Behavioral Genetics Research Articles

Awards Presented at the 54th Annual Meeting of the Behavior Genetics Association, June 29th 2024, London, United Kingdom.

Awards Presented at the 54th Annual Meeting of the Behavior Genetics Association, June 29th 2024, London, United Kingdom.

Abstracts of the 54th Annual Meeting of the Behavior Genetics Association, London, UK : Program chair: Prof. Chandra Reynolds.

Abstracts of the 54th Annual Meeting of the Behavior Genetics Association, London, UK : Program chair: Prof. Chandra Reynolds.

An Evolutionary Perspective on Dog Behavioral Genetics.

Dogs have played an outsized role in the field of behavioral genetics since its earliest days. Their unique evolutionary history and ubiquity in the modern world make them a potentially powerful model system for discovering how genetic changes lead to changes in behavior. Genomic technology has supercharged this potential by enabling scientists to sequence the DNA of thousands of dogs and test for correlations with behavioral traits. However, fractures in the early history of animal behavior between biological and psychological subfields may be impeding progress. In addition, canine behavioral genetics has included almost exclusively dogs from modern breeds, who represent just a small fraction of all dog diversity. By expanding the scope of dog behavior studies, and incorporating an evolutionary perspective on canine behavioral genetics, we can move beyond associations to understanding the complex interactions between genes and environment that lead to dog behavior.

Announcement of the Editors' Choice Award (Formerly the Fulker Award) for a Paper Published in Behavior Genetics, Volume 53, 2023.

Announcement of the Editors' Choice Award (Formerly the Fulker Award) for a Paper Published in Behavior Genetics, Volume 53, 2023.

Minutes of the Annual Business Meeting of the Members of the Behavior Genetics Association. June 29, 2024, 11.50-13:00, Venue 'Bush House' London (United Kingdom).

Minutes of the Annual Business Meeting of the Members of the Behavior Genetics Association. June 29, 2024, 11.50-13:00, Venue 'Bush House' London (United Kingdom).

A new high-quality genome assembly and annotation for the threatened Florida Scrub-Jay (Aphelocoma coerulescens).

The Florida Scrub-Jay (Aphelocoma coerulescens), a Federally Threatened, cooperatively-breeding bird, is an emerging model system in evolutionary biology and ecology. Extensive individual-based monitoring and genetic sampling for decades has yielded a wealth of data, allowing for the detailed study of social behavior, demography, and population genetics of this natural population. Here, we report a linkage map and a chromosome-level genome assembly and annotation for a female Florida Scrub-Jay made with long-read sequencing technology, chromatin conformation data, and the linkage map. We constructed a linkage map comprising 4,468 SNPs that had 34 linkage groups and a total sex-averaged autosomal genetic map length of 2446.78 cM. The new genome assembly is 1.33 Gb in length, consisting of 33 complete or near-complete autosomes and the sex chromosomes (ZW). This highly contiguous assembly has an NG50 of 68 Mb and a Benchmarking Universal Single-Copy Orthologs (BUSCO) completeness score of 97.1% with respect to the Aves database. The annotated gene set has a BUSCO transcriptome completeness score of 95.5% and 17,964 identified protein-coding genes, 92.5% of which have associated functional annotations. This new, high-quality genome assembly and linkage map of the Florida Scrub-Jay provides valuable tools for future research into the evolutionary dynamics of small, natural populations of conservation concern.

A Social Constructionist Critique of Genetic Determinism

ABSTRACTRecently genetic determinist claims have reappeared in the explanation of human psychology and to some extent they even made their way into explanations of social phenomena. In this article, I will provide a critical analysis of the genetic determinist discourse from a social constructionist perspective. First, I will examine the meaning of genetic determinism. Then I will shortly introduce the social constructionist perspective generally and it's relevance for analyzing scientific discourses. Next, I will examine the debates about genetic determinism in behavior genetics and sociogenomics and interpret these critically from a social constructionist and deconstructionist perspective. Finally, I will provide an analysis of the main social, ideological, cultural and economic factors that influence the development of genetic determinist ideas: modernity, the legitimation of social hierarchies, neoliberalism and business interests. My conclusion is that the social constructionist perspective is important in the analysis and critique of the genetic determinist discourse.

