Functional Benefits Research Articles

Custom silicone Y-stents for the management of anastomotic stenosis in lung transplant recipients

BackgroundAirway stenting may be needed to manage anastomotic complications in lung transplant recipients. Conventional stenting strategies may be inadequate due to anatomic variations between the recipient and donor or involvement of both the anastomosis and lobar bronchi. MethodsWe investigated the efficacy of 3D-designed patient-specific silicone Y-stents in managing this scenario. 9 patients with complex airway stenosis underwent custom stent insertion after either failing traditional management strategies or having anatomy not suitable for conventional stents. CT images were uploaded to stent design software to make a virtual stent model. 3D printing technology was then used to make a mold for the final silicone stent which was implanted via rigid bronchoscopy. Forced expiratory volume in 1 s (FEV1) was measured pre- and post-stent placement. Results78 % of patients experienced an increase in their FEV1 after stent insertion, (p = 0.001, 0.02 at 30 and 90 days respectively). Unplanned bronchoscopies primarily occurred due to mucous plugging. 2 patients had sufficient airway remodeling allowing for stent removal. ConclusionsPersonalized 3D-designed Y-stents demonstrate promising results for managing complicated airway stenosis, offering improved lung function and potential long-term benefits for lung transplant recipients.

What drives the adoption of digital technology in the micro, small, and medium enterprises sector in a developing economy?

PurposeThis study aims to explore the determinants of digital technology adoption within micro, small and medium enterprises (MSMEs) operating in a developing economy. Grounded in the theoretical frameworks of fit-viability and task-technology fit models, this study investigates the impact of environmental fit, task-technology fit and viability on the intention to adopt digital technologies among MSMEs.Design/methodology/approachThis study validates the theoretical model using structural equation modeling, using data collected from 280 experienced respondents employed in the MSMEs in India.FindingsThe results indicate that both functional and symbolic benefits positively impact managers’ intention to adopt digital technology. However, subgroup analysis reveals that in the case of service enterprises, only functional benefits have a positive influence on managers’ intention to adopt digital technology. In addition, the findings underscore the crucial role of viability in shaping the intention to adopt digital technologies among MSMEs. This study highlights how functional and symbolic benefits motivate digital technology adoption in MSMEs.Originality/valueThere is a dearth of empirical studies investigating the factors influencing the adoption of digital technology by MSME firms, especially within the context of developing economies and specifically within the MSME domain. This study contributes to the theoretical discussion surrounding digital technology adoption among MSMEs in India. Through empirical research, it expands on the fit-viability model and formulates a technology adoption model within the MSME context.

Quality changes in high hydrostatic pressure treated enriched tomato sauce.

Use of high hydrostatic pressure (HHP) with reduced processing times is gaining traction in the food industry as an alternative to conventional thermal treatment. In order to enhance functional benefits while minimizing processing losses, functionalized products are being developed with such novel techniques. In this study, changes in quality parameters for HHP treated enriched tomato sauce were evaluated, with the aim to assess its viability as an alternative to conventional thermal treatment methods. HHP treatments at 500 MPa, 30 °C/50 °C significantly increased the total phenolic and lycopene content of the sauce samples, achieving 6.7% and 7.5% improvements over conventionally treated samples. The antioxidant capacity of the HHP-treated samples was also found to match or be better than conventionally treated samples. Furthermore, a T2 relaxation time study revealed that pressure-temperature processing treatments were effective in maintaining the structural integrity of water molecules. Microbiological analyses revealed that 500 MPa/50 °C 5 min treatment can offer 8 logs reduction colony formation, matching the results of conventional thermal treatment. Combined pressure-temperature treatments improve results, reduce time consumption. 500 MPa/50 °C treatments provided retention of quality parameters and significant reduction in microbial activity. © 2024 The Author(s). Journal of The Science of Food and Agriculture published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.

