Nowadays, heating cables are used as heat sources for heating pavements in practical engineering. However, there is a contradiction between the snow melting function and the interlaminar stability of heating pavement. In order to solve the contradiction, the interlaminar failure behavior of asphalt mixture coupled heating cables specimen (AMCS) was researched, through experiments and the finite element method. Under the different conditions of heating cables and rolling times, a series of direct shear tests was performed at the interface of AMCS, to compare the interlaminar stability of three different AMCS. Meanwhile, based on the bilinear cohesive zone model and coulomb friction model a 2D finite element model was established, to simulate this shear failure processes and make up for the limitations of the experiment. According to above test and simulation results, the failure mechanism and the weakest interface in AMCS were found, and the influence of the heating cable’s diameter and embedded spacing on the interlaminar shear strength were found. Then, a modified coulomb theorem model was proposed to predict the shear strength of the AMCS. This research enriches the design theory of the heating pavement and it has great significance for its structural design of heating asphalt pavement.