Bilateral Serous Macular Detachment Research Articles

Bilateral retinal detachment – when the kidney meets the eye

Exudative retinal detachment occurs when fluid accumulates between the neurosensory retina and the retinal pigment epithelium. Ocular diseases or multisystem conditions such as nephrotic syndrome may lead to exudative retinal detachment. This report describes a case of nephrotic syndrome secondary to minimal change disease, anasarca and bilateral serous macular detachment in an adult patient. A 75-year-old male patient presented to the emergency department with generalized edema, asthenia, and visual impairment. Medical history included a recent diagnosis of nephrotic syndrome [...]

Bilateral Serous Macular Detachment as a Complication of Preeclampsia: A Case Report

Bilateral Serous Macular Detachment as a Complication of Preeclampsia: A Case Report

Bilateral Serous Macular Detachment as a Complication of Preeclampsia: A Case Report

Bilateral Serous Macular Detachment as a Complication of Preeclampsia: A Case Report

Bilateral Serous Macular Detachment After Attempted Suicide with Pregabalin.

A 24-year-old female presented with bilateral vision loss following attempted suicide with pregabalin. Her best-corrected visual acuity (BCVA) was 20/40 in the right eye and 20/50 in the left eye. The bilateral visual disturbance was associated with serous macular detachment. Fundus examination of both eyes showed foveal serous retinal detachment, which was confirmed by optical coherence tomography. Topical nepafenac 0.1% eye drops were started as single drop every 8 hours for 4 weeks. One month later, the serous macular detachment had regressed and BCVA increased to 20/20 in both eyes. To the best of our knowledge, this is the first reported case of bilateral serous macular detachment presumably caused by pregabalin intoxication.

Dexamethasone intravitreal implant for treatment of persistent macular oedema in Birdshot retinochoroidopathy

Clinical caseThe case is reported of a 32 year-old man with a bilateral cystoid macular oedema and serous macular detachment due to Birdshot retinochoroidopathy. An intravitreal implant of 0.7mg dexamethasone (Ozurdex®, Allergan) was performed on both eyes, after a partial response of the macular oedema to oral and subtenon corticosteroids. Anatomical and visual improvements were observed and maintained after six months of follow up. DiscussionIntravitreal dexamethasone implant may be a good therapeutic option in patients with macular oedema due to Birdshot retinochoroidopathy, and who were refractory or had intolerance to previous therapies.

Implante intravítreo de dexametasona como terapéutica del edema macular persistente en la retinocoroidopatía de Birdshot

Clinical caseThe case is reported of a 32 year-old man with a bilateral cystoid macular oedema and serous macular detachment due to birdshot retinochoroidopathy. An intravitreal implant of 0.7mg dexamethasone (Ozurdex®, Allergan) was performed on both eyes, after a partial response of the macular oedema to oral and subtenon corticosteroids. Anatomical and visual improvements were observed and maintained after six months of follow up. DiscussionIntravitreal dexamethasone implant may be a good therapeutic option in patients with macular oedema due to Birdshot retinochoroidopathy, and who were refractory or had intolerance to previous therapies.

Electrooculogram (EOG) findings in a case of acute exudative polymorphous vitelliform maculopathy (AEPVM) detected following trauma

The purpose of this study was to monitor a case of acute exudative polymorphous vitelliform maculopathy detected following trauma. Clinical examination included fundus photographs, optical coherence tomography (OCT) and fluorescein angiography. Pattern and full-field electroretinograms (PERG; ERG) and serial electrooculograms (EOG) were performed, incorporating the international standards. A 45-year-old Caucasian woman developed blurring of vision in both eyes 5 days after a serious road traffic accident. On examination, bilateral serous macular detachments and multiple small yellow subretinal lesions were observed in both eyes associated with areas of serous retinal detachment superior and inferior to the yellow lesions in the left eye. OCT showed retinal elevation with a band of high reflectance on the outer retina but no intra-retinal fluid or elevation of the retinal pigment epithelium (RPE). There was bilateral EOG reduction in keeping with generalised RPE dysfunction and pattern ERG evidence of left macular involvement. After 9 months, the patient reported spontaneous improvement in vision with gravitational settling and coalescence of the subretinal yellow deposits. At 37 months, there was improvement in the EOG and visual acuity. A rare case of AEPVM is described that was detected following trauma and which gradually improved over 37 months. The EOG showed evidence of generalised RPE dysfunction that resolved and may be useful in the monitoring of AEPVM.

The causes of serous macular detachment excluding central serous chorioretinopathy

The causes of serous macular detachment excluding central serous chorioretinopathy Burak Turgut, Fatih Cem Gul, Tamer Demir, Ulku CelikerDepartment of Ophthalmology, Fırat University School of Medicine, Elazıg, TurkeyObjective: In our study, we investigate the causes of serous macular detachment (SMD) excluding central serous chorioretinopathy (CSC).Study design/patients and methods: A retrospective observational study. The medical records of 58 patients with SMD documented by optical coherence tomography (OCT) were reviewed retrospectively. The patients with CSC were excluded from the study. Ocular diseases accompanied with SMD, unilaterality or bilaterality, and demographical properties of the patients were evaluated.Results: Of the 58 patients with SMD in this study, 20 (34.4%) were women and 38 (65.5%) were men. The ages of patients were between 17 to 81 years (median 61.01 years). The causes of SMD were as follow: diabetic macular edema (DME) in 37 patients (63.8%), age-related macular degeneration (AMD) associated with choroidal neovascularization in 10 patients (17.24%), branch retinal vein occlusion in five patients (8.62%), central retinal vein occlusion in four patients (6.90%), Harada disease in one patient (1.72%) and Coat’s disease in one patient (1.72%). Eighteen patients with DME, two patients had AMD associated with choroidal neovascularization, and one patient with Harada disease had bilateral SMD. The most common cause of SMD in both eyes was DME.Conclusions: The most common cause of SMD excluding CSC seems to be DME. The presence of SMD in retinal vascular diseases such as diabetes might affect the results of the treatment and the prognosis.Keywords: serous macular detachment, causes, diabetic macular edema, age-related macular degeneration, excluding central serous chorioretinopathy

