleles in peripheral blood mononuclear cells (PBMCs) and the prognostic impact of the mutants in cell-free (cf) and PBMC DNAs of Langerhans cell histiocytosis (LCH) have not been fully clarified in pediatric LCH. We retrospectively determined the levels of BRAF-V600E mutation in paired plasma and PBMC samples at the time of diagnosis of LCH. Subsequently, we performed a separate or combined analysis of the clinical and prognostic impact of the mutants. We assessed BRAF-V600E mutation in peripheral blood from 94 patients of childhood LCH. Our data showed that cfBRAF-V600E was related to young age, multiple-system (MS) disease, involvements of organs with high risk, increased risk of relapse, and worse progression-free survival (PFS) of patients. We also observed that the presence of BRAF-V600E in PBMCs at baseline was significantly associated with MS LCH with risk organ involvement, younger age, and disease progression or relapse. The coexisting of plasma(+)/PBMC(+) identified 36.2% of the patients with the worst outcome, and the hazard ratio was more significant than either of the two alone or neither, indicating that combined analysis of the mutation in plasma and PBMCs was more accurate to predict relapse than evaluation of either one. Concurrent assessment of BRAF-V600E mutation in plasma and PBMCs significantly impacted the prognosis of children with LCH. Further prospective studies with larger cohorts need to validate the results of this study.

Multifaceted biomedical applications of bismuth oxide-doped bioactive glass: Synthesis challenges, characterization and potential clinical implications

Herewith, the present work reports a facile synthesis method of Bi2O3 doped 70 SiO2.30CaO binary bioactive glass system termed as modified Bi-BG (acronymed as mBi-BG) that indicates successful incorporation of Bi3+ into the silicate glassy network, on prior complex formation of the precursor bismuth nitrate salt with acetyl acetone to address the rapid decomposition rate of precursor bismuth nitrate. The binary bioactive glass composition as above mentioned (70 SiO2.30CaO) is named as BG/Control. The synthesis methodology addresses inherent challenges encountered in traditional sol-gel derived bismuth oxide incorporated bioactive glass (Bi-BG) synthesis wherein yellow coloured bismuth oxide gets separated from the glassy network as confirmed by XRD phase analysis. Next, mBi-BG (modified Bi-BG) was synthesized via modifying the sol gel method by introducing a chelating agent acetyl acetone to stabilize the precursor Bi (NO3)3 salt, and was characterized using XRD, FTIR, FESEM-EDX. TG-DSC and BET isotherm. In vitro bioactivity studies illustrate the formation of hydroxyapatite crystals on mBi-BG surface indicating its potential for bone repair and regeneration. Additionally, mBi-BG exhibits significant effect against Staphylococcus aureus (gram-positive) bacterial strain, highlighting its utility in preventing bacterial infections at surgical sites. Radiographic imaging of mBi-BG reveals excellent radiopacity comparable to human bone, rendering it suitable for image-guided surgeries and fluoroscopic procedures. In summary, mBi-BG emerges as a versatile biomaterial with enhanced bioactivity, antibacterial efficacy and radiopacity, thereby offering novel avenues in medical treatment modalities and patient care.

Deciphering the transfer mechanisms for CO2 absorption into binary blended solutions

