A redox-responsive low-viscosity, injectable hydrogel (LVI-gel) sensor with capabilities involving bimodal cancer detection via the incorporation of glutathione (GSH) and reactive oxygen species (ROS)-activated nanoparticles (PD-Cu2+) is proposed and made injectable with varying degrees of mineralization. The PD-Cu2+ complex, in the presence of overexpressed GSH and ROS, undergoes a structural change that causes a regain of fluorescence and a shift in conductivity, accompanied by the variations in the mechanical, and adhesive properties for cancer detection. The release of catechol moieties brought about by the structural change of the PD-Cu2+ complex influences the shift in hydrogen bonding, resulting in increased water uptake, further reducing viscosity (η decreases by 95.14 %) and increasing adhesiveness (360.28 % increase) in the presence of GSH 10 mM. The alterations in mechanical and electrical properties further affect the bending response via LCR (control: ΔR/R0 ∼ 0.55 and GSH 10 mM: ΔR/R0 ∼ 0.89), which was confirmed in vitro via wireless response with HeLa, PC-3, and B16F10 as cancer cells. The effect of Cu2+-catalyzed oxidation of GSH was observed in vivo from the immunohistochemical studies and the downregulation of transcription for GPx1/Rn18s. Additionally, increased superoxide dismutase (SOD2) and catalase (CAT) activity along with the downregulation of the oncogenic NFκβ and TNF gene are observed. Finally, the ex situ sensing activity was monitored by the shift in resistance and the wireless response, demonstrating the ease with which the sensor could diagnose.