Vogt-Koyanagi-Harada Syndrome Associated With Bilateral Serous Macular Detachments Responsive to Immunomodulatory Therapy

<h4>EXCERPT </h4> <p>A 44-year-old woman presented to our institution with bilateral red and painful eyes and an associated decrease in vision. There was no significant ocular or medical history. However, she had received the influenza vaccination 1 month previously. There was no history of trauma, and the presence of tinnitus was noted on review of the systems.</p> <h4> </h4>

Intravitreal injection of triamcinolone acetonide for serous macular detachment in a patient with systemic lupus erythematosus.

To report our experience with intravitreal triamcinolone acetonide treatment of serous macular detachment in a patient with active systemic lupus erythematosus (SLE). Interventional case report. A 38-year-old man who had SLE with bilateral serous macular detachment and retinopathy was treated with a single intravitreal injection of triamcinolone acetonide in one eye and two intravenous injections of a megadose steroid. Serous detachment in the eye injected with intravitreal steroid showed more significant improvement than that in the fellow eye. Our case suggests that intravitreal triamcinolone acetonide injection may be considered for treatment of SLE-related serous macular detachment that does not respond to systemic steroid therapy.

Bilateral serous macular detachment in a woman on sildenafil for pulmonary hypertension.

To report a case of bilateral serous macular detachment in a woman on sildenafil for pulmonary hypertension. Case report of a 52-year-old woman presenting with painless loss of vision bilaterally after starting sildenafil 1 month earlier for pulmonary hypertension. Bilateral serous macular detachment with cystoid macular edema was noted on funduscopy and optical coherence tomography (OCT). Fluorescein angiography showed several pinpoint areas of faint leakage with pooling in late views. Vision subjectively normalized 1 week after discontinuing sildenafil. Funduscopy and OCT also normalized on follow-up examination. Bilateral serous macular detachment can be associated with sildenafil use for pulmonary hypertension. Vision loss is reversible with prompt discontinuation of the drug.

Acute Lymphoblastic Leukemia Presenting as Bilateral Serous Macular Detachments

Acute Lymphoblastic Leukemia Presenting as Bilateral Serous Macular Detachments

Acute Lymphoblastic Leukemia Presenting as Bilateral Serous Macular Detachments

Acute Lymphoblastic Leukemia Presenting as Bilateral Serous Macular Detachments

Optical coherence tomography study of tilted optic disk associated with macular detachment

To describe the macular findings by optical coherence tomography in both eyes of a patient with tilted optic disk and visual decrease. A 35-year-old woman with bilateral tilted optic disk and serous macular detachment was examined by slit-lamp biomicroscopy, fluorescein angiography, indocyanine green angiography and optical coherence tomography (OCT). Fluorescein angiography demonstrated staining of the temporal rim of the staphyloma adjacent to the optic disk and hyperfluorescence of the diffuse pigmentary changes in the papillomacular area. Leakage points and serous macular detachment were not observed. The existing neurosensory detachment at the fovea became evident only by OCT. The existence of subretinal fluid, which became evident only by OCT, supports the view that OCT could further contribute to the study of the asymptomatic pigmentary lesions of the macula that are present in 11% of eyes with tilted optic disk. The reason for the localized macular detachment remains unclear. Dysfunction of the retinal pigment epithelium (RPE) or leakage of the optic disk staphyloma rim could possibly explain the cause of fluid accumulation in the macula.

Bilateral Serous Macular Detachment as a Presenting Feature of Acute Lymphoblastic Leukemia

To report a case of bilateral serous maculopathy as an initial sign of acute lymphoblastic leukaemia in children. A 13-year-old girl, who presented with symptoms of visual blurring, was found to have a bilateral serous maculopathy. Haematological abnormalities (thrombocytopenia with a mild lymphocytosis) prompted further investigation. A bone marrow aspirate revealed the presence of leukemic blasts and a diagnosis of acute lymphoblastic leukaemia was made. Her maculopathy completely resolved following systemic chemotherapy. Prompt recognition of disease led to early systemic treatment and restoration of visual function.

Bilateral serous macular detachment following laser in situ keratomileusis

To report a case of bilateral serous macular detachment following laser in situ keratomileusis (LASIK). Observational case report. A 33-year-old man presented with sudden decrease of vision in both eyes 4 days following uncomplicated LASIK in both eyes for spherical equivalent of +5.00 diopters sph in the right eye and +7.00 diopters sph in the left eye. Detailed history with ocular and systemic examination, fluorescein angiography, and optical coherence tomography were done. Retinal examination had a documentation of retinal pigment epithelium atrophy in the macular region in both eyes pre-LASIK. A diagnosis of central serous chorioretinopathy (CSCR) was made in both eyes, with multifocal alterations in the retinal pigment epithelium and a pocket of serous retinal fluid in the macular region confirmed on OCT. Late venous phase of fluorescein angiogram demonstrated multiple hyperfluorescent foci of leakage, more in the right eye with areas of retinal pigment epithelium staining. Preexisting macular pathology, such as retinal pigment epithelium atrophy could be a new contraindication to LASIK for hypermetropia with possible development of CSCR, requiring a careful examination of the fundus pre-LASIK.