Biaxial Tests Research Articles

Asymmetric Sample Shapes Complicate Planar Biaxial Testing Assumptions by Intensifying Shear Strains and Stresses

Planar biaxial testing offers a physiologically relevant approach for mechanically characterizing thin deformable soft tissues, but often relies on erroneous assumptions of uniform strain fields and negligible shear strains and forces. In addition to the complex mechanical behavior exhibited by soft tissues, constraints on sample size, geometry, and aspect ratio often restrict sample shape and symmetry. Using simple PDMS gels, we explored the unknown and unquantified effects of sample shape asymmetry on planar biaxial testing results, including shear strain magnitudes, shear forces measured at the sample’s boundary, and the homogeneity of strains experienced at the center of each sample. We used a combination of finite element modeling and experimental validation to examine PDMS gels of varying levels of asymmetry, allowing us to identify effects of sample shape without confounding factors introduced by the nonlinear, spatially variable, and anisotropic properties of soft tissues. Both biaxial simulations and experiments, which showed strong agreement, revealed that sample shape asymmetry led to significantly larger shear strains, shear forces, and overestimation of principal stresses. Excluding these shear forces resulted in an underestimation of shear moduli during inverse mechanical characterizations. Even in the simplest of deformable biomaterials, sample shape asymmetry should be avoided as it can induce drastic increases in shear strains and shear forces, invalidating traditional planar biaxial testing analyses. Alternatively, sample shape asymmetry may be exploited to generate more robust estimates of constitutive parameters in more complex materials, which could lead to a refined understanding and inference of mechanical behavior.

A rationalized macroscopic failure criterion of composite woven fabrics for airship structures

Composite woven fabrics are increasingly employed in architecture and aerospace for their excellent properties, such as lightweight, high specific strength, large surface area, and satisfactory deployability. The strength behavior is essential for various membrane structures as structural failure is serious. However, an accurate, simplified, and universal failure criterion has not been reported due to the inherent complexities of composite woven fabrics. This paper thus studies the tensile strength behaviors of airship fabrics and proposes a rationalized macroscopic failure criterion (Chen-Chen criterion) based on theoretical analysis and experimental observations. The generalized Chen-Chen criterion inherently satisfies the conditions of symmetry, dimensionless, and uniaxial tensile strength (UTS) boundary, with a maximum absolute deviation of only 1.34 % for two airship fabrics. Additionally, the UTS-based criteria were derived particularly for flexible plain-weave polyesters to avoid laborious and costly biaxial strength tests. The average deviations of constant and linear Chen-Chen criteria are 6.01 %, 4.91 %, while that of the Norris criterion reaches 13.34 %. Furthermore, the numerical implementation of the Chen-Chen criterion was demonstrated by biaxial tensile simulations. The failure strength and location predicted by the numerical analysis show good consistency with the experimental results.

Effect of the Intaglio Surface Treatment and Thickness of Different Types of Yttria-Stabilized Tetragonal Zirconia Polycrystalline Materials on the Flexural Strength: In-Vitro Study

