As one of the chapters in the International Roadmap of Device and Systems (IRDS), the “Beyond CMOS (BC)” roadmap surveys and catalogs emerging devices and materials, and evaluate their potential and challenges gating their acceptance by the industry. While CMOS is expected to continue to dominate as the platform technology, beyond-CMOS devices may enable novel computing paradigms and efficient hardware accelerators to augment the CMOS platform. Emerging device-architecture co-design and co-optimization are important for achieving the efficiency and functionalities beyond the limit of CMOS technologies. This paper provides a brief overview of the IRDS BC chapter, with the emphasis on the opportunities of beyond-CMOS devices and architectures for neuro-inspired computing paradigms.