Background and Aims : Evidence suggests a gap between clinical guideline development and successful real-world implementation, with an estimated 4 out of 10 patients receiving non-evidenced-based care.1 Ensuring research addresses the drivers of this evidence implementation gap is a key health priority. Involving clinicians and patients in research design can help to synthesise existing knowledge and generate key recommendations to guide research. We convened an expert panel, as first step to help guide a 2-year behavioural science research programme - Cardio Connect: which aims to explore barriers to achieving recommended LDL cholesterol goals.Methods: An expert panel of N=4 behavioural scientists, N=5 clinicians (cardiologists and lipidologists) and a patient organisation representative, from Germany, Italy, and UK, attended a 3-hour virtual meeting. Behavioural scientists proposed a mixed-methods research programme and invited discussion.Results: Key research guiding principles emerged from the experts discussion and experience: 1) explore experiences of treatment access inequality, accounting for regional differences; 2) explore ways to better empower patients; 3) understand differences in the application of clinical guidelines between clinical specialties; 4) explore perceptual factors (e.g. clinicians concerns) and practical barriers (e.g. financial restraints) to delivering evidence-based care from patients’ and clinicians’ perspectives. Experts also advised on ways to engage the clinical and patient community: 1) disseminate findings at local and disease specific conferences; 2) engage patient organisations to reach under-served patients.Conclusions: Research is needed to better understand the evidence-implementation gap in dyslipidaemia. This research programme will apply behavioural science and be co-designed with patient and clinical communities. Background and Aims : Evidence suggests a gap between clinical guideline development and successful real-world implementation, with an estimated 4 out of 10 patients receiving non-evidenced-based care.1 Ensuring research addresses the drivers of this evidence implementation gap is a key health priority. Involving clinicians and patients in research design can help to synthesise existing knowledge and generate key recommendations to guide research. We convened an expert panel, as first step to help guide a 2-year behavioural science research programme - Cardio Connect: which aims to explore barriers to achieving recommended LDL cholesterol goals. Methods: An expert panel of N=4 behavioural scientists, N=5 clinicians (cardiologists and lipidologists) and a patient organisation representative, from Germany, Italy, and UK, attended a 3-hour virtual meeting. Behavioural scientists proposed a mixed-methods research programme and invited discussion. Results: Key research guiding principles emerged from the experts discussion and experience: 1) explore experiences of treatment access inequality, accounting for regional differences; 2) explore ways to better empower patients; 3) understand differences in the application of clinical guidelines between clinical specialties; 4) explore perceptual factors (e.g. clinicians concerns) and practical barriers (e.g. financial restraints) to delivering evidence-based care from patients’ and clinicians’ perspectives. Experts also advised on ways to engage the clinical and patient community: 1) disseminate findings at local and disease specific conferences; 2) engage patient organisations to reach under-served patients. Conclusions: Research is needed to better understand the evidence-implementation gap in dyslipidaemia. This research programme will apply behavioural science and be co-designed with patient and clinical communities.
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