Betulin Research Articles

Production of Triterpenes from Cell Suspension Cultures of Solanum incanum L.

This paper describes the secondary metabolites produced by a cell suspension culture of Solanum incanum L. The investigation led to the characterization of five triterpenes, glut-5(6)-en-3β-ol (1), lupeol (2), betulin (3), betulinic acid (4) and betulinaldehyde (5). Their structures were determined on the basis of spectral analysis. Of these, betulinic acid, a potent anti-HIV agent, was found to be a major product. Glut-5(6)-en-3β-ol was a rare natural product.

On the Constitution of Betulin and Lupeol

On the Constitution of Betulin and Lupeol