A thorough understanding of the mechanisms involved in CO2 chemical absorption is crucial for the development of efficient CO2 capture technologies. Due to the insufficient insight into the interaction mechanism of different components in blended solutions, CO2 absorption reactions were often categorized as unidirectional transfer between absorption products. In this study, the CO2 absorption performance of binary blended solutions, including piperazine (PZ)/n-methyldiethanolamine (MDEA), ethanolamine (MEA)/MDEA, ammonia (NH3)/MDEA, PZ/potassium carbonate (K2CO3), and NH3/K2CO3, was investigated using a combination of experimental and computational methods. The CO2 absorption mechanisms of "competitive reaction", "transfer reaction" and "parallel reaction" in the binary blended solution system were proposed. Kinetic experiments revealed that different blended solutions had varying impacts on the process of CO2 absorption. Among them, PZ/MDEA and MEA/MDEA solutions reduced the absorption rates by an average of 8% and 25%, respectively, compared to PZ or MEA component solutions. NH3/MDEA and PZ/K2CO3 solutions had absorption rates similar to those of single NH3/PZ component solutions. NH3/K2CO3 solutions, on the other hand, exhibited an average increase of 17% in absorption rates compared to NH3 solutions. Quantum mechanical (QM) methods were employed to evaluate of the absorption products and key processes in terms of kinetics and thermodynamics. Quantitative 13C NMR analyses were conducted to further investigate the interactions between components and the pathways of mass transport in blended solutions, which demonstrated proton transfer and CO2/-COO transfer between adsorption products. This study highlights an accurate description of the transfer mechanisms of various blended systems for the enhanced CO2 capture.

Absorption-Desorption Characteristics of the Synthesized Deep Eutectic Solvents for Carbon Dioxide Capture

The development of an environmentally friendly CO2 absorbent with significant energy utilization which can be an alternative to CO2 capture by an ethanolamine solution is presently an obligatory issue. In this work, binary and ternary deep eutectic solvents (DESs) were prepared according to their CO2 absorption/desorption performances. A series of DESs comprise different hydrogen bonding donor (HBD)- acceptor (HBA) pairs as CO2 capturing solvents; HBAs include choline chloride (ChCl) and tetrabutylammonium bromide (TBAB), and selected amines are represented as HBDs and include monoethanolamine (MEA), diethanolamine (DEA), and triethanolamine (TEA). Binary DESs synthesized of ChCl/MEA, ChCl/DEA, ChCl/TEA, TBAB/MEA, TBAB/DEA, and TBAB/TEA in a CO2 absorption cell at a mole ratio of 1:4. While selected amidines were represented as super-based (SB) and included 1,5-Diazabicyclo [4.3.0] non-5-ene (DBN) and 1,8-Diazabicyclo [5.4.0] undec-7-ene (DBU). The ternary DESs were prepared by adding DBN or DBU to the binary DESs system in a (1:4:3) molar ratio. CO2 absorption experiments were attained at atmospheric pressure and a temperature of 30 °C using 15 vol.% CO2 with 85 vol.% N2. On the other hand, the regeneration process for DESs was conducted at 90 oC. Binary DES synthesized from ChCl/MEA gives a higher absorption rate of CO2 of 0.0177 mole/kg. min, CO2 absorption loading of 2.9092 mole CO2/kg solvent, cyclic loading of 2.0001 mole CO2/kg solvent, and a regeneration efficiency of 68.75%. The synthesis DESs showed a better performance compare with a common Ionic liquids.

Hybrid nano-biocomposite based on polysaccharide and graphene oxide for the practical separation of proteins in a fixed bed adsorption column

Proteins and amino acids are essential to humans and all living beings. Moreover, these compounds are present in the pharmaceutical, food, and cosmetic industries. Proteins need to be purified for use in industry. This work aims to synthesize and apply a nano-biocomposite based on graphene oxide (GO) and agar (polysaccharide) for protein separation and purification. The hydrogel composite was tested for myoglobin (Mb) adsorption, the effect of changing the initial pH in Mb adsorption, and the ionic strength was evaluated. The adsorptive capacity values were higher at pH=5 and 6 and decreased at higher pH values. The increase in NaCl concentration did not affect the adsorptive capacity significantly. The composite exhibited a notorious value of maximum experimental adsorption capacity in the equilibrium of over 790 mg g−1 at pH=5 and 25 °C. As GO interacts with the polymeric agar matrix, resulting in a 3D material, the material developed could adsorb Mb in a fixed bed column and single and binary (BSA+Mb) systems. There are indications that the GO-based composite possibly forms a complex with the peptide ligands of myoglobin, forming a protein corona, making Mb desorption difficult.