Social Background Effects on Educational Outcomes—New Insights from Modern Genetic Science

Sociological theory and empirical research have found that parents’ socioeconomic status and related resources affect their children’s educational outcomes. Findings from behavior genetics reveal genetic underpinnings of the intergenerational transmission of education, thus altering previous conclusions about purely environmental transmission mechanisms. In recent years, studies in molecular genetics have led to new insights. Genomic data, polygenic scores, and other facets of sociogenomics are increasingly used to advance research in social stratification. Notably, the 2018 discovery of “genetic nurture” suggested that parents’ genes influence children above and beyond the genes they directly transmitted to their children. Such indirect genetic effects can be interpreted as consequences of parental behavior, which is itself influenced by the parents’ genetics and is essential for their children’s environment. Indirect genetic effects fit hand in glove with the sociological literature because they represent environmental transmission mechanisms. For instance, parenting behaviors, which are partly influenced by parents’ genes, shape children’s home environments and possibly their later educational outcomes. However, current findings based on more sophisticated research designs demonstrate that “genetic nurture” effects are actually much smaller than initially assumed and hence call for a reevaluation of common narratives found in the social stratification literature. In this paper, we review recent developments and ongoing research integrating molecular genetics to study educational outcomes, and we discuss their implications for sociological stratification research.

From Behavioral Genetics to Idiographic Science: Methodological Developments and Applications Inspired by the Work of Peter C. M. Molenaar

This special issue is a collection of papers inspired by Dr. Molenaar’s work and innovations – a tribute to his passion for advancing science and his ability to ignite a spark of creativity and innovation in multiple generations of scientists. Following Dr. Molenaar’s creative breadth, the papers address a wide variety of topics – sharing of new methodological developments, ideas, and findings in idiographic science, study of intraindividual variation, behavioral genetics, model inference/identification/selection, and more.

Relationship between walking movement and reproductive traits in the red flour beetle Tribolium castaneum

AbstractMany animal species have movement abilities. Behavior is important for evolutionary ecology because animal movement leads to dispersal, migration, search for food and mates, and escaping from enemies. However, individual differences in movement activity are found within a population. This phenomenon can be affected by various factors, one of which is suggesting that higher moving activity has fitness cost, whereas lower moving activity has benefits. Animal movement may also affect reproduction (e.g., resource allocation tradeoff between movement and reproduction as well as intra‐ and intersexual selection). Although many previous studies have investigated the relationship between movement and reproduction, less attention has been paid to walking movement. In this study, previous studies that investigated the relationship between movement and reproduction were reviewed using the flour beetle Tribolium castaneum, a model insect in behavioral ecology and genetics. Several previous studies suggest that beetle walking is strongly associated with male and female reproductive traits. In recent years, empirical studies on the correlation between walking and other traits have increased, particularly in T. castaneum. Although this species can fly and walk, the movement is often discussed without discriminating between flight and walk. Differences in modes of movement may affect the correlation between movement and other traits; thus, discussing each mode of movement separately is necessary.

Sex Differences in the Etiology of Victimization in Adulthood.

Until relatively recently, the study of victimization has been largely outside the purview of behavioral geneticists and evolutionary psychologists. Recent victimology research, however, has shown that genetic and evolutionary forces are connected to the risk of victimization. The current study expands on these findings by examining whether genetic influences differentially explain victimization in males and females. To do so, we use a sample of sibling pairs drawn from the National Longitudinal Study of Adolescent to Adult Health (Add Health; N = 4,244). The analyses revealed no significant quantitative sex differences in the etiology of adult victimization. However, the results of this study do highlight the importance of accounting for genetic factors when studying the etiology of specific types of adult victimization. We conclude by discussing the implications of the current study for future research.