Background: Surface treatment of the intaglio surface of zirconia is important for bonding. However, it could affect the strength of the materials. The purpose of this study is to compare the effect of laser, etching, and air abrasion surface treatment methods to a control group on the flexural strength of three zirconia materials with two different thicknesses. (1) Methods: A total of 120 disks were divided into three groups according to the type of zirconia and the ceramic thickness. Then, according to the surface treatment method, the groups were divided into four subdivisions. The change in the microstructure of the ceramic material was investigated through Scanning Electron Microscope (EVO LS10, Carl Zeiss SMT Ltd. Oberkochen, Germany). Phase identification was performed using an X-ray diffraction device (XRD; Ultimate IV X-ray Diffractometer, Rigaku Inc., Tokyo, Japan). The flexural strength was assessed with a biaxial flexural strength test in a universal testing machine. Data were analyzed using SPSS Software (SPSS version 26.0.Armonk, NY: IBM Corp). A three-way ANOVA and a post hoc Dunnett T3 test were employed to evaluate the effect of the yttria concentration, thickness, and surface treatment on the flexural strength of zirconia (α = 0.05). (2) Results: At 0.8 mm thickness, air abrasion significantly increased the flexural strength of 3Y-TZP (1130.6 ± 171.3 MPa) and 4Y-TZP (872 ± 108.6 MPa). However, air abrasion significantly decreased the flexural strength of 5Y-TZP materials (373 ± 46.8 MPa). Laser irradiation significantly decreased the flexural strength of 5Y-TZP (347 ± 50.3 MPa), while etching significantly decreased the flexural strength of both 3Y-TZP (530 ± 48.8) and 4Y-TZP (457.1 ± 57.3). When the thickness increased to 1 mm, air abrasion continued to significantly decrease the flexural strength of 5Y-TZP materials. (3) Conclusions: There was a negative effect of surface treatment on the flexural strength at 0.8 mm thickness rather than at 1 mm thickness. Air abrasion enhances the flexural strength of 3Y-TZP and 4Y-TZP materials but significantly reduces the flexural strength of 5Y-TZP materials. Zircos-E etching and Er:YAG surface treatment methods did not significantly reduce the flexural strength of 5Y-TZP materials at 1 mm thickness and can be recommended as an alternative surface treatment for 5Y-TZP materials.

Modular soft pneumatic actuator mimics elephant trunk locomotion

Robots support and facilitate tasks in all life fields. Soft robots specifically have the advantages of inherent compliance, safe interaction and flexible deformability. Soft pneumatic network (Pneu-Net) is a soft pneumatic actuator (SPA) composed of network of chambers that is actuated by pneumatic power. Soft Pneu-Net fits the human interface applications perfectly. In this paper, a bio-inspired modular based design for Pneu-Net actuator is developed. The actuator mimics the elephant trunk curling to be employed for rehabilitation of human hand fingers. The actuator is an integrated four Pneu-Net modules actuator which is attached to hand’s finger. The main introduced advantages in the new developed actuator are: providing four degrees of freedom (DoF) essential for finger’s motion by single compound actuator and developing a methodology for a modular soft Pneu-Net actuator that is efficiently reproducible. The actuator’s design is developed using computer aided design (CAD) software SOLIDWORKS. The design is simulated using finite element modeling (FEM) software ABAQUS. Fabrication process uses 3D printed molds. Soft material is molded in the 3D printed molds, forming actuator’s modules. Actuator’s modules are integrated by adhesion using the soft material. A proposed non-standard hyper-elastic material biaxial tension test is introduced as a quick material properties identification method that can produce a test table used for material identification in the FEM. Enhanced version for the actuator uses reinforcement fibers. Results show advances for the reinforced actuator, as it limits the unwanted actuator’s strain and deformation. The reinforced actuator shows improved energy efficiency reaches to 46%.

Estimation of the biaxial tensile behavior of ovine esophageal tissue using artificial neural networks

Diseases of the esophagus affect its function and often lead to replacement of long sections of the organ. Current healing methods involve the use of bioscaffolds processed from other animal models. Although the properties of these animal models are not exactly the same as those of the human esophagus, they nevertheless present a reasonable means of assessing the biomechanical properties of the esophageal tissue. Besides, sheep bear many similarities physiologically to humans and they also suffer from same diseases as humans. The morphology of their esophagus is also comparable to that of humans. Thus, in the study, an ovine esophagus was studied. Studies on the planar biaxial tests of the gross esophageal anatomy are limited. The composite nature of the gross anatomy of the esophagus makes the application of structure-based models such as Holzapfel-type models very difficult. In current studies the tissue is therefore often separated into specific layers with substantial collagen content. The effects of adipose tissue and other non-collagenous tissue often make the mechanical behavior of the esophagus widely diverse and unpredictable using deterministic structure-based models. Thus, it may be very difficult to predict its mechanical behavior. In the study, an NARX neural network was used to predict the stress–strain response of the gross anatomy of the ovine esophagus. The results show that the NARX model was able to achieve a correlation above 99.9% within a fitting error margin of 16%. Therefore, the use of artificial neural networks may provide a more accurate way of predicting the biaxial stress–strain response of the esophageal tissue, and lead to further improvements in the design and development of synthetic replacement materials for esophageal tissue.