Prediction of solubility of CO2, H2S, and their mixture in ionic liquids using the Cubic Two State equation of state

In this work, the capability of the Cubic Two State (CTS) equation of state (EoS) has been evaluated using the solubility of carbon dioxide (CO2), hydrogen sulfide (H2S), and their mixture in ionic liquids (ILs). The imidazolium-based ILs with [BF4], [PF6], and [Tf2N] anions have been studied. The self-association between IL molecules, CO2, and H2S molecules has been considered to optimize the pure model parameters. In addition to self-association between similar molecules, the cross-association between CO2-IL and H2S-IL in the binary mixtures has been considered. The results show that the CTS EoS can predict (kij=0.0) the solubility of H2S and CO2 in ILs ranging from 1 to 1000 bar satisfactory. The average ARD value for binary CO2-IL and H2S-IL systems has been obtained 20.3% and 9.02, respectively. The CTS model has been used to predict the phase behavior of ternary systems containing CO2-H2S-[C4mim][PF6], CO2-H2S-[C8mim][PF6], and CO2-H2S-[C8mim][Tf2N] at various temperatures. Finally, the CTS results have been compared to soft-SAFT and PC-SAFT EoSs. The results show that simple association contribution and the cubic term of the CTS EoS can model the molecular interactions between gases and ILs satisfactory. The CTS model can be considered as a robust and efficient thermodynamic model for the prediction of separation of CO2 and H2S using ILs.

Design and mediated hydrogen bonding strength of Poly(styrene-alt- N–(ethyl–4–hydroxyphenyl)maleimide) copolymer to enhance miscibility with hydrogen bonded acceptor homopolymers

In this study, the monomer N–(ethyl–4–hydroxyphenyl)maleimide (TyHPMI) was synthesized from tyramine and maleic anhydride. Subsequently, free radical copolymerization was used to prepare the poly(S–alt–TyHPMI) alternating copolymer by reacting TyHPMI with styrene. We confirmed the chemical structure using Fourier transform infrared (FTIR), 1H and 13C nuclear magnetic resonance (NMR). The sequence distribution of the poly(S–alt–TyHPMI) alternating copolymer was analyzed using mass–analyzed laser desorption ionization/time–of–flight (MALDI–TOF) mass spectrometry. Differential scanning calorimetry (DSC) measurements showed a single glass transition temperature (Tg) across various weight fractions of binary blended systems containing strong hydrogen–bonded acceptors, such as poly(S–alt–TyHPMI)/poly(4–vinyl pyridine) (P4VP) and poly(vinyl pyrrolidone) PVP, implying full miscibility. The Tg values predicted by kwei equation for the poly(S–alt–TyHPMI)/P4VP and poly(S–alt–TyHPMI)/PVP blends show a positive deviation from linearity. This deviation is due to the short alkyl chain reinforcing the addition of acidic TyHPMI units, which enhances intermolecular hydrogen bonding between the pyridyl or C=O groups and the OH units of the TyHPMI segment. As a result, FTIR spectral analyses indicate that the intermolecular hydrogen bonding between pyridyl and C=O groups is stronger in the poly(S–alt–TyHPMI) copolymer compared to the poly(S–alt–HPMI) copolymer. This is supported by the larger ratio of the inter/self-association equilibrium constant (KA/KB) value.

Liquid-liquid equilibrium of binary ethanol–polyisobutene and ternary ethanol–water–polyisobutene systems under low- and high-pressure conditions: An assessment using the PC-SAFT equation of state