THE PSYCHOLOGICAL FOUNDATIONS AND APPLICATIONS OF DIRECTIVE COMMUNICATION PSYCHOLOGY: AN OVERVIEW

Directive Communication (DC) Psychology, initially developed by Arthur F. Carmazzi in 2001, is an emerging field that explores the complexities of group behavior and individual performance in organizational settings. By integrating concepts from motivational and genetic psychology, this framework provides insights into how individuals interact within and are influenced by specific groups. This paper aims to dissect the key tenets of DC Psychology, examine its assumptions, and explore its applications in both commercial and non-commercial environments. The study also highlights empirical evidence supporting the efficacy of DC Psychology and suggests areas for further research.

A personality SNP? Behavioral genetics in African cichlids

Speciation is familiar in radiations, but personality is not. In a recent article, Sommer-Trembo et al. linked exploratory behavior in African cichlids to a SNP in the promoter of a gene, the homolog of which is associated with human personality disorders, offering clues about the first fish of this radiation, with implications for vertebrate evolution.

C. Robert Cloninger: Mechanisms and conditions by which temperament, character, and personality development can regulate health and well-being

Dr. C. Robert Cloninger's contributions have been foundational in understanding temperament, personality, and their biological and genetic underpinnings. Cloninger explored how temperament, character, and personality traits are influenced by genetic factors and how they predict various psychological disorders, such as alcoholism and personality disorders. His prospective studies involving adoptees reared apart from their biological parents provided crucial insights into the heritability and development of personality traits independent of environmental influences. Moreover, Cloninger's pioneering work in conducting the first genome-wide association and linkage studies of normal personality traits laid the groundwork for subsequent research in psychiatry and behavioral genetics, linking specific genetic profiles to patterns of temperament and personality. He is also the creator of two extensively employed personality assessment instruments: the Tridimensional Personality Questionnaire (TPQ) and the Temperament and Character Inventory (TCI). Dr. Cloninger serves as Director of the Anthropedia Institute and Professor Emeritus at Washington University in St. Louis, where he studies the biopsychosocial foundations of personality that influence health and illness. The Anthropedia Institute is the research branch of the Anthropedia Foundation, a non-profit organization dedicated to the promotion of human well-being through initiatives in health care and education. He served as Wallace Renard Professor of Psychiatry & Genetics, Professor of Psychological and Brain Sciences, and founding Director of the Sansone Center for Well-being at Washington University until July 2019. Dr. Cloninger is a member of the National Academy of Medicine USA, Fellow of the American Academy for Advancement of Science, and an editor of various journals in psychiatry, psychology, and genetics. We are pleased to share Dr. Cloninger's answers to the Genomic Press Interview.

Genes and gene networks underlying spatial cognition in food-caching chickadees

Substantial progress has been made in understanding the genetic architecture of phenotypes involved in a variety of evolutionary processes. Behavioral genetics remains, however, among the least understood. We explore the genetic architecture of spatial cognitive abilities in a wild passerine bird, the mountain chickadee (Poecile gambeli). Mountain chickadees cache thousands of seeds in the fall and require specialized spatial memory to recover these caches throughout the winter. We previously showed that variation in spatial cognition has a direct effect on fitness and has a genetic basis. It remains unknown which specific genes and developmental pathways are particularly important for shaping spatial cognition. To further dissect the genetic basis of spatial cognitive abilities, we combine experimental quantification of spatial cognition in wild chickadees with whole-genome sequencing of 162 individuals, a new chromosome-scale reference genome, and species-specific gene annotation. We have identified a set of genes and developmental pathways that play a key role in creating variation in spatial cognition and found that the mechanism shaping cognitive variation is consistent with selection against mildly deleterious non-coding mutations. Although some candidate genes were organized into connected gene networks, about half do not have shared regulation, highlighting that multiple independent developmental or physiological mechanisms contribute to variation in spatial cognitive abilities. A large proportion of the candidate genes we found are associated with synaptic plasticity, an intriguing result that leads to the hypothesis that certain genetic variants create antagonism between behavioral plasticity and long-term memory, each providing distinct benefits depending on ecological context.

Why human behavioral ecology needs behavioral genetics: The problem of phenotypic gambit.

Why human behavioral ecology needs behavioral genetics: The problem of phenotypic gambit.

