Big Deal Research Articles

Corona XXI – outside the frame

Corona XXI – outside the frame

Hybrid Electric Charging Station using Raspberry Pi

Our world is running out of fossil fuel so people start to change themselves and started to use an electric vehicle. In electric vehicles the charging is a big deal, this project includes solar and wind energy charging mechanism to generate power for electric vehicle both day and night. And it contains Raspberry pi that is programmed to calculate the amount of power charged for an electric vehicle, then the user can know that the information via Blynk application. The power generated by solar panel setup is given to the battery via DC-DC converter because the power from solar panel setup is a variable DC, so that is converted into pure DC. And the power generated by wind generator setup is given to battery via AC – DC converter, the power from a wind generator is AC, so that is converted into DC.

A theory of information overload applied to perfectly efficient financial markets

PurposeIn the era of big data investors deal every day with a huge flow of information. Given a model populated by economic agents with limited computational capacity, the paper shows how “too much” information could cause financial markets to depart from the assumption of informational efficiency. The purpose of the paper is to show that as information increases, at some point the efficient market hypothesis ceases to be true. In general, the hypothesis cannot be maintained if the use of the maximum amount of information is not optimal for investors.Design/methodology/approachThe authors use a model of cognitive heterogeneity to show the inadequacy of the notion of market efficiency in the modern society of big data.FindingsTheorem 1 proves that as information grows, agents' processing capacities do not, so at some point there will be an amount of information that no one can fully use. The introduction of computer-based processing techniques can restore efficiency, however, also machines are bounded. This means that as the amount of information increases, even in the presence of non-human techniques, at some point it will no longer be possible to process further information.Practical implicationsThis paper explains why investors very often prefer heuristics to complex strategies.Originality/valueThis is, to the authors’ knowledge, the first model that uses information overload to prove informational inefficiency. This paper links big data to informational efficiency, whereas Theorem 1 proves that the old notion of efficiency is not well-founded because it relies on unlimited processing capacities of economic agents.

Sequence Risk: Is It Really a Big Deal?

Financial planners are keenly aware of, and routinely warn clients about, sequence risk; that is, the possibility of facing a sequence of low returns early in retirement that may force retirees to scale down the plans they had made. This really is a scary scenario, but one that the evidence here shows that retirees are not very likely to encounter. A new and refined definition of sequence risk is advanced in this article, linking this type of risk to the sustainability of a withdrawal strategy. Furthermore, three ways of assessing sequence risk are proposed, among them one that enables a retiree to monitor the sustainability of his withdrawal strategy periodically and to introduce adjustments when necessary. The ultimate message of this article is that retirees should be informed, but not obsess, about sequence risk.

Wellness in the Time of COVID: Helping Your Residents Stay Active and Achieve Their Potential

Wellness in the Time of COVID: Helping Your Residents Stay Active and Achieve Their Potential

Anticoagulants and Progression of Injury after Subdural Hematoma: Doomsday Clock or No Big Deal?

Sadri, Lili MD; Martin, Jennifer PhD; Katsnelson, Jacob MD; Traczuk, Ashley; Leigh Butler, Karyn MD, FACS Author Information

ADC field boosted by 2 big deals

It’s been a big week for the field of . In the largest deal in its 33-year history, Gilead Sciences has agreed to pay $21 billion to acquire Immunomedics and its recently approved antibody-drug con...

