In this paper, the crystal plastic finite element method is used to study the influence of the transition zone position of Tailor Rolled Blank (TRB) on the bending deformation behavior and spring-back from the mesoscale. The polycrystalline plastic finite element bending model of TRB is established and the bending forming process was simulated. The results show that the B-shaped blank (the blank consists of thick zone and transition zone) has a uniform plastic deformation and a smaller spring-back value than the A-shaped blank (the blank consists of thin zone and transition zone). The stress-strain zone of the B-shaped blank is uniform spread from the bend zone to both sides, but the stress-strain area of the A-shaped blank is transferred to the transition zone, which makes the blank exhibit poor forming properties. And this deformation ununiformity makes the spring-back angle of the A-shaped blank larger than that of the B-shaped blank.