Assessment of oat (Avena sativa) varieties unveiled the variation in nutritional quality

The present study was carried out during 2022 at Punjab Agricultural University, Ludhiana, Punjab designed for the exploration and characterization of different oat varieties to understand their potential for physical, gravitational, functional, nutritional, and extraction of β-glucan parameters. All studied varieties showed variability in the grain and flour quality of oats. The preference of a variety based on nutritional and functional parameters contingent on this evaluation could help a satisfactory basis for future oat crop improvement plans for feed and food security. The current scientific intervention suggests that oat variety OL 1876-2 might be a suitable choice for β-glucan extraction due to its high content with promising nutritional and functional benefits. These findings may open a new avenue for further research on utilization of oats for food purpose that could cater the imminent demands of health conscious people.

Cervicothoracic ventral-dorsal rhizotomy for treatment of brachial hypertonia in cerebral palsy

PurposeCervicothoracic ventral-dorsal rhizotomy (VDR) is a potential treatment of medically refractory hypertonia in patients who are not candidates for intrathecal baclofen, particularly in cases of severe upper limb hypertonia with limited to no function. A longitudinal cohort was identified to highlight our institutional safety and efficacy using cervicothoracic VDR for the treatment of hypertonia.MethodsRetrospective data analysis was performed for patients that underwent non-selective cervicothoracic VDR between 2022 and 2023. Non-modifiable risk factors, clinical variables, and operative characteristics were collected.ResultsSix patients (three female) were included. Four patients underwent a bilateral C6-T1 VDR, one patient underwent a left C7-T1 VDR, and another underwent a left C6-T1 VDR. Three patients had quadriplegic mixed hypertonia, one patient had quadriplegic spasticity, one patient had triplegic mixed hypertonia, and one patient had mixed hemiplegic hypertonia. The mean difference of proximal upper extremity modified Ashworth scale (mAS) was − 1.4 ± 0.55 (p = 0.002), and − 2.2 ± 0.45 (p < 0.001) for the distal upper extremity. Both patients with independence noted quality of life improvements as well as increased ease with dressing and orthotics fits. Caregivers for the remaining four patients noted improvements in caregiving provision, mainly in dressing, orthotics fit, and ease when transferring.ConclusionCervicothoracic VDR is safe and provides tone control and quality of life improvements in short-term follow-up. It can be considered for the treatment of refractory hypertonia. Larger multicenter studies with longer follow-up are necessary to further determine safety along with long-term functional benefits in these patients.

Characterization of Probiotic Potential Lactic Acid Bacteria Isolated from Chinese Cabbage Brassica rapa subsp. Pekinensis

ABSTRACT This study aimed to isolate and evaluate the probiotic potential of lactic acid bacteria (LAB) from Chinese cabbage (Brassica rapa subsp. pekinensis) that is typically used in Kimchi, a Korean fermented product. Lactococcus lactis VLC.1 and VLC.2, and Lactococcus garvieae VLC.3 were identified and further assessed for their probiotic properties. These strains exhibited biological activity such as antioxidant capabilities, antimicrobial activity against pathogenic bacteria, hydrophobicity, and co-aggregation. These findings suggest their potential as probiotics to alleviate oxidative stress and maintain gastrointestinal flora balance. Significantly, the cell-free supernatants derived from LAB isolates exhibited synergistic antimicrobial activity with effectiveness against Escherichia coli, providing novel strategies to address antibiotic resistance challenges. The LAB isolates showed no antibiotic resistance and lacked hemolytic activity, underscoring their safety and efficacy as probiotics. In summary, our findings contribute valuable insights into the biological and safety properties of LAB strains isolated from Chinese cabbage, highlighting their functional benefits.

Sensori-motor neurofeedback improves inhibitory control and induces neural changes: a placebo-controlled, double-blind, event-related potentials study