Smeared fixed crack model for quasi-static and dynamic biaxial flexural response analysis of aluminosilicate glass plates

Glass materials are extensively used in load-bearing structures and impact-resistant components because of their distinctive physical and chemical properties. Accurate predictions and assessment of the mechanical responses of glass structures are crucial for structural design and reliability analysis. In this study, quasi-static and dynamic ball-on-ring (BOR) biaxial flexural tests are conducted on aluminosilicate glass. The smeared fixed crack model is calibrated for deformation and failure analyses. First, the model parameters are calibrated carefully, particularly for different failure criteria. Both the deformation field and fracture modes agree well with the experimental observations during the quasi-static tests. For the low-velocity impact biaxial flexural loading condition, three different numerical techniques, namely the initial scaling tensile strength criterion, non-local approach with energy criterion, and rate-dependent failure stress criterion, are implemented in the numerical models for dynamic failure analysis. Finally, the proposed smeared fixed crack model is compared with the widely used Johnson Holmquist Ⅱ (JH-2) model and demonstrates advantages for low-velocity impact response analysis of glass structures.

Multiaxial creep deformation investigation of miniature cruciform specimen for type 304 stainless steel at 923 K using non-contact displacement-measuring method

Abstract Multiaxial creep investigations at high temperatures are required to guarantee the integrity of structural materials such as boiler pipes for power generation and turbine blades for aviation and industrial applications. The multiaxial creep testing method using a cruciform specimen has several advantages, and the authors successfully downsized the specimen. The authors also developed a technique for the in situ observation of the specimen in an electric furnace and the non-contact displacement measurement in the development of a biaxial tensile creep testing machine for the miniature cruciform specimen. By observing the specimen at a target mark during the creep testing through an observation window installed at the bottom of the furnace, it was possible to visualize the specimen surface variations and obtain the axial strain from the locus of the target marks. The Mises-type equivalent strain was calculated from the axial strains obtained in the equi-biaxial tensile multiaxial creep testing and was compared with the strains obtained in the uniaxial creep testing. The Mises-type equivalent strain can be expressed using a unified method up to approximately 5% of the initial strain in the test, even in the multiaxial stress state.

Finite Element Simulation of Opening Angle Response of Porcine Aortas Using Layer Specific GAG Distributions in One and Two Layered Solid Matrices.

Recent studies have identified an effect of glycosaminoglycans (GAG) on residual stresses in the aorta,underscoring the need to better understand their biomechanical roles. Aortic ring models for each of the ascending, arch and descending thoracic regions of the porcine thoracic aorta were created in FEBioStudio, using a framework that incorporates the Donnan osmotic swelling in a porous solid matrix. The distribution of fixed charge densities (FCD) through the thickness of the tissue was prescribed as calculated from experimentally quantified sulfated GAG mural distributions. Material parameters for the solid matrix, modeled using a Holmes-Mow constitutive law, were optimized using data from biaxial tensile tests. In addition to modelling the solid matrix as one layer, two layers were considered to capture the differences between the intima-media and the adventitia, for which various stiffness ratios were explored. As the stiffness of the adventitia with respect to that of the media increased, the simulated opening angle increased. The opening angle also decreased from the ascending to the descending thoracic region in both one- and two-layered solid matrices models. The simulated results were compared against the experimental contribution of GAG to the opening angle, as previously quantified via enzymatic GAG-depletion.When using one layer for the solid matrix, the errors between the simulated opening anglesand the experimental contribution of GAG to the opening anglewere respectively 28%, 15% and 23% in the ascending, arch and descending thoracic regions. When using two layers for the solid matrix, the smallest errors in the ascending and arch regions were 21% and 5% when the intima-media was modelled as 10 times stiffer, and as twice stiffer than the adventitia, respectively, and 23% in the descending thoracic regions when the intima-media and adventitia shared similar mechanical properties. Overall, this study demonstrates that GAG partially contribute to circumferential residual stress, and that GAG swelling is one of several regulators of the opening angle. The minor discrepancies between simulated and experimental opening angles imply that the contribution of GAG extends beyond mere swelling, aligning with previous experimental indications of their interaction with ECM fibers in determining the opening angle.