Sugarcane bioethanol in either anhydrous or hydrous forms stands out as an economically viable bioproduct that can be used as a fuel or feedstock in various innovative applications, reducing human-generated greenhouse gas emissions. Low-molar-mass polyisobutene (PiB) is used as a lubricant in sugarcane-processing plants and is a possible contaminant of sugarcane bioethanol. Understanding the liquid–liquid equilibrium (LLE) of ethanol–PiB binary systems and ethanol–water–PiB ternary systems is essential to avoid undesired phase separation at high-pressure engine conditions and other potential innovative applications. However, the experimental investigation of these systems is significantly hampered by very low polymer solubilities in aqueous ethanol. The LLE of ethanol-PiB and ethanol–water-PiB mixtures was qualitatively investigated using the PC-SAFT equation of state through the development and implementation of extrapolation strategies allowing to estimate ethanol-PiB and water-PiB binary parameters using experimental data obtained for other systems containing lighter alkanes. Phase diagrams were calculated considering temperatures ranging from 298.15 K to 350 K and pressures ranging from 1 bar to 200 bar. It was shown that lower pressures, higher temperatures, lower PiB molar masses, and lower water contents increase the polymer solubility in the solvents. Thus, the risk of liquid–liquid separation can be mitigated by correctly managing such operational parameters. The obtained phase diagrams may present significant quantitative deviations from reality because of the model’s sensitivity to the estimated binary parameters. Thus, they should be interpreted as general qualitative guidelines to avoid and manage undesired phase separation in industrial processes and engines rather than phase equilibrium predictions.

Long-term Speckle Interferometric Monitoring of Binary Systems: 2007–2023 Positional Measurements and Orbits of Seven Objects

The results of seventeen years of speckle interferometric monitoring of seven objects (Chara 122Aa, GJ 3010, HIP 1987, GJ 3076, HIP 11253, HIP 11352, and HIP 14929) are presented. Observational data were obtained at the 6 m Big Telescope Alt-azimuthal Special Astrophysical Observatory of the Russian Academy of Science (BTA SAO RAS) from 2007 to the present. Analysis of previously published and new measurements made it possible to construct completely new orbits for Chara 122Aa, HIP 11253, and HIP 14929. The orbit of GJ 3076 cannot be constructed accurately due to the large influence of the weights assigned to the measurements. The resulting orbital solutions are classified based on a grading scheme suggested by W.I. Hartkopf, B.D. Mason and C.E. Worley; most orbits are “definitive” (Grade 1). The mass sums and masses of components calculated by two independent methods using Hipparcos and Gaia DR2 and DR3 parallaxes were compared for the objects under study.

Stability and viability of charged anisotropic pulsar SAX J1748.9-2021 in extended symmetric teleparallel gravity

This manuscript aims to study the viability and stability of a pulsar SAX J1748.9-2021, containing a charged anisotropic matter configuration within the framework of f(Q,T) theory (Q and T are the non-metricity scalar and energy–momentum tensor, respectively). We employ a non-singular solution and a specific model of this gravitational theory and use junction conditions to determine the unknown constants in the metric coefficients. We explore different geometric and physical properties using astrophysical observations from the pulsar SAX J1748.9-2021, which is found in X-ray binary systems within globular clusters. This framework establishes relationships between various physical quantities, including fluid parameters, anisotropy, mass–radius relation, redshift, the Zeldovich condition, energy conditions, causality conditions, adiabatic index, Tolman–Oppenheimer–Volkoff equation, equation of state parameter and compactness. Our findings affirm the feasibility and stability of the proposed charged pulsar within this theoretical framework.

Tidal Love numbers from EFT of black hole perturbations with timelike scalar profile

We study static tidal Love numbers (TLNs) of a static and spherically symmetric black hole for odd-parity metric perturbations.We describe black hole perturbations using the effective field theory (EFT), formulated on an arbitrary background with a timelike scalar profile in the context of scalar-tensor theories.In particular, we obtain a static solution for the generalized Regge-Wheeler equation order by order in a modified-gravity parameter and extract the TLNs uniquely by analytic continuation of the multipole index ℓ to non-integer values.For a stealth Schwarzschild black hole, the TLNs are vanishing as in the case of Schwarzschild solution in general relativity.We also study the case of Hayward black hole as an example of non-stealth background, where we find that the TLNs are non-zero (or there is a logarithmic running).This result suggests that our EFT allows for non-vanishing TLNs and can in principle leave a detectable imprint on gravitational waves from inspiralling binary systems, which opens a new window for testing gravity in the strong-field regime.