Background/ObjectiveInhibition is crucial for controlling behavior and is impaired in various psychopathologies. Neurofeedback holds promise in addressing cognitive deficits, and experimental research is essential for identifying its functional benefits. This study aimed to investigate whether boosting sensorimotor activity (SMR) improves inhibitory control in a final sample of healthy individuals (N = 53), while exploring the underlying neurophysiological mechanism. MethodParticipants were randomly divided into two groups: one receiving SMR neurofeedback training to enhance sensorimotor activity within the 12–15 Hz frequency range, and the other receiving sham feedback. Inhibition performance and neural correlates were evaluated with a Go-NoGo task before (T0) and after (T1) 10 neurofeedback sessions using event-related potentials. Data were analyzed via ANOVAs and regression analyses. ResultsCompared to placebo, the active group demonstrated higher absolute SMR power (p = 0.040) and improvements in inhibitory control, including faster response times and fewer inhibition errors (p < 0.001, d = 6.06), associated with a larger NoGoP3d amplitude (p < 0.001, d = 3.35). A positive correlation between the increase in SMR power and the rise in NoGoP3d amplitude (β=0.46, p = 0.015) explains 21 % of the observed variance. ConclusionsUptraining SMR power is linked to heightened utilization of neural resources for executing optimal inhibition responses. These results uphold its effectiveness in cognitive rehabilitation.

When regulation ignores evidence: The case of Denmark’s Ashwagandha ban and the Technical University of Denmark’s misguided risk assessment

The recent ban on Ashwagandha (Withania somnifera (L.) Dunal) supplements in Denmark, based on a risk assessment by the Technical University of Denmark (DTU), exemplifies the challenges in regulating traditional herbal medicines within modern frameworks. This article critically examines the DTU report, highlighting methodological flaws including overreliance on animal studies and selective literature review. The report’s disregard for Ashwagandha's long history of traditional use and mischaracterization of its effects, particularly alleged abortifacient properties, contradicts a growing body of scientific evidence supporting its safety and efficacy. The current research demonstrating Ashwagandha's benefits in stress reduction, sleep improvement, and cognitive function further underscores the disparity between scientific findings and the DTU’s conclusions. The ban’s implications extend beyond Denmark, raising questions about regulatory consistency and proportionality in evaluating herbal products globally. The Indian Ministry of Ayush’s critique emphasizes the need for a more comprehensive, evidence-based approach for assessing traditional medicines. This controversy may catalyze the development of integrated evaluation methods, such as the Collaborative Medicine and Science framework, bridging diverse knowledge systems in regulatory decision-making. The case underscores the necessity for a global health paradigm that harmonizes traditional and modern medical approaches, ensuring public safety while preserving access to beneficial traditional remedies.

Disparities in pathways to reduction mammaplasty: A single institution review of 425 women with macromastia

BackgroundReduction mammaplasty improves the quality of life by providing functional and aesthetic benefits to women with macromastia. This study contributes to the existing literature on socioeconomic and clinical barriers to referral for plastic surgery procedures by focusing specifically on reduction mammaplasty. MethodsPatients with macromastia were identified via a chart review in a single institution from 2021–2022. The treatment pathway for each patient was characterized by reception of referral, completion of plastic surgery consultation, and eventual reception of surgery. After controlling for clinical covariates, multivariate logistic regression was applied to quantify the independent impact of race, insurance, and language status on the completion of surgery (p < 0.05). ResultsThe final patient cohort included 425 women with macromastia. Among the 151 patients who were first seen by a primary care physician, 64 (42%) completed an initial plastic surgery consultation. Among all patients, 160 (38%) eventually underwent reduction mammaplasty. Multivariate regression predictions indicated a lower likelihood of completing breast reduction surgery in patients with current smoking history (OR: 0.08, 95% CI: 0.01–0.59) and higher body mass index (BMI) (OR: 0.94, 95% CI: 0.90–0.97) (p < 0.05). Minority race and ethnicity, private insurance status, and primary language status were not significant predictors of this outcome (p > 0.05). ConclusionsIn this study, the socioeconomic variables were not independent predictors of breast reduction surgery completion. However, the association of minority race and ethnicity and nonprivate insurance status with the most common reasons for breast reduction deferral suggest an indirect influence of socioeconomic status on the treatment pathway.