Exploring the comorbidity between internalizing/externalizing dimensions and cognitive disengagement syndrome through twin studies: a narrative review

Twin studies are cutting-edge design methodologies proper to behavioral genetics that aim to investigate how the interplay between genetic and environmental factors can concur to explain individual differences in psychopathology, temperamental traits, and behavior. This particular research design has been widely applied to the study of comorbidity between internalizing (INT) and externalizing (EXT) symptoms, especially in childhood and adolescence. Notably, the high co-occurrence of symptoms of both these diagnostic domains has led to the hypothesis that at their basis, there might be one single latent common susceptibility factor, namely p factor. Twin studies have contributed to marking a relevant turning point in this regard by highlighting the consistent genetic nature of this factor. In light of these premises, the present narrative review aims to outline the path for future twin studies in investigating the comorbidity between Cognitive Disengagement Syndrome (CDS) and INT-EXT disorders, examining the evidence supporting this need and its clinical implications. Since CDS has not been recognized as a stand-alone syndrome until very recently, research on this condition is still in its infancy and the etiological factors at the basis of its comorbidity with INT-EXT are still unclear. Being aware of the causal factors underneath the comorbidity between INT-EXT might pave the way for improving assessment diagnostic procedures as well as setting up preventive interventions for CDS.

Heritability within groups is uninformative about differences among groups: Cases from behavioral, evolutionary, and statistical genetics

Without the ability to control or randomize environments (or genotypes), it is difficult to determine the degree to which observed phenotypic differences between two groups of individuals are due to genetic vs. environmental differences. However, some have suggested that these concerns may be limited to pathological cases, and methods have appeared that seem to give-directly or indirectly-some support to claims that aggregate heritable variation within groups can be related to heritable variation among groups. We consider three families of approaches: the "between-group heritability" sometimes invoked in behavior genetics, the statistic [Formula: see text] used in empirical work in evolutionary quantitative genetics, and methods based on variation in ancestry in an admixed population, used in anthropological and statistical genetics. We take up these examples to show mathematically that information on within-group genetic and phenotypic information in the aggregate cannot separate among-group differences into genetic and environmental components, and we provide simulation results that support our claims. We discuss these results in terms of the long-running debate on this topic.

Gene-environment interaction analysis of school quality and educational inequality

We study to what extent schools increase or decrease environmental and genetic influences on educational performance. Building on behavioral genetics literature on gene-environment interactions and sociological literature on the compensating and amplifying effects of schools on inequality, we investigate whether the role of genes and the shared environment is larger or smaller in higher-quality school environments. We apply twin models to Dutch administrative data on the educational performance of 18,384 same-sex and 11,050 opposite-sex twin pairs, enriched with data on the quality of primary schools. Our results show that school quality does not moderate genetic and shared-environmental influences on educational performance once the moderation by SES is considered. We find a gene-environment interplay for school SES: genetic variance decreases with increasing school SES. This school SES effect partly reflects parental SES influences. Yet, parental SES does not account for all the school SES moderation, suggesting that school-based processes play a role too.

Nonshared environment: Real but random.

In the excitement about genomics, it is easy to lose sight of one of the most important findings from behavioural genetics: At least half of the variance of psychopathology is caused by environmental effects that are not shared by children growing up in the same family, which includes error of measurement. However, a 30-year search for the systematic causes of nonshared environment in a line-up of the usual suspects, especially parenting, has not identified the culprits. I briefly review this research, but primarily consider the conceptual framework of the search for 'missing' nonshared environmental effects. The search has focused on exogenous events like parenting, but nonshared environment might not be caused by anything we would call an event. Instead, it might reflect endogenous processes such as noisy biological systems (such as somatic mutations and epigenetics) or, at a psychological level, idiosyncratic subjective perceptions of past and present experiences, which could be called nonshared environmental experience to distinguish it from exogenous events. Although real, nonshared environment might be random in the philosophy of science sense of being unpredictable, even though it can have stable effects that predict subsequent behaviour. I wade into the weeds of randomness and suggest that this so-called 'gloomy prospect' might not be so gloomy.