Effect of symmetrical biaxial tension on the magnetic properties of the composite specimen of two steel plates with different mechanical and magnetic properties

The results of studying the behavior of the magnetic characteristics of two-layer material containing layers of annealed sheet low-carbon Steel 15 and sheet metastable austenitic 12Kh18N9Т steel, subjected to cold rolling with a compression of 50 %, under biaxial symmetric tension have been presented. Experiments on biaxial deformation were carried out on the original biaxial testing machine, allowed to determine the physical properties of materials during elastic-plastic deformation independently along two axes. It has been shown that the coercive force of the studied two-layer material vary monotonically over the entire range of elastic-plastic biaxial deformation and can be used as an informative parameter for assessing the it’s stresses and deformations.

Automated model discovery for textile structures: The unique mechanical signature of warp knitted fabrics

Textile fabrics have unique mechanical properties, which make them ideal candidates for many engineering and medical applications: They are initially flexible, nonlinearly stiffening, and ultra-anisotropic. Various studies have characterized the response of textile structures to mechanical loading; yet, our understanding of their exceptional properties and functions remains incomplete. Here we integrate biaxial testing and constitutive neural networks to automatically discover the best model and parameters to characterize warp knitted polypropylene fabrics. We use experiments from different mounting orientations, and discover interpretable anisotropic models that perform well during both training and testing. Our study shows that constitutive models for warp knitted fabrics are highly sensitive to an accurate representation of the textile microstructure, and that models with three microstructural directions outperform classical orthotropic models with only two in-plane directions. Strikingly, out of 214=16,384 possible combinations of terms, we consistently discover models with two exponential linear fourth invariant terms that inherently capture the initial flexibility of the virgin mesh and the pronounced nonlinear stiffening as the loops of the mesh tighten. We anticipate that the tools we have developed and prototyped here will generalize naturally to other textile fabrics–woven or knitted, weft knit or warp knit, polymeric or metallic–and, ultimately, will enable the robust discovery of anisotropic constitutive models for a wide variety of textile structures. Beyond discovering constitutive models, we envision to exploit automated model discovery for the generative material design of wearable devices, stretchable electronics, and smart fabrics, as programmable textile metamaterials with tunable properties and functions. Our source code, data, and examples are available at https://github.com/LivingMatterLab/CANN. Statement of significanceTextile structures are rapidly gaining popularity in many biomedical applications including tissue engineering, wound healing, and surgical repair. A precise understanding of their unique mechanical properties is critical to tailor them to their specific functions. Here we integrate mechanical testing and machine learning to automatically discover the best models for knitted polypropylene fabrics. We show that warp knitted fabrics possess a complex symmetry with three distinct microstructural directions. Along these, the behavior is dominated by an exponential linear term that characterize the initial flexibility of the virgin mesh and the nonlinear stiffening as the loops of the fabric tighten. We expect that our technology will generalize naturally to other fabrics and enable the robust discovery of complex anisotropic models for a wide variety of textile structures.

Age- and sex-specific biomechanics and extracellular matrix remodeling of the ascending aorta in a mouse model of severe Marfan syndrome.