NATURE EMULATING GLAZES IN CERAMICS: THE HISTORY OF CRATER GLAZES, DEVELOPING AND COLORING

NATURE EMULATING GLAZES IN CERAMICS: THE HISTORY OF CRATER GLAZES, DEVELOPING AND COLORING Abstract Glazes applied to the surfaces of ceramic bodies sometimes provide functional benefits and sometimes make aesthetic contributions. Especially the colour and texture diversity of the glazes used in art ceramics makes ceramic forms aesthetically richer and more interesting. In this sense, artists who have mastered the technology of ceramics can produce glazes with their own recipes and use them as a personal language in their works of art. This possibility of creating an identity that the material gives to the artist has paved the way for the production of endless variations of glazes with organic and inorganic additives over time. Crater glazes, named after the term "crater" that emerges as a result of natural formations on the earth due to the similarity of its textural appearance, can be produced by adding silicon carbide (SiC), an inorganic substance, to the glaze. Silicon carbide, which creates a blistering effect, which is accepted as a defect in the glaze, shows that a defect can also make an aesthetic contribution with the crater image that appears when it is prescribed in appropriate proportions. In this article, the historical background of crater glazes is investigated, glossy and matte crater glazes are discussed and experimental applications are carried out with colouring alternatives. Keywords: Ceramics, Glaze, Crater, Lava, Silicon Carbide.

Sensory Response of Durian Lai Tempoyak and Its Potential as A Functional Food

Tempoyak, a fermented food made from durian, is a popular seasoning in Malay communities in Malaysia and Indonesia. Produced using low-quality durian, it serves as an alternative to prevent spoilage. Tempoyak has functional benefits as it contains lactic acid bacteria (LAB), a probiotic providing digestive health benefits. Research on East Kalimantan's durian lai explores its potential for tempoyak production. The study, utilizing a Completely Randomized Design, examined salt concentrations and fermentation times. Optimal quality was achieved with a 5% salt concentration and a 7-day fermentation period, yielding favorable organoleptic results, with "liked" ratings for color and texture, and "somewhat liked" for aroma and taste. The hedonic quality included an orange-yellow color, sour aroma, salty taste, and soft texture. The total LAB reached 4.1 x 108 CFU/g, meeting probiotic criteria, with a pH of 3.85.

Evaluasi Peran Otoritas Jasa Keuangan dalam Pengawasan Implementasi Standar Audit 701 (2021)

The objectives of this study are to provide an overview of the benefits of communicating key audit matters (KAM) for OJK's oversight function, to identify findings related to KAM in United Kingdom and Malaysia, and how those regulators have responded to those findings, and to evaluate OJK's response related to KAM. This research is carried out by in-depth interviews with supervisors and analysts from the Directorate of Regulation and Development of the OJK Capital Market Sector. KAM communication provided benefits in OJK's supervisory function, among others, in determining the items to be reviewed in the Issuer's financial statements and in reviewing the audit responses stated in the auditor's report have been supported by the auditor's working papers. In carrying out their oversight function, the United Kingdom and Malaysia found, among others, that the average number of KAM and words in communicating KAM in the auditor's report continued to decline, the content of KAM of companies audited by Big 4 audit firms had more words for the same number of KAM, and the benefits of communicating KAM decreased because KAM disclosures were boilerplate. OJK's response in relation to the implementation of SA 701 (2021) is to draft OJK regulations related to KAM and to prepare a study related to the first-year implementation of SA 701 (2021). Based on these responses, it is reflected that OJK has an important role in the implementation support stage to ensure that the policy implementation runs well in the long term.

Impact of Norepinephrine and Dopamine Infusion on Renal Arterial Resistive Index during Pre-Emptive Living Donor Kidney Transplantation: Propensity Score Matching Analysis.

