Behavioral Evidence Research Articles

Does sedentary behaviour cause spinal pain in children and adolescents? A systematic review with meta-analysis

ObjectiveTo evaluate whether sedentary behaviour is a risk or prognostic factor for spinal pain in children and adolescents. Specifically, to estimate the (1) direction and strength of the association; (2)...

Evidence of mating-motivated altruistic behavior in time spent on a shared online task.

Evidence of mating-motivated altruistic behavior in time spent on a shared online task.

Behavioral and electrophysiological evidence for preserved specific associative episodic memory in older adults

Aging is often linked to a decline in associative memory. Prior research has shown that older adults have difficulty retrieving specific associative memory but can retrieve gist associative memory when deliberately differentiating test pairs with different levels of specificity during associative recognition. In this study, we utilized the context reinstatement paradigm to examine whether older adults could retrieve specific memory in situations where associations do not necessarily need to be voluntarily retrieved. Thirty-five older adults were directed to intentionally link objects with unique background scenes during encoding. Subsequently, test objects were presented against either the reinstated or similar background scenes during a recognition memory task, where participants were required to identify whether the objects were old or new regardless of their background contexts. Event-related potentials (ERP) were recorded to uncover the electrophysiological correlates of specific associative episodic memory. Behavioral results revealed higher memory sensitivity for object recognition when the background scenes were reinstated than when those were similar in older adults. ERP results indicated that older adults exhibited a more prominent fronto-centrally distributed positivity during object recognition in the reinstated than in similar contexts. Our results suggest that older adults may preserve their ability to retrieve specific memory for associations through an involuntary, spontaneous recollection process, which holds important theoretical implications for age-related associative memory deficits.

The Influence of R&D Intensity on Supply Chain Transparency: Evidence From the Disclosure Substitution Perspective

ABSTRACTThis paper shows that the existence of disclosure‐related costs and benefits explains the influence of R&D intensity on supply chain transparency. We find that R&D‐active firms are more likely to redact supply chain identities but disclose supply chain distribution as a substitution. The effect of withholding (disclosing) the specific identities (distribution) of supply chain is more (less) pronounced when firms are in higher competitive industries or non–state‐owned enterprises. Our study provides evidence of disclosure substitution behavior in a unified voluntary setting of supply chain transparency and shows that partial disclosure of nonproprietary information may be optimal.

Human olfactory perception embeds fine temporal resolution within a single sniff.

A sniff in humans typically lasts one to three seconds and is commonly considered to produce a long-exposure shot of the chemical environment that sets the temporal limit of olfactory perception. To break this limit, we devised a sniff-triggered apparatus that controls odorant deliveries within a sniff with a precision of 18 milliseconds. Using this apparatus, we show through rigorous psychophysical testing of 229 participants (649 sessions) that two odorants presented in one order and its reverse become perceptually discriminable when the stimulus onset asynchrony is merely 60 milliseconds (Cohen's d = 0.48; 95% confidence interval, (55, 59); 120-millisecond difference). Discrimination performance improves with the length of stimulus onset asynchrony and is independent of explicit knowledge of the temporal order of odorants or the relative amount of odorant molecules accumulated in a sniff. Our findings demonstrate that human olfactory perception is sensitive to chemical dynamics within a single sniff and provide behavioural evidence for a temporal code of odour identity.

Seeing on the fly: Physiological and behavioral evidence show that space-to-space representation and processing enable fast and efficient performance by the visual system.