Discovery of 226 [formula omitted] Scuti and [formula omitted] Doradus Stars near NGC 6871 with TESS

We present the discovery of 269 pulsating variable stars of δ Scuti, γ Doradus, and Maia types in the vicinity of the open cluster NGC 6871, using data from the Transiting Exoplanet Survey Satellite (TESS). Our small-scale regional survey centered on the δ Scuti star V1821 Cyg in the open cluster NGC 6871, covering a radius of one degree. The results include a remarkable total of 1,512 newly classified variable stars, comprising the following categories: 105 δ Scuti stars, 121 γ Doradus stars, 50 Maia variables, 198 eclipsing binary systems, with 12 exhibiting pulsating or rotating components, 500+ rotating variable stars, and dozens of other types. Out of 1,512 newly discovered variable stars, 108 are confirmed members of NGC 6871 with a membership probability exceeding 50%. Notably, dedicated Fourier analyses were applied to eight representative stars from the newly discovered variables. Among these, one star exhibits a rich and complex pulsation spectrum characterized by amplitude variations in dominant pulsations. To contextualize the new pulsators, we plotted them in the Hertzsprung-Russell diagrams alongside the largest known group of class member stars. Surprisingly, both δ Scuti and γ Doradus stars occupy nearly the same region in the diagrams, hinting at a potential unified pulsation mechanism. This study contributes valuable insights into the variability census of NGC 6871 and sheds light on the pulsation behavior of different stellar types. Further investigations into the physical properties and evolutionary status of these stars are warranted.

Observational signature of QPOs with particle motion around non-commutative Schwarzschild black hole surrounded by perfect fluid dark matter

We analyze the orbital and oscillatory motion of test particles in the vicinity of a non-commutative black hole submerged in perfect fluid dark matter and derive analytical solutions for the specific angular momentum and radial profiles of energy. Using the effective potential approach, we discuss the stability of circular orbits. Furthermore, we calculate the innermost stable circular orbits. The effective force acting on particles has also been discussed. We find the expressions for frequencies of radial and latitudinal harmonic oscillations as a function of the black hole mass and the model’s parameters. The key features of quasi-periodic oscillations of test particles near the stable circular orbits in an equatorial plane of the black hole are discussed. Furthermore, Periastron precession has been discussed. We demonstrate that the parameters of the model have a strong influence on particle motion around black holes. By using the observational data of four different X-ray binary systems GRO J1655-40, XTE J1550-564, XTE J1859+226, and GRS 1915+105, within the scope of Monte Carlo Markov Chain, we constrain the involved parameters α and β. It is necessary to mention that our presented investigations through graphical behavior are viable with required physical behavior.

First principles study of the structure and superconductivity of La-Ge alloys under high pressure

High pressure is a fundamental approach for discovering and developing new materials, where adjusting the pressure can induce phase transitions and novel properties, such as superconductivity. In this study, we conduct a comprehensive investigation of the structural and electronic properties of La-Ge compounds within the pressure range of 0-30GPa by using first-principles calculations. Three new stable compounds have been identified, namely I4/mmm_La2Ge, Fd3̅m_LaGe2, and P6/mmm LaGe5. In combination with the known structures, the pressure-component phase diagram of the La-Ge binary system is constructed. The results of electronic structure calculations indicate that all structures represented in this diagram exhibit metallic properties. The new structure Fd3̅m_LaGe2 with C15 Laves phase is predicted to be stabilized dynamically from 23GPa up to at least 30GPa. The calculations of superconducting properties reveal that both Fd3̅m_LaGe2 and Immm_LaGe5 are superconductors with critical temperatures of 5.9K at 23GPa and 6.3K at 0GPa, respectively. Superconductivity observed in both Fd3̅m_LaGe2 and Immm_LaGe5 can be attributed primarily to the coupling between Ge-4p electrons and phonons situated in proximity to the Fermi level. Our results indicate that phases with elevated Tc are more prevalent in compounds with a higher proportion of Ge atoms in the total density of states. These findings are expected to provide theoretical guidance for future experimental investigations of La-Ge system, facilitating the exploration of C15-type superconductors in the form of AB2.