Thoracic aortic aneurysm (TAA) is associated with Marfan syndrome (MFS), a connective tissue disorder caused by mutations in fibrillin-1. Sexual dimorphism has been recorded for TAA outcomes in MFS, but detailed studies on the differences in TAA progression in males and females and their relationships to outcomes have not been performed. The aims of this study were to determine sex differences in the diameter dilatation, mechanical properties, and extracellular matrix (ECM) remodeling over time in a severe mouse model (Fbn1mgR/mgR = MU) of MFS-associated TAA that has a shortened life span. Male and female MU and wildtype (WT) mice were used at 1-4 mo of age. Blood pressure and in vivo diameters of the ascending thoracic aorta were recorded using a tail-cuff system and ultrasound imaging, respectively. Ex vivo mechanics and ECM remodeling of the aorta were characterized using a biaxial test system and multiphoton imaging, respectively. We showed that mechanical properties, such as structural and material stiffness, and ECM remodeling, such as elastic and collagen fiber content, correlated with diameter dilatation during TAA progression. Male MU mice had accelerated rates of diameter dilatation, stiffening, and ECM remodeling compared with female MU mice which may have contributed to their decreased life span. The correlation of mechanical properties and ECM remodeling with diameter dilatation suggests that they may be useful biomarkers for TAA progression. The differences in diameter dilatation and life spans in male and female MU mice indicate that sex is an important consideration for managing thoracic aortic aneurysm in MFS. NEW & NOTEWORTHY Using a mouse model (Fbn1mgR/mgR = MU) of severe thoracic aortic aneurysm in Marfan syndrome (MFS), we found that male MU aorta had an accelerated time line and increased amounts of dilatation, stiffening, and extracellular matrix (ECM) remodeling compared with female MU aorta that may have contributed to an increased risk of fatigue failure with cyclic loading over time and a reduced life span. We suggest that aortic stiffness may provide useful information for clinical management of aneurysms in MFS.

Experimental investigations on the failure characteristics of the slit-contained circular opening under biaxial compression: Insights into the rockburst prevention

The slit-cut method for the rockburst prevention and control is believed effective with its easiness in operation, adjustment and compatibility. However, there is limited advance knowledge of the physics of the slit-cut method, which is vital for the engineering designs. In this study, the biaxial compression tests with a synchronous AE (acoustic emission)-DIC (digital image correlation) monitoring are creatively carried out on the slit-contained circular opening specimens with different slit configurations to demonstrate the academic thoughts and mechanisms of the slit-cut method. The experiments document the two typical failure types namely the internal crack propagation and the dynamic rockburst, which occupy different AE hit rate characteristics and different entropy properties. With the occurrence of rockburst, the AE hit rate presents a bouncing ascend-descend trend, and a higher disorder and chaos is faithfully exhibited. Depending on the slit parameters, the slit-cut method can efficiently mitigate rockburst in terms of the occurrence frequency and magnitude. The underlying mechanism lies in the enhancement of the shear mechanism and the development of the internal cracks through which the stored energy can be greatly dissipated. However, due to the unrestricted shear failure in the slit-contained opening specimens, the opening-scale inward instability can be triggered by the internal crack coalescence, thus posing a threat to the safety of the opening. Implementing the slit-cut method with a consideration of the in-situ stress conditions is evidently essential for the safe excavation.

A viscoelastic constitutive framework for aging muscular and elastic arteries

The evolution of arterial biomechanics and microstructure with age and disease plays a critical role in understanding the health and function of the cardiovascular system. Accurately capturing these adaptative processes and their effects on the mechanical environment is critical for predicting arterial responses. This challenge is exacerbated by the significant differences between elastic and muscular arteries, which have different structural organizations and functional demands. In this study, we aim to shed light to these adaptive processes by comparing the viscoelastic mechanics of autologous thoracic aortas (TA) and femoropopliteal arteries (FPA) in different age groups. We have extended our fractional viscoelastic framework, originally developed for FPA, to both types of arteries. To evaluate this framework, we analyzed experimental mechanical data from TA and FPA specimens from 21 individuals aged 13 to 73 years. Each specimen was subjected to a multi-ratio biaxial mechanical extension and relaxation test complemented by bidirectional histology to quantify the structural density and microstructural orientations. Our new constitutive model accurately captured the mechanical responses and microstructural differences of the tissues and closely matched the experimentally measured densities. It was found that the viscoelastic properties of collagen and smooth muscle cells (SMCs) in both the FPA and TA remained consistent with age, but the viscoelasticity of the SMCs in the FPA was twice that of the TA. Additionally, changes in collagen nonlinearity with age were similar in both TA and FPA. This model provides valuable insights into arterial mechanophysiology and the effects of pathological conditions on vascular biomechanics. Statement of significanceDeveloping durable treatments for arterial diseases necessitates a deeper understanding of how mechanical properties evolve with age in response to mechanical environments. In this work, we developed a generalized viscoelastic constitutive model for both elastic and muscular arteries and analyzed both the thoracic aorta (TA) and the femoropopliteal artery (FPA) from 21 donors aged 13 to 73. The derived parameters correlate well with histology, allowing further examination of how viscoelasticity evolves with age. Correlation between the TA and FPA of the same donors suggest that the viscoelasticity of the FPA may be influenced by the TA, necessitating more detailed analysis. In summary, our new model proves to be a valuable tool for studying arterial mechanophysiology and exploring pathological impacts.