When we view the world, our eyes saccade quickly between points of interest. Even when fixating a target our eyes are not completely at rest but execute small fixational eye movements (FEMs). That vision is not blurred despite this ever-present jitter has seemingly motivated an increasingly popular theory denying the reliance of the visual system on pure spatial processing in favor of a space-to-time mechanism generated by the eye drifting across the image. Accordingly, FEMs are not detrimental but rather essential to good visibility. However, the space-to-time theory is incompatible with physiological data showing that all information is conveyed by the short neural volleys generated when the eyes land on a target, and with our faithful perception of briefly displayed objects, during which time FEMs have no effect. Another difficulty in rejecting the idea of image representation by the locations and nature of responding cells in favor of a timecode, is that somewhere, somehow, this code must be decoded into a parallel spatial one when reaching perception. Thus, in addition to the implausibility of generating meaningful responses during retinal drift, the space-to-time hypothesis calls for replacing efficient point-to-point parallel transmission with a cumbersome, delayed, space-to-time-to-space process. A novel physiological framework is presented here wherein the ability of the visual system to quickly process information is mediated by the short, powerful neural volleys generated by the landing saccades. These volleys are necessary and sufficient for normal perception without FEMs contribution. This mechanism enables our excellent perception of brief stimuli and explains that visibility is not blurred by FEMs because they do not generate useful information.

Assessing the consistency and sensitivity of the neural correlates of narrative stimuli using functional near-infrared spectroscopy

Abstract Investigating how the brain responds to rich and complex narratives, such as engaging movies, has helped researchers study higher-order cognition in 'real-world' scenarios. These neural correlates are particularly useful in populations where behavioural evidence of cognition alone is inadequate, such as children and certain patient populations. While this research has been primarily conducted in fMRI and EEG, whether functional near-infrared spectroscopy (fNIRS) can reliably detect these neural correlates at an individual level, which is required for effective use in these populations, has yet to be established. This study replicated widespread inter-subject correlations (ISCs) in the frontal, parietal and temporal cortices in fNIRS in healthy participants when they watched part of the TV episode Bang! You're Dead and listened to an audio clip from the movie Taken. Conversely, these ISCs were primarily restricted to temporal cortices when participants viewed scrambled versions of those clips. To assess whether these results were reliable at the single-participant level, two follow-up analyses were conducted. First, the consistency analysis compared each participant's ISCs against group results that excluded that individual. This approach found that 24/26 participants in Bang! You're Dead and 20/26 participants in Taken were statistically similar to the group. Second, the sensitivity analysis measured whether machine learning algorithms could decode between intact conditions and their scrambled counterparts. This approach yielded balanced accuracy scores of 81% in Bang! You're Dead and 79% in Taken. Overall, the neural correlates of narrative stimuli, as assessed by fNIRS, are reproducible across participants, supporting its broad application to clinical and developmental populations.

Evidence of gill migration in monogenean polyopisthocotylean Microcotyle sebastis larvae infesting Korean rockfish (Sebastes schlegelii)

In contrast to the well-documented motility of monopisthocotyleans within the monogenean group, the mobility of polyopisthocotyleans, such as Microcotyle sebastis, has largely been undocumented with empirical evidence. This study aimed to investigate the locomotion of the polyopisthocotylean parasite of M. sebastis, which infests Korean rockfish (Sebastes schlegelii), thereby providing tangible evidence of early behavior in polyopisthocotyleans. The oncomiracidium of M. sebastis demonstrated movement facilitated by the hamulus and bilateral cilia, aiding in directional changes and propulsion. In the gill filaments of M. sebastis larvae utilized both the hamulus and their entire body for initial movements, effectively navigating between gill filaments. The hamulus played a crucial role in the locomotion of the early larval stages before the development of three clamp pairs, after which it began to degenerate. This study presents concrete evidence of early mobility in polyopisthocotyleans like M. sebastis, offering insights that could inform aquaculture management strategies, particularly in the mitigation of parasite-induced damages.

Connector hubs in semantic network contribute to creative thinking.