\u201c\u2018You lose your hair, what\u2019s the big deal?\u2019 I was so embarrassed, I was so self-conscious, I was so depressed:\u201d a qualitative interview study to understand the psychosocial burden of alopecia areata

BackgroundAlopecia areata (AA) is characterized by hair loss that can affect the scalp and body. This study describes the psychosocial burden of AA.MethodsParticipants diagnosed with AA who had experienced ≥50% scalp hair loss according to the Severity of Alopecia Tool (SALT) were identified by clinicians. A semi-structured interview guide, developed with expert clinician input, included open-ended questions to explore patients’ experiences of living with AA. Data were thematically analyzed to identify concepts and relationships.ResultsParticipants (n = 45, 58% female, mean age 33.3 years [range 15–72], mean SALT 67.2 [range 0–100]) described the AA diagnosis as “devastating”. Both males and females reported emotional and psychological impacts of AA including feeling sad/depressed (n = 21), embarrassed/ashamed (n = 10) and angry/frustrated (n = 3). Patients felt helpless (n = 5) due to the unpredictability of disease recurrence, and anxious (n = 19) about judgement from others. Many patients avoided social situations (n = 18), which impaired relationships and increased isolation. Coping strategies included concealment of hair loss through wigs or make-up, although fear of the displacement of these coverings also caused anxiety and the avoidance of activities that could result in scalp exposure (n = 22). Some patients became more accepting of AA over time, which lessened the emotional impact, though efficacious treatment was still desired. A conceptual framework was developed, and a conceptual model was created to depict the relationship between the physical signs/symptoms and the associated psychosocial effects of AA.ConclusionAA impairs patients’ emotional and psychological wellbeing, relationships and lifestyles. Greater disease awareness and effective treatments are needed.

President's Page

Growing up, 90 was always a big deal — going 90 miles an hour, hitting 90°F outside, getting 90/100 on a test. And now, we celebrate the 90th year of SEG's founding. Happy birthday, SEG! From those days in 1930, when 30 individuals first formed a geophysical association of fellow explorers, entrepreneurs, and scientists, to our Society today with some 12,000 members in 120 countries, it's been almost a century of progress. Traveling back 90 years, we would find a world population of some 2 billion (versus almost 8 billion today), U.S. life expectancy of 60 years (now pushing 80), and oil production of less than 4 million barrels per day compared to current levels of about 90 million. Interestingly, then as now, there was an oil glut and volatile stock market. However, on 18 April 1930 in contrast to our plethora of current events, the BBC announced that, “there is no news today” and played piano music! Oh, for those days … aside from the bit about a 60-year life expectancy.

Roundtable Discussion: The Challenge of Developing Effective Sterilization and Reprocessing Instructions for Use.

Roundtable Discussion: The Challenge of Developing Effective Sterilization and Reprocessing Instructions for Use.

Black cargo

Black cargo

Variables Analysis of Tourism Apps Development in Influencing Tourist Travel Experience

Dumping of apps that emphasized on how to develop tourism industry and help travel organization to promoting their business. However, every app has own advantages and disadvantages. Producing an apps need a properly research about needs and demands of tourist or traveller itself. The tourism apps have its own influence towards tourists when it’s come to their satisfaction of travelling. Producing of tourism apps can be expansion if the producer increases the requirements, by doing a research of tourist’s needs and demand. Every tourist has their own needs and demands that are influenced by their preference, identity and family background. These factors are developed from many criteria, such as their culture which influence their identity, and their power of buying which influences their taste and preferences. Tourism industry is a wide field, before certain products are produced and certain services are offered, the producers need to analyse their target market. Thus, the success of a tourism App depends on how well and deep the producer has managed to explore and study about the target users. Research that linked between product and user needs on tourism apps are a big deal to explore. Successful of apps depends on how producer of tourism apps study about the users. The finding of paper is variables analysis of tourism apps that can be used to developing new prototype of tourism apps based on tourist needs. This paper will introduce the best variables that have been analysing to be interesting features that can be including in tourism apps.

Surgical face masks as a potential source for microplastic pollution in the COVID-19 scenario

Although there have been enormous reports on the microplastic pollution from different plastic products, impacts, controlling mechanisms in recent years, the surgical face masks, made up of polymeric materials, as a source of microplastic pollution potential in the ecosystem are not fully understood and considered yet. Current studies are mostly stated out that microplastics pollution should be a big deal because of their enormous effect on the aquatic biota, and the entire environment. Due to the complicated conditions of the aquatic bodies, microplastics could have multiple effects, and reports so far are still lacking. In addition to real microplastic pollutions which has been known before, face mask as a potential microplastic source could be also researching out, including the management system, in detail. It is noted that face masks are easily ingested by higher organisms, such as fishes, and microorganisms in the aquatic life which will affect the food chain and finally chronic health problems to humans. As a result, microplastic from the face mask should be a focus worldwide.