Organo magadiites for diclofenac adsorption: influence of the surfactant chain.

The presence of drugs in aquatic environments has been considered a global challenge and several remediation technologies have been proposed, including adsorption. In this study, new diclofenac adsorbents were obtained from the reaction of sodium magadiite (Na-Mag) with surfactants dodecylpyridinium chloride hydrate (C12pyCl) and hexadecylpyridinium chloride monohydrate (C16pyCl)), 1-hexadecyltrimethylammonium bromide (C16Br), and dodecyltrimethylammonium bromide (C12Br). The synthesis was carried out in the microwave at 50°C for 5min using surfactant amounts of 100% and 200% in relation to the cation exchange capacity of Na-Mag. The elemental analysis indicated that surfactants with a longer organic chain were more incorporated into Na-Mag, whose values were 1.42 and 1.32mmolg-1 for C16pyMag200% and C16Mag200%, respectively. X-ray diffraction results suggested formation of intercalated products with basal space in the range of 2.81-4.00nm. Diclofenac was quickly adsorbed on all organophilic magadiites, at an equilibrium time of 1min. Drug capacity adsorption was influenced by the arrangement and packing density of organic cations, the basal distance, and the organic contents of the samples at high drug concentrations. Alkylpyridinium magadiites exhibited maximum adsorption capacities higher than alkylammonium magadiites, of 96.4, 100.7, 131.7, and 166.1mgg-1 for C12pyMag100%, C12pyMag200%, C16pyMag100%, and C16pyMag200%, respectively, at pH 6.0 and 30°C. Diclofenac removal by samples was not affected by the presence of ibuprofen, which was also removed from binary system by organophilic magadiites reaching removal of 76.5% and 86.9% by C16pyMag100% and C16pyMag200%, respectively. Regeneration studies demonstrated a drug removal percentage of 83-92% for C16pyMag and C16Mag after three cycles of adsorption.

Efficient co-removal of aqueous Cr(VI) and ciprofloxacin by alkali lignin-derived carbon supported nanoscale zero-valent iron via adsorption and redox synergistic mechanisms

Developing an efficient co-removal strategy is crucial for the treatment of combined contaminants with heavy metals and antibiotics due to their great threat to sustainable advancement and ecological preservation. Herein, the efficient co-removal of aqueous hexavalent chromium (Cr(VI)) and ciprofloxacin (CIP) is achieved via a newly developed composite of nanoscale zero-valent iron particles embedded into alkali lignin-derived carbon (nZVI/ALC) without external assistance (such as light, advanced oxidants). nZVl/ALC demonstrates superior co-removal efficiencies of Cr(VI) (99.9 %) and CIP (89.9 %) with high removal kinetic rate constants of 1.595 and 0.779 min−1, respectively. The underlying mechanisms involving the co-removal of Cr(VI) and CIP verify that Cr(VI) ions are adsorbed onto the skeleton of nZVI/ALC originating from the electrostatic interaction, and CIP molecules adsorbed on nZVl/ALC act as a bridge, complexing with the Cr(VI) ions to promote Cr(VI) removal. Meanwhile, the CIP adsorption by nZVI/ALC involves hydrogen bonding, π-π interaction, and complexation. The coexisting Cr(VI) ions are transformed into Cr(III) components with abundant electron transfer, leading to the generation of more •O2– radicals, thus the self-generating reactive oxygen species (•OH, •O2– and 1O2) in ambient-air condition promote CIP degradation in the binary system. The CIP molecules’ degradation pathways mainly include piperazine ring cracking, piperazine epoxidation, quinolone ring opening and defluorination according to the analysis of HPLC-MS and FuKui function, along with the gradual reduction in toxicity throughout the degradation process of CIP molecules. This study offers a new insight on the co-removal of Cr(VI) and CIP, which would provide promising guidance for the remediation of compound wastewater with heavy metals and antibiotics.