Towards high-strength electrolyte-supported solid oxide fuel cells

The functionality and structural reliability of electrolyte-supported solid oxide fuel cells depend crucially upon the load-bearing capability of the ceramic electrolyte. In this work, the effect of thickness on the mechanical strength of tape-casted 8 mol% yttria-stabilized zirconia electrolyte discs was investigated. Samples with 98 % relative density and 2–3 µm grain size fabricated with thicknesses between 75 µm and 360 µm were mechanically tested using an adapted biaxial bending test. Thin electrolytes with biaxial strength up to 1 GPa could be produced. The measured characteristic strengths ranged from σ0 = 940 MPa to σ0 = 520 MPa for thin and thick samples, respectively, yielding a common Weibull modulus of m = 6. A higher strength scaled with decreasing thickness, confirming the “size effect” as in many technical ceramics. The measured ionic conductivity was above 0.1 S/cm at 1000 °C, which is in good agreement with commercial or conventionally prepared electrolytes.

Horizontal Test Stand for Bone Screw Insertion

Screws are a versatile method of fixation and are often used in orthopaedic surgery. Various specialised geometries are often used for bone screws to optimise their fixation strengths in limited spaces at the expense of manufacturing costs. Additionally, ongoing research is looking to develop systems/models to automatically optimise bone screw tightening torques. For both applications, it is desirable to have a test rig for inserting screws in a regulated, instrumented, and repeatable manner. This work presents such a test rig primarily used for the validation of optimal torque models; however, other applications like the above are easily foreseeable. Key features include controllable insertion velocity profiles, and a high rate measurement of screw torque, angular displacement, and linear displacement. The test rig is constructed from mostly inexpensive components, with the primary costs being the rotational torque sensor (approx. 2000 €), and the remainder being approximately 1000 €. This is in comparison to a biaxial universal testing machine which may exceed 100,000 €. Additionally, the firmware and interface software are designed to be easily extendable. The angular velocity profiling and linear measurement repeatability of the test rig is tested and the torque readings are compared to an off-the-shelf static torque sensor.