Prenominal adjective order is such a fat big deal because adjectives are ordered by likely need.

When multiple adjectives precede a noun in English, they are often ordered in a way that is implicitly understood by all fluent speakers of the language. Adjective order might be described as a big fat deal, but to describe it as a fat big deal betrays a lack of knowledge of English. Sweet (A New English Grammar: Part II, 1898/1955) proposed two related semantic principles to explain the phenomenon: definiteness of denotation (adjectives that denote a property that is most independent of the modified noun must be placed furthest fromthat noun) and closeness of adjective/noun in meaning (adjectives that denote properties essential to or inherent in the modified noun are placed closer to the noun). These observational descriptions of the phenomenon have received experimental support (Martin, Journal of Verbal Learning and Verbal Behavior, 8(6), 697-704, 1969). However, the issue of why Sweet's rules are true has not yet been solved. I propose, operationalize, test, and find strong support for a simple theory: that prenominal adjective order reflects likely need, the a priori probability that a particular adjective will be needed.

Capital mobility in commodity-exporting economies

Abstract This paper studies capital mobility in commodity-exporting economies. These countries substantially depend on world commodity prices and have rather high level of savings on average, so it is naturally to assume that they demonstrate special patterns of capital mobility. Our main hypothesis is that constraints on capital mobility in this group of countries depend upon the level of savings compared to the level of investments. In particular, with high savings that follow higher world demand and higher commodity prices, financing country’s desirable level of investment is not a big deal. At the same time, in the case of negative terms of trade shocks these commodity-exporting economies may experience lower savings and higher country risk-premium. This may lead to restrictions on borrowing capital in the global market, resulting in a high correlation between investments and savings. The results of threshold regressions speak in favour of our hypothesis.

What is the experience of our patients with transient hypoparathyroidism after total thyroidectomy?

BackgroundWe sought to better understand the experience of patients with transient hypoparathyroidism using patient interviews and quality of life surveys. MethodsThis is a prospective analysis of 62 patients after total thyroidectomy at a high-volume institution. Semistructured patient interviews and quality of life surveys were conducted preoperatively and postoperatively at 2 weeks, 6 weeks, 6 months, and 1 year and compared based on postoperative parathyroid hormone levels. ResultsPostoperative parathyroid hormone levels were <10 pg/mL in 32% of patients (n = 20), 10 to 20 pg/mL in 19% (n = 12), and >20 pg/mL in 48% (n = 30). Hypocalcemic symptoms at 2 weeks were reported in 28 of 55 patients (51%), but patients felt “well prepared” and reported it “wasn’t a big deal.” If symptoms persisted at 6 weeks, they became more bothersome. At 6 months and 1 year, patients reported calcium supplementation prevented most symptoms and did not interfere with daily activities. Quality of life as measured by the European Organization for Research and Treatment of Cancer and the 12-Item Short Form Survey demonstrated a slight improvement at 1 year postoperatively regardless of parathyroid hormone level. ConclusionEarly postoperative transient hypoparathyroidism is common but when appropriately managed did not have a substantial negative impact on the overall quality of life.

Negotiating big deals: ACRL/SPARC Forum at the 2020 ALA Midwinter Meeting

At the ACRL/SPARC Forum at the 2020 ALA Midwinter Meeting in Philadelphia, three panelists discussed efforts to negotiate with vendors regarding “Big Deal” journal packages, including strategies and information that make such negotiations more effective for libraries. The three panelists provide their remarks below. Gale Etschmaier recounts negotiations between the Florida State University Libraries and Elsevier that led to the successful cancellation of their Elsevier “Big Deal.” Robin Sinn summarizes open access efforts at the Johns Hopkins University Libraries. And, finally, Jason Priem discusses his company’s product Unsub, a “data dashboard that helps libraries forecast, explore, and optimize their alternatives to the Big Deal, so they can unsubscribe with confidence.”