Semantic memory offers a rich repository of raw materials (e.g., various concepts and connections between concepts) for creative thinking, represented as a semantic network. Similar to other networks, the semantic network exhibits a modular structure characterized by modules with dense internal connections and sparse connections between them. This organizational principle facilitates the routine storage and retrieval of information but may impede creativity. The present study investigated the effect of hub concepts with varying connection patterns on creative thinking from the perspective of a modular structured semantic network. By analyzing a large-scale semantic network, connector hubs (C-hubs) and provincial hubs (P-hubs) were identified based on their intra- and intermodule connections. These hubs were used as cue words in the alternative uses task, a widely used measure of creative thinking. Across four experiments, behavioral and neural evidence indicated that C-hubs facilitate the generation of more novel and remote ideas compared to P-hubs. However, this effect is predominantly observed in the early stage of the creative thinking process, involving changes in brain activation and functional connectivity in core regions of the default mode network and the frontoparietal network, including the dorsolateral prefrontal cortex, angular gyrus, and precuneus. Neural findings suggest that the superior performance of C-hubs relies on stronger interactions between automatic spreading activation, controlled semantic retrieval, and attentional regulation of salient information. These results provide insight into how concepts with varying semantic connection patterns facilitate and constrain different stages of the creative thinking process through the modular structure of semantic network. (PsycInfo Database Record (c) 2024 APA, all rights reserved).

Chunk Duration Limits the Learning of Multiword Chunks: Behavioral and Electroencephalogram Evidence from Statistical Learning.

Language comprehension involves the grouping of words into larger multiword chunks. This is required to recode information into sparser representations to mitigate memory limitations and counteract forgetting. It has been suggested that electrophysiological processing time windows constrain the formation of these units. Specifically, the period of rhythmic neural activity (i.e., slow-frequency neural oscillations) may set an upper limit of 2-3 sec. Here, we assess whether learning of new multiword chunks is also affected by this neural limit. We applied an auditory statistical learning paradigm of an artificial language while manipulating the duration of to-be-learnt chunks. Participants listened to isochronous sequences of disyllabic pseudowords from which they could learn hidden three-word chunks based on transitional probabilities. We presented chunks of 1.95, 2.55, and 3.15 sec that were created by varying the pause interval between pseudowords. In a first behavioral experiment, we tested learning using an implicit target detection task. We found better learning for chunks of 2.55 sec as compared to longer durations in line with an upper limit of the proposed time constraint. In a second experiment, we recorded participants' electroencephalogram during the exposure phase to use frequency tagging as a neural index of statistical learning. Extending the behavioral findings, results show a significant decline in neural tracking for chunks exceeding 3 sec as compared to both shorter durations. Overall, we suggest that language learning is constrained by endogenous time constraints, possibly reflecting electrophysiological processing windows.

How educational inequality affects family multichild behavior—evidence from super high schools

In a context characterized by the dual issues of educational inequality and problems with fertility, the internal relationship between these two factors requires further in-depth exploration. On the basis of data drawn from the China Family Panel Studies (CFPS) from 2010 to 2018, this paper investigates whether “super high schools” in cities represent a form of educational inequality, uses a combination of a two-way fixed effect model with the instrumental variable method to discuss the influence of this situation on family fertility and the corresponding transmission mechanism, develops a proportional risk regression model, and expands our understanding of the influence of educational inequality on the second-child birth interval. This study reveals that educational inequality significantly suppresses the number of family births and that the paths of action associated with this effect include both the explicit and implicit costs of education. The inhibitory effect of educational inequality on the number of family births varies according to urban grade, urban or rural classification, and the education levels attained by women. In addition to decreasing the number of family births, educational inequality increases the second-child birth interval. This paper not only enriches related research on family multichild behavior but also provides an educational reference for attempts to address the issue of continuously low fertility rates in China and establish a connection between population and educational economics.

Evidence of multiferroic behavior in sintered BaTiO3 obtained from high-energy ball-milled powders