Tissue expansion mitigates radiation-induced skin fibrosis in a porcine model

Tissue expansion (TE) is the primary method for breast reconstruction after mastectomy. In many cases, mastectomy patients undergo radiation treatment (XR). Radiation is known to induce skin fibrosis and is one of the main causes for complications during post-mastectomy breast reconstruction. TE, on the other hand, induces a pro-regenerative response that culminates in growth of new skin. However, the combined effect of XR and TE on skin mechanics is unknown. Here we used the porcine model of TE to study the effect of radiation on skin fibrosis through biaxial testing, histological analysis, and kinematic analysis of skin deformation over time. We found that XR leads to stiffening of skin compared to control based on a shift in the transition stretch (transition between a low stiffness and an exponential stress-strain region characteristic of collagenous tissue) and an increase in the high modulus (modulus computed with stress-stretch data past the transition point). The change in transition stretch can be explained by thicker, more aligned collagen fiber bundles measured in histology images. Skin subjected to both XR+TE showed similar microstructure to controls as well as similar biaxial response, suggesting that physiological remodeling of collagen induced by TE partially counteracts pro-fibrotic XR effects. Skin growth was indirectly assessed with a kinematic approach that quantified increase in permanent area changes without reduction in thickness, suggesting production of new tissue driven by TE even in the presence of radiation treatment. Future work will focus on the detailed biological mechanisms by which TE counteracts radiation induced fibrosis. Statement of significanceBreast cancer is the most prevalent in women and its treatment often results in total breast removal (mastectomy), followed by reconstruction using tissue expanders. Radiation, which is used in about a third of breast reconstruction cases, can lead to significant complications. The timing of radiation treatment remains controversial. Radiation is known to cause immediate skin damage and long-term fibrosis. Tissue expansion leads to a pro-regenerative response involving collagen remodeling. Here we show that tissue expansion immediately prior to radiation can reduce the level of radiation-induced fibrosis. Thus, we anticipate that this new evidence will open up new avenues of investigation into how the collagen remodeling and pro-regenerative effects of tissue expansion can be leverage to prevent radiation-induced fibrosis.

Glenoid component cyclical failure decreases with increasing baseplate contact: a biomechanical study

BackgroundGlenoid baseplate loosening remains a common mode of failure in reverse shoulder arthroplasty. One of the key factors to baseplate stability is theorized to be maximization of baseplate backside contact. The purpose of this biomechanical study is to investigate the role of varying degrees of backside bony glenoid support in component stability for reverse total shoulder arthroplasty. MethodsTwenty synthetic scapular models were divided into 3 test groups of 5 scapulae with glenoid baseplate contacts of 40%, 60%, and 75%, and one control group with glenoid baseplate contact of 100%. Standardized application of a commercially available glenoid baseplate and glenosphere was performed. The scapulae were mounted on a linear bearing with a humeral component and polyethylene liner which were affixed to a biaxial servohydraulic fatigue testing system. Each specimen was loaded for 10,000 cycles or to failure, about a 55° arc along the glenosphere at a rate of 1 Hz as a 750 N compression load was applied. Failure was defined as fracture of the scapula with implant fixation compromise. Before and after loading, stability of the baseplate was assessed by quantifying the total motion between the model and the baseplate with digital calipers as a ramp load between 0 and 150 N was applied. Two-sample unpaired t-tests were performed with significance set at P < .05. ResultsBaseplate contacts of 40% (1623 ± 227, P = .0001), 60% (3299 ± 1170, P = .0001), and 75% (5615 ± 1587, P = .0077) demonstrated statistically significant decrease in the average number of cycles to failure in all cohorts compared to our control (8641 ± 1070). Cycles taken for initial cracks to progress to failure showed no significant differences; 40% contact (862 ± 452, P = .4751), 60% contact (1651 ± 996, P = .4318), 75% contact (2882 ± 1347, P = .0620), and 100% control (1166 ± 657). Baseplate contacts of 40% (6150.4 ± 444.0, P = .0006), 60% (4647.1 ± 552.3, P = .0072), and 75% (2927.8 ± 918.5, P = .2573) demonstrated increasing micromotion (pre-post cyclical loading) in all cohorts compared to our control (2074.7 ± 1164.6) with statistical significance at 40% and 60%. ConclusionThese biomechanical tests demonstrate that decreasing glenoid baseplate backside contact leads to increased micromotion and fewer cycles to failure. This supports the surgical goal of achieving maximal glenoid baseplate backside contact, suggesting that decreased glenoid baseplate support could contribute to significant loosening.