Background: Living donor kidney transplantation (LDKT) is a crucial treatment for end-stage renal disease, with pre-emptive LDKT (transplantation before dialysis initiation) offering significant benefits in graft function and patient survival. The selection of a vasopressor during LDKT, particularly between norepinephrine and dopamine, and its impact on renal arterial hemodynamics measured using the renal arterial resistive index (RARI) is poorly understood. Methods: This retrospective observational cohort study enrolled 347 eligible pre-emptive LDKT recipients from the Seoul St. Mary's Hospital between January 2019 and June 2023. Utilizing propensity score matching (PSM), the patients were categorized into dopamine and norepinephrine groups to compare the effects of these vasopressors on the intraoperative RARI, postoperative estimated glomerular filtration rate (eGFR), and hourly urine output. The RARI was measured via the Doppler ultrasonography of the renal hilum and parenchyma post-graft vascular and ureteral anastomoses. Results: The preoperative differences in the recipients' and donors' characteristics were mitigated following PSM. The dopamine group exhibited higher intraoperative RARI values at the renal hilum (0.77 ± 0.11 vs. 0.66 ± 0.13, p < 0.001) and parenchyma (0.71 ± 0.1 vs. 0.6 ± 0.1, p < 0.001) compared to those of the norepinephrine group. However, these differences were not statistically significant on postoperative day 7. The norepinephrine infusion adjusted for the propensity scores was associated with significantly lower odds of an RARI > 0.8 (hilum: OR = 0.214, 95% CI = 0.12-0.382, p < 0.001; parenchyma: OR = 0.1, 95% CI = 0.029-0.348, p < 0.001). The early postoperative outcomes showed a higher eGFR (day 1: 30.0 ± 13.3 vs. 25.1 ± 17.4 mL/min/1.73 m2, p = 0.004) and hourly urine output (day 1: 41.8 ± 16.9 vs. 36.5 ± 14.4 mL/kg/h, p = 0.002) in the norepinephrine group. Furthermore, the long-term outcomes were comparable between the groups. Conclusions: Norepinephrine infusion during pre-emptive LDKT is associated with more favorable intraoperative renal arterial hemodynamics, as evidenced by a lower RARI and improved early postoperative renal function compared to those of dopamine. These findings suggest a potential preferential role for norepinephrine in optimizing perioperative management and early graft functions in LDKT recipients. Given the retrospective nature of this study, further prospective studies are needed to confirm these observations. Additionally, the study limitations include the potential for unmeasured confounding factors and the inability to determine causality due to its observational design.

Reducing Left Ventricular Wall Stress through Aortic Valve Enlargement via Transcatheter Aortic Valve Implantation in Severe Aortic Stenosis.

Background: In aortic stenosis, the left ventricle exerts additional force to pump blood through the narrowed aortic valve into the downstream arterial vasculature. Adaptive hypertrophy helps to maintain wall stress homeostasis but at the expense of impaired compliance. Advanced ventricular deformation impacts the extent of functional recovery benefits achieved through transcatheter aortic valve implantation. Methods and Results: Subgroups were stratified based on output, with low-flow severe aortic stenosis defined as stroke volume index <35 mL· m-2. Before intervention, the low-flow subgroup exhibited worse effective orifice area index and arterial and global impedance, along with thinner wall thickness and larger chamber volume marginally. LV performance, including stroke volume index, ventricular elastance, and ventricular-arterial coupling, were notably inferior, consistent with worse adverse remodeling. Although the effective orifice area index was similarly augmented after TAVI, inferior recovery benefits were noted. Persistently higher wall stress and energy consumption were observed, along with poorer ventricular-arterial coupling. These changes in wall stress showed an inverse relationship with alterations in wall thickness and were proportional to changes in dimension and volume. Additionally, they were proportional to changes in left ventricular end-systolic pressure, pressure-volume area, and ventricular-arterial coupling but inversely related to ventricular end-systolic elastance. Conclusions: The study revealed that aortic valve enlargement through transcatheter aortic valve implantation reduces left ventricular wall stress in severe aortic stenosis. The reduced recovery benefits in the low-flow subgroup were evident. Wall stress could serve as a marker of mechanical benefit after the intervention.

An Outline on the Advancements in Surgical Management of Osteoporosis-Associated Fractures.