Current and Future molecular mechanism in Inflammation and Arthritis.

Inflammation is an immune response of the human body but excessive inflammation is taken as a major factor in the development of many diseases including autoimmune disorders, cancer and nerve disorders etc. In this regards the need is to suppress the inflammatory response. Suppression of extra or imperfect inflammatory response is not a big deal provided there is an exact knowledge of particular target in the body. Recent advancements in Pharmacological aspect made the therapy with improved outcomes in number of patients. Anticytokine therapy might be one of the important and novel approaches for inflammation and Arthritis. This can be achieved only when we go through the pathophysiology of expression and identification of mediators. Let’s take an example of cytokine like interleukins (IL), chemokines, interferons (INF), tumor necrosis factors (TNF-α), growth factors, and colony stimulating factors) release pathway which is a major signalling protein in inflammatory response. In the present study we have reviewed the recent pharmacological therapeutic advancement, inflammatory mediators, receptors, and major signalling pathways. Such information will not only provide the idea about the mechanism of action of Pharmaceuticals and molecular targets but also it provides a new aspect for drug designing and new corrective approaches in existing clinical medicines. This study will be a source of good information for the researchers working in the area of drug designing and molecular Pharmacology especially in anti-inflammatory and anti arthritic medicines for target based therapy.

Secondary School Teachers’ Perception on Stem Integrated Education: A Analysis

American President Barak Obama said on Third Annual White House Science Fair in April 2013 that “One of the things that I’ve been focused on as President is how we create an all-hands-on-deck approach to science, technology, engineering, and math… We need to make this a priority to train an army of new teachers in these subject areas and to make sure that all of us as a country are lifting up these subjects for the respect that they deserve”. This single part of the speech pinpoint the importance of STEM education and backbone of it “Teachers”. Cross disciplinary appeals have manifold appeals. Same is in the field of school education. Once it’s a time, science has a leading role at elementary and secondary school level. Then engineering becomes the prominent figure but when technology comes, all other fields merged in it. Mathematics remains the mother of all subjects. Now, it’s a time of STEM integrated education where STEM is the acronym of Science, Technology, Engineering and Mathematics. STEM is not only confined to an acronym but also leads to the change of education system or approach from the root level. Presented study aimed at to highlight the secondary school teachers’ perception regarding STEM education. As it’s a new and novel concept, so not a big deal of work has done on it. So, existing literature was analyzed systematically to highlight the importance, challenges and future of STEM education which surely helpful to introduce in the developing countries like Pakistan. Presented study just focused on the perception and viewpoints of teachers who are working at elementary or secondary school level. Study concluded that teachers are highly motivated and confident for the STEM integrated education but there is a dire need to give suitable policy for this new trend of education which ultimately addresses the issues of curriculum, pedagogy, learning environment, career developers and future of the learners

Is Labor Market Mismatch a Big Deal in Japan?

Abstract This paper estimates Japanese labor market mismatch between 2000 and 2019 by using the method of Sahin et al. (“Mismatch Unemployment.” The American Economic Review 104 (11): 3529–64, 2014). We quantify contract-type (regular or non-regular), employment-type (full or part-time), and occupational mismatch and their respective contributions to changes in unemployment. All three types of mismatch show a countercyclical pattern, sharply increasing during the global financial crisis (GFC), but slowly declining during the recovery. Contract-type and occupational mismatch accounted for a significant portion of the rise in the unemployment rate during the GFC, each accounting for around 30 and 20–40 percent, respectively. Employment-type mismatch, on the other hand, accounted for much less–at around 15 perecent of the rise in unemployment for the same period.