The impact of aging and thickness on flexural strength of various zirconia ceramics

BackgroundEffects of the aging process on the flexural strength of Y-TZP and different Y-PSZ ceramics of different thicknesses were investigated.Methods300 disc-shaped samples (12 mm diameter, 0.8 and 1.5 mm thicknesses) were made from 5 different zirconia materials 3Y-TZP LA, 4Y-PSZ, 5Y-PSZ, 3 + 5Y-PSZ and 4 + 5Y-PSZ. Experimental groups were artificially aged in an autoclave at 134 °C, 2 bar pressure for 1 and 5 h; control groups were not subjected to any treatment. Microstructural analysis was conducted using Scanning Electron Microscopy, and X-Ray Diffraction analysis determined the crystalline phase content. The impact of aging on flexural strength was investigated with the use of the biaxial flexural strength test. Data were analyzed using three-way ANOVA tests with a significance level of p < 0.05, applying Bonferroni correction for multiple comparisons.ResultsStatistically significant differences in flexural strength were observed among the materials and the material thicknesses (p < 0.05), while there were no significant differences among the aging times (p > 0.05). The highest mean flexural strength values were recorded in the case of the 3 Y-TZP-1.5 mm–5 h group (744.1 ± 61.2 MPa), which was attributed to phase-transformation toughening. The lowest values were observed in the case of the 5 Y-PSZ-1.5 mm–5 h (338.3 ± 34.8 MPa) group.ConclusionsBoth material type and thickness significantly affect the flexural strength of zirconia ceramics, whereas aging time does not; thus, material selection and thickness are crucial considerations for clinicians.

Study on crack propagation mechanism and acoustic-thermal sensitivity analysis of pre-cracked weakly cemented rock

As the intensity and depth of coal mining gradually increase, environmental disturbances become more complex, and the degree of crack development in weakly cemented surrounding rocks continues to increase. In order to study the influence mechanism of crack angle on the fracture mechanism and acoustic − thermal precursor information of weakly cemented rocks, visual biaxial loading tests were conducted on pre-cracked weakly cemented rocks based on a transparent servo loading device, combined with digital speckle correlation method (DSCM), acoustic emission (AE), and infrared thermal imaging (ITI). The research results indicate that as the inclination angle of cracks increases, the initial strength, peak strength, and elastic modulus of rocks exhibit a logarithmic relationship of first decreasing and then increasing. When the inclination angle of the crack increases from < 30° to > 75°, the failure mode of weakly cemented rocks changes from shear to tension. The propagation path of deformation localization is consistent with the propagation trajectory of surface cracks, and the extension length and time of tensile cracks are longer than those of shear cracks. The acoustic − thermal sensitivity of weakly cemented rocks with crack inclination angle of > 45° is higher than that with crack inclination angle of ≤ 30°. The research results contribute to further understanding and mastering the mechanism of crack initiation and propagation in weakly cemented rocks containing joints, and provide theoretical guidance for engineering methods to control the deformation of weakly cemented surrounding rocks.

Democratizing biomedical simulation through automated model discovery and a universal material subroutine

AbstractPersonalized computational simulations have emerged as a vital tool to understand the biomechanical factors of a disease, predict disease progression, and design personalized intervention. Material modeling is critical for realistic biomedical simulations, and poor model selection can have life-threatening consequences for the patient. However, selecting the best model requires a profound domain knowledge and is limited to a few highly specialized experts in the field. Here we explore the feasibility of eliminating user involvement and automate the process of material modeling in finite element analyses. We leverage recent developments in constitutive neural networks, machine learning, and artificial intelligence to discover the best constitutive model from thousands of possible combinations of a few functional building blocks. We integrate all discoverable models into the finite element workflow by creating a universal material subroutine that contains more than 60,000 models, made up of 16 individual terms. We prototype this workflow using biaxial extension tests from healthy human arteries as input and stress and stretch profiles across the human aortic arch as output. Our results suggest that constitutive neural networks can robustly discover various flavors of arterial models from data, feed these models directly into a finite element simulation, and predict stress and strain profiles that compare favorably to the classical Holzapfel model. Replacing dozens of individual material subroutines by a single universal material subroutine—populated directly via automated model discovery—will make finite element simulations more user-friendly, more robust, and less vulnerable to human error. Democratizing finite element simulation by automating model selection could induce a paradigm shift in physics-based modeling, broaden access to simulation technologies, and empower individuals with varying levels of expertise and diverse backgrounds to actively participate in scientific discovery and push the boundaries of biomedical simulation.