Osteoporosis significantly impairs bone density and increases fracture risk, representing a substantial global health challenge. The effectiveness of traditional treatments such as calcium supplementation and exercise in completely preventing fractures is limited. This review explores recent advancements in surgical techniques and treatment modalities to manage osteoporotic fractures better and improve patient outcomes. Osteoporotic fractures demand specialized surgical techniques due to compromised bone quality. Vertebroplasty and kyphoplasty are minimally invasive procedures that provide rapid pain relief and structural support using bone cement. While vertebroplasty is effective, it carries risks of cement leakage and new fractures. Kyphoplasty, with added balloon inflation, reduces leakage risk and improves vertebral height restoration but is costlier. Cement-augmented screws enhance fixation but can increase adjacent fracture risk and pose long-term complications. Surgical advancements encompass robotic-assisted surgery, offering precision and accelerated recovery, alongside biologic agents like bone morphogenetic proteins (BMPs), which enhance bone healing while reducing secondary interventions and eliminating donor site morbidity. Bone graft substitutes such as calcium phosphate cements enhance biomechanical compatibility, decrease morbidity, and reduce fracture loss and pain. Balloon kyphoplasty aids in height restoration and pain relief and diminishes the risk of subsequent vertebral fractures. Bioglass scaffolds promote bone regeneration by improving bone mineral density and lowering the incidence of new fractures. Optimal perioperative care, including patient selection, nutritional management, and early mobilization strategies, is crucial for mitigating risks in vulnerable populations. While current surgical interventions provide significant pain relief and functional benefits, ongoing research and multidisciplinary collaboration are crucial to prospectively refine these techniques and reduce the burden of osteoporosis. New technologies, such as tissue engineering and gene editing, hold potential for future treatment paradigms.

Perception of Brand Image Regarding to Brand Shopping Bags of Designers Brand Products

This study aimed to study the perception of brand image by consumers through shopping bags of world-class fashion brands such as Chanel, Gucci, Christian Dior, Celine, Furla. The data was collected using questionnaires from respondents who Aged between 25-45 years in Bangkok A total of 400 respondents were divided equally into males and females. The sample was selected using convenience random sampling from respondents who came to purchase products in department stores in Bangkok. The results of the study found that Respondents had a high level of awareness of brand value in terms of utility. As for the emotional and expressive aspects of brand value, It was found that respondents had a moderate level of perception of brand value. As for the results of the study of perceptions of the brand identity image displayed on shopping bags, it was found that the brand identity image has three components: functional benefits, symbolic benefits. and the benefits of the experience of using the product Its distinctiveness is at a moderate level.

How Much Physical Activity Is Needed for 75 Year and Older Adults: Using NHANES Datasets

&amp;lt;i&amp;gt;Targets&amp;lt;/i&amp;gt;: To examine the amount/level of Physical Activity (PA) needed to generate the most health benefits in noninstitutionalized 75 year and older U.S. resident adults. Intervention description: A total of 598 sample participants aged 75 year and above from National Health And Nutrition Examination Survey (NHANES) 2005-2006 datasets were included. Actigraph-monitored daily step counts, self-reported PA duration (time spent in weekly PA) and weekly energy expenditure were used to describe PA level/amount. Functional ability was expressed using the total levels of difficulties in doing twenty-one types of daily activities. PRISM Dose-response Curves Stimulation Variable slope model was applied to examine the needed PA level/amount in the population. &amp;lt;i&amp;gt;Mechanisms of action&amp;lt;/i&amp;gt;: PA benefits functional health in 75 year and older adults. Older females aged 75- 84 year need at least 150 mins/ 800 kcal energy expenditure per week or 5,800 daily steps to reach the most functional benefits. Older men aged 75-84 year need walk about 5,800 steps/day to achieve higher level of functionality. Older adults aged 85 years and above need to spend about 240 minutes/week on PA to gain health benefits. &amp;lt;i&amp;gt;Outcomes&amp;lt;/i&amp;gt;: Older males generally need/engage in more amount of PA compared to their female counterparts. Between 75-84 year old male and female adults, PA intensity is more important/reflective in male for expressing PA amount, while time spent in PA is more meaningful to older females. There is no difference in needed PA amount between different genders in 85 year and older adults.

