Abstract This manuscript presents findings from a preregistered mixed-method study involving 67,762 ecological momentary assessments and behavioral smartphone observations from 1,315 adults. The study investigates (a) momentary associations between mindless scrolling, goal conflict, and guilt over smartphone use, and (b) whether guilt experiences during the day culminate into lower well-being. Results indicate that individuals experienced more guilt over their smartphone use when they had mindlessly scrolled for a longer period and that experienced goal conflict partially mediated this relationship. Daily analyses revealed that mindless scrolling was also associated with small negative changes in well-being, and this relationship was partially mediated by guilt experienced over the same day. Individuals with less self-control were more prone to experiencing goal conflict after mindlessly scrolling. These findings indicate that although mindless scrolling may seem a relatively harmless media behavior, it may have both momentary and downstream negative implications for well-being.