Myocardial Ischemic Syndromes: A New Nomenclature to Harmonize Evolving International Clinical Practice Guidelines.

Since the 1960s, cardiologists have adopted several binary classification systems for acute myocardial infarction (MI) that facilitated improved patient management. Conversely, for chronic stable manifestations of myocardial ischemia, various classifications have emerged over time, often with conflicting terminology-eg, "stable coronary artery disease" (CAD), "stable ischemic heart disease," and "chronic coronary syndromes" (CCS). While the 2019 European guidelines introduced CCS to impart symmetry with "acute coronary syndromes" (ACS), the 2023 American guidelines endorsed the alternative term "chronic coronary disease." An unintended consequence of these competing classifications is perpetuation of the restrictive terms "coronary" and 'disease', often connoting only a singular obstructive CAD mechanism. It is now important to advance a more broadly inclusive terminology for both obstructive and non-obstructive causes of angina and myocardial ischemia that fosters conceptual clarity and unifies dyssynchronous nomenclatures across guidelines. We, therefore, propose a new binary classification of "acute myocardial ischemic syndromes" and "non-acute myocardial ischemic syndromes," which comprises both obstructive epicardial and non-obstructive pathogenetic mechanisms, including microvascular dysfunction, vasospastic disorders, and non-coronary causes. We herein retain accepted categories of ACS, ST-segment elevation MI, and non-ST segment elevation MI, as important subsets for which revascularization is of proven clinical benefit, as well as new terms like ischemia and MI with non-obstructive coronary arteries. Overall, such a more encompassing nomenclature better aligns, unifies, and harmonizes different pathophysiologic causes of myocardial ischemia and should result in more refined diagnostic and therapeutic approaches targeted to the multiple pathobiological precipitants of angina pectoris, ischemia, and infarction.

Myocardial ischaemic syndromes: a new nomenclature to harmonize evolving international clinical practice guidelines.

Since the 1960s, cardiologists have adopted several binary classification systems for acute myocardial infarction (MI) that facilitated improved patient management. Conversely, for chronic stable manifestations of myocardial ischaemia, various classifications have emerged over time, often with conflicting terminology-e.g. 'stable coronary artery disease' (CAD), 'stable ischaemic heart disease', and 'chronic coronary syndromes' (CCS). While the 2019 European guidelines introduced CCS to impart symmetry with 'acute coronary syndromes' (ACS), the 2023 American guidelines endorsed the alternative term 'chronic coronary disease'. An unintended consequence of these competing classifications is perpetuation of the restrictive terms 'coronary' and 'disease', often connoting only a singular obstructive CAD mechanism. It is now important to advance a more broadly inclusive terminology for both obstructive and non-obstructive causes of angina and myocardial ischaemia that fosters conceptual clarity and unifies dyssynchronous nomenclatures across guidelines. We, therefore, propose a new binary classification of 'acute myocardial ischaemic syndromes' and 'non-acute myocardial ischaemic syndromes', which comprises both obstructive epicardial and non-obstructive pathogenetic mechanisms, including microvascular dysfunction, vasospastic disorders, and non-coronary causes. We herein retain accepted categories of ACS, ST-segment elevation MI, and non-ST-segment elevation MI, as important subsets for which revascularization is of proven clinical benefit, as well as new terms like ischaemia and MI with non-obstructive coronary arteries. Overall, such a more encompassing nomenclature better aligns, unifies, and harmonizes different pathophysiologic causes of myocardial ischaemia and should result in more refined diagnostic and therapeutic approaches targeted to the multiple pathobiological precipitants of angina pectoris, ischaemia and infarction.