Multiferroic BaTiO3 exhibiting ferroelectric and ferromagnetic behavior was synthesized via the high-energy ball milling of pure BaTiO3 (BTO) powders for durations ranging from 15 to 60 min, followed by pressing and sintering at 1200°C X-ray diffraction patterns of all synthesized samples predominantly revealed a BTO phase with a tetragonal structure and a secondary Ba12Fe28Ti15O84 (BFTO) phase. The BFTO phase was formed after milling for more than 30 min because of chemical interactions between the BTO powder and milling media. Vibrating sample magnetometry confirmed the ferromagnetic nature of the sintered pellets. The specific magnetization increased with increasing milling duration, reaching a maximum value of 1.15 emu/g after 60 min of milling. This increase can be attributed to the distortion of the crystal structure and presence of a secondary phase, as confirmed by scanning electron microscopy and energy-dispersive X-ray spectroscopy. Additionally, electrical characterization revealed the dielectric nature of the materials, with relative permittivity ranging from 500 to 1800, maximum spontaneous polarization from 9.77 to 11.31 μC/cm2, coercive field from 3.86 to 11.12 kV/cm, and AC conductivity from 1 x 10−6 to 1 x 10−3 S/cm. The method described in this study is a simple and cost-effective approach to produce multiferroic materials with ferroelectric and relaxor ferroelectric behavior at room temperature, broadening their potential for technological applications.

Preclinical evaluation of abuse potential of the peripherally-restricted kappa opioid receptor agonist HSK21542

HSK21542 is a peripherally-restricted kappa opioid receptor (KOR) agonist developed for pain treatment. Because of the CNS pharmacological concern of opioid receptor activation, such as physical dependence and addiction potential, an assessment of abuse potential of HSK21542 was required prior to marketing approval. The preclinical abuse potential assessments for HSK21542 included the following studies: 1) intravenous self-administration study to explore the relative reinforcing efficacy in rats self-administering remifentanil; 2) rat drug discrimination study to examine the pharmacological similarity of the interoceptive or subjective effects of HSK21542 in rats discriminating pentazocine; 3) rat conditioned place preference (CPP) paradigm to test the rewarding effects; 4) rat natural physical dependence-spontaneous withdrawal study in rats chronically treated with HSK21542; 5) naloxone-precipitated withdrawal assay following chronic HSK21542 exposure to evaluate its physical dependence potential. The results showed that HSK21542 was devoid of behavioral evidence of positive reinforcing effect and did not share similar discriminative stimulus effects with pentazocine. HSK21542 also did not produce CPP in rats. In addition, HSK21542 did not produce spontaneous withdrawal or naloxone-precipitated withdrawal in rats with chronic treatments. Collectively, these preclinical findings suggest that HSK21542 has no abuse potential in animals, which demonstrate low abuse potential in humans.

Patterns of Conflict and Post-Conflict Affiliation in Propithecus diadema and Eulemur fulvus

AbstractGroup-living in primates provides benefits but also entails competition and aggression. To retain the positive fitness-enhancing advantages of social bonding, individuals can reconcile past aggression. Reconciliation has been extensively studied in haplorrhine primates and occurs more frequently in more tolerant species, but whether this pattern extends to strepsirrhine primates, including lemurs, remains unclear, particularly given the differences in behavioral biology between the two primate suborders. We examined the occurrence of reconciliation behavior and its relationship with dominance hierarchy characteristics in wild populations of Propithecus diadema and Eulemur fulvus. We collected behavioral data on dominance and affiliation behaviors in the Maromizaha Protected Area, Madagascar, focusing on three P. diadema groups and two E. fulvus groups over 14 months between 2015 and 2020. The dominance hierarchies differed between species, with P. diadema exhibiting steeper within-group hierarchies than E. fulvus. We found evidence of reconciliation behavior in P. diadema, as affiliation was more likely to follow conflicts than during control periods, but we did not find this effect in E. fulvus. Furthermore, reconciliation tendencies in P. diadema were higher in male–male dyads and those with disparate ranks. These findings suggest that dominance hierarchy structure may be an important factor influencing reconciliation behavior across primates, although the nuances of the relationship seem to vary between our two strepsirrhine study species and traditional haplorrhine patterns. Further research is needed to determine whether these patterns are species-, site-, or group-specific. In conclusion, these results further our understanding of the differences between strepsirrhine and haplorrhine social evolution.

Bees that love tears: A review of Lisotrigona congregating at human and animal eyes (Hymenoptera: Apidae, Meliponini)

Stingless bees (Apinae: Meliponini) exhibit astonishing and unusual behaviours, including tear-drinking or lachryphagy. In this review, we summarize lachryphagy in stingless bees, providing updated insights into their taxonomy, foraging patterns, ecology, hosts, evolutionary origins, and potential for pathogen transmission. In Northern Thailand, marked workers of the minute stingless bees Lisotrigona cacciae (Nurse) and L. furva Engel repeatedly return to human eyes, harvesting tears in short bouts that can last for hours or even over multiple days. Behavioural evidence suggests the presence of specialized tear collectors within these species. Single, experienced individuals can harvest tears gently, going unnoticed by the host, though large congregations can become bothersome. Lachryphagy occurs year-round and appears to be driven by high protein content in tears, in addition to salt and water. While Lisotrigona also visit flowers for nectar and pollen, tear collection may supplement or even replace pollen protein when floral resources are scarce or absent in their restricted habitats. Confirmed hosts include humans, zebu, dogs, cats, rabbits, chickens, and yellow tortoises. Lachryphagy has also been reported in other species of Lisotrigona in India. Interestingly, the similarly minute and widespread Tetragonula fuscobalteata (Cameron) is not lachryphagous but sucks sweat, as do other stingless bees, including Lisotrigona, though all visit flowers. This review also examines the potential for pathogen transmission via tear-drinking, particularly concerning viruses entering through the ocular surface, and discusses the evolutionary origins of lachryphagy in stingless bees.

Hierarchical analysis of the sense of agency in schizophrenia: motor control, control detection, and self-attribution

The sense of agency refers to the feeling of initiating and controlling one’s actions and their resulting effects on the external environment. Previous studies have uncovered behavioral evidence of excessive self-attribution and, conversely, a reduction in the sense of agency in patients with schizophrenia. We hypothesize that this apparent paradox is likely to result from impairment in lower-level processes underlying the sense of agency, combined with a higher-level compensational bias. The present study employed three behavioral tasks utilizing the same stimuli and experimental design to systematically evaluate multiple factors that influence the sense of agency, including motor control, sensorimotor processing, and self-attribution. Participants’ real-time mouse movements were combined with prerecorded motions of others in ratios of 30/70, 55/45, or 80/20, with an additional angular bias of either 0° or 90°. Twenty-six patients with schizophrenia and 27 health control volunteers participated in the three tasks. Patients with schizophrenia performed significantly worse in the reaching and control detection tasks than healthy controls. However, their self-attribution in the control judgment task was comparable to that of the healthy controls. Patients with schizophrenia were impaired in motor control components and in the detection of control using sensorimotor information, but their evaluation of agency remained relatively less affected. This underscores the importance of distinguishing between different subcomponents when addressing the abnormal sense of agency in patients with schizophrenia. Subsequent cluster analysis revealed that the combined task performance accurately distinguished between the patients and healthy control participants.

What Is Faster than Where in Vocal Emotional Perception.

Voices carry a vast amount of information about speakers (e.g., emotional state; spatial location). Neuroimaging studies postulate that spatial ("where") and emotional ("what") cues are processed by partially independent processing streams. Although behavioral evidence reveals interactions between emotion and space, the temporal dynamics of these processes in the brain and its modulation by attention remain unknown. We investigated whether and how spatial and emotional features interact during voice processing as a function of attention focus. Spatialized nonverbal vocalizations differing in valence (neutral, amusement, anger) were presented at different locations around the head, whereas listeners discriminated either the spatial location or emotional quality of the voice. Neural activity was measured with ERPs of the EEG. Affective ratings were collected at the end of the EEG session. Emotional vocalizations elicited decreased N1 but increased P2 and late positive potential amplitudes. Interactions of space and emotion occurred at the salience detection stage: neutral vocalizations presented at right (vs. left) locations elicited increased P2 amplitudes, but no such differences were observed for emotional vocalizations. When task instructions involved emotion categorization, the P2 was increased for vocalizations presented at front (vs. back) locations. Behaviorally, only valence and arousal ratings showed emotion-space interactions. These findings suggest that emotional representations are activated earlier than spatial representations in voice processing. The perceptual prioritization of emotional cues occurred irrespective of task instructions but was not paralleled by an augmented stimulus representation in space. These findings support the differential responding to emotional information by auditory processing pathways.

