Background: The COVID-19 pandemic has been affecting all over the world; medical students are a successor force, providing great support to the prevention of the COVID-19 pandemic. Objectives: to assess the completeness of knowledge, attitudes, and practices of COVID19 prevention as well as utilize factors influencing the good practices of medical students at Can Tho University of Medicine and Pharmacy. Materials and methods: A 2-week cross-sectional study (from October 1 to October 15, 2021) was conducted among 729 of 4th and 6th – year medical students at Can Tho University of Medicine and Pharmacy through an online survey with a set of 36 questions. Results: The score of the Fear of COVID-19 Scale was moderately high (17.61±4.55). The percentage of students with good general knowledge (overall score ≥11) was 56.2%. Approximately 97.5% of the participants had positive attitudes about complying with disease prevention measures. There were 94.2% of students had good practices with preventive measures. The study showed that 2 factors related to good practices were good sufficient knowledge and positive attitudes (p<0.05). Students with sufficient knowledge and positive attitudes performed better than students with insufficient knowledge and negative attitudes by 2.4 times (95% confidence interval: 1.18-4.8) and 7.2 times (95% confidence interval: 2.5-21.9), respectively. Conclusions: The majority of students had enough knowledge (56.2%), positive attitudes (97.5%) and good practices (94.2%) in COVID-19 prevention. High FCV-19S, females, sufficient knowledge, and positive attitudes had a significant correlation with good practices.
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