Glycal Forte® (calcium-stabilized glycerol), a novel feed ingredient, promotes rumen function in dairy cows

Abstract Good nutritional practices are essential to support the high milk production of modern dairy cows. This requires an active rumen microbial biomass which supplies microbial protein and short-chain fatty acids to the cow. Glycal Forte® (GF) a calcium-stabilised glycerol product, increased microbial biomass in an in vitro gas production study, by some 37%. The efficacy of GF was substantiated in a trial with high-producing dairy cows fed a TMR with or without GF for 28 d. Cows fed GF showed behaviour differences. Chewing was reduced from 710 GF vs 769 for the control (CON) min/d; P=0.01 and they spent more time in an inactive state (429 GF vs 383 CON min/d; P=0.01). There was a statistically significant improvement in feed efficiency with GF (2.19 CON vs 2.34 GF kg ECM/kg dry matter intake (DMI); P=0.03). Feed efficiency has an important bearing on costs and profitability of a dairy operation. Cows fed GF yielded an improved profit of $1.45 per cow per day over 28 d with an ROI of 2.23. Extrapolated to a 100 dairy cow herd for 28 d gave an additional profit of $4,060. Milk yields continued to show benefits for 70 d in milk (DIM) after the GF treatment was stopped, showed a numerical increase in milk yield of 3.2 kg/d. The benefits in rumen function continues after the feeding of GF had ceased. In summary, this trial with high-producing dairy cows was consistent with the in vitro trial data and showed that GF can improve rumen function manifested as less time chewing, more inactive time and most importantly, improved feed efficiency. This has both economic and environmental advantages in that dairy cow productivity can be enhanced solely by nutritional means

A 12-week Taijiquan practice improves balance control and functional fitness in fall-prone postmenopausal women.

Falls are the leading cause of accidental death among older persons, with postmenopausal women facing a greater hazard of falling due to osteoporosis. This study aimed to examine the effects of Taijiquan practice on balance control and functional fitness in at-risk females. Chinese women who self-reported a tendency to fall and had a baseline one-leg stand test time (4.1 s in the Taijiquan group) below the national average for their age group (60-64 years: 10.9 s, 65-69 years: 9.9 s) were assigned to either a control group (n = 26, mean age = 63.9 years) or a Taijiquan group (n = 24, mean age = 63.9 years). The Taijiquan group participated in a 12-week supervised intervention, while the control group maintained their daily activities. The average duration of each exercise session was 52 min. Static balance and functional fitness were assessed at the beginning and end of the intervention. After 12 weeks, the Taijiquan group significantly outperformed the control group in terms of balance, flexibility, and muscular fitness (all p < 0.05). Participants in the Taijiquan group improved their one-leg stand by 61.0% (+2.5 s, Hedge's g = 0.85), arm curl by 8.3% (+1.7 repetitions, g = 0.53), handgrip strength by 8.3% (+1.9 kg, g = 0.65), and sit-and-reach by 163.2% (+6.2 cm, g = 1.17). The improvement in balance, coupled with other functional fitness benefits, suggests that Taijiquan could serve as a useful exercise for older women with an elevated risk of falling.

Use of Toxic and Allergen Plants in Landscape Arrangements of Urban Historical Areas: The Case of Çeşme Castle (İzmir)

Urban historical areas and buildings are structures that provide important information, culture and tradition transfer from the past to the present. These places are both an effective tourism area and a part of urban life. In addition to the aesthetic, ecological and functional benefits of the plants to be used in urban historical areas, their allergenic and toxic effects should be paid attention. Exposure to plants with toxic effects may cause mild or serious adverse effects on human health. The study was carried out to identify toxic and allergenic plants in the historical area of Çeşme Castle and to make evaluations about the area. Plants were examined on site in the study area and photographs were taken. According to the literature, the allergenic effects, toxic status, toxic parts and active ingredient of the plant species were determined. The data obtained were analysed and as a result of the analyses; 30 plant species, 29 genera and 22 families were identified in the area. Toxic plant species ratio in the area was 53.33 % and allergenic plant species ratio was 36.66 %. According to their forms, toxic plant species ratio was 37.5 % and allergenic plant species ratio was 81.81 %, with the highest proportion found in tree form plant species. Among the identified plants, 5 species have both toxic and allergenic effects. Recommendations have been made regarding the use of poisonous and allergenic plants in the field. Recommendations was made regarding the use of toxic and allergenic plants in the area.