The fade-in and fade-out algorithm based on the Bernstein polynomial has certain limitations in image fusion. Therefore, this article proposes a new image fusion algorithm. First, the SIFT algorithm is used to register the images. Second, for the disjointed case of overlapping regions, a progressive image mosaic fusion algorithm in the form of a sine function is proposed. Finally, in order to make the progressive image mosaic fusion algorithm suitable for a variety of overlapping regions, this paper adds segmentation technology. The simulation experiment results show that the algorithm proposed in this paper is in good agreement with the spatial details and texture details of a high-resolution panchromatic image, and the time is shorter, which meets the real-time requirements. In addition, the algorithm proposed in this paper is effective in applications such as virtual reality and art image fusion.