Sense of Agency during Encoding Predicts Subjective Reliving.

Autonoetic consciousness (ANC), the ability to re-experience personal past events links episodic memory and self-consciousness by bridging awareness of oneself in a past event (i.e., during its encoding) with awareness of oneself in the present (i.e., during the reliving of a past event). Recent neuroscience research revealed a bodily form of self-consciousness, including the sense of agency (SoA) and the sense of body ownership (SoO) that are based on the integration of multisensory bodily inputs and motor signals. However, the relation between SoA and/or SoO with ANC is not known. Here, we used immersive virtual reality technology and motion tracking and investigated the potential association of SoA/SoO with ANC. For this, we exposed participants to different levels of visuomotor and perspectival congruency, known to modulate SoA and SoO, during the encoding of virtual scenes and collected ANC ratings 1 week after the encoding session. In a total of 74 healthy participants, we successfully induced systematic changes in SoA and SoO during encoding and found that ANC depended on the level of SoA experienced during encoding. Moreover, ANC was positively associated with SoA, but only for the scene encoded with preserved visuomotor and perspectival congruency, and such SoA-ANC coupling was absent for SoO and control questions. Collectively, these data provide behavioral evidence in a novel paradigm that links a key subjective component of bodily self-consciousness during encoding, SoA, to the subjective reliving of those encoded events from one's past, ANC.

On the lasting impact of mild traumatic brain injury on working memory: Behavioural and electrophysiological evidence

Despite increasing recognition of the significance of mild traumatic brain injury (mTBI), the long-term cognitive consequences of the injury remain unclear. More sensitive measures that can detect subtle cognitive changes and consideration of individual variability are needed to properly characterise cognitive outcomes following mTBI. Here, we used complex behavioural tasks, individual differences approaches, and electrophysiology to investigate the long-term cognitive effects of a history of mTBI. In Experiment 1, participants with self-reported mTBI history (n=82) showed poorer verbal working memory performance on the operation span task compared to control participants (n=88), but there were no group differences in visual working memory, multitasking, cognitive flexibility, attentional control, visuospatial ability, or information processing speed. Individual differences analyses revealed that time since injury and presence of memory loss predicted visual working memory capacity and visuospatial ability, respectively, in those with mTBI history. In Experiment 2, participants with mTBI history (n=20) again demonstrated poorer verbal working memory on the operation span task compared to control participants (n=38), but no group differences were revealed on a visuospatial complex span task or simpler visual working memory measures. We also explored the electrophysiological indices of visual working memory using EEG during a change detection task. No differences were observed in early sensory event-related potentials (P1, N1) or the later negative slow wave associated with visual working memory capacity. Together, these findings suggest that mTBI history may be associated with a lasting, isolated disruption in the subsystem underlying verbal working memory storage. The results emphasise the importance of sensitive cognitive measures and accounting for individual variability in injury characteristics when assessing mTBI outcomes.

Cultural Values Influence the Developmental Trajectory of Resistance to Social Influence Over the Course of Adolescence

ABSTRACTThe opinions of peers are among the most potent factors influencing human decision‐making. Research conducted in Western societies suggests that individuals become more resistant to peer influence from late adolescence to adulthood. It is unknown whether this developmental trajectory is universal across cultures. Through two cross‐national studies, we present consistent self‐report and behavioral evidence for culturally distinct developmental trajectories of resistance to peer influence (RPI). Our findings from the US samples replicated prior findings that reported increasing RPI. Yet, data from the Chinese participants were better fitted using a nonlinear model, displaying a U‐shaped trajectory with lowest RPI levels at around 20 years old. In contrast to the long‐held belief that increasing RPI from adolescence to early adulthood is a universal developmental trait, we propose that this developmental trajectory may depend on cultural context.