In order to solve the problem of poor network security protection performance of traditional network information security protection systems, the author proposes a network information security system control modeling based on deep learning data interaction. Adopt CY8C2453 type processor to improve system data exchange and data processing speed, enhance system stability through peripheral backplane, and evaluate network information security, at the same time, the authority management mechanism is set, and the general strategy form of the network attack and defense game is defined as a triple, calculate the attacked path in a certain network area and the defense strategy that the defender should choose, so as to complete the network information security protection based on the attack-defense game model. Experimental results show that: The number of attacked information of the system is 58 less than that of the traditional system; In the webpage attack, the number of attacked information of the designed system is 82 less than that of the traditional system; In the data interception attack, the number of attacked information of the designed system is 77 less than that of the traditional system. ConclusionUnder different attack behaviors, the number of successful attacks on the network information security protection system based on the attack-defense game model designed this time is less than the number of successful attacks on the traditional system